BindingDB PrimarySearch

Found 11 hits Enz. Inhib. hit(s) with all data for entry = 50016698
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50140541 ((S)-2-Amino-2-cyclohexyl-1-(3,3-difluoro-pyrrolidi...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC(F)(F)C1 \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50140527 ((S)-2-Amino-2-cyclohexyl-1-((S)-3-fluoro-pyrrolidi...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CC[C@H](F)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50172141 ((S)-2-Amino-2-cyclohexyl-1-(3,4-difluoro-pyrrolidi...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CC(F)C(F)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	61	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV calculated from IC50 from standard dose inhibition curve using cheng-Prussoff equation; range=61+/...				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50172144 ((S)-2-Amino-2-cyclohexyl-1-(2,3,4,5-tetrafluoro-py...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1C(F)C(F)C(F)C1F Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50172143 ((S)-2-Amino-2-cyclohexyl-1-(3-fluoro-azetidin-1-yl...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CC(F)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	109	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50172139 ((S)-2-Amino-2-cyclohexyl-1-(3,3-difluoro-azetidin-...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CC(F)(F)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	117	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM12191 ((2S)-2-amino-2-cyclohexyl-1-(pyrrolidin-1-yl)ethan...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCCC1 \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	121	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50140539 ((S)-2-Amino-2-cyclohexyl-1-((R)-3-fluoro-pyrrolidi...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CC[C@@H](F)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	128	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50172145 ((S)-2-Amino-2-cyclohexyl-1-((3R,4R)-3,4-difluoro-p...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	504	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50172140 ((S)-2-Amino-2-cyclohexyl-1-((3S,4S)-3,4-difluoro-p...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.27E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50172142 ((S)-2-Amino-1-azetidin-1-yl-2-cyclohexyl-ethanone ...) Show SMILES N[C@@H](C1CCCCC1)C(=O)N1CCC1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.35E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibitory constant against Dipeptidylpeptidase IV activity				Bioorg Med Chem Lett 15: 4770-3 (2005) Article DOI: 10.1016/j.bmcl.2005.07.026 BindingDB Entry DOI: 10.7270/Q28K78M0
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair