Compile Data Set for Download or QSAR

Found 63 hits Enz. Inhib. hit(s) with all data for entry = 50017398   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50181745 (3-[(2-methyl-4-thiazolyl)ethynyl]benzonitrile | CH...) Show SMILES Cc1nc(cs1)C#Cc1cccc(c1)C#N Show InChI InChI=1S/C13H8N2S/c1-10-15-13(9-16-10)6-5-11-3-2-4-12(7-11)8-14/h2-4,7,9H,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from mGluR5 in rat brain membranes				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181745 (3-[(2-methyl-4-thiazolyl)ethynyl]benzonitrile | CH...) Show SMILES Cc1nc(cs1)C#Cc1cccc(c1)C#N Show InChI InChI=1S/C13H8N2S/c1-10-15-13(9-16-10)6-5-11-3-2-4-12(7-11)8-14/h2-4,7,9H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from cloned human mGluR5 transfected in HEK293-T cells				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM50181753 (3-[(2-methyl-4-thiazolyl)ethynyl]-5-vinylpyridine ...) Show SMILES Cc1nc(cs1)C#Cc1cncc(C=C)c1 Show InChI InChI=1S/C13H10N2S/c1-3-11-6-12(8-14-7-11)4-5-13-9-16-10(2)15-13/h3,6-9H,1H2,2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from mGluR5 in rat brain membranes				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181753 (3-[(2-methyl-4-thiazolyl)ethynyl]-5-vinylpyridine ...) Show SMILES Cc1nc(cs1)C#Cc1cncc(C=C)c1 Show InChI InChI=1S/C13H10N2S/c1-3-11-6-12(8-14-7-11)4-5-13-9-16-10(2)15-13/h3,6-9H,1H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.00	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Displacement of [3H]MPEP from cloned human mGluR5 transfected in HEK293-T cells				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181745 (3-[(2-methyl-4-thiazolyl)ethynyl]benzonitrile | CH...) Show SMILES Cc1nc(cs1)C#Cc1cccc(c1)C#N Show InChI InChI=1S/C13H8N2S/c1-10-15-13(9-16-10)6-5-11-3-2-4-12(7-11)8-14/h2-4,7,9H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.940	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181753 (3-[(2-methyl-4-thiazolyl)ethynyl]-5-vinylpyridine ...) Show SMILES Cc1nc(cs1)C#Cc1cncc(C=C)c1 Show InChI InChI=1S/C13H10N2S/c1-3-11-6-12(8-14-7-11)4-5-13-9-16-10(2)15-13/h3,6-9H,1H2,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.01	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181778 (2-(4-fluorophenyl)-5-[(2-methyl-4-thiazolyl)ethyny...) Show SMILES Cc1nc(cs1)C#Cc1ccc(nc1)-c1ccc(F)cc1 Show InChI InChI=1S/C17H11FN2S/c1-12-20-16(11-21-12)8-2-13-3-9-17(19-10-13)14-4-6-15(18)7-5-14/h3-7,9-11H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10.2	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181785 (3-ethynyl-5-[(2-methyl-4-thiazolyl)ethynyl]pyridin...) Show SMILES Cc1nc(cs1)C#Cc1cncc(c1)C#C Show InChI InChI=1S/C13H8N2S/c1-3-11-6-12(8-14-7-11)4-5-13-9-16-10(2)15-13/h1,6-9H,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19.2	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181748 (4-(2-(3-fluorophenyl)ethynyl)-2-methylthiazole | C...) Show SMILES Cc1nc(cs1)C#Cc1cccc(F)c1 Show InChI InChI=1S/C12H8FNS/c1-9-14-12(8-15-9)6-5-10-3-2-4-11(13)7-10/h2-4,7-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181759 (4-(3,5-difluorophenylethynyl)-2-methylthiazole | C...) Show SMILES Cc1nc(cs1)C#Cc1cc(F)cc(F)c1 Show InChI InChI=1S/C12H7F2NS/c1-8-15-12(7-16-8)3-2-9-4-10(13)6-11(14)5-9/h4-7H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25.3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181749 (4-(2-methoxyphenylethynyl)-2-methylthiazole | CHEM...) Show SMILES COc1ccccc1C#Cc1csc(C)n1 Show InChI InChI=1S/C13H11NOS/c1-10-14-12(9-16-10)8-7-11-5-3-4-6-13(11)15-2/h3-6,9H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	36.3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50084137 (2-Methyl-6-(phenylethynyl)pyridine | 2-Methyl-6-ph...) Show SMILES Cc1cccc(n1)C#Cc1ccccc1 Show InChI InChI=1S/C14H11N/c1-12-6-5-9-14(15-12)11-10-13-7-3-2-4-8-13/h2-9H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181742 (2-chloro-3-[(2-methyl-4-thiazolyl)ethynyl]pyridine...) Show SMILES Cc1nc(cs1)C#Cc1cccnc1Cl Show InChI InChI=1S/C11H7ClN2S/c1-8-14-10(7-15-8)5-4-9-3-2-6-13-11(9)12/h2-3,6-7H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	45.5	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181739 (4-(3-methoxyphenylethynyl)-2-methylthiazole | CHEM...) Show SMILES COc1cccc(c1)C#Cc1csc(C)n1 Show InChI InChI=1S/C13H11NOS/c1-10-14-12(9-16-10)7-6-11-4-3-5-13(8-11)15-2/h3-5,8-9H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181777 (3-bromo-5-[(2-methyl-4-thiazolyl)ethynyl]pyridine ...) Show SMILES Cc1nc(cs1)C#Cc1cncc(Br)c1 Show InChI InChI=1S/C11H7BrN2S/c1-8-14-11(7-15-8)3-2-9-4-10(12)6-13-5-9/h4-7H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181746 (3-[5-[(2-methyl-4-thiazolyl)ethynyl]-3-pyridyl]-2-...) Show SMILES Cc1nc(cs1)C#Cc1cncc(c1)C#CCO Show InChI InChI=1S/C14H10N2OS/c1-11-16-14(10-18-11)5-4-13-7-12(3-2-6-17)8-15-9-13/h7-10,17H,6H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	68.6	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181770 (4-(3-fluorophenylethynyl)-2-thiazolylamine | CHEMB...) Show SMILES Nc1nc(cs1)C#Cc1cccc(F)c1 Show InChI InChI=1S/C11H7FN2S/c12-9-3-1-2-8(6-9)4-5-10-7-15-11(13)14-10/h1-3,6-7H,(H2,13,14)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78.6	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50149802 (2-Methyl-4-m-tolylethynyl-thiazole | 2-methyl-4-(m...) Show SMILES Cc1nc(cs1)C#Cc1cccc(C)c1 Show InChI InChI=1S/C13H11NS/c1-10-4-3-5-12(8-10)6-7-13-9-15-11(2)14-13/h3-5,8-9H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	82.6	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181779 (4-(3-chlorophenylethynyl)-2-methylthiazole | CHEMB...) Show SMILES Cc1nc(cs1)C#Cc1cccc(Cl)c1 Show InChI InChI=1S/C12H8ClNS/c1-9-14-12(8-15-9)6-5-10-3-2-4-11(13)7-10/h2-4,7-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181780 (4-(2-fluorophenylethynyl)-2-methylthiazole | CHEMB...) Show SMILES Cc1nc(cs1)C#Cc1ccccc1F Show InChI InChI=1S/C12H8FNS/c1-9-14-11(8-15-9)7-6-10-4-2-3-5-12(10)13/h2-5,8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181789 (3-(4-fluorophenyl)-5-[(2-methyl-4-thiazolyl)ethyny...) Show SMILES Cc1nc(cs1)C#Cc1cncc(c1)-c1ccc(F)cc1 Show InChI InChI=1S/C17H11FN2S/c1-12-20-17(11-21-12)7-2-13-8-15(10-19-9-13)14-3-5-16(18)6-4-14/h3-6,8-11H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181760 (2-ethynyl-3-[(2-methyl-4-thiazolyl)ethynyl]pyridin...) Show SMILES Cc1nc(cs1)C#Cc1cccnc1C#C Show InChI InChI=1S/C13H8N2S/c1-3-13-11(5-4-8-14-13)6-7-12-9-16-10(2)15-12/h1,4-5,8-9H,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	192	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181738 (3-(4-methoxyphenyl)-5-[(2-methyl-4-thiazolyl)ethyn...) Show SMILES COc1ccc(cc1)-c1cncc(c1)C#Cc1csc(C)n1 Show InChI InChI=1S/C18H14N2OS/c1-13-20-17(12-22-13)6-3-14-9-16(11-19-10-14)15-4-7-18(21-2)8-5-15/h4-5,7-12H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	225	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181740 (2-methoxy-3-[(2-methyl-4-thiazolyl)ethynyl]pyridin...) Show SMILES COc1ncccc1C#Cc1csc(C)n1 Show InChI InChI=1S/C12H10N2OS/c1-9-14-11(8-16-9)6-5-10-4-3-7-13-12(10)15-2/h3-4,7-8H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	228	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181771 (2-methyl-4-[[3-(trifluoromethoxy)phenyl]ethynyl]th...) Show SMILES Cc1nc(cs1)C#Cc1cccc(OC(F)(F)F)c1 Show InChI InChI=1S/C13H8F3NOS/c1-9-17-11(8-19-9)6-5-10-3-2-4-12(7-10)18-13(14,15)16/h2-4,7-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	266	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181788 (2-methyl-4-(3-thienylethynyl)thiazole | CHEMBL2026...) Show SMILES Cc1nc(cs1)C#Cc1ccsc1 Show InChI InChI=1S/C10H7NS2/c1-8-11-10(7-13-8)3-2-9-4-5-12-6-9/h4-7H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	337	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181754 (2-methyl-4-[[3-(trifluoromethyl)phenyl]ethynyl]thi...) Show SMILES Cc1nc(cs1)C#Cc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C13H8F3NS/c1-9-17-12(8-18-9)6-5-10-3-2-4-11(7-10)13(14,15)16/h2-4,7-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	413	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181755 (2-methoxy-5-(2-(2-methylthiazol-4-yl)ethynyl)pyrid...) Show SMILES COc1ccc(cn1)C#Cc1csc(C)n1 Show InChI InChI=1S/C12H10N2OS/c1-9-14-11(8-16-9)5-3-10-4-6-12(15-2)13-7-10/h4,6-8H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	426	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50122758 (2-methyl-4-(pyridin-3-ylethynyl)thiazole | 3-(2-(2...) Show SMILES Cc1nc(cs1)C#Cc1cccnc1 Show InChI InChI=1S/C11H8N2S/c1-9-13-11(8-14-9)5-4-10-3-2-6-12-7-10/h2-3,6-8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	462	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181768 (2-methyl-4-(2-thienylethynyl)thiazole | CHEMBL2023...) Show SMILES Cc1nc(cs1)C#Cc1cccs1 Show InChI InChI=1S/C10H7NS2/c1-8-11-9(7-13-8)4-5-10-3-2-6-12-10/h2-3,6-7H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	475	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181781 (2-bromo-4-(3-fluorophenylethynyl)thiazole | CHEMBL...) Show SMILES Fc1cccc(c1)C#Cc1csc(Br)n1 Show InChI InChI=1S/C11H5BrFNS/c12-11-14-10(7-15-11)5-4-8-2-1-3-9(13)6-8/h1-3,6-7H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	526	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181784 (3-[(2-methyl-4-thiazolyl)ethynyl]phenol | CHEMBL20...) Show SMILES Cc1nc(cs1)C#Cc1cccc(O)c1 Show InChI InChI=1S/C12H9NOS/c1-9-13-11(8-15-9)6-5-10-3-2-4-12(14)7-10/h2-4,7-8,14H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	654	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181787 (3-[(2,5-dimethyl-4-thiazolyl)ethynyl]pyridine | CH...) Show SMILES Cc1nc(C#Cc2cccnc2)c(C)s1 Show InChI InChI=1S/C12H10N2S/c1-9-12(14-10(2)15-9)6-5-11-4-3-7-13-8-11/h3-4,7-8H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	698	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181757 (4-(3-pyridylethynyl)-2-thiazolylamine | CHEMBL3810...) Show SMILES Nc1nc(cs1)C#Cc1cccnc1 Show InChI InChI=1S/C10H7N3S/c11-10-13-9(7-14-10)4-3-8-2-1-5-12-6-8/h1-2,5-7H,(H2,11,13)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	789	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181750 (2-fluoro-5-[(2-methyl-4-thiazolyl)ethynyl]pyridine...) Show SMILES Cc1nc(cs1)C#Cc1ccc(F)nc1 Show InChI InChI=1S/C11H7FN2S/c1-8-14-10(7-15-8)4-2-9-3-5-11(12)13-6-9/h3,5-7H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	833	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181772 (5-[(2-methyl-4-thiazolyl)ethynyl]pyrimidine | CHEM...) Show SMILES Cc1nc(cs1)C#Cc1cncnc1 Show InChI InChI=1S/C10H7N3S/c1-8-13-10(6-14-8)3-2-9-4-11-7-12-5-9/h4-7H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	946	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181774 (3-[(2-methyl-4-thiazolyl)ethynyl]benzamide | CHEMB...) Show SMILES Cc1nc(cs1)C#Cc1cccc(c1)C(N)=O Show InChI InChI=1S/C13H10N2OS/c1-9-15-12(8-17-9)6-5-10-3-2-4-11(7-10)13(14)16/h2-4,7-8H,1H3,(H2,14,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181769 (5-fluoro-2-[(2-methyl-4-thiazolyl)ethynyl]pyridine...) Show SMILES Cc1nc(cs1)C#Cc1ccc(F)cn1 Show InChI InChI=1S/C11H7FN2S/c1-8-14-11(7-15-8)5-4-10-3-2-9(12)6-13-10/h2-3,6-7H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181786 (3-[(5-ethyl-2-methyl-4-thiazolyl)ethynyl]pyridine ...) Show SMILES CCc1sc(C)nc1C#Cc1cccnc1 Show InChI InChI=1S/C13H12N2S/c1-3-13-12(15-10(2)16-13)7-6-11-5-4-8-14-9-11/h4-5,8-9H,3H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181736 (2-[(2-methyl-4-thiazolyl)ethynyl]pyrazine | CHEMBL...) Show SMILES Cc1nc(cs1)C#Cc1cnccn1 Show InChI InChI=1S/C10H7N3S/c1-8-13-10(7-14-8)3-2-9-6-11-4-5-12-9/h4-7H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.83E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181776 (CHEMBL381482 | N-[4-(3-pyridylethynyl)-2-thiazolyl...) Show SMILES CC(=O)Nc1nc(cs1)C#Cc1cccnc1 Show InChI InChI=1S/C12H9N3OS/c1-9(16)14-12-15-11(8-17-12)5-4-10-3-2-6-13-7-10/h2-3,6-8H,1H3,(H,14,15,16)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181767 (CHEMBL202051 | N-[3-[(2-methyl-4-thiazolyl)ethynyl...) Show SMILES CC(=O)Nc1cccc(c1)C#Cc1csc(C)n1 Show InChI InChI=1S/C14H12N2OS/c1-10(17)15-13-5-3-4-12(8-13)6-7-14-9-18-11(2)16-14/h3-5,8-9H,1-2H3,(H,15,17)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181741 (CHEMBL201774 | methanesulfonic acid 5-[(2-methyl-4...) Show SMILES Cc1nc(cs1)C#Cc1ccc(OS(C)(=O)=O)nc1 Show InChI InChI=1S/C12H10N2O3S2/c1-9-14-11(8-18-9)5-3-10-4-6-12(13-7-10)17-19(2,15)16/h4,6-8H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.34E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181773 (2-ethynyl-4-(3-fluorophenylethynyl)thiazole | CHEM...) Show SMILES Fc1cccc(c1)C#Cc1csc(n1)C#C Show InChI InChI=1S/C13H6FNS/c1-2-13-15-12(9-16-13)7-6-10-4-3-5-11(14)8-10/h1,3-5,8-9H	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.92E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181766 (3-ethynyl-5-[(2-methyl-4-thiazolyl)ethynyl]pyridin...) Show SMILES Cc1nc(cs1)C#Cc1ccc(nc1)C#C Show InChI InChI=1S/C13H8N2S/c1-3-12-6-4-11(8-14-12)5-7-13-9-16-10(2)15-13/h1,4,6,8-9H,2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.95E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181765 (4-(2-(4-fluorophenyl)ethynyl)-2-methylthiazole | C...) Show SMILES Cc1nc(cs1)C#Cc1ccc(F)cc1 Show InChI InChI=1S/C12H8FNS/c1-9-14-12(8-15-9)7-4-10-2-5-11(13)6-3-10/h2-3,5-6,8H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.97E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181762 ((E)-3-[2-(2-methyl-4-thiazolyl)vinyl]pyridine | CH...) Show SMILES Cc1nc(\C=C\c2cccnc2)cs1 Show InChI InChI=1S/C11H10N2S/c1-9-13-11(8-14-9)5-4-10-3-2-6-12-7-10/h2-8H,1H3/b5-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181737 (CHEMBL202041 | N-[4-(3-pyridylethynyl)-2-thiazolyl...) Show SMILES C(Nc1nc(cs1)C#Cc1cccnc1)c1ccccc1 Show InChI InChI=1S/C17H13N3S/c1-2-5-14(6-3-1)12-19-17-20-16(13-21-17)9-8-15-7-4-10-18-11-15/h1-7,10-11,13H,12H2,(H,19,20)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181763 (2-chloro-5-[(2-methyl-4-thiazolyl)ethynyl]pyridine...) Show SMILES Cc1nc(cs1)C#Cc1ccc(Cl)nc1 Show InChI InChI=1S/C11H7ClN2S/c1-8-14-10(7-15-8)4-2-9-3-5-11(12)13-6-9/h3,5-7H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 5 (Homo sapiens (Human))	BDBM50181761 (6-[(2-methyl-4-thiazolyl)ethynyl]quinoxaline | CHE...) Show SMILES Cc1nc(cs1)C#Cc1ccc2nccnc2c1 Show InChI InChI=1S/C14H9N3S/c1-10-17-12(9-18-10)4-2-11-3-5-13-14(8-11)16-7-6-15-13/h3,5-9H,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Illinois at Chicago Curated by ChEMBL					Assay Description Activity in agonist-induced phosphoinositide hydrolysis in CHO cells expressing mGluR5a				J Med Chem 49: 1080-100 (2006) Article DOI: 10.1021/jm050570f BindingDB Entry DOI: 10.7270/Q27S7NC5
					More data for this Ligand-Target Pair

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