Found 25 hits Enz. Inhib. hit(s) with all data for entry = 50045825 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Coagulation factor XIII A chain
(Homo sapiens (Human)) | BDBM50083722
(CHEMBL3423198)Show SMILES NC(=O)[C@@H]1O[C@@H]1C(=O)Nc1ccc(Br)c(Cl)c1 |r| Show InChI InChI=1S/C10H8BrClN2O3/c11-5-2-1-4(3-6(5)12)14-10(16)8-7(17-8)9(13)15/h1-3,7-8H,(H2,13,15)(H,14,16)/t7-,8+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio... |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Coagulation factor XIII A chain
(Homo sapiens (Human)) | BDBM50083725
(CHEMBL3423195)Show SMILES NC(=O)[C@H]1O[C@H]1C(=O)Nc1cccc(Oc2ccccc2)c1 |r| Show InChI InChI=1S/C16H14N2O4/c17-15(19)13-14(22-13)16(20)18-10-5-4-8-12(9-10)21-11-6-2-1-3-7-11/h1-9,13-14H,(H2,17,19)(H,18,20)/t13-,14+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio... |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Protein-glutamine gamma-glutamyltransferase 2
(Homo sapiens (Human)) | BDBM50083722
(CHEMBL3423198)Show SMILES NC(=O)[C@@H]1O[C@@H]1C(=O)Nc1ccc(Br)c(Cl)c1 |r| Show InChI InChI=1S/C10H8BrClN2O3/c11-5-2-1-4(3-6(5)12)14-10(16)8-7(17-8)9(13)15/h1-3,7-8H,(H2,13,15)(H,14,16)/t7-,8+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 9.60 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of transglutaminase 2 (unknown origin) |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Protein-glutamine gamma-glutamyltransferase 2
(Homo sapiens (Human)) | BDBM50083728
(CHEMBL3423193)Show SMILES NC(=O)[C@H]1O[C@H]1C(=O)Nc1ccc(Oc2ccccc2)cc1 |r| Show InChI InChI=1S/C16H14N2O4/c17-15(19)13-14(22-13)16(20)18-10-6-8-12(9-7-10)21-11-4-2-1-3-5-11/h1-9,13-14H,(H2,17,19)(H,18,20)/t13-,14+/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 46 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of transglutaminase 2 (unknown origin) |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Protein-glutamine gamma-glutamyltransferase 2
(Homo sapiens (Human)) | BDBM50083718
(CHEMBL3423202)Show SMILES NC(=O)[C@@H]1O[C@@H]1C(=O)Nc1ccc(Oc2ccc(N)cc2)cc1 |r| Show InChI InChI=1S/C16H15N3O4/c17-9-1-5-11(6-2-9)22-12-7-3-10(4-8-12)19-16(21)14-13(23-14)15(18)20/h1-8,13-14H,17H2,(H2,18,20)(H,19,21)/t13-,14+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of transglutaminase 2 (unknown origin) |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Protein-glutamine gamma-glutamyltransferase 2
(Homo sapiens (Human)) | BDBM50083726
(CHEMBL3423194)Show InChI InChI=1S/C10H9ClN2O3/c11-5-2-1-3-6(4-5)13-10(15)8-7(16-8)9(12)14/h1-4,7-8H,(H2,12,14)(H,13,15)/t7-,8+/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of transglutaminase 2 (unknown origin) |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Coagulation factor XIII A chain
(Homo sapiens (Human)) | BDBM50083726
(CHEMBL3423194)Show InChI InChI=1S/C10H9ClN2O3/c11-5-2-1-3-6(4-5)13-10(15)8-7(16-8)9(12)14/h1-4,7-8H,(H2,12,14)(H,13,15)/t7-,8+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 48 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio... |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Protein-glutamine gamma-glutamyltransferase 2
(Homo sapiens (Human)) | BDBM50083725
(CHEMBL3423195)Show SMILES NC(=O)[C@H]1O[C@H]1C(=O)Nc1cccc(Oc2ccccc2)c1 |r| Show InChI InChI=1S/C16H14N2O4/c17-15(19)13-14(22-13)16(20)18-10-5-4-8-12(9-10)21-11-6-2-1-3-7-11/h1-9,13-14H,(H2,17,19)(H,18,20)/t13-,14+/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 50 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of transglutaminase 2 (unknown origin) |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Coagulation factor XIII A chain
(Homo sapiens (Human)) | BDBM50083728
(CHEMBL3423193)Show SMILES NC(=O)[C@H]1O[C@H]1C(=O)Nc1ccc(Oc2ccccc2)cc1 |r| Show InChI InChI=1S/C16H14N2O4/c17-15(19)13-14(22-13)16(20)18-10-6-8-12(9-7-10)21-11-4-2-1-3-5-11/h1-9,13-14H,(H2,17,19)(H,18,20)/t13-,14+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio... |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Protein-glutamine gamma-glutamyltransferase 2
(Homo sapiens (Human)) | BDBM50083723
(CHEMBL3423197)Show SMILES NC(=O)[C@@H]1O[C@@H]1C(=O)Nc1ccc(Br)cc1 |r| Show InChI InChI=1S/C10H9BrN2O3/c11-5-1-3-6(4-2-5)13-10(15)8-7(16-8)9(12)14/h1-4,7-8H,(H2,12,14)(H,13,15)/t7-,8+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 57 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of transglutaminase 2 (unknown origin) |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Coagulation factor XIII A chain
(Homo sapiens (Human)) | BDBM50083718
(CHEMBL3423202)Show SMILES NC(=O)[C@@H]1O[C@@H]1C(=O)Nc1ccc(Oc2ccc(N)cc2)cc1 |r| Show InChI InChI=1S/C16H15N3O4/c17-9-1-5-11(6-2-9)22-12-7-3-10(4-8-12)19-16(21)14-13(23-14)15(18)20/h1-8,13-14H,17H2,(H2,18,20)(H,19,21)/t13-,14+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 86 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio... |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Protein-glutamine gamma-glutamyltransferase 2
(Homo sapiens (Human)) | BDBM50083720
(CHEMBL3423200)Show SMILES NC(=O)[C@@H]1O[C@@H]1C(=O)Nc1ccc(CCNS(=O)(=O)c2ccccc2[N+]([O-])=O)cc1 |r| Show InChI InChI=1S/C18H18N4O7S/c19-17(23)15-16(29-15)18(24)21-12-7-5-11(6-8-12)9-10-20-30(27,28)14-4-2-1-3-13(14)22(25)26/h1-8,15-16,20H,9-10H2,(H2,19,23)(H,21,24)/t15-,16+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 88 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of transglutaminase 2 (unknown origin) |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Coagulation factor XIII A chain
(Homo sapiens (Human)) | BDBM50083720
(CHEMBL3423200)Show SMILES NC(=O)[C@@H]1O[C@@H]1C(=O)Nc1ccc(CCNS(=O)(=O)c2ccccc2[N+]([O-])=O)cc1 |r| Show InChI InChI=1S/C18H18N4O7S/c19-17(23)15-16(29-15)18(24)21-12-7-5-11(6-8-12)9-10-20-30(27,28)14-4-2-1-3-13(14)22(25)26/h1-8,15-16,20H,9-10H2,(H2,19,23)(H,21,24)/t15-,16+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 90 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio... |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Coagulation factor XIII A chain
(Homo sapiens (Human)) | BDBM50083717
(CHEMBL3423203)Show SMILES NC(=O)[C@@H]1O[C@@H]1C(=O)Nc1ccc(Oc2ccc(NC(=O)c3ccc(F)cc3)cc2)cc1 |r| Show InChI InChI=1S/C23H18FN3O5/c24-14-3-1-13(2-4-14)22(29)26-15-5-9-17(10-6-15)31-18-11-7-16(8-12-18)27-23(30)20-19(32-20)21(25)28/h1-12,19-20H,(H2,25,28)(H,26,29)(H,27,30)/t19-,20+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio... |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Coagulation factor XIII A chain
(Homo sapiens (Human)) | BDBM50083721
(CHEMBL3423199)Show InChI InChI=1S/C12H14N2O3/c1-6-3-4-8(5-7(6)2)14-12(16)10-9(17-10)11(13)15/h3-5,9-10H,1-2H3,(H2,13,15)(H,14,16)/t9-,10+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio... |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Coagulation factor XIII A chain
(Homo sapiens (Human)) | BDBM50083723
(CHEMBL3423197)Show SMILES NC(=O)[C@@H]1O[C@@H]1C(=O)Nc1ccc(Br)cc1 |r| Show InChI InChI=1S/C10H9BrN2O3/c11-5-1-3-6(4-2-5)13-10(15)8-7(16-8)9(12)14/h1-4,7-8H,(H2,12,14)(H,13,15)/t7-,8+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio... |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Protein-glutamine gamma-glutamyltransferase 2
(Homo sapiens (Human)) | BDBM50083721
(CHEMBL3423199)Show InChI InChI=1S/C12H14N2O3/c1-6-3-4-8(5-7(6)2)14-12(16)10-9(17-10)11(13)15/h3-5,9-10H,1-2H3,(H2,13,15)(H,14,16)/t9-,10+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of transglutaminase 2 (unknown origin) |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Protein-glutamine gamma-glutamyltransferase 2
(Homo sapiens (Human)) | BDBM50083759
(CHEMBL3423192)Show SMILES CCCCc1ccc(NC(=O)[C@@H]2O[C@@H]2C(N)=O)cc1 |r| Show InChI InChI=1S/C14H18N2O3/c1-2-3-4-9-5-7-10(8-6-9)16-14(18)12-11(19-12)13(15)17/h5-8,11-12H,2-4H2,1H3,(H2,15,17)(H,16,18)/t11-,12+/m0/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of transglutaminase 2 (unknown origin) |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Protein-glutamine gamma-glutamyltransferase 2
(Homo sapiens (Human)) | BDBM50083717
(CHEMBL3423203)Show SMILES NC(=O)[C@@H]1O[C@@H]1C(=O)Nc1ccc(Oc2ccc(NC(=O)c3ccc(F)cc3)cc2)cc1 |r| Show InChI InChI=1S/C23H18FN3O5/c24-14-3-1-13(2-4-14)22(29)26-15-5-9-17(10-6-15)31-18-11-7-16(8-12-18)27-23(30)20-19(32-20)21(25)28/h1-12,19-20H,(H2,25,28)(H,26,29)(H,27,30)/t19-,20+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 150 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of transglutaminase 2 (unknown origin) |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Coagulation factor XIII A chain
(Homo sapiens (Human)) | BDBM50083759
(CHEMBL3423192)Show SMILES CCCCc1ccc(NC(=O)[C@@H]2O[C@@H]2C(N)=O)cc1 |r| Show InChI InChI=1S/C14H18N2O3/c1-2-3-4-9-5-7-10(8-6-9)16-14(18)12-11(19-12)13(15)17/h5-8,11-12H,2-4H2,1H3,(H2,15,17)(H,16,18)/t11-,12+/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio... |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Coagulation factor XIII A chain
(Homo sapiens (Human)) | BDBM50083719
(CHEMBL3423201)Show SMILES NC(=O)[C@@H]1O[C@@H]1C(=O)Nc1ccc(Oc2ccc(cc2)[N+]([O-])=O)cc1 |r| Show InChI InChI=1S/C16H13N3O6/c17-15(20)13-14(25-13)16(21)18-9-1-5-11(6-2-9)24-12-7-3-10(4-8-12)19(22)23/h1-8,13-14H,(H2,17,20)(H,18,21)/t13-,14+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 430 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio... |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Coagulation factor XIII A chain
(Homo sapiens (Human)) | BDBM50083724
(CHEMBL3423196)Show InChI InChI=1S/C10H10N2O3/c11-9(13)7-8(15-7)10(14)12-6-4-2-1-3-5-6/h1-5,7-8H,(H2,11,13)(H,12,14)/t7-,8+/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 720 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio... |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Protein-glutamine gamma-glutamyltransferase 2
(Homo sapiens (Human)) | BDBM50083724
(CHEMBL3423196)Show InChI InChI=1S/C10H10N2O3/c11-9(13)7-8(15-7)10(14)12-6-4-2-1-3-5-6/h1-5,7-8H,(H2,11,13)(H,12,14)/t7-,8+/m1/s1 | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL KEGG PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of transglutaminase 2 (unknown origin) |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Coagulation factor XIII A chain
(Homo sapiens (Human)) | BDBM50009248
((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)Show InChI InChI=1S/C12H17NO3/c1-2-3-4-5-6-7-8-9(14)10-11(16-10)12(13)15/h2-3,5-6,10-11H,4,7-8H2,1H3,(H2,13,15)/b3-2+,6-5+/t10-,11-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | 4.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of thrombin-activated F13-A (unknown origin) in plasma assessed as inhibition of fibrin clot formation after 7 mins by biotin incorporatio... |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |
Coagulation factor XIII A chain
(Homo sapiens (Human)) | BDBM50009248
((2R,3S)-3-((4E,7E)-Nona-4,7-dienoyl)-oxirane-2-car...)Show InChI InChI=1S/C12H17NO3/c1-2-3-4-5-6-7-8-9(14)10-11(16-10)12(13)15/h2-3,5-6,10-11H,4,7-8H2,1H3,(H2,13,15)/b3-2+,6-5+/t10-,11-/m1/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | 1.80E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Leeds
Curated by ChEMBL
| Assay Description Inhibition of F13-A in human plasma assessed as inhibition of fibrin clot formation by biotin incorporation assay in presence of 1 mM reduced GSH |
Eur J Med Chem 98: 49-53 (2015)
Article DOI: 10.1016/j.ejmech.2015.05.019 BindingDB Entry DOI: 10.7270/Q261121G |
More data for this Ligand-Target Pair | |