Compile Data Set for Download or QSAR

Found 85 hits Enz. Inhib. hit(s) with all data for entry = 50016953   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175717 (4-(1-benzyl-1H-imidazol-2-yl)-N,4-diphenylpiperidi...) Show SMILES O=S(=O)(Nc1ccccc1)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H28N4O2S/c32-34(33,29-25-14-8-3-9-15-25)31-19-16-27(17-20-31,24-12-6-2-7-13-24)26-28-18-21-30(26)22-23-10-4-1-5-11-23/h1-15,18,21,29H,16-17,19-20,22H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175723 (4-(1-benzyl-1H-imidazol-2-yl)-N-methyl-N,4-dipheny...) Show SMILES CN(C(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H30N4O/c1-31(26-15-9-4-10-16-26)28(34)32-20-17-29(18-21-32,25-13-7-3-8-14-25)27-30-19-22-33(27)23-24-11-5-2-6-12-24/h2-16,19,22H,17-18,20-21,23H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175719 (2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...) Show SMILES C(c1ccccc1)n1ccnc1C1(CCN(CC1)c1ncccn1)c1ccccc1 Show InChI InChI=1S/C25H25N5/c1-3-8-21(9-4-1)20-30-19-16-26-23(30)25(22-10-5-2-6-11-22)12-17-29(18-13-25)24-27-14-7-15-28-24/h1-11,14-16,19H,12-13,17-18,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175733 (4-(1-benzyl-1H-imidazol-2-yl)-N-(2-fluorophenyl)-4...) Show SMILES Fc1ccccc1NC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H27FN4O/c29-24-13-7-8-14-25(24)31-27(34)32-18-15-28(16-19-32,23-11-5-2-6-12-23)26-30-17-20-33(26)21-22-9-3-1-4-10-22/h1-14,17,20H,15-16,18-19,21H2,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175738 (4-(1-benzyl-1H-imidazol-2-yl)-N-(3-fluorophenyl)-4...) Show SMILES Fc1cccc(NC(=O)N2CCC(CC2)(c2nccn2Cc2ccccc2)c2ccccc2)c1 Show InChI InChI=1S/C28H27FN4O/c29-24-12-7-13-25(20-24)31-27(34)32-17-14-28(15-18-32,23-10-5-2-6-11-23)26-30-16-19-33(26)21-22-8-3-1-4-9-22/h1-13,16,19-20H,14-15,17-18,21H2,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175737 (4-(1-benzyl-1H-imidazol-2-yl)-N-(2-methoxyphenyl)-...) Show SMILES COc1ccccc1NC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H30N4O2/c1-35-26-15-9-8-14-25(26)31-28(34)32-19-16-29(17-20-32,24-12-6-3-7-13-24)27-30-18-21-33(27)22-23-10-4-2-5-11-23/h2-15,18,21H,16-17,19-20,22H2,1H3,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175731 (4-(1-benzyl-1H-imidazol-2-yl)-N-ethyl-4-phenylpipe...) Show SMILES CCNC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H28N4O/c1-2-25-23(29)27-16-13-24(14-17-27,21-11-7-4-8-12-21)22-26-15-18-28(22)19-20-9-5-3-6-10-20/h3-12,15,18H,2,13-14,16-17,19H2,1H3,(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	39	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50175722 (2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...) Show SMILES Cn1c(nc2ccccc12)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H29N5/c1-32-26-15-9-8-14-25(26)31-28(32)33-19-16-29(17-20-33,24-12-6-3-7-13-24)27-30-18-21-34(27)22-23-10-4-2-5-11-23/h2-15,18,21H,16-17,19-20,22H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175727 (CHEMBL200067 | N,4-diphenyl-4-(1-(1-phenylethyl)-1...) Show SMILES CC(c1ccccc1)n1ccnc1C1(CCN(CC1)C(=O)Nc1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H30N4O/c1-23(24-11-5-2-6-12-24)33-22-19-30-27(33)29(25-13-7-3-8-14-25)17-20-32(21-18-29)28(34)31-26-15-9-4-10-16-26/h2-16,19,22-23H,17-18,20-21H2,1H3,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175728 (4-(1-benzyl-1H-imidazol-2-yl)-N-(4-methoxyphenyl)-...) Show SMILES COc1ccc(NC(=O)N2CCC(CC2)(c2nccn2Cc2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C29H30N4O2/c1-35-26-14-12-25(13-15-26)31-28(34)32-19-16-29(17-20-32,24-10-6-3-7-11-24)27-30-18-21-33(27)22-23-8-4-2-5-9-23/h2-15,18,21H,16-17,19-20,22H2,1H3,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175740 (4-(1-benzyl-1H-imidazol-2-yl)-N-(3-methoxyphenyl)-...) Show SMILES COc1cccc(NC(=O)N2CCC(CC2)(c2nccn2Cc2ccccc2)c2ccccc2)c1 Show InChI InChI=1S/C29H30N4O2/c1-35-26-14-8-13-25(21-26)31-28(34)32-18-15-29(16-19-32,24-11-6-3-7-12-24)27-30-17-20-33(27)22-23-9-4-2-5-10-23/h2-14,17,20-21H,15-16,18-19,22H2,1H3,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50175730 (CHEMBL197917 | N,4-diphenyl-4-(1-(pyridin-2-ylmeth...) Show SMILES O=C(Nc1ccccc1)N1CCC(CC1)(c1nccn1Cc1ccccn1)c1ccccc1 Show InChI InChI=1S/C27H27N5O/c33-26(30-23-11-5-2-6-12-23)31-18-14-27(15-19-31,22-9-3-1-4-10-22)25-29-17-20-32(25)21-24-13-7-8-16-28-24/h1-13,16-17,20H,14-15,18-19,21H2,(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175739 (4-(1-benzyl-1H-imidazol-2-yl)-1-(methylsulfonyl)-4...) Show SMILES CS(=O)(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C22H25N3O2S/c1-28(26,27)25-15-12-22(13-16-25,20-10-6-3-7-11-20)21-23-14-17-24(21)18-19-8-4-2-5-9-19/h2-11,14,17H,12-13,15-16,18H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175735 (4-(1-(2-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...) Show SMILES Fc1ccccc1Cn1ccnc1C1(CCN(CC1)C(=O)Nc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H27FN4O/c29-25-14-8-7-9-22(25)21-33-20-17-30-26(33)28(23-10-3-1-4-11-23)15-18-32(19-16-28)27(34)31-24-12-5-2-6-13-24/h1-14,17,20H,15-16,18-19,21H2,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175725 (2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...) Show SMILES C(c1ccccc1)n1ccnc1C1(CCN(CC1)c1nc2ccccc2s1)c1ccccc1 Show InChI InChI=1S/C28H26N4S/c1-3-9-22(10-4-1)21-32-20-17-29-26(32)28(23-11-5-2-6-12-23)15-18-31(19-16-28)27-30-24-13-7-8-14-25(24)33-27/h1-14,17,20H,15-16,18-19,21H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	73	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175734 (4-(1-benzyl-1H-imidazol-2-yl)-4-phenyl-1-(thiazol-...) Show SMILES C(c1ccccc1)n1ccnc1C1(CCN(CC1)c1nccs1)c1ccccc1 Show InChI InChI=1S/C24H24N4S/c1-3-7-20(8-4-1)19-28-17-13-25-22(28)24(21-9-5-2-6-10-21)11-15-27(16-12-24)23-26-14-18-29-23/h1-10,13-14,17-18H,11-12,15-16,19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175741 (4-phenyl-4-[1H-imidazol-2-yl]-piperidine | CHEMBL3...) Show SMILES O=C(Nc1ccccc1)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H28N4O/c33-27(30-25-14-8-3-9-15-25)31-19-16-28(17-20-31,24-12-6-2-7-13-24)26-29-18-21-32(26)22-23-10-4-1-5-11-23/h1-15,18,21H,16-17,19-20,22H2,(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	81	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175729 (4-(1-benzyl-1H-imidazol-2-yl)-N-(4-fluorophenyl)-4...) Show SMILES Fc1ccc(NC(=O)N2CCC(CC2)(c2nccn2Cc2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C28H27FN4O/c29-24-11-13-25(14-12-24)31-27(34)32-18-15-28(16-19-32,23-9-5-2-6-10-23)26-30-17-20-33(26)21-22-7-3-1-4-8-22/h1-14,17,20H,15-16,18-19,21H2,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	97	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175720 (4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidine-1...) Show SMILES NC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C22H24N4O/c23-21(27)25-14-11-22(12-15-25,19-9-5-2-6-10-19)20-24-13-16-26(20)17-18-7-3-1-4-8-18/h1-10,13,16H,11-12,14-15,17H2,(H2,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175721 (4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidine-1...) Show SMILES NS(=O)(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C21H24N4O2S/c22-28(26,27)25-14-11-21(12-15-25,19-9-5-2-6-10-19)20-23-13-16-24(20)17-18-7-3-1-4-8-18/h1-10,13,16H,11-12,14-15,17H2,(H2,22,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	106	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50175735 (4-(1-(2-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...) Show SMILES Fc1ccccc1Cn1ccnc1C1(CCN(CC1)C(=O)Nc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H27FN4O/c29-25-14-8-7-9-22(25)21-33-20-17-30-26(33)28(23-10-3-1-4-11-23)15-18-32(19-16-28)27(34)31-24-12-5-2-6-13-24/h1-14,17,20H,15-16,18-19,21H2,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	116	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50175741 (4-phenyl-4-[1H-imidazol-2-yl]-piperidine | CHEMBL3...) Show SMILES O=C(Nc1ccccc1)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H28N4O/c33-27(30-25-14-8-3-9-15-25)31-19-16-28(17-20-31,24-12-6-2-7-13-24)26-29-18-21-32(26)22-23-10-4-1-5-11-23/h1-15,18,21H,16-17,19-20,22H2,(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175724 (4-(1-(3-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...) Show SMILES Fc1cccc(Cn2ccnc2C2(CCN(CC2)C(=O)Nc2ccccc2)c2ccccc2)c1 Show InChI InChI=1S/C28H27FN4O/c29-24-11-7-8-22(20-24)21-33-19-16-30-26(33)28(23-9-3-1-4-10-23)14-17-32(18-15-28)27(34)31-25-12-5-2-6-13-25/h1-13,16,19-20H,14-15,17-18,21H2,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	128	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175722 (2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...) Show SMILES Cn1c(nc2ccccc12)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H29N5/c1-32-26-15-9-8-14-25(26)31-28(32)33-19-16-29(17-20-33,24-12-6-3-7-13-24)27-30-18-21-34(27)22-23-10-4-2-5-11-23/h2-15,18,21H,16-17,19-20,22H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	138	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50175729 (4-(1-benzyl-1H-imidazol-2-yl)-N-(4-fluorophenyl)-4...) Show SMILES Fc1ccc(NC(=O)N2CCC(CC2)(c2nccn2Cc2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C28H27FN4O/c29-24-11-13-25(14-12-24)31-27(34)32-18-15-28(16-19-32,23-9-5-2-6-10-23)26-30-17-20-33(26)21-22-7-3-1-4-8-22/h1-14,17,20H,15-16,18-19,21H2,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	148	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50175740 (4-(1-benzyl-1H-imidazol-2-yl)-N-(3-methoxyphenyl)-...) Show SMILES COc1cccc(NC(=O)N2CCC(CC2)(c2nccn2Cc2ccccc2)c2ccccc2)c1 Show InChI InChI=1S/C29H30N4O2/c1-35-26-14-8-13-25(21-26)31-28(34)32-18-15-29(16-19-32,24-11-6-3-7-12-24)27-30-17-20-33(27)22-23-9-4-2-5-10-23/h2-14,17,20-21H,15-16,18-19,22H2,1H3,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	152	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175718 ((4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1...) Show SMILES CN1CCN(CC1)C(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H33N5O/c1-29-18-20-31(21-19-29)26(33)30-15-12-27(13-16-30,24-10-6-3-7-11-24)25-28-14-17-32(25)22-23-8-4-2-5-9-23/h2-11,14,17H,12-13,15-16,18-22H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	161	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175732 (4-(1-(4-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...) Show SMILES Fc1ccc(Cn2ccnc2C2(CCN(CC2)C(=O)Nc2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C28H27FN4O/c29-24-13-11-22(12-14-24)21-33-20-17-30-26(33)28(23-7-3-1-4-8-23)15-18-32(19-16-28)27(34)31-25-9-5-2-6-10-25/h1-14,17,20H,15-16,18-19,21H2,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	203	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175716 (4-(1-(3-methoxybenzyl)-1H-imidazol-2-yl)-N,4-diphe...) Show SMILES COc1cccc(Cn2ccnc2C2(CCN(CC2)C(=O)Nc2ccccc2)c2ccccc2)c1 Show InChI InChI=1S/C29H30N4O2/c1-35-26-14-8-9-23(21-26)22-33-20-17-30-27(33)29(24-10-4-2-5-11-24)15-18-32(19-16-29)28(34)31-25-12-6-3-7-13-25/h2-14,17,20-21H,15-16,18-19,22H2,1H3,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	217	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50175722 (2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...) Show SMILES Cn1c(nc2ccccc12)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H29N5/c1-32-26-15-9-8-14-25(26)31-28(32)33-19-16-29(17-20-33,24-12-6-3-7-13-24)27-30-18-21-34(27)22-23-10-4-2-5-11-23/h2-15,18,21H,16-17,19-20,22H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	235	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from cloned human mu opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50175731 (4-(1-benzyl-1H-imidazol-2-yl)-N-ethyl-4-phenylpipe...) Show SMILES CCNC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C24H28N4O/c1-2-25-23(29)27-16-13-24(14-17-27,21-11-7-4-8-12-21)22-26-15-18-28(22)19-20-9-5-3-6-10-20/h3-12,15,18H,2,13-14,16-17,19H2,1H3,(H,25,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	242	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50175733 (4-(1-benzyl-1H-imidazol-2-yl)-N-(2-fluorophenyl)-4...) Show SMILES Fc1ccccc1NC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H27FN4O/c29-24-13-7-8-14-25(24)31-27(34)32-18-15-28(16-19-32,23-11-5-2-6-12-23)26-30-17-20-33(26)21-22-9-3-1-4-10-22/h1-14,17,20H,15-16,18-19,21H2,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	318	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50175720 (4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidine-1...) Show SMILES NC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C22H24N4O/c23-21(27)25-14-11-22(12-15-25,19-9-5-2-6-10-19)20-24-13-16-26(20)17-18-7-3-1-4-8-18/h1-10,13,16H,11-12,14-15,17H2,(H2,23,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	334	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50175717 (4-(1-benzyl-1H-imidazol-2-yl)-N,4-diphenylpiperidi...) Show SMILES O=S(=O)(Nc1ccccc1)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H28N4O2S/c32-34(33,29-25-14-8-3-9-15-25)31-19-16-27(17-20-31,24-12-6-2-7-13-24)26-28-18-21-30(26)22-23-10-4-1-5-11-23/h1-15,18,21,29H,16-17,19-20,22H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	346	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50175723 (4-(1-benzyl-1H-imidazol-2-yl)-N-methyl-N,4-dipheny...) Show SMILES CN(C(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H30N4O/c1-31(26-15-9-4-10-16-26)28(34)32-20-17-29(18-21-32,25-13-7-3-8-14-25)27-30-19-22-33(27)23-24-11-5-2-6-12-24/h2-16,19,22H,17-18,20-21,23H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	397	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50175735 (4-(1-(2-fluorobenzyl)-1H-imidazol-2-yl)-N,4-diphen...) Show SMILES Fc1ccccc1Cn1ccnc1C1(CCN(CC1)C(=O)Nc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H27FN4O/c29-25-14-8-7-9-22(25)21-33-20-17-30-26(33)28(23-10-3-1-4-11-23)15-18-32(19-16-28)27(34)31-24-12-5-2-6-13-24/h1-14,17,20H,15-16,18-19,21H2,(H,31,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	428	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from cloned human mu opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50175728 (4-(1-benzyl-1H-imidazol-2-yl)-N-(4-methoxyphenyl)-...) Show SMILES COc1ccc(NC(=O)N2CCC(CC2)(c2nccn2Cc2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C29H30N4O2/c1-35-26-14-12-25(13-15-26)31-28(34)32-19-16-29(17-20-32,24-10-6-3-7-11-24)27-30-18-21-33(27)22-23-8-4-2-5-9-23/h2-15,18,21H,16-17,19-20,22H2,1H3,(H,31,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>465	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from cloned human mu opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM50175726 (4-(1H-imidazol-2-yl)-N,4-diphenylpiperidine-1-carb...) Show SMILES O=C(Nc1ccccc1)N1CCC(CC1)(c1ncc[nH]1)c1ccccc1 Show InChI InChI=1S/C21H22N4O/c26-20(24-18-9-5-2-6-10-18)25-15-11-21(12-16-25,19-22-13-14-23-19)17-7-3-1-4-8-17/h1-10,13-14H,11-12,15-16H2,(H,22,23)(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>465	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DPDPE from cloned human delta opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50175727 (CHEMBL200067 | N,4-diphenyl-4-(1-(1-phenylethyl)-1...) Show SMILES CC(c1ccccc1)n1ccnc1C1(CCN(CC1)C(=O)Nc1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H30N4O/c1-23(24-11-5-2-6-12-24)33-22-19-30-27(33)29(25-13-7-3-8-14-25)17-20-32(21-18-29)28(34)31-26-15-9-4-10-16-26/h2-16,19,22-23H,17-18,20-21H2,1H3,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>465	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50175726 (4-(1H-imidazol-2-yl)-N,4-diphenylpiperidine-1-carb...) Show SMILES O=C(Nc1ccccc1)N1CCC(CC1)(c1ncc[nH]1)c1ccccc1 Show InChI InChI=1S/C21H22N4O/c26-20(24-18-9-5-2-6-10-18)25-15-11-21(12-16-25,19-22-13-14-23-19)17-7-3-1-4-8-17/h1-10,13-14H,11-12,15-16H2,(H,22,23)(H,24,26)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>465	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from cloned human mu opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50175741 (4-phenyl-4-[1H-imidazol-2-yl]-piperidine | CHEMBL3...) Show SMILES O=C(Nc1ccccc1)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H28N4O/c33-27(30-25-14-8-3-9-15-25)31-19-16-28(17-20-31,24-12-6-2-7-13-24)26-29-18-21-32(26)22-23-10-4-1-5-11-23/h1-15,18,21H,16-17,19-20,22H2,(H,30,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>465	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from cloned human mu opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50175727 (CHEMBL200067 | N,4-diphenyl-4-(1-(1-phenylethyl)-1...) Show SMILES CC(c1ccccc1)n1ccnc1C1(CCN(CC1)C(=O)Nc1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H30N4O/c1-23(24-11-5-2-6-12-24)33-22-19-30-27(33)29(25-13-7-3-8-14-25)17-20-32(21-18-29)28(34)31-26-15-9-4-10-16-26/h2-16,19,22-23H,17-18,20-21H2,1H3,(H,31,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	497	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from cloned human mu opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50175719 (2-(4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin...) Show SMILES C(c1ccccc1)n1ccnc1C1(CCN(CC1)c1ncccn1)c1ccccc1 Show InChI InChI=1S/C25H25N5/c1-3-8-21(9-4-1)20-30-19-16-26-23(30)25(22-10-5-2-6-11-22)12-17-29(18-13-25)24-27-14-7-15-28-24/h1-11,14-16,19H,12-13,17-18,20H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	505	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50175737 (4-(1-benzyl-1H-imidazol-2-yl)-N-(2-methoxyphenyl)-...) Show SMILES COc1ccccc1NC(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C29H30N4O2/c1-35-26-15-9-8-14-25(26)31-28(34)32-19-16-29(17-20-32,24-12-6-3-7-13-24)27-30-18-21-33(27)22-23-10-4-2-5-11-23/h2-15,18,21H,16-17,19-20,22H2,1H3,(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	782	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50175718 ((4-(1-benzyl-1H-imidazol-2-yl)-4-phenylpiperidin-1...) Show SMILES CN1CCN(CC1)C(=O)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H33N5O/c1-29-18-20-31(21-19-29)26(33)30-15-12-27(13-16-30,24-10-6-3-7-11-24)25-28-14-17-32(25)22-23-8-4-2-5-9-23/h2-11,14,17H,12-13,15-16,18-22H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	858	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50175717 (4-(1-benzyl-1H-imidazol-2-yl)-N,4-diphenylpiperidi...) Show SMILES O=S(=O)(Nc1ccccc1)N1CCC(CC1)(c1nccn1Cc1ccccc1)c1ccccc1 Show InChI InChI=1S/C27H28N4O2S/c32-34(33,29-25-14-8-3-9-15-25)31-19-16-27(17-20-31,24-12-6-2-7-13-24)26-28-18-21-30(26)22-23-10-4-1-5-11-23/h1-15,18,21,29H,16-17,19-20,22H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	980	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from cloned human mu opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50175736 (4-(1-benzoyl-1H-imidazol-2-yl)-N,4-diphenylpiperid...) Show SMILES O=C(Nc1ccccc1)N1CCC(CC1)(c1nccn1C(=O)c1ccccc1)c1ccccc1 Show InChI InChI=1S/C28H26N4O2/c33-25(22-10-4-1-5-11-22)32-21-18-29-26(32)28(23-12-6-2-7-13-23)16-19-31(20-17-28)27(34)30-24-14-8-3-9-15-24/h1-15,18,21H,16-17,19-20H2,(H,30,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.19E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]U-69593 from cloned human kappa opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50175729 (4-(1-benzyl-1H-imidazol-2-yl)-N-(4-fluorophenyl)-4...) Show SMILES Fc1ccc(NC(=O)N2CCC(CC2)(c2nccn2Cc2ccccc2)c2ccccc2)cc1 Show InChI InChI=1S/C28H27FN4O/c29-24-11-13-25(14-12-24)31-27(34)32-18-15-28(16-19-32,23-9-5-2-6-10-23)26-30-17-20-33(26)21-22-7-3-1-4-8-22/h1-14,17,20H,15-16,18-19,21H2,(H,31,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.21E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from cloned human mu opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50175740 (4-(1-benzyl-1H-imidazol-2-yl)-N-(3-methoxyphenyl)-...) Show SMILES COc1cccc(NC(=O)N2CCC(CC2)(c2nccn2Cc2ccccc2)c2ccccc2)c1 Show InChI InChI=1S/C29H30N4O2/c1-35-26-14-8-13-25(21-26)31-28(34)32-18-15-29(16-19-32,24-11-6-3-7-12-24)27-30-17-20-33(27)22-23-9-4-2-5-10-23/h2-14,17,20-21H,15-16,18-19,22H2,1H3,(H,31,34)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.39E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from cloned human mu opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50175730 (CHEMBL197917 | N,4-diphenyl-4-(1-(pyridin-2-ylmeth...) Show SMILES O=C(Nc1ccccc1)N1CCC(CC1)(c1nccn1Cc1ccccn1)c1ccccc1 Show InChI InChI=1S/C27H27N5O/c33-26(30-23-11-5-2-6-12-23)31-18-14-27(15-19-31,22-9-3-1-4-10-22)25-29-17-20-32(25)21-24-13-7-8-16-28-24/h1-13,16-17,20H,14-15,18-19,21H2,(H,30,33)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.42E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]DAMGO from cloned human mu opioid receptor				Bioorg Med Chem Lett 16: 146-9 (2005) Article DOI: 10.1016/j.bmcl.2005.09.025 BindingDB Entry DOI: 10.7270/Q2ZK5G70
					More data for this Ligand-Target Pair

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