Compile Data Set for Download or QSAR

Found 26 hits Enz. Inhib. hit(s) with all data for entry = 50016546   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170306 (1-(2,2-Dimethyl-propyl)-4-propyl-5-[4'-(1H-tetrazo...) Show SMILES CCCc1c(OCc2cccc(c2)-c2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)ccc12 Show InChI InChI=1S/C30H33N5O/c1-5-7-26-25-16-17-35(20-30(2,3)4)27(25)14-15-28(26)36-19-21-8-6-9-24(18-21)22-10-12-23(13-11-22)29-31-33-34-32-29/h6,8-18H,5,7,19-20H2,1-4H3,(H,31,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	318	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170327 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{5-[4-(1H-tetra...) Show SMILES CCCc1c(OCCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)ccc12 Show InChI InChI=1S/C28H37N5O2/c1-5-9-24-23-16-17-33(20-28(2,3)4)25(23)14-15-26(24)35-19-8-6-7-18-34-22-12-10-21(11-13-22)27-29-31-32-30-27/h10-17H,5-9,18-20H2,1-4H3,(H,29,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.01E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170308 (1-(2,2-Dimethyl-propyl)-5-{4-[4-(1H-tetrazol-5-yl)...) Show SMILES CC(C)(C)Cn1ccc2cc(OCCCCOc3ccc(cc3)-c3nnn[nH]3)ccc12 Show InChI InChI=1S/C24H29N5O2/c1-24(2,3)17-29-13-12-19-16-21(10-11-22(19)29)31-15-5-4-14-30-20-8-6-18(7-9-20)23-25-27-28-26-23/h6-13,16H,4-5,14-15,17H2,1-3H3,(H,25,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.59E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170309 (1-(2,2-Dimethyl-propyl)-4-propyl-5-[3-(1H-tetrazol...) Show SMILES CCCc1c(Oc2cccc(c2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)ccc12 Show InChI InChI=1S/C23H27N5O/c1-5-7-19-18-12-13-28(15-23(2,3)4)20(18)10-11-21(19)29-17-9-6-8-16(14-17)22-24-26-27-25-22/h6,8-14H,5,7,15H2,1-4H3,(H,24,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	134	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170310 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...) Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)ncc12 Show InChI InChI=1S/C26H34N6O2/c1-5-8-21-22-17-27-32(18-26(2,3)4)23(22)13-14-24(21)34-16-7-6-15-33-20-11-9-19(10-12-20)25-28-30-31-29-25/h9-14,17H,5-8,15-16,18H2,1-4H3,(H,28,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	984	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170312 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...) Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)nnc12 Show InChI InChI=1S/C25H33N7O2/c1-5-8-20-22(14-13-21-23(20)26-31-32(21)17-25(2,3)4)34-16-7-6-15-33-19-11-9-18(10-12-19)24-27-29-30-28-24/h9-14H,5-8,15-17H2,1-4H3,(H,27,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	936	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 expressed in HEK293 cells done for 1 ...				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170311 (1,4-Dipropyl-5-{4-[4-(1H-tetrazol-5-yl)-phenoxy]-b...) Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CCC)ccc12 Show InChI InChI=1S/C25H31N5O2/c1-3-7-22-21-14-16-30(15-4-2)23(21)12-13-24(22)32-18-6-5-17-31-20-10-8-19(9-11-20)25-26-28-29-27-25/h8-14,16H,3-7,15,17-18H2,1-2H3,(H,26,27,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	652	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170313 (4-Bromo-1-(2,2-dimethyl-propyl)-5-{4-[4-(1H-tetraz...) Show SMILES CC(C)(C)Cn1ccc2c(Br)c(OCCCCOc3ccc(cc3)-c3nnn[nH]3)ccc12 Show InChI InChI=1S/C24H28BrN5O2/c1-24(2,3)16-30-13-12-19-20(30)10-11-21(22(19)25)32-15-5-4-14-31-18-8-6-17(7-9-18)23-26-28-29-27-23/h6-13H,4-5,14-16H2,1-3H3,(H,26,27,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	2.26E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170314 (1-(2,2-Dimethyl-propyl)-4-methyl-5-{4-[4-(1H-tetra...) Show SMILES Cc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)ccc12 Show InChI InChI=1S/C25H31N5O2/c1-18-21-13-14-30(17-25(2,3)4)22(21)11-12-23(18)32-16-6-5-15-31-20-9-7-19(8-10-20)24-26-28-29-27-24/h7-14H,5-6,15-17H2,1-4H3,(H,26,27,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170315 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...) Show SMILES CCCc1c2CCN(CC(C)(C)C)c2ccc1OCCCCOc1ccc(cc1)-c1nnn[nH]1 Show InChI InChI=1S/C27H37N5O2/c1-5-8-23-22-15-16-32(19-27(2,3)4)24(22)13-14-25(23)34-18-7-6-17-33-21-11-9-20(10-12-21)26-28-30-31-29-26/h9-14H,5-8,15-19H2,1-4H3,(H,28,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	1.17E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170317 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{3-[4-(1H-tetra...) Show SMILES CCCc1c(OCc2cccc(Oc3ccc(cc3)-c3nnn[nH]3)c2)ccc2n(CC(C)(C)C)ccc12 Show InChI InChI=1S/C30H33N5O2/c1-5-7-26-25-16-17-35(20-30(2,3)4)27(25)14-15-28(26)36-19-21-8-6-9-24(18-21)37-23-12-10-22(11-13-23)29-31-33-34-32-29/h6,8-18H,5,7,19-20H2,1-4H3,(H,31,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	451	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170316 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...) Show SMILES CCCc1c(OCc2ccc(Oc3ccc(cc3)-c3nnn[nH]3)cc2)ccc2n(CC(C)(C)C)ccc12 Show InChI InChI=1S/C30H33N5O2/c1-5-6-26-25-17-18-35(20-30(2,3)4)27(25)15-16-28(26)36-19-21-7-11-23(12-8-21)37-24-13-9-22(10-14-24)29-31-33-34-32-29/h7-18H,5-6,19-20H2,1-4H3,(H,31,32,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	879	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170319 (1-Pentyl-4-propyl-5-{4-[4-(1H-tetrazol-5-yl)-pheno...) Show SMILES CCCCCn1ccc2c(CCC)c(OCCCCOc3ccc(cc3)-c3nnn[nH]3)ccc12 Show InChI InChI=1S/C27H35N5O2/c1-3-5-6-17-32-18-16-23-24(9-4-2)26(15-14-25(23)32)34-20-8-7-19-33-22-12-10-21(11-13-22)27-28-30-31-29-27/h10-16,18H,3-9,17,19-20H2,1-2H3,(H,28,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	598	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170318 (1-(2,2-Dimethyl-propyl)-2-methyl-4-propyl-5-{4-[4-...) Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)c(C)cc12 Show InChI InChI=1S/C28H37N5O2/c1-6-9-23-24-18-20(2)33(19-28(3,4)5)25(24)14-15-26(23)35-17-8-7-16-34-22-12-10-21(11-13-22)27-29-31-32-30-27/h10-15,18H,6-9,16-17,19H2,1-5H3,(H,29,30,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	559	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170320 (1-Isopropyl-4-propyl-5-{4-[4-(1H-tetrazol-5-yl)-ph...) Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(ccc12)C(C)C Show InChI InChI=1S/C25H31N5O2/c1-4-7-22-21-14-15-30(18(2)3)23(21)12-13-24(22)32-17-6-5-16-31-20-10-8-19(9-11-20)25-26-28-29-27-25/h8-15,18H,4-7,16-17H2,1-3H3,(H,26,27,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170321 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...) Show SMILES CCCc1c(OC\C=C\COc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)ccc12 Show InChI InChI=1S/C27H33N5O2/c1-5-8-23-22-15-16-32(19-27(2,3)4)24(22)13-14-25(23)34-18-7-6-17-33-21-11-9-20(10-12-21)26-28-30-31-29-26/h6-7,9-16H,5,8,17-19H2,1-4H3,(H,28,29,30,31)/b7-6+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	779	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50153757 (1-(2-Hydroxy-3-propyl-4-{4-[4-(1H-tetrazol-5-yl)-p...) Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc(C(C)=O)c1O Show InChI InChI=1S/C22H26N4O4/c1-3-6-19-20(12-11-18(15(2)27)21(19)28)30-14-5-4-13-29-17-9-7-16(8-10-17)22-23-25-26-24-22/h7-12,28H,3-6,13-14H2,1-2H3,(H,23,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	348	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170322 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...) Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)cnc12 Show InChI InChI=1S/C26H34N6O2/c1-5-8-21-23(14-13-22-24(21)27-18-32(22)17-26(2,3)4)34-16-7-6-15-33-20-11-9-19(10-12-20)25-28-30-31-29-25/h9-14,18H,5-8,15-17H2,1-4H3,(H,28,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	6.37E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170323 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{2-[4-(1H-tetra...) Show SMILES CCCc1c(OCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)ccc12 Show InChI InChI=1S/C25H31N5O2/c1-5-6-21-20-13-14-30(17-25(2,3)4)22(20)11-12-23(21)32-16-15-31-19-9-7-18(8-10-19)24-26-28-29-27-24/h7-14H,5-6,15-17H2,1-4H3,(H,26,27,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170312 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...) Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)nnc12 Show InChI InChI=1S/C25H33N7O2/c1-5-8-20-22(14-13-21-23(20)26-31-32(21)17-25(2,3)4)34-16-7-6-15-33-19-11-9-18(10-12-19)24-27-29-30-28-24/h9-14H,5-8,15-17H2,1-4H3,(H,27,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	188	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170325 (1-Cyclopropylmethyl-4-propyl-5-{4-[4-(1H-tetrazol-...) Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC3CC3)ccc12 Show InChI InChI=1S/C26H31N5O2/c1-2-5-23-22-14-15-31(18-19-6-7-19)24(22)12-13-25(23)33-17-4-3-16-32-21-10-8-20(9-11-21)26-27-29-30-28-26/h8-15,19H,2-7,16-18H2,1H3,(H,27,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	755	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170324 (1-Cyclohexylmethyl-4-propyl-5-{4-[4-(1H-tetrazol-5...) Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC3CCCCC3)ccc12 Show InChI InChI=1S/C29H37N5O2/c1-2-8-26-25-17-18-34(21-22-9-4-3-5-10-22)27(25)15-16-28(26)36-20-7-6-19-35-24-13-11-23(12-14-24)29-30-32-33-31-29/h11-18,22H,2-10,19-21H2,1H3,(H,30,31,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	228	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170328 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{3-[4-(1H-tetra...) Show SMILES CCCc1c(OCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)ccc12 Show InChI InChI=1S/C26H33N5O2/c1-5-7-22-21-14-15-31(18-26(2,3)4)23(21)12-13-24(22)33-17-6-16-32-20-10-8-19(9-11-20)25-27-29-30-28-25/h8-15H,5-7,16-18H2,1-4H3,(H,27,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	3.54E+3	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170329 (1-Isobutyl-4-propyl-5-{4-[4-(1H-tetrazol-5-yl)-phe...) Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)C)ccc12 Show InChI InChI=1S/C26H33N5O2/c1-4-7-23-22-14-15-31(18-19(2)3)24(22)12-13-25(23)33-17-6-5-16-32-21-10-8-20(9-11-21)26-27-29-30-28-26/h8-15,19H,4-7,16-18H2,1-3H3,(H,27,28,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	765	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170326 (1-(2,2-Dimethyl-propyl)-4-propyl-5-{4-[4-(1H-tetra...) Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2n(CC(C)(C)C)ccc12 Show InChI InChI=1S/C27H35N5O2/c1-5-8-23-22-15-16-32(19-27(2,3)4)24(22)13-14-25(23)34-18-7-6-17-33-21-11-9-20(10-12-21)26-28-30-31-29-26/h9-16H,5-8,17-19H2,1-4H3,(H,28,29,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	559	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 2 (Homo sapiens (Human))	BDBM50170307 (3-(2,2-Dimethyl-propyl)-7-propyl-6-{4-[4-(1H-tetra...) Show SMILES CCCc1c(OCCCCOc2ccc(cc2)-c2nnn[nH]2)ccc2c(CC(C)(C)C)noc12 Show InChI InChI=1S/C26H33N5O3/c1-5-8-21-23(14-13-20-22(17-26(2,3)4)29-34-24(20)21)33-16-7-6-15-32-19-11-9-18(10-12-19)25-27-30-31-28-25/h9-14H,5-8,15-17H2,1-4H3,(H,27,28,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	n/a	n/a	788	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description Effective concentration for stimulation of [35S]-GTP-gammaS, binding to human metabotropic glutamate receptor 2 incubated at 30 degree C for 1 hr				Bioorg Med Chem Lett 15: 4068-72 (2005) Article DOI: 10.1016/j.bmcl.2005.06.017 BindingDB Entry DOI: 10.7270/Q2Q52P6K
					More data for this Ligand-Target Pair