Compile Data Set for Download or QSAR

Found 50 hits Enz. Inhib. hit(s) with all data for entry = 50017268   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179924 (4-(2-fluoro-5-(7-(2-hydroxypropan-2-yl)imidazo[1,2...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccncc1C#N Show InChI InChI=1S/C21H16FN5O/c1-21(2,28)19-6-8-27-18(12-25-20(27)26-19)13-3-4-17(22)16(9-13)15-5-7-24-11-14(15)10-23/h3-9,11-12,28H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179924 (4-(2-fluoro-5-(7-(2-hydroxypropan-2-yl)imidazo[1,2...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccncc1C#N Show InChI InChI=1S/C21H16FN5O/c1-21(2,28)19-6-8-27-18(12-25-20(27)26-19)13-3-4-17(22)16(9-13)15-5-7-24-11-14(15)10-23/h3-9,11-12,28H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179919 (2-(3-(4-fluoro-3-(pyridin-4-yl)phenyl)imidazo[1,2-...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccncc1 Show InChI InChI=1S/C20H17FN4O/c1-20(2,26)18-7-10-25-17(12-23-19(25)24-18)14-3-4-16(21)15(11-14)13-5-8-22-9-6-13/h3-12,26H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179923 (4-(2-fluoro-5-(3-(2-hydroxypropan-2-yl)imidazo[1,2...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccncc1C#N Show InChI InChI=1S/C20H15FN6O/c1-20(2,28)18-11-25-27-17(10-24-19(27)26-18)12-3-4-16(21)15(7-12)14-5-6-23-9-13(14)8-22/h3-7,9-11,28H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179925 (2-(3-(4-fluoro-3-(3-fluoropyridin-2-yl)phenyl)imid...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncccc1F Show InChI InChI=1S/C20H16F2N4O/c1-20(2,27)17-7-9-26-16(11-24-19(26)25-17)12-5-6-14(21)13(10-12)18-15(22)4-3-8-23-18/h3-11,27H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179918 (2-(3-(4-fluoro-3-(5-fluoropyridin-2-yl)phenyl)imid...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccc(F)cn1 Show InChI InChI=1S/C20H16F2N4O/c1-20(2,27)18-7-8-26-17(11-24-19(26)25-18)12-3-5-15(22)14(9-12)16-6-4-13(21)10-23-16/h3-11,27H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179928 (2-(7-(4-fluoro-3-(pyridin-3-yl)phenyl)imidazo[1,2-...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1cccnc1 Show InChI InChI=1S/C19H16FN5O/c1-19(2,26)17-11-23-25-16(10-22-18(25)24-17)12-5-6-15(20)14(8-12)13-4-3-7-21-9-13/h3-11,26H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179927 (2-(7-(4-fluoro-3-(pyridin-4-yl)phenyl)imidazo[1,2-...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccncc1 Show InChI InChI=1S/C19H16FN5O/c1-19(2,26)17-11-23-25-16(10-22-18(25)24-17)13-3-4-15(20)14(9-13)12-5-7-21-8-6-12/h3-11,26H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179927 (2-(7-(4-fluoro-3-(pyridin-4-yl)phenyl)imidazo[1,2-...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccncc1 Show InChI InChI=1S/C19H16FN5O/c1-19(2,26)17-11-23-25-16(10-22-18(25)24-17)13-3-4-15(20)14(9-13)12-5-7-21-8-6-12/h3-11,26H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179849 (2-(3-(4-fluoro-3-(pyridin-3-yl)phenyl)imidazo[1,2-...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1cccnc1 Show InChI InChI=1S/C20H17FN4O/c1-20(2,26)18-7-9-25-17(12-23-19(25)24-18)13-5-6-16(21)15(10-13)14-4-3-8-22-11-14/h3-12,26H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179927 (2-(7-(4-fluoro-3-(pyridin-4-yl)phenyl)imidazo[1,2-...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccncc1 Show InChI InChI=1S/C19H16FN5O/c1-19(2,26)17-11-23-25-16(10-22-18(25)24-17)13-3-4-15(20)14(9-13)12-5-7-21-8-6-12/h3-11,26H,1-2H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179924 (4-(2-fluoro-5-(7-(2-hydroxypropan-2-yl)imidazo[1,2...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccncc1C#N Show InChI InChI=1S/C21H16FN5O/c1-21(2,28)19-6-8-27-18(12-25-20(27)26-19)13-3-4-17(22)16(9-13)15-5-7-24-11-14(15)10-23/h3-9,11-12,28H,1-2H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179922 (4-(2-fluoro-5-(3-(2-hydroxypropan-2-yl)imidazo[1,2...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncncc1C#N Show InChI InChI=1S/C19H14FN7O/c1-19(2,28)16-9-25-27-15(8-23-18(27)26-16)11-3-4-14(20)13(5-11)17-12(6-21)7-22-10-24-17/h3-5,7-10,28H,1-2H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179920 (2-(7-(3-(3,5-difluoropyridin-2-yl)-4-fluorophenyl)...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncc(F)cc1F Show InChI InChI=1S/C19H14F3N5O/c1-19(2,28)16-9-25-27-15(8-24-18(27)26-16)10-3-4-13(21)12(5-10)17-14(22)6-11(20)7-23-17/h3-9,28H,1-2H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179926 (2-(2-fluoro-5-(7-(2-hydroxypropan-2-yl)imidazo[1,2...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncccc1C#N Show InChI InChI=1S/C21H16FN5O/c1-21(2,28)18-7-9-27-17(12-25-20(27)26-18)13-5-6-16(22)15(10-13)19-14(11-23)4-3-8-24-19/h3-10,12,28H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179919 (2-(3-(4-fluoro-3-(pyridin-4-yl)phenyl)imidazo[1,2-...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccncc1 Show InChI InChI=1S/C20H17FN4O/c1-20(2,26)18-7-10-25-17(12-23-19(25)24-18)14-3-4-16(21)15(11-14)13-5-8-22-9-6-13/h3-12,26H,1-2H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179923 (4-(2-fluoro-5-(3-(2-hydroxypropan-2-yl)imidazo[1,2...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccncc1C#N Show InChI InChI=1S/C20H15FN6O/c1-20(2,28)18-11-25-27-17(10-24-19(27)26-18)12-3-4-16(21)15(7-12)14-5-6-23-9-13(14)8-22/h3-7,9-11,28H,1-2H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179925 (2-(3-(4-fluoro-3-(3-fluoropyridin-2-yl)phenyl)imid...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncccc1F Show InChI InChI=1S/C20H16F2N4O/c1-20(2,27)17-7-9-26-16(11-24-19(26)25-17)12-5-6-14(21)13(10-12)18-15(22)4-3-8-23-18/h3-11,27H,1-2H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179928 (2-(7-(4-fluoro-3-(pyridin-3-yl)phenyl)imidazo[1,2-...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1cccnc1 Show InChI InChI=1S/C19H16FN5O/c1-19(2,26)17-11-23-25-16(10-22-18(25)24-17)12-5-6-15(20)14(8-12)13-4-3-7-21-9-13/h3-11,26H,1-2H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.810	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179849 (2-(3-(4-fluoro-3-(pyridin-3-yl)phenyl)imidazo[1,2-...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1cccnc1 Show InChI InChI=1S/C20H17FN4O/c1-20(2,26)18-7-9-25-17(12-23-19(25)24-18)13-5-6-16(21)15(10-13)14-4-3-8-22-11-14/h3-12,26H,1-2H3	GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.850	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-2/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179927 (2-(7-(4-fluoro-3-(pyridin-4-yl)phenyl)imidazo[1,2-...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccncc1 Show InChI InChI=1S/C19H16FN5O/c1-19(2,26)17-11-23-25-16(10-22-18(25)24-17)13-3-4-15(20)14(9-13)12-5-7-21-8-6-12/h3-11,26H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.920	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha2 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179923 (4-(2-fluoro-5-(3-(2-hydroxypropan-2-yl)imidazo[1,2...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccncc1C#N Show InChI InChI=1S/C20H15FN6O/c1-20(2,28)18-11-25-27-17(10-24-19(27)26-18)12-3-4-16(21)15(7-12)14-5-6-23-9-13(14)8-22/h3-7,9-11,28H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.06	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179915 (2-(3-(3-(3,5-difluoropyridin-2-yl)-4-fluorophenyl)...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncc(F)cc1F Show InChI InChI=1S/C20H15F3N4O/c1-20(2,28)17-5-6-27-16(10-25-19(27)26-17)11-3-4-14(22)13(7-11)18-15(23)8-12(21)9-24-18/h3-10,28H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179917 (2-(7-(4-fluoro-3-(5-fluoropyridin-2-yl)phenyl)imid...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccc(F)cn1 Show InChI InChI=1S/C19H15F2N5O/c1-19(2,27)17-10-24-26-16(9-23-18(26)25-17)11-3-5-14(21)13(7-11)15-6-4-12(20)8-22-15/h3-10,27H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179925 (2-(3-(4-fluoro-3-(3-fluoropyridin-2-yl)phenyl)imid...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncccc1F Show InChI InChI=1S/C20H16F2N4O/c1-20(2,27)17-7-9-26-16(11-24-19(26)25-17)12-5-6-14(21)13(10-12)18-15(22)4-3-8-23-18/h3-11,27H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179916 (2-(2-fluoro-5-(3-(2-hydroxypropan-2-yl)imidazo[1,2...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncccc1C#N Show InChI InChI=1S/C20H15FN6O/c1-20(2,28)17-11-25-27-16(10-24-19(27)26-17)12-5-6-15(21)14(8-12)18-13(9-22)4-3-7-23-18/h3-8,10-11,28H,1-2H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179926 (2-(2-fluoro-5-(7-(2-hydroxypropan-2-yl)imidazo[1,2...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncccc1C#N Show InChI InChI=1S/C21H16FN5O/c1-21(2,28)18-7-9-27-17(12-25-20(27)26-18)13-5-6-16(22)15(10-13)19-14(11-23)4-3-8-24-19/h3-10,12,28H,1-2H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179917 (2-(7-(4-fluoro-3-(5-fluoropyridin-2-yl)phenyl)imid...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccc(F)cn1 Show InChI InChI=1S/C19H15F2N5O/c1-19(2,27)17-10-24-26-16(9-23-18(26)25-17)11-3-5-14(21)13(7-11)15-6-4-12(20)8-22-15/h3-10,27H,1-2H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-2/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179923 (4-(2-fluoro-5-(3-(2-hydroxypropan-2-yl)imidazo[1,2...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccncc1C#N Show InChI InChI=1S/C20H15FN6O/c1-20(2,28)18-11-25-27-17(10-24-19(27)26-18)12-3-4-16(21)15(7-12)14-5-6-23-9-13(14)8-22/h3-7,9-11,28H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha2 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179921 (2-(7-(4-fluoro-3-(3-fluoropyridin-2-yl)phenyl)imid...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncccc1F Show InChI InChI=1S/C19H15F2N5O/c1-19(2,27)16-10-24-26-15(9-23-18(26)25-16)11-5-6-13(20)12(8-11)17-14(21)4-3-7-22-17/h3-10,27H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179918 (2-(3-(4-fluoro-3-(5-fluoropyridin-2-yl)phenyl)imid...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccc(F)cn1 Show InChI InChI=1S/C20H16F2N4O/c1-20(2,27)18-7-8-26-17(11-24-19(26)25-18)12-3-5-15(22)14(9-12)16-6-4-13(21)10-23-16/h3-11,27H,1-2H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179928 (2-(7-(4-fluoro-3-(pyridin-3-yl)phenyl)imidazo[1,2-...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1cccnc1 Show InChI InChI=1S/C19H16FN5O/c1-19(2,26)17-11-23-25-16(10-22-18(25)24-17)12-5-6-15(20)14(8-12)13-4-3-7-21-9-13/h3-11,26H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.63	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179915 (2-(3-(3-(3,5-difluoropyridin-2-yl)-4-fluorophenyl)...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncc(F)cc1F Show InChI InChI=1S/C20H15F3N4O/c1-20(2,28)17-5-6-27-16(10-25-19(27)26-17)11-3-4-14(22)13(7-11)18-15(23)8-12(21)9-24-18/h3-10,28H,1-2H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.79	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179918 (2-(3-(4-fluoro-3-(5-fluoropyridin-2-yl)phenyl)imid...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccc(F)cn1 Show InChI InChI=1S/C20H16F2N4O/c1-20(2,27)18-7-8-26-17(11-24-19(26)25-18)12-3-5-15(22)14(9-12)16-6-4-13(21)10-23-16/h3-11,27H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.94	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179921 (2-(7-(4-fluoro-3-(3-fluoropyridin-2-yl)phenyl)imid...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncccc1F Show InChI InChI=1S/C19H15F2N5O/c1-19(2,27)16-10-24-26-15(9-23-18(26)25-16)11-5-6-13(20)12(8-11)17-14(21)4-3-7-22-17/h3-10,27H,1-2H3	GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.01	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha1 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179919 (2-(3-(4-fluoro-3-(pyridin-4-yl)phenyl)imidazo[1,2-...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccncc1 Show InChI InChI=1S/C20H17FN4O/c1-20(2,26)18-7-10-25-17(12-23-19(25)24-18)14-3-4-16(21)15(11-14)13-5-8-22-9-6-13/h3-12,26H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-2/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179917 (2-(7-(4-fluoro-3-(5-fluoropyridin-2-yl)phenyl)imid...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccc(F)cn1 Show InChI InChI=1S/C19H15F2N5O/c1-19(2,27)17-10-24-26-16(9-23-18(26)25-17)11-3-5-14(21)13(7-11)15-6-4-12(20)8-22-15/h3-10,27H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha2 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179920 (2-(7-(3-(3,5-difluoropyridin-2-yl)-4-fluorophenyl)...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncc(F)cc1F Show InChI InChI=1S/C19H14F3N5O/c1-19(2,28)16-9-25-27-15(8-24-18(27)26-16)10-3-4-13(21)12(5-10)17-14(22)6-11(20)7-23-17/h3-9,28H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179917 (2-(7-(4-fluoro-3-(5-fluoropyridin-2-yl)phenyl)imid...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ccc(F)cn1 Show InChI InChI=1S/C19H15F2N5O/c1-19(2,27)17-10-24-26-16(9-23-18(26)25-17)11-3-5-14(21)13(7-11)15-6-4-12(20)8-22-15/h3-10,27H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179922 (4-(2-fluoro-5-(3-(2-hydroxypropan-2-yl)imidazo[1,2...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncncc1C#N Show InChI InChI=1S/C19H14FN7O/c1-19(2,28)16-9-25-27-15(8-23-18(27)26-16)11-3-4-14(20)13(5-11)17-12(6-21)7-22-10-24-17/h3-5,7-10,28H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179921 (2-(7-(4-fluoro-3-(3-fluoropyridin-2-yl)phenyl)imid...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncccc1F Show InChI InChI=1S/C19H15F2N5O/c1-19(2,27)16-10-24-26-15(9-23-18(26)25-16)11-5-6-13(20)12(8-11)17-14(21)4-3-7-22-17/h3-10,27H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.42	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-2/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179920 (2-(7-(3-(3,5-difluoropyridin-2-yl)-4-fluorophenyl)...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncc(F)cc1F Show InChI InChI=1S/C19H14F3N5O/c1-19(2,28)16-9-25-27-15(8-24-18(27)26-16)10-3-4-13(21)12(5-10)17-14(22)6-11(20)7-23-17/h3-9,28H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha2 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179926 (2-(2-fluoro-5-(7-(2-hydroxypropan-2-yl)imidazo[1,2...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncccc1C#N Show InChI InChI=1S/C21H16FN5O/c1-21(2,28)18-7-9-27-17(12-25-20(27)26-18)13-5-6-16(22)15(10-13)19-14(11-23)4-3-8-24-19/h3-10,12,28H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-2/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179849 (2-(3-(4-fluoro-3-(pyridin-3-yl)phenyl)imidazo[1,2-...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1cccnc1 Show InChI InChI=1S/C20H17FN4O/c1-20(2,26)18-7-9-25-17(12-23-19(25)24-18)13-5-6-16(21)15(10-13)14-4-3-8-22-11-14/h3-12,26H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha2 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179915 (2-(3-(3-(3,5-difluoropyridin-2-yl)-4-fluorophenyl)...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncc(F)cc1F Show InChI InChI=1S/C20H15F3N4O/c1-20(2,28)17-5-6-27-16(10-25-19(27)26-17)11-3-4-14(22)13(7-11)18-15(23)8-12(21)9-24-18/h3-10,28H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179849 (2-(3-(4-fluoro-3-(pyridin-3-yl)phenyl)imidazo[1,2-...) Show SMILES CC(C)(O)c1ccn2c(cnc2n1)-c1ccc(F)c(c1)-c1cccnc1 Show InChI InChI=1S/C20H17FN4O/c1-20(2,26)18-7-9-25-17(12-23-19(25)24-18)13-5-6-16(21)15(10-13)14-4-3-8-22-11-14/h3-12,26H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179920 (2-(7-(3-(3,5-difluoropyridin-2-yl)-4-fluorophenyl)...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncc(F)cc1F Show InChI InChI=1S/C19H14F3N5O/c1-19(2,28)16-9-25-27-15(8-24-18(27)26-16)10-3-4-13(21)12(5-10)17-14(22)6-11(20)7-23-17/h3-9,28H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-2/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179916 (2-(2-fluoro-5-(3-(2-hydroxypropan-2-yl)imidazo[1,2...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncccc1C#N Show InChI InChI=1S/C20H15FN6O/c1-20(2,28)17-11-25-27-16(10-24-19(27)26-17)12-5-6-15(21)14(8-12)18-13(9-22)4-3-7-23-18/h3-8,10-11,28H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha2 receptor plus beta3gamma2 expressed in mouse L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
GABA-A receptor; alpha-5/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179916 (2-(2-fluoro-5-(3-(2-hydroxypropan-2-yl)imidazo[1,2...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncccc1C#N Show InChI InChI=1S/C20H15FN6O/c1-20(2,28)17-11-25-27-16(10-24-19(27)26-17)12-5-6-15(21)14(8-12)18-13(9-22)4-3-7-23-18/h3-8,10-11,28H,1-2H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha5 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair
Gamma-aminobutyric acid receptor subunit alpha-3/beta-3/gamma-2 (Homo sapiens (Human))	BDBM50179916 (2-(2-fluoro-5-(3-(2-hydroxypropan-2-yl)imidazo[1,2...) Show SMILES CC(C)(O)c1cnn2c(cnc2n1)-c1ccc(F)c(c1)-c1ncccc1C#N Show InChI InChI=1S/C20H15FN6O/c1-20(2,28)17-11-25-27-16(10-24-19(27)26-17)12-5-6-15(21)14(8-12)18-13(9-22)4-3-7-23-18/h3-8,10-11,28H,1-2H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.53	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp and Dohme Research Laboratories Curated by ChEMBL					Assay Description Displacement of [3H]Ro 15-1788 from recombinant human GABA-Aalpha3 receptor plus beta3gamma2 expressed in L(tk-) cells				Bioorg Med Chem Lett 16: 1477-80 (2006) Article DOI: 10.1016/j.bmcl.2005.12.044 BindingDB Entry DOI: 10.7270/Q2NC60SW
					More data for this Ligand-Target Pair