Compile Data Set for Download or QSAR

Found 44 hits Enz. Inhib. hit(s) with all data for entry = 50017148   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178254 (3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(3-(1-methyl-1,2...) Show SMILES CN1CCNc2nc(CCCc3nc(CC(CC(O)=O)c4ccc5OCOc5c4)cs3)ccc12 Show InChI InChI=1S/C25H28N4O4S/c1-29-10-9-26-25-20(29)7-6-18(28-25)3-2-4-23-27-19(14-34-23)11-17(13-24(30)31)16-5-8-21-22(12-16)33-15-32-21/h5-8,12,14,17H,2-4,9-11,13,15H2,1H3,(H,26,28)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.610	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178253 (3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(3-(5,6,7,8-tetr...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C25H27N3O4S/c29-24(30)13-18(17-7-9-21-22(12-17)32-15-31-21)11-20-14-33-23(27-20)5-1-4-19-8-6-16-3-2-10-26-25(16)28-19/h6-9,12,14,18H,1-5,10-11,13,15H2,(H,26,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.18	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178243 (3-(2-(methoxymethyl)thiazol-5-yl)-4-(2-(3-(5,6,7,8...) Show SMILES COCc1ncc(s1)C(CC(O)=O)Cc1csc(CCCc2ccc3CCCNc3n2)n1 Show InChI InChI=1S/C23H28N4O3S2/c1-30-13-21-25-12-19(32-21)16(11-22(28)29)10-18-14-31-20(26-18)6-2-5-17-8-7-15-4-3-9-24-23(15)27-17/h7-8,12,14,16H,2-6,9-11,13H2,1H3,(H,24,27)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178245 (3-(2-cyclopropylthiazol-5-yl)-4-(2-(3-(5,6,7,8-tet...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1cnc(s1)C1CC1 Show InChI InChI=1S/C24H28N4O2S2/c29-22(30)12-17(20-13-26-24(32-20)16-6-7-16)11-19-14-31-21(27-19)5-1-4-18-9-8-15-3-2-10-25-23(15)28-18/h8-9,13-14,16-17H,1-7,10-12H2,(H,25,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.22	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178242 (3-(6-methoxypyridin-3-yl)-4-(2-(3-(5,6,7,8-tetrahy...) Show SMILES COc1ccc(cn1)C(CC(O)=O)Cc1csc(CCCc2ccc3CCCNc3n2)n1 Show InChI InChI=1S/C24H28N4O3S/c1-31-21-10-8-17(14-26-21)18(13-23(29)30)12-20-15-32-22(27-20)6-2-5-19-9-7-16-4-3-11-25-24(16)28-19/h7-10,14-15,18H,2-6,11-13H2,1H3,(H,25,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.23	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178255 (3-(6-methoxypyridin-3-yl)-4-(2-(3-(1-methyl-1,2,3,...) Show SMILES COc1ccc(cn1)C(CC(O)=O)Cc1csc(CCCc2ccc3N(C)CCNc3n2)n1 Show InChI InChI=1S/C24H29N5O3S/c1-29-11-10-25-24-20(29)8-7-18(28-24)4-3-5-22-27-19(15-33-22)12-17(13-23(30)31)16-6-9-21(32-2)26-14-16/h6-9,14-15,17H,3-5,10-13H2,1-2H3,(H,25,28)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.24	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178247 ((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(4-(4-(pyrro...) Show SMILES OC(=O)C[C@H](Cc1csc(CCCCNc2cc(ccn2)N2CCCC2)n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H32N4O4S/c32-27(33)15-20(19-6-7-23-24(14-19)35-18-34-23)13-21-17-36-26(30-21)5-1-2-9-28-25-16-22(8-10-29-25)31-11-3-4-12-31/h6-8,10,14,16-17,20H,1-5,9,11-13,15,18H2,(H,28,29)(H,32,33)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.26	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178248 (3-(3,5-dimethoxyphenyl)-4-(2-(3-(5,6,7,8-tetrahydr...) Show SMILES COc1cc(OC)cc(c1)C(CC(O)=O)Cc1csc(CCCc2ccc3CCCNc3n2)n1 Show InChI InChI=1S/C26H31N3O4S/c1-32-22-12-19(13-23(15-22)33-2)18(14-25(30)31)11-21-16-34-24(28-21)7-3-6-20-9-8-17-5-4-10-27-26(17)29-20/h8-9,12-13,15-16,18H,3-7,10-11,14H2,1-2H3,(H,27,29)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.54	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178250 ((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(4-(4-morpho...) Show SMILES OC(=O)C[C@H](Cc1csc(CCCCNc2cc(ccn2)N2CCOCC2)n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H32N4O5S/c32-27(33)15-20(19-4-5-23-24(14-19)36-18-35-23)13-21-17-37-26(30-21)3-1-2-7-28-25-16-22(6-8-29-25)31-9-11-34-12-10-31/h4-6,8,14,16-17,20H,1-3,7,9-13,15,18H2,(H,28,29)(H,32,33)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.56	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178257 ((S)-3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(4-(4-thiomo...) Show SMILES OC(=O)C[C@H](Cc1csc(CCCCNc2cc(ccn2)N2CCSCC2)n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H32N4O4S2/c32-27(33)15-20(19-4-5-23-24(14-19)35-18-34-23)13-21-17-37-26(30-21)3-1-2-7-28-25-16-22(6-8-29-25)31-9-11-36-12-10-31/h4-6,8,14,16-17,20H,1-3,7,9-13,15,18H2,(H,28,29)(H,32,33)/t20-/m0/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178240 (3-(2-phenylthiazol-5-yl)-4-(2-(3-(5,6,7,8-tetrahyd...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1cnc(s1)-c1ccccc1 Show InChI InChI=1S/C27H28N4O2S2/c32-25(33)15-20(23-16-29-27(35-23)19-6-2-1-3-7-19)14-22-17-34-24(30-22)10-4-9-21-12-11-18-8-5-13-28-26(18)31-21/h1-3,6-7,11-12,16-17,20H,4-5,8-10,13-15H2,(H,28,31)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.77	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178238 (3-(2-(4-chlorophenyl)thiazol-5-yl)-4-(2-(3-(5,6,7,...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1cnc(s1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C27H27ClN4O2S2/c28-20-9-6-18(7-10-20)27-30-15-23(36-27)19(14-25(33)34)13-22-16-35-24(31-22)5-1-4-21-11-8-17-3-2-12-29-26(17)32-21/h6-11,15-16,19H,1-5,12-14H2,(H,29,32)(H,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.09	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178241 (CHEMBL202054 | b3-(3-fluoro-4-methoxyphenyl)-4-(2-...) Show SMILES COc1ccc(cc1F)C(CC(O)=O)Cc1csc(CCCc2ccc3CCCNc3n2)n1 Show InChI InChI=1S/C25H28FN3O3S/c1-32-22-10-8-17(13-21(22)26)18(14-24(30)31)12-20-15-33-23(28-20)6-2-5-19-9-7-16-4-3-11-27-25(16)29-19/h7-10,13,15,18H,2-6,11-12,14H2,1H3,(H,27,29)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.17	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178239 (3-(3-fluorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro-1,8...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1cccc(F)c1 Show InChI InChI=1S/C24H26FN3O2S/c25-19-6-1-4-17(12-19)18(14-23(29)30)13-21-15-31-22(27-21)8-2-7-20-10-9-16-5-3-11-26-24(16)28-20/h1,4,6,9-10,12,15,18H,2-3,5,7-8,11,13-14H2,(H,26,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178252 (3-(2-methylbenzo[d]thiazol-5-yl)-4-(2-(3-(5,6,7,8-...) Show SMILES Cc1nc2cc(ccc2s1)C(CC(O)=O)Cc1csc(CCCc2ccc3CCCNc3n2)n1 Show InChI InChI=1S/C26H28N4O2S2/c1-16-28-22-13-18(8-10-23(22)34-16)19(14-25(31)32)12-21-15-33-24(29-21)6-2-5-20-9-7-17-4-3-11-27-26(17)30-20/h7-10,13,15,19H,2-6,11-12,14H2,1H3,(H,27,30)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.82	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178256 (3-(6-methoxypyridin-3-yl)-4-(2-(4-(4-(pyrrolidin-1...) Show SMILES COc1ccc(cn1)C(CC(O)=O)Cc1csc(CCCCNc2cc(ccn2)N2CCCC2)n1 Show InChI InChI=1S/C26H33N5O3S/c1-34-24-8-7-19(17-29-24)20(15-26(32)33)14-21-18-35-25(30-21)6-2-3-10-27-23-16-22(9-11-28-23)31-12-4-5-13-31/h7-9,11,16-18,20H,2-6,10,12-15H2,1H3,(H,27,28)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178251 (3-(3,4-difluorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1ccc(F)c(F)c1 Show InChI InChI=1S/C24H25F2N3O2S/c25-20-9-7-16(12-21(20)26)17(13-23(30)31)11-19-14-32-22(28-19)5-1-4-18-8-6-15-3-2-10-27-24(15)29-18/h6-9,12,14,17H,1-5,10-11,13H2,(H,27,29)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.49	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178258 (3-(6-methoxypyridin-3-yl)-4-(2-(4-(4-morpholinopyr...) Show SMILES COc1ccc(cn1)C(CC(O)=O)Cc1csc(CCCCNc2cc(ccn2)N2CCOCC2)n1 Show InChI InChI=1S/C26H33N5O4S/c1-34-24-6-5-19(17-29-24)20(15-26(32)33)14-21-18-36-25(30-21)4-2-3-8-27-23-16-22(7-9-28-23)31-10-12-35-13-11-31/h5-7,9,16-18,20H,2-4,8,10-15H2,1H3,(H,27,28)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.54	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178249 (3-(6-methoxypyridin-3-yl)-4-(2-(4-(4-thiomorpholin...) Show SMILES COc1ccc(cn1)C(CC(O)=O)Cc1csc(CCCCNc2cc(ccn2)N2CCSCC2)n1 Show InChI InChI=1S/C26H33N5O3S2/c1-34-24-6-5-19(17-29-24)20(15-26(32)33)14-21-18-36-25(30-21)4-2-3-8-27-23-16-22(7-9-28-23)31-10-12-35-13-11-31/h5-7,9,16-18,20H,2-4,8,10-15H2,1H3,(H,27,28)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.73	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178246 (3-(4-chlorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro-1,8...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H26ClN3O2S/c25-19-9-6-16(7-10-19)18(14-23(29)30)13-21-15-31-22(27-21)5-1-4-20-11-8-17-3-2-12-26-24(17)28-20/h6-11,15,18H,1-5,12-14H2,(H,26,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.81	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-3 (Homo sapiens (Human))	BDBM50178244 (4-(2-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)...) Show SMILES Cc1ccc(cc1)C(CC(O)=O)Cc1csc(CCCc2ccc3CCCNc3n2)n1 Show InChI InChI=1S/C25H29N3O2S/c1-17-7-9-18(10-8-17)20(15-24(29)30)14-22-16-31-23(27-22)6-2-5-21-12-11-19-4-3-13-26-25(19)28-21/h7-12,16,20H,2-6,13-15H2,1H3,(H,26,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	11.1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50178252 (3-(2-methylbenzo[d]thiazol-5-yl)-4-(2-(3-(5,6,7,8-...) Show SMILES Cc1nc2cc(ccc2s1)C(CC(O)=O)Cc1csc(CCCc2ccc3CCCNc3n2)n1 Show InChI InChI=1S/C26H28N4O2S2/c1-16-28-22-13-18(8-10-23(22)34-16)19(14-25(31)32)12-21-15-33-24(29-21)6-2-5-20-9-7-17-4-3-11-27-26(17)30-20/h7-10,13,15,19H,2-6,11-12,14H2,1H3,(H,27,30)(H,31,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	95.1	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50178240 (3-(2-phenylthiazol-5-yl)-4-(2-(3-(5,6,7,8-tetrahyd...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1cnc(s1)-c1ccccc1 Show InChI InChI=1S/C27H28N4O2S2/c32-25(33)15-20(23-16-29-27(35-23)19-6-2-1-3-7-19)14-22-17-34-24(30-22)10-4-9-21-12-11-18-8-5-13-28-26(18)31-21/h1-3,6-7,11-12,16-17,20H,4-5,8-10,13-15H2,(H,28,31)(H,32,33)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	252	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50178253 (3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(3-(5,6,7,8-tetr...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C25H27N3O4S/c29-24(30)13-18(17-7-9-21-22(12-17)32-15-31-21)11-20-14-33-23(27-20)5-1-4-19-8-6-16-3-2-10-26-25(16)28-19/h6-9,12,14,18H,1-5,10-11,13,15H2,(H,26,28)(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	263	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-6 (Homo sapiens (Human))	BDBM50178245 (3-(2-cyclopropylthiazol-5-yl)-4-(2-(3-(5,6,7,8-tet...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1cnc(s1)C1CC1 Show InChI InChI=1S/C24H28N4O2S2/c29-22(30)12-17(20-13-26-24(32-20)16-6-7-16)11-19-14-31-21(27-19)5-1-4-18-9-8-15-3-2-10-25-23(15)28-18/h8-9,13-14,16-17H,1-7,10-12H2,(H,25,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	313	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50178248 (3-(3,5-dimethoxyphenyl)-4-(2-(3-(5,6,7,8-tetrahydr...) Show SMILES COc1cc(OC)cc(c1)C(CC(O)=O)Cc1csc(CCCc2ccc3CCCNc3n2)n1 Show InChI InChI=1S/C26H31N3O4S/c1-32-22-12-19(13-23(15-22)33-2)18(14-25(30)31)11-21-16-34-24(28-21)7-3-6-20-9-8-17-5-4-10-27-26(17)29-20/h8-9,12-13,15-16,18H,3-7,10-11,14H2,1-2H3,(H,27,29)(H,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	350	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50178241 (CHEMBL202054 | b3-(3-fluoro-4-methoxyphenyl)-4-(2-...) Show SMILES COc1ccc(cc1F)C(CC(O)=O)Cc1csc(CCCc2ccc3CCCNc3n2)n1 Show InChI InChI=1S/C25H28FN3O3S/c1-32-22-10-8-17(13-21(22)26)18(14-24(30)31)12-20-15-33-23(28-20)6-2-5-19-9-7-16-4-3-11-27-25(16)29-19/h7-10,13,15,18H,2-6,11-12,14H2,1H3,(H,27,29)(H,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	405	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50178251 (3-(3,4-difluorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1ccc(F)c(F)c1 Show InChI InChI=1S/C24H25F2N3O2S/c25-20-9-7-16(12-21(20)26)17(13-23(30)31)11-19-14-32-22(28-19)5-1-4-18-8-6-15-3-2-10-27-24(15)29-18/h6-9,12,14,17H,1-5,10-11,13H2,(H,27,29)(H,30,31)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	484	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50178238 (3-(2-(4-chlorophenyl)thiazol-5-yl)-4-(2-(3-(5,6,7,...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1cnc(s1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C27H27ClN4O2S2/c28-20-9-6-18(7-10-20)27-30-15-23(36-27)19(14-25(33)34)13-22-16-35-24(31-22)5-1-4-21-11-8-17-3-2-12-29-26(17)32-21/h6-11,15-16,19H,1-5,12-14H2,(H,29,32)(H,33,34)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	559	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50178239 (3-(3-fluorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro-1,8...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1cccc(F)c1 Show InChI InChI=1S/C24H26FN3O2S/c25-19-6-1-4-17(12-19)18(14-23(29)30)13-21-15-31-22(27-21)8-2-7-20-10-9-16-5-3-11-26-24(16)28-20/h1,4,6,9-10,12,15,18H,2-3,5,7-8,11,13-14H2,(H,26,28)(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	559	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50178246 (3-(4-chlorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro-1,8...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H26ClN3O2S/c25-19-9-6-16(7-10-19)18(14-23(29)30)13-21-15-31-22(27-21)5-1-4-20-11-8-17-3-2-12-26-24(17)28-20/h6-11,15,18H,1-5,12-14H2,(H,26,28)(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	636	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-6 (Homo sapiens (Human))	BDBM50178243 (3-(2-(methoxymethyl)thiazol-5-yl)-4-(2-(3-(5,6,7,8...) Show SMILES COCc1ncc(s1)C(CC(O)=O)Cc1csc(CCCc2ccc3CCCNc3n2)n1 Show InChI InChI=1S/C23H28N4O3S2/c1-30-13-21-25-12-19(32-21)16(11-22(28)29)10-18-14-31-20(26-18)6-2-5-17-8-7-15-4-3-9-24-23(15)27-17/h7-8,12,14,16H,2-6,9-11,13H2,1H3,(H,24,27)(H,28,29)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	841	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-6 (Homo sapiens (Human))	BDBM50178239 (3-(3-fluorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro-1,8...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1cccc(F)c1 Show InChI InChI=1S/C24H26FN3O2S/c25-19-6-1-4-17(12-19)18(14-23(29)30)13-21-15-31-22(27-21)8-2-7-20-10-9-16-5-3-11-26-24(16)28-20/h1,4,6,9-10,12,15,18H,2-3,5,7-8,11,13-14H2,(H,26,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.31E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-6 (Homo sapiens (Human))	BDBM50178242 (3-(6-methoxypyridin-3-yl)-4-(2-(3-(5,6,7,8-tetrahy...) Show SMILES COc1ccc(cn1)C(CC(O)=O)Cc1csc(CCCc2ccc3CCCNc3n2)n1 Show InChI InChI=1S/C24H28N4O3S/c1-31-21-10-8-17(14-26-21)18(13-23(29)30)12-20-15-32-22(27-20)6-2-5-19-9-7-16-4-3-11-25-24(16)28-19/h7-10,14-15,18H,2-6,11-13H2,1H3,(H,25,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-6 (Homo sapiens (Human))	BDBM50178248 (3-(3,5-dimethoxyphenyl)-4-(2-(3-(5,6,7,8-tetrahydr...) Show SMILES COc1cc(OC)cc(c1)C(CC(O)=O)Cc1csc(CCCc2ccc3CCCNc3n2)n1 Show InChI InChI=1S/C26H31N3O4S/c1-32-22-12-19(13-23(15-22)33-2)18(14-25(30)31)11-21-16-34-24(28-21)7-3-6-20-9-8-17-5-4-10-27-26(17)29-20/h8-9,12-13,15-16,18H,3-7,10-11,14H2,1-2H3,(H,27,29)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.74E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-IIb/beta-3 (Homo sapiens (Human))	BDBM50178244 (4-(2-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)...) Show SMILES Cc1ccc(cc1)C(CC(O)=O)Cc1csc(CCCc2ccc3CCCNc3n2)n1 Show InChI InChI=1S/C25H29N3O2S/c1-17-7-9-18(10-8-17)20(15-24(29)30)14-22-16-31-23(27-22)6-2-5-21-12-11-19-4-3-13-26-25(19)28-21/h7-12,16,20H,2-6,13-15H2,1H3,(H,26,28)(H,29,30)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaIIb Beta3 receptor by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-6 (Homo sapiens (Human))	BDBM50178251 (3-(3,4-difluorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1ccc(F)c(F)c1 Show InChI InChI=1S/C24H25F2N3O2S/c25-20-9-7-16(12-21(20)26)17(13-23(30)31)11-19-14-32-22(28-19)5-1-4-18-8-6-15-3-2-10-27-24(15)29-18/h6-9,12,14,17H,1-5,10-11,13H2,(H,27,29)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.12E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-6 (Homo sapiens (Human))	BDBM50178253 (3-(benzo[d][1,3]dioxol-5-yl)-4-(2-(3-(5,6,7,8-tetr...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1ccc2OCOc2c1 Show InChI InChI=1S/C25H27N3O4S/c29-24(30)13-18(17-7-9-21-22(12-17)32-15-31-21)11-20-14-33-23(27-20)5-1-4-19-8-6-16-3-2-10-26-25(16)28-19/h6-9,12,14,18H,1-5,10-11,13,15H2,(H,26,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-6 (Homo sapiens (Human))	BDBM50178246 (3-(4-chlorophenyl)-4-(2-(3-(5,6,7,8-tetrahydro-1,8...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H26ClN3O2S/c25-19-9-6-16(7-10-19)18(14-23(29)30)13-21-15-31-22(27-21)5-1-4-20-11-8-17-3-2-12-26-24(17)28-20/h6-11,15,18H,1-5,12-14H2,(H,26,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-6 (Homo sapiens (Human))	BDBM50178240 (3-(2-phenylthiazol-5-yl)-4-(2-(3-(5,6,7,8-tetrahyd...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1cnc(s1)-c1ccccc1 Show InChI InChI=1S/C27H28N4O2S2/c32-25(33)15-20(23-16-29-27(35-23)19-6-2-1-3-7-19)14-22-17-34-24(30-22)10-4-9-21-12-11-18-8-5-13-28-26(18)31-21/h1-3,6-7,11-12,16-17,20H,4-5,8-10,13-15H2,(H,28,31)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-6 (Homo sapiens (Human))	BDBM50178241 (CHEMBL202054 | b3-(3-fluoro-4-methoxyphenyl)-4-(2-...) Show SMILES COc1ccc(cc1F)C(CC(O)=O)Cc1csc(CCCc2ccc3CCCNc3n2)n1 Show InChI InChI=1S/C25H28FN3O3S/c1-32-22-10-8-17(13-21(22)26)18(14-24(30)31)12-20-15-33-23(28-20)6-2-5-19-9-7-16-4-3-11-27-25(16)29-19/h7-10,13,15,18H,2-6,11-12,14H2,1H3,(H,27,29)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-6 (Homo sapiens (Human))	BDBM50178238 (3-(2-(4-chlorophenyl)thiazol-5-yl)-4-(2-(3-(5,6,7,...) Show SMILES OC(=O)CC(Cc1csc(CCCc2ccc3CCCNc3n2)n1)c1cnc(s1)-c1ccc(Cl)cc1 Show InChI InChI=1S/C27H27ClN4O2S2/c28-20-9-6-18(7-10-20)27-30-15-23(36-27)19(14-25(33)34)13-22-16-35-24(31-22)5-1-4-21-11-8-17-3-2-12-29-26(17)32-21/h6-11,15-16,19H,1-5,12-14H2,(H,29,32)(H,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-6 (Homo sapiens (Human))	BDBM50178244 (4-(2-(3-(5,6,7,8-tetrahydro-1,8-naphthyridin-2-yl)...) Show SMILES Cc1ccc(cc1)C(CC(O)=O)Cc1csc(CCCc2ccc3CCCNc3n2)n1 Show InChI InChI=1S/C25H29N3O2S/c1-17-7-9-18(10-8-17)20(15-24(29)30)14-22-16-31-23(27-22)6-2-5-21-12-11-19-4-3-13-26-25(19)28-21/h7-12,16,20H,2-6,13-15H2,1H3,(H,26,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair
Integrin alpha-V/beta-6 (Homo sapiens (Human))	BDBM50178252 (3-(2-methylbenzo[d]thiazol-5-yl)-4-(2-(3-(5,6,7,8-...) Show SMILES Cc1nc2cc(ccc2s1)C(CC(O)=O)Cc1csc(CCCc2ccc3CCCNc3n2)n1 Show InChI InChI=1S/C26H28N4O2S2/c1-16-28-22-13-18(8-10-23(22)34-16)19(14-25(31)32)12-21-15-33-24(29-21)6-2-5-20-9-7-17-4-3-11-27-26(17)30-20/h7-10,13,15,19H,2-6,11-12,14H2,1H3,(H,27,30)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of Integrin alphaV Beta6 receptor in HT29 cells by solid-phase receptor binding assay				Bioorg Med Chem Lett 16: 845-9 (2006) Article DOI: 10.1016/j.bmcl.2005.11.017 BindingDB Entry DOI: 10.7270/Q2PN956J
					More data for this Ligand-Target Pair