Compile Data Set for Download or QSAR

Found 104 hits Enz. Inhib. hit(s) with all data for entry = 50045731   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM120996 (US8716285, 53) Show SMILES ONC(=O)c1ccc2NCC(Cc2c1)Nc1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C19H18N6O2/c26-18(25-27)12-3-4-16-14(8-12)9-15(11-22-16)23-19-21-7-5-17(24-19)13-2-1-6-20-10-13/h1-8,10,15,22,27H,9,11H2,(H,25,26)(H,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078748 (CHEMBL3415629) Show SMILES C[C@@]1(CCN(C1=O)c1ccc(Cl)cc1)Nc1ccc(cc1)C(=O)NO |r| Show InChI InChI=1S/C18H18ClN3O3/c1-18(20-14-6-2-12(3-7-14)16(23)21-25)10-11-22(17(18)24)15-8-4-13(19)5-9-15/h2-9,20,25H,10-11H2,1H3,(H,21,23)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078747 (CHEMBL3415628) Show SMILES CC1(CCN(C1=O)c1ccc2ncccc2c1)Nc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C21H20N4O3/c1-21(23-16-6-4-14(5-7-16)19(26)24-28)10-12-25(20(21)27)17-8-9-18-15(13-17)3-2-11-22-18/h2-9,11,13,23,28H,10,12H2,1H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078695 (CHEMBL3415627) Show SMILES CC1(CCN(C1=O)c1ccc(Cl)cc1)Nc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C18H18ClN3O3/c1-18(20-14-6-2-12(3-7-14)16(23)21-25)10-11-22(17(18)24)15-8-4-13(19)5-9-15/h2-9,20,25H,10-11H2,1H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50027662 (CHEMBL3338418) Show SMILES ONC(=O)c1ccc2CC[C@H](Cc2c1)Nc1nccc(n1)-c1cccnc1 |r| Show InChI InChI=1S/C20H19N5O2/c26-19(25-27)14-4-3-13-5-6-17(11-16(13)10-14)23-20-22-9-7-18(24-20)15-2-1-8-21-12-15/h1-4,7-10,12,17,27H,5-6,11H2,(H,25,26)(H,22,23,24)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078687 (CHEMBL3415619) Show SMILES ONC(=O)c1ccc(NC2CCN(C2=O)c2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C17H15Cl2N3O3/c18-13-6-5-12(9-14(13)19)22-8-7-15(17(22)24)20-11-3-1-10(2-4-11)16(23)21-25/h1-6,9,15,20,25H,7-8H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078747 (CHEMBL3415628) Show SMILES CC1(CCN(C1=O)c1ccc2ncccc2c1)Nc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C21H20N4O3/c1-21(23-16-6-4-14(5-7-16)19(26)24-28)10-12-25(20(21)27)17-8-9-18-15(13-17)3-2-11-22-18/h2-9,11,13,23,28H,10,12H2,1H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	76	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50027662 (CHEMBL3338418) Show SMILES ONC(=O)c1ccc2CC[C@H](Cc2c1)Nc1nccc(n1)-c1cccnc1 |r| Show InChI InChI=1S/C20H19N5O2/c26-19(25-27)14-4-3-13-5-6-17(11-16(13)10-14)23-20-22-9-7-18(24-20)15-2-1-8-21-12-15/h1-4,7-10,12,17,27H,5-6,11H2,(H,25,26)(H,22,23,24)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078680 (CHEMBL3415454) Show SMILES ONC(=O)c1ccc(NC2CCN(C2=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C17H16ClN3O3/c18-12-2-1-3-14(10-12)21-9-8-15(17(21)23)19-13-6-4-11(5-7-13)16(22)20-24/h1-7,10,15,19,24H,8-9H2,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078690 (CHEMBL3415621) Show SMILES ONC(=O)c1ccc(NC2CCN(C2=O)c2ccc(cc2)C#N)cc1 Show InChI InChI=1S/C18H16N4O3/c19-11-12-1-7-15(8-2-12)22-10-9-16(18(22)24)20-14-5-3-13(4-6-14)17(23)21-25/h1-8,16,20,25H,9-10H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078682 (CHEMBL3415618) Show SMILES ONC(=O)c1ccc(NC2CCN(C2=O)c2ccc(cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C18H16F3N3O3/c19-18(20,21)12-3-7-14(8-4-12)24-10-9-15(17(24)26)22-13-5-1-11(2-6-13)16(25)23-27/h1-8,15,22,27H,9-10H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078689 (CHEMBL3415620) Show SMILES CS(=O)(=O)c1ccc(cc1)N1CCC(Nc2ccc(cc2)C(=O)NO)C1=O Show InChI InChI=1S/C18H19N3O5S/c1-27(25,26)15-8-6-14(7-9-15)21-11-10-16(18(21)23)19-13-4-2-12(3-5-13)17(22)20-24/h2-9,16,19,24H,10-11H2,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078757 (CHEMBL3415453) Show SMILES ONC(=O)c1ccc(NC2CCN(C2=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C17H16ClN3O3/c18-12-3-7-14(8-4-12)21-10-9-15(17(21)23)19-13-5-1-11(2-6-13)16(22)20-24/h1-8,15,19,24H,9-10H2,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078689 (CHEMBL3415620) Show SMILES CS(=O)(=O)c1ccc(cc1)N1CCC(Nc2ccc(cc2)C(=O)NO)C1=O Show InChI InChI=1S/C18H19N3O5S/c1-27(25,26)15-8-6-14(7-9-15)21-11-10-16(18(21)23)19-13-4-2-12(3-5-13)17(22)20-24/h2-9,16,19,24H,10-11H2,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078681 (CHEMBL3415456) Show SMILES ONC(=O)c1ccc(NC2CCN(C2=O)c2ccccc2Cl)cc1 Show InChI InChI=1S/C17H16ClN3O3/c18-13-3-1-2-4-15(13)21-10-9-14(17(21)23)19-12-7-5-11(6-8-12)16(22)20-24/h1-8,14,19,24H,9-10H2,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078687 (CHEMBL3415619) Show SMILES ONC(=O)c1ccc(NC2CCN(C2=O)c2ccc(Cl)c(Cl)c2)cc1 Show InChI InChI=1S/C17H15Cl2N3O3/c18-13-6-5-12(9-14(13)19)22-8-7-15(17(22)24)20-11-3-1-10(2-4-11)16(23)21-25/h1-6,9,15,20,25H,7-8H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078690 (CHEMBL3415621) Show SMILES ONC(=O)c1ccc(NC2CCN(C2=O)c2ccc(cc2)C#N)cc1 Show InChI InChI=1S/C18H16N4O3/c19-11-12-1-7-15(8-2-12)22-10-9-16(18(22)24)20-14-5-3-13(4-6-14)17(23)21-25/h1-8,16,20,25H,9-10H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078757 (CHEMBL3415453) Show SMILES ONC(=O)c1ccc(NC2CCN(C2=O)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C17H16ClN3O3/c18-12-3-7-14(8-4-12)21-10-9-15(17(21)23)19-13-5-1-11(2-6-13)16(22)20-24/h1-8,15,19,24H,9-10H2,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078748 (CHEMBL3415629) Show SMILES C[C@@]1(CCN(C1=O)c1ccc(Cl)cc1)Nc1ccc(cc1)C(=O)NO |r| Show InChI InChI=1S/C18H18ClN3O3/c1-18(20-14-6-2-12(3-7-14)16(23)21-25)10-11-22(17(18)24)15-8-4-13(19)5-9-15/h2-9,20,25H,10-11H2,1H3,(H,21,23)/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078680 (CHEMBL3415454) Show SMILES ONC(=O)c1ccc(NC2CCN(C2=O)c2cccc(Cl)c2)cc1 Show InChI InChI=1S/C17H16ClN3O3/c18-12-2-1-3-14(10-12)21-9-8-15(17(21)23)19-13-6-4-11(5-7-13)16(22)20-24/h1-7,10,15,19,24H,8-9H2,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078750 (CHEMBL3415446) Show SMILES ONC(=O)c1ccc(NC2CCN(C2=O)c2ccccc2)cc1 Show InChI InChI=1S/C17H17N3O3/c21-16(19-23)12-6-8-13(9-7-12)18-15-10-11-20(17(15)22)14-4-2-1-3-5-14/h1-9,15,18,23H,10-11H2,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078756 (CHEMBL3415452) Show SMILES ONC(=O)c1ccc(NC2CCN(CCc3ccccc3)C2=O)cc1 Show InChI InChI=1S/C19H21N3O3/c23-18(21-25)15-6-8-16(9-7-15)20-17-11-13-22(19(17)24)12-10-14-4-2-1-3-5-14/h1-9,17,20,25H,10-13H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078682 (CHEMBL3415618) Show SMILES ONC(=O)c1ccc(NC2CCN(C2=O)c2ccc(cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C18H16F3N3O3/c19-18(20,21)12-3-7-14(8-4-12)24-10-9-15(17(24)26)22-13-5-1-11(2-6-13)16(25)23-27/h1-8,15,22,27H,9-10H2,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078749 (CHEMBL3415630) Show SMILES C[C@]1(CCN(C1=O)c1ccc(Cl)cc1)Nc1ccc(cc1)C(=O)NO |r| Show InChI InChI=1S/C18H18ClN3O3/c1-18(20-14-6-2-12(3-7-14)16(23)21-25)10-11-22(17(18)24)15-8-4-13(19)5-9-15/h2-9,20,25H,10-11H2,1H3,(H,21,23)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078756 (CHEMBL3415452) Show SMILES ONC(=O)c1ccc(NC2CCN(CCc3ccccc3)C2=O)cc1 Show InChI InChI=1S/C19H21N3O3/c23-18(21-25)15-6-8-16(9-7-15)20-17-11-13-22(19(17)24)12-10-14-4-2-1-3-5-14/h1-9,17,20,25H,10-13H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078681 (CHEMBL3415456) Show SMILES ONC(=O)c1ccc(NC2CCN(C2=O)c2ccccc2Cl)cc1 Show InChI InChI=1S/C17H16ClN3O3/c18-13-3-1-2-4-15(13)21-10-9-14(17(21)23)19-12-7-5-11(6-8-12)16(22)20-24/h1-8,14,19,24H,9-10H2,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078750 (CHEMBL3415446) Show SMILES ONC(=O)c1ccc(NC2CCN(C2=O)c2ccccc2)cc1 Show InChI InChI=1S/C17H17N3O3/c21-16(19-23)12-6-8-13(9-7-12)18-15-10-11-20(17(15)22)14-4-2-1-3-5-14/h1-9,15,18,23H,10-11H2,(H,19,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078695 (CHEMBL3415627) Show SMILES CC1(CCN(C1=O)c1ccc(Cl)cc1)Nc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C18H18ClN3O3/c1-18(20-14-6-2-12(3-7-14)16(23)21-25)10-11-22(17(18)24)15-8-4-13(19)5-9-15/h2-9,20,25H,10-11H2,1H3,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	410	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078693 (CHEMBL3415626) Show SMILES CC1(CCN(C1=O)c1ccccc1)Nc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C18H19N3O3/c1-18(19-14-9-7-13(8-10-14)16(22)20-24)11-12-21(17(18)23)15-5-3-2-4-6-15/h2-10,19,24H,11-12H2,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM120996 (US8716285, 53) Show SMILES ONC(=O)c1ccc2NCC(Cc2c1)Nc1nccc(n1)-c1cccnc1 Show InChI InChI=1S/C19H18N6O2/c26-18(25-27)12-3-4-16-14(8-12)9-15(11-22-16)23-19-21-7-5-17(24-19)13-2-1-6-20-10-13/h1-8,10,15,22,27H,9,11H2,(H,25,26)(H,21,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	470	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078755 (CHEMBL3415451) Show SMILES ONC(=O)c1ccc(NC2CCN(Cc3ccccc3)C2=O)cc1 Show InChI InChI=1S/C18H19N3O3/c22-17(20-24)14-6-8-15(9-7-14)19-16-10-11-21(18(16)23)12-13-4-2-1-3-5-13/h1-9,16,19,24H,10-12H2,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	510	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078749 (CHEMBL3415630) Show SMILES C[C@]1(CCN(C1=O)c1ccc(Cl)cc1)Nc1ccc(cc1)C(=O)NO |r| Show InChI InChI=1S/C18H18ClN3O3/c1-18(20-14-6-2-12(3-7-14)16(23)21-25)10-11-22(17(18)24)15-8-4-13(19)5-9-15/h2-9,20,25H,10-11H2,1H3,(H,21,23)/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078693 (CHEMBL3415626) Show SMILES CC1(CCN(C1=O)c1ccccc1)Nc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C18H19N3O3/c1-18(19-14-9-7-13(8-10-14)16(22)20-24)11-12-21(17(18)23)15-5-3-2-4-6-15/h2-10,19,24H,11-12H2,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	n/a	n/a	660	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair				3D Structure (crystal)
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078755 (CHEMBL3415451) Show SMILES ONC(=O)c1ccc(NC2CCN(Cc3ccccc3)C2=O)cc1 Show InChI InChI=1S/C18H19N3O3/c22-17(20-24)14-6-8-15(9-7-14)19-16-10-11-21(18(16)23)12-13-4-2-1-3-5-13/h1-9,16,19,24H,10-12H2,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	760	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078692 (CHEMBL3415625) Show SMILES ONC(=O)c1ccc(NC2CCN(C2)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C17H18ClN3O2/c18-13-3-7-16(8-4-13)21-10-9-15(11-21)19-14-5-1-12(2-6-14)17(22)20-23/h1-8,15,19,23H,9-11H2,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078692 (CHEMBL3415625) Show SMILES ONC(=O)c1ccc(NC2CCN(C2)c2ccc(Cl)cc2)cc1 Show InChI InChI=1S/C17H18ClN3O2/c18-13-3-7-16(8-4-13)21-10-9-15(11-21)19-14-5-1-12(2-6-14)17(22)20-23/h1-8,15,19,23H,9-11H2,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	860	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078753 (CHEMBL3415449) Show SMILES CNc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C8H10N2O2/c1-9-7-4-2-6(3-5-7)8(11)10-12/h2-5,9,12H,1H3,(H,10,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078691 (CHEMBL3415624) Show SMILES ONC(=O)c1ccc(NC2CCN(C2=O)c2ccc(Cl)cc2)c(Cl)c1 Show InChI InChI=1S/C17H15Cl2N3O3/c18-11-2-4-12(5-3-11)22-8-7-15(17(22)24)20-14-6-1-10(9-13(14)19)16(23)21-25/h1-6,9,15,20,25H,7-8H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.07E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078753 (CHEMBL3415449) Show SMILES CNc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C8H10N2O2/c1-9-7-4-2-6(3-5-7)8(11)10-12/h2-5,9,12H,1H3,(H,10,11)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078754 (CHEMBL3415450) Show SMILES ONC(=O)c1ccc(NC2CN(C(=O)C2)c2ccccc2)cc1 Show InChI InChI=1S/C17H17N3O3/c21-16-10-14(11-20(16)15-4-2-1-3-5-15)18-13-8-6-12(7-9-13)17(22)19-23/h1-9,14,18,23H,10-11H2,(H,19,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078752 (CHEMBL3415448) Show SMILES ONC(=O)c1ccc(OC2CCN(C2=O)c2ccccc2)cc1 Show InChI InChI=1S/C17H16N2O4/c20-16(18-22)12-6-8-14(9-7-12)23-15-10-11-19(17(15)21)13-4-2-1-3-5-13/h1-9,15,22H,10-11H2,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50078752 (CHEMBL3415448) Show SMILES ONC(=O)c1ccc(OC2CCN(C2=O)c2ccccc2)cc1 Show InChI InChI=1S/C17H16N2O4/c20-16(18-22)12-6-8-14(9-7-12)23-15-10-11-19(17(15)21)13-4-2-1-3-5-13/h1-9,15,22H,10-11H2,(H,18,20)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC6 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50078747 (CHEMBL3415628) Show SMILES CC1(CCN(C1=O)c1ccc2ncccc2c1)Nc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C21H20N4O3/c1-21(23-16-6-4-14(5-7-16)19(26)24-28)10-12-25(20(21)27)17-8-9-18-15(13-17)3-2-11-22-18/h2-9,11,13,23,28H,10,12H2,1H3,(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078754 (CHEMBL3415450) Show SMILES ONC(=O)c1ccc(NC2CN(C(=O)C2)c2ccccc2)cc1 Show InChI InChI=1S/C17H17N3O3/c21-16-10-14(11-20(16)15-4-2-1-3-5-15)18-13-8-6-12(7-9-13)17(22)19-23/h1-9,14,18,23H,10-11H2,(H,19,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.25E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50027662 (CHEMBL3338418) Show SMILES ONC(=O)c1ccc2CC[C@H](Cc2c1)Nc1nccc(n1)-c1cccnc1 |r| Show InChI InChI=1S/C20H19N5O2/c26-19(25-27)14-4-3-13-5-6-17(11-16(13)10-14)23-20-22-9-7-18(24-20)15-2-1-8-21-12-15/h1-4,7-10,12,17,27H,5-6,11H2,(H,25,26)(H,22,23,24)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 8 (Homo sapiens (Human))	BDBM50078751 (CHEMBL3415447) Show SMILES CN(C1CCN(C1=O)c1ccccc1)c1ccc(cc1)C(=O)NO Show InChI InChI=1S/C18H19N3O3/c1-20(14-9-7-13(8-10-14)17(22)19-24)16-11-12-21(18(16)23)15-5-3-2-4-6-15/h2-10,16,24H,11-12H2,1H3,(H,19,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC8 (unknown origin) using RHK(Ac)K(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM50078756 (CHEMBL3415452) Show SMILES ONC(=O)c1ccc(NC2CCN(CCc3ccccc3)C2=O)cc1 Show InChI InChI=1S/C19H21N3O3/c23-18(21-25)15-6-8-16(9-7-15)20-17-11-13-22(19(17)24)12-10-14-4-2-1-3-5-14/h1-9,17,20,25H,10-13H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
Roche Innovation Center Shanghai Curated by ChEMBL					Assay Description Inhibition of HDAC1 (unknown origin) using RHKK(Ac)AMC as substrate				J Med Chem 58: 2809-20 (2015) Article DOI: 10.1021/jm502011f BindingDB Entry DOI: 10.7270/Q2B56MF0
					More data for this Ligand-Target Pair

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