Compile Data Set for Download or QSAR

Found 90 hits Enz. Inhib. hit(s) with all data for entry = 50017085   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177232 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCCCn3ccnc3)C(=O)NC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C32H39BrClN7O2/c33-24-17-23-8-7-22-18-25(34)9-10-27(22)30(29(23)37-19-24)40-15-16-41(32(43)38-26-5-2-1-3-6-26)28(20-40)31(42)36-11-4-13-39-14-12-35-21-39/h9-10,12,14,17-19,21,26,28,30H,1-8,11,13,15-16,20H2,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against Farnesyltransferase quantified by modified SPA assay with improved sensitivity				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177232 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCCCn3ccnc3)C(=O)NC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C32H39BrClN7O2/c33-24-17-23-8-7-22-18-25(34)9-10-27(22)30(29(23)37-19-24)40-15-16-41(32(43)38-26-5-2-1-3-6-26)28(20-40)31(42)36-11-4-13-39-14-12-35-21-39/h9-10,12,14,17-19,21,26,28,30H,1-8,11,13,15-16,20H2,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against Ha-Ras processing in COS7 cells				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177232 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCCCn3ccnc3)C(=O)NC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C32H39BrClN7O2/c33-24-17-23-8-7-22-18-25(34)9-10-27(22)30(29(23)37-19-24)40-15-16-41(32(43)38-26-5-2-1-3-6-26)28(20-40)31(42)36-11-4-13-39-14-12-35-21-39/h9-10,12,14,17-19,21,26,28,30H,1-8,11,13,15-16,20H2,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177232 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCCCn3ccnc3)C(=O)NC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C32H39BrClN7O2/c33-24-17-23-8-7-22-18-25(34)9-10-27(22)30(29(23)37-19-24)40-15-16-41(32(43)38-26-5-2-1-3-6-26)28(20-40)31(42)36-11-4-13-39-14-12-35-21-39/h9-10,12,14,17-19,21,26,28,30H,1-8,11,13,15-16,20H2,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against Ha-Ras processing in COS7 cells				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177232 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCCCn3ccnc3)C(=O)NC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C32H39BrClN7O2/c33-24-17-23-8-7-22-18-25(34)9-10-27(22)30(29(23)37-19-24)40-15-16-41(32(43)38-26-5-2-1-3-6-26)28(20-40)31(42)36-11-4-13-39-14-12-35-21-39/h9-10,12,14,17-19,21,26,28,30H,1-8,11,13,15-16,20H2,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against Ha-Ras processing in COS7 cells				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177232 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCCCn3ccnc3)C(=O)NC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C32H39BrClN7O2/c33-24-17-23-8-7-22-18-25(34)9-10-27(22)30(29(23)37-19-24)40-15-16-41(32(43)38-26-5-2-1-3-6-26)28(20-40)31(42)36-11-4-13-39-14-12-35-21-39/h9-10,12,14,17-19,21,26,28,30H,1-8,11,13,15-16,20H2,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177232 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCCCn3ccnc3)C(=O)NC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C32H39BrClN7O2/c33-24-17-23-8-7-22-18-25(34)9-10-27(22)30(29(23)37-19-24)40-15-16-41(32(43)38-26-5-2-1-3-6-26)28(20-40)31(42)36-11-4-13-39-14-12-35-21-39/h9-10,12,14,17-19,21,26,28,30H,1-8,11,13,15-16,20H2,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Mus musculus)	BDBM50177232 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCCCn3ccnc3)C(=O)NC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C32H39BrClN7O2/c33-24-17-23-8-7-22-18-25(34)9-10-27(22)30(29(23)37-19-24)40-15-16-41(32(43)38-26-5-2-1-3-6-26)28(20-40)31(42)36-11-4-13-39-14-12-35-21-39/h9-10,12,14,17-19,21,26,28,30H,1-8,11,13,15-16,20H2,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Anchorage-independent growth of transformed NIH3T3 cells in soft agar				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Protein farnesyltransferase subunit beta/geranylgeranyltransferase type-1 subunit alpha (Mus musculus)	BDBM50177232 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCCCn3ccnc3)C(=O)NC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C32H39BrClN7O2/c33-24-17-23-8-7-22-18-25(34)9-10-27(22)30(29(23)37-19-24)40-15-16-41(32(43)38-26-5-2-1-3-6-26)28(20-40)31(42)36-11-4-13-39-14-12-35-21-39/h9-10,12,14,17-19,21,26,28,30H,1-8,11,13,15-16,20H2,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Anchorage-independent growth of transformed NIH3T3 cells in soft agar				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177263 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCc3cccnc3)C(=O)NC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C32H36BrClN6O2/c33-24-15-23-9-8-22-16-25(34)10-11-27(22)30(29(23)36-19-24)39-13-14-40(32(42)38-26-6-2-1-3-7-26)28(20-39)31(41)37-18-21-5-4-12-35-17-21/h4-5,10-12,15-17,19,26,28,30H,1-3,6-9,13-14,18,20H2,(H,37,41)(H,38,42)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177231 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES CCCCC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C30H33BrClN5O2/c1-2-3-6-27(38)37-13-12-36(19-26(37)30(39)35-17-20-5-4-11-33-16-20)29-25-10-9-24(32)15-21(25)7-8-22-14-23(31)18-34-28(22)29/h4-5,9-11,14-16,18,26,29H,2-3,6-8,12-13,17,19H2,1H3,(H,35,39)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177258 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCCc3cnc[nH]3)C(=O)NC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C31H37BrClN7O2/c32-22-14-21-7-6-20-15-23(33)8-9-26(20)29(28(21)36-16-22)39-12-13-40(31(42)38-24-4-2-1-3-5-24)27(18-39)30(41)35-11-10-25-17-34-19-37-25/h8-9,14-17,19,24,27,29H,1-7,10-13,18H2,(H,34,37)(H,35,41)(H,38,42)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177268 (5-{4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]c...) Show SMILES OC(=O)CCCC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C30H31BrClN5O4/c31-22-13-21-7-6-20-14-23(32)8-9-24(20)29(28(21)34-17-22)36-11-12-37(26(38)4-1-5-27(39)40)25(18-36)30(41)35-16-19-3-2-10-33-15-19/h2-3,8-10,13-15,17,25,29H,1,4-7,11-12,16,18H2,(H,35,41)(H,39,40)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177265 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Cn1cncc1CCNC(=O)C1CN(CCN1C(=O)NC1CCCCC1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C32H39BrClN7O2/c1-39-20-35-18-26(39)11-12-36-31(42)28-19-40(13-14-41(28)32(43)38-25-5-3-2-4-6-25)30-27-10-9-24(34)16-21(27)7-8-22-15-23(33)17-37-29(22)30/h9-10,15-18,20,25,28,30H,2-8,11-14,19H2,1H3,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177239 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES CC(C)CC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C30H33BrClN5O2/c1-19(2)12-27(38)37-11-10-36(18-26(37)30(39)35-16-20-4-3-9-33-15-20)29-25-8-7-24(32)14-21(25)5-6-22-13-23(31)17-34-28(22)29/h3-4,7-9,13-15,17,19,26,29H,5-6,10-12,16,18H2,1-2H3,(H,35,39)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177255 (6-{4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]c...) Show SMILES COC(=O)CCCCC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C32H35BrClN5O4/c1-43-29(41)7-3-2-6-28(40)39-14-13-38(20-27(39)32(42)37-18-21-5-4-12-35-17-21)31-26-11-10-25(34)16-22(26)8-9-23-15-24(33)19-36-30(23)31/h4-5,10-12,15-17,19,27,31H,2-3,6-9,13-14,18,20H2,1H3,(H,37,42)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177257 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES CCCCCC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C31H35BrClN5O2/c1-2-3-4-7-28(39)38-14-13-37(20-27(38)31(40)36-18-21-6-5-12-34-17-21)30-26-11-10-25(33)16-22(26)8-9-23-15-24(32)19-35-29(23)30/h5-6,10-12,15-17,19,27,30H,2-4,7-9,13-14,18,20H2,1H3,(H,36,40)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177241 (4-(3-bromo-8-chloro-6,11-dihydro-5-benzo[5,6]cyclo...) Show SMILES CC(C)CNC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C30H34BrClN6O2/c1-19(2)14-36-30(40)38-11-10-37(18-26(38)29(39)35-16-20-4-3-9-33-15-20)28-25-8-7-24(32)13-21(25)5-6-22-12-23(31)17-34-27(22)28/h3-4,7-9,12-13,15,17,19,26,28H,5-6,10-11,14,16,18H2,1-2H3,(H,35,39)(H,36,40)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177267 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES CC(=O)CCCCC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C32H35BrClN5O3/c1-21(40)5-2-3-7-29(41)39-14-13-38(20-28(39)32(42)37-18-22-6-4-12-35-17-22)31-27-11-10-26(34)16-23(27)8-9-24-15-25(33)19-36-30(24)31/h4,6,10-12,15-17,19,28,31H,2-3,5,7-9,13-14,18,20H2,1H3,(H,37,42)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177250 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES CC(=O)CCCC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C31H33BrClN5O3/c1-20(39)4-2-6-28(40)38-13-12-37(19-27(38)31(41)36-17-21-5-3-11-34-16-21)30-26-10-9-25(33)15-22(26)7-8-23-14-24(32)18-35-29(23)30/h3,5,9-11,14-16,18,27,30H,2,4,6-8,12-13,17,19H2,1H3,(H,36,41)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.40	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177263 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCc3cccnc3)C(=O)NC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C32H36BrClN6O2/c33-24-15-23-9-8-22-16-25(34)10-11-27(22)30(29(23)36-19-24)39-13-14-40(32(42)38-26-6-2-1-3-7-26)28(20-39)31(41)37-18-21-5-4-12-35-17-21/h4-5,10-12,15-17,19,26,28,30H,1-3,6-9,13-14,18,20H2,(H,37,41)(H,38,42)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.60	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against Ha-Ras processing in COS7 cells				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177243 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCc3cccnc3)C(=O)NC3CCCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C33H38BrClN6O2/c34-25-16-24-10-9-23-17-26(35)11-12-28(23)31(30(24)37-20-25)40-14-15-41(33(43)39-27-7-3-1-2-4-8-27)29(21-40)32(42)38-19-22-6-5-13-36-18-22/h5-6,11-13,16-18,20,27,29,31H,1-4,7-10,14-15,19,21H2,(H,38,42)(H,39,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177235 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES CCCCNC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C30H34BrClN6O2/c1-2-3-11-34-30(40)38-13-12-37(19-26(38)29(39)36-17-20-5-4-10-33-16-20)28-25-9-8-24(32)15-21(25)6-7-22-14-23(31)18-35-27(22)28/h4-5,8-10,14-16,18,26,28H,2-3,6-7,11-13,17,19H2,1H3,(H,34,40)(H,36,39)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177252 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCCCc3cnc[nH]3)C(=O)NC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C32H39BrClN7O2/c33-23-15-22-9-8-21-16-24(34)10-11-27(21)30(29(22)37-17-23)40-13-14-41(32(43)39-25-5-2-1-3-6-25)28(19-40)31(42)36-12-4-7-26-18-35-20-38-26/h10-11,15-18,20,25,28,30H,1-9,12-14,19H2,(H,35,38)(H,36,42)(H,39,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against Ha-Ras processing in COS7 cells				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177234 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCc3cccnc3)C(=O)NCC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C33H38BrClN6O2/c34-26-15-25-9-8-24-16-27(35)10-11-28(24)31(30(25)37-20-26)40-13-14-41(33(43)39-18-22-5-2-1-3-6-22)29(21-40)32(42)38-19-23-7-4-12-36-17-23/h4,7,10-12,15-17,20,22,29,31H,1-3,5-6,8-9,13-14,18-19,21H2,(H,38,42)(H,39,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177266 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES CN(C)C(=O)CCC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C31H34BrClN6O3/c1-37(2)27(40)9-10-28(41)39-13-12-38(19-26(39)31(42)36-17-20-4-3-11-34-16-20)30-25-8-7-24(33)15-21(25)5-6-22-14-23(32)18-35-29(22)30/h3-4,7-8,11,14-16,18,26,30H,5-6,9-10,12-13,17,19H2,1-2H3,(H,36,42)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against Ha-Ras processing in COS7 cells				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177229 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES CC(=O)CCC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C30H31BrClN5O3/c1-19(38)4-9-27(39)37-12-11-36(18-26(37)30(40)35-16-20-3-2-10-33-15-20)29-25-8-7-24(32)14-21(25)5-6-22-13-23(31)17-34-28(22)29/h2-3,7-8,10,13-15,17,26,29H,4-6,9,11-12,16,18H2,1H3,(H,35,40)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177236 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCc3cccnc3)C(=O)C3CCCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C33H37BrClN5O2/c34-26-16-25-10-9-24-17-27(35)11-12-28(24)31(30(25)37-20-26)39-14-15-40(33(42)23-7-3-1-2-4-8-23)29(21-39)32(41)38-19-22-6-5-13-36-18-22/h5-6,11-13,16-18,20,23,29,31H,1-4,7-10,14-15,19,21H2,(H,38,41)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177262 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES CCCCC(=O)N1CCN(CC1C(=O)NCCc1cnc[nH]1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C29H34BrClN6O2/c1-2-3-4-26(38)37-12-11-36(17-25(37)29(39)33-10-9-23-16-32-18-35-23)28-24-8-7-22(31)14-19(24)5-6-20-13-21(30)15-34-27(20)28/h7-8,13-16,18,25,28H,2-6,9-12,17H2,1H3,(H,32,35)(H,33,39)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177237 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES CC(C)(C)CC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C31H35BrClN5O2/c1-31(2,3)15-27(39)38-12-11-37(19-26(38)30(40)36-17-20-5-4-10-34-16-20)29-25-9-8-24(33)14-21(25)6-7-22-13-23(32)18-35-28(22)29/h4-5,8-10,13-14,16,18,26,29H,6-7,11-12,15,17,19H2,1-3H3,(H,36,40)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177265 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Cn1cncc1CCNC(=O)C1CN(CCN1C(=O)NC1CCCCC1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C32H39BrClN7O2/c1-39-20-35-18-26(39)11-12-36-31(42)28-19-40(13-14-41(28)32(43)38-25-5-3-2-4-6-25)30-27-10-9-24(34)16-21(27)7-8-22-15-23(33)17-37-29(22)30/h9-10,15-18,20,25,28,30H,2-8,11-14,19H2,1H3,(H,36,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against Ha-Ras processing in COS7 cells				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177252 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCCCc3cnc[nH]3)C(=O)NC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C32H39BrClN7O2/c33-23-15-22-9-8-21-16-24(34)10-11-27(21)30(29(22)37-17-23)40-13-14-41(32(43)39-25-5-2-1-3-6-25)28(19-40)31(42)36-12-4-7-26-18-35-20-38-26/h10-11,15-18,20,25,28,30H,1-9,12-14,19H2,(H,35,38)(H,36,42)(H,39,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177266 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES CN(C)C(=O)CCC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C31H34BrClN6O3/c1-37(2)27(40)9-10-28(41)39-13-12-38(19-26(39)31(42)36-17-20-4-3-11-34-16-20)30-25-8-7-24(33)15-21(25)5-6-22-14-23(32)18-35-29(22)30/h3-4,7-8,11,14-16,18,26,30H,5-6,9-10,12-13,17,19H2,1-2H3,(H,36,42)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177247 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCCCN3CCCC3=O)C(=O)NC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C33H42BrClN6O3/c34-24-18-23-10-9-22-19-25(35)11-12-27(22)31(30(23)37-20-24)40-16-17-41(33(44)38-26-6-2-1-3-7-26)28(21-40)32(43)36-13-5-15-39-14-4-8-29(39)42/h11-12,18-20,26,28,31H,1-10,13-17,21H2,(H,36,43)(H,38,44)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177256 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCc3cccnc3)C(=O)NC3CCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C31H34BrClN6O2/c32-23-14-22-8-7-21-15-24(33)9-10-26(21)29(28(22)35-18-23)38-12-13-39(31(41)37-25-5-1-2-6-25)27(19-38)30(40)36-17-20-4-3-11-34-16-20/h3-4,9-11,14-16,18,25,27,29H,1-2,5-8,12-13,17,19H2,(H,36,40)(H,37,41)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177264 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES CC(C)(C)NC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C30H34BrClN6O2/c1-30(2,3)36-29(40)38-12-11-37(18-25(38)28(39)35-16-19-5-4-10-33-15-19)27-24-9-8-23(32)14-20(24)6-7-21-13-22(31)17-34-26(21)27/h4-5,8-10,13-15,17,25,27H,6-7,11-12,16,18H2,1-3H3,(H,35,39)(H,36,40)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177240 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCc3cccnc3)C(=O)C3CCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C31H33BrClN5O2/c32-24-14-23-8-7-22-15-25(33)9-10-26(22)29(28(23)35-18-24)37-12-13-38(31(40)21-5-1-2-6-21)27(19-37)30(39)36-17-20-4-3-11-34-16-20/h3-4,9-11,14-16,18,21,27,29H,1-2,5-8,12-13,17,19H2,(H,36,39)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177258 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCCc3cnc[nH]3)C(=O)NC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C31H37BrClN7O2/c32-22-14-21-7-6-20-15-23(33)8-9-26(20)29(28(21)36-16-22)39-12-13-40(31(42)38-24-4-2-1-3-5-24)27(18-39)30(41)35-11-10-25-17-34-19-37-25/h8-9,14-17,19,24,27,29H,1-7,10-13,18H2,(H,34,37)(H,35,41)(H,38,42)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against Ha-Ras processing in COS7 cells				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177233 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES CCCCC(=O)N1CCN(CC1C(=O)Nc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C29H31BrClN5O2/c1-2-3-6-26(37)36-13-12-35(18-25(36)29(38)34-23-5-4-11-32-17-23)28-24-10-9-22(31)15-19(24)7-8-20-14-21(30)16-33-27(20)28/h4-5,9-11,14-17,25,28H,2-3,6-8,12-13,18H2,1H3,(H,34,38)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177269 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES CCCNC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C29H32BrClN6O2/c1-2-9-33-29(39)37-12-11-36(18-25(37)28(38)35-16-19-4-3-10-32-15-19)27-24-8-7-23(31)14-20(24)5-6-21-13-22(30)17-34-26(21)27/h3-4,7-8,10,13-15,17,25,27H,2,5-6,9,11-12,16,18H2,1H3,(H,33,39)(H,35,38)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177247 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCCCN3CCCC3=O)C(=O)NC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C33H42BrClN6O3/c34-24-18-23-10-9-22-19-25(35)11-12-27(22)31(30(23)37-20-24)40-16-17-41(33(44)38-26-6-2-1-3-7-26)28(21-40)32(43)36-13-5-15-39-14-4-8-29(39)42/h11-12,18-20,26,28,31H,1-10,13-17,21H2,(H,36,43)(H,38,44)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against Ha-Ras processing in COS7 cells				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177253 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCc3cccnc3)C(=O)CCC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C34H39BrClN5O2/c35-27-17-26-10-9-25-18-28(36)11-12-29(25)33(32(26)38-21-27)40-15-16-41(31(42)13-8-23-5-2-1-3-6-23)30(22-40)34(43)39-20-24-7-4-14-37-19-24/h4,7,11-12,14,17-19,21,23,30,33H,1-3,5-6,8-10,13,15-16,20,22H2,(H,39,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177259 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES COCCC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C29H31BrClN5O3/c1-39-12-8-26(37)36-11-10-35(18-25(36)29(38)34-16-19-3-2-9-32-15-19)28-24-7-6-23(31)14-20(24)4-5-21-13-22(30)17-33-27(21)28/h2-3,6-7,9,13-15,17,25,28H,4-5,8,10-12,16,18H2,1H3,(H,34,38)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177245 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES CCOCC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C29H31BrClN5O3/c1-2-39-18-26(37)36-11-10-35(17-25(36)29(38)34-15-19-4-3-9-32-14-19)28-24-8-7-23(31)13-20(24)5-6-21-12-22(30)16-33-27(21)28/h3-4,7-9,12-14,16,25,28H,2,5-6,10-11,15,17-18H2,1H3,(H,34,38)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177242 (4-(3-Bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES CC(C)(C)OC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C30H33BrClN5O3/c1-30(2,3)40-29(39)37-12-11-36(18-25(37)28(38)35-16-19-5-4-10-33-15-19)27-24-9-8-23(32)14-20(24)6-7-21-13-22(31)17-34-26(21)27/h4-5,8-10,13-15,17,25,27H,6-7,11-12,16,18H2,1-3H3,(H,35,38)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177230 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Cn1cnc(CCNC(=O)C2CN(CCN2C(=O)NC2CCCCC2)C2c3ccc(Cl)cc3CCc3cc(Br)cnc23)c1 Show InChI InChI=1S/C32H39BrClN7O2/c1-39-18-26(37-20-39)11-12-35-31(42)28-19-40(13-14-41(28)32(43)38-25-5-3-2-4-6-25)30-27-10-9-24(34)16-21(27)7-8-22-15-23(33)17-36-29(22)30/h9-10,15-18,20,25,28,30H,2-8,11-14,19H2,1H3,(H,35,42)(H,38,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177256 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCc3cccnc3)C(=O)NC3CCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C31H34BrClN6O2/c32-23-14-22-8-7-21-15-24(33)9-10-26(21)29(28(22)35-18-23)38-12-13-39(31(41)37-25-5-1-2-6-25)27(19-38)30(40)36-17-20-4-3-11-34-16-20/h3-4,9-11,14-16,18,25,27,29H,1-2,5-8,12-13,17,19H2,(H,36,40)(H,37,41)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against Ha-Ras processing in COS7 cells				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177253 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES Clc1ccc2C(N3CCN(C(C3)C(=O)NCc3cccnc3)C(=O)CCC3CCCCC3)c3ncc(Br)cc3CCc2c1 Show InChI InChI=1S/C34H39BrClN5O2/c35-27-17-26-10-9-25-18-28(36)11-12-29(25)33(32(26)38-21-27)40-15-16-41(31(42)13-8-23-5-2-1-3-6-23)30(22-40)34(43)39-20-24-7-4-14-37-19-24/h4,7,11-12,14,17-19,21,23,30,33H,1-3,5-6,8-10,13,15-16,20,22H2,(H,39,43)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against Ha-Ras processing in COS7 cells				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177261 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES CCCCC(=O)N1CCN(CC1C(=O)NCc1cnc[nH]1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C28H32BrClN6O2/c1-2-3-4-25(37)36-10-9-35(16-24(36)28(38)33-15-22-14-31-17-34-22)27-23-8-7-21(30)12-18(23)5-6-19-11-20(29)13-32-26(19)27/h7-8,11-14,17,24,27H,2-6,9-10,15-16H2,1H3,(H,31,34)(H,33,38)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against farnesyltransferase quantified by SPA assay				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair
Dimer of Protein farnesyltransferase subunit beta (Homo sapiens (Human))	BDBM50177235 (4-(3-bromo-8-chloro-6,11-dihydro-5H-benzo[5,6]cycl...) Show SMILES CCCCNC(=O)N1CCN(CC1C(=O)NCc1cccnc1)C1c2ccc(Cl)cc2CCc2cc(Br)cnc12 Show InChI InChI=1S/C30H34BrClN6O2/c1-2-3-11-34-30(40)38-13-12-37(19-26(38)29(39)36-17-20-5-4-10-33-16-20)28-25-9-8-24(32)15-21(25)6-7-22-14-23(31)18-35-27(22)28/h4-5,8-10,14-16,18,26,28H,2-3,6-7,11-13,17,19H2,1H3,(H,34,40)(H,36,39)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Princ Curated by ChEMBL					Assay Description Inhibitory activity against Ha-Ras processing in COS7 cells				Bioorg Med Chem Lett 16: 507-11 (2005) Article DOI: 10.1016/j.bmcl.2005.10.070 BindingDB Entry DOI: 10.7270/Q2M0450S
					More data for this Ligand-Target Pair

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