Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM50090908 (CHEBI:67291 | CHEMBL1774404) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiba University Curated by ChEMBL | Assay Description Activation of GSK-3beta in HEK293 cells assessed as suppression of TCF/beta-catenin transcriptional activity after 24 hrs by SuperTOPFlash reporter g... | J Nat Prod 78: 1139-46 (2015) Article DOI: 10.1021/acs.jnatprod.5b00153 BindingDB Entry DOI: 10.7270/Q2P270VC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM50090907 (CHEBI:66041 | CHEMBL444160) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiba University Curated by ChEMBL | Assay Description Activation of GSK-3beta in HEK293 cells assessed as suppression of TCF/beta-catenin transcriptional activity after 24 hrs by SuperTOPFlash reporter g... | J Nat Prod 78: 1139-46 (2015) Article DOI: 10.1021/acs.jnatprod.5b00153 BindingDB Entry DOI: 10.7270/Q2P270VC | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glycogen synthase kinase-3 beta (Homo sapiens (Human)) | BDBM50090909 (CHEMBL3120496) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.16E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Chiba University Curated by ChEMBL | Assay Description Activation of GSK-3beta in HEK293 cells assessed as suppression of TCF/beta-catenin transcriptional activity after 24 hrs by SuperTOPFlash reporter g... | J Nat Prod 78: 1139-46 (2015) Article DOI: 10.1021/acs.jnatprod.5b00153 BindingDB Entry DOI: 10.7270/Q2P270VC | |||||||||||
More data for this Ligand-Target Pair |