Compile Data Set for Download or QSAR

Found 6 hits Enz. Inhib. hit(s) with all data for entry = 50046046   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prolyl 4-hydroxylase subunit alpha-1 (Homo sapiens (Human))	BDBM50042876 (CHEMBL332005 | [2,2']Bipyridinyl-5,5'-dicarboxylic...) Show SMILES OC(=O)c1ccc(nc1)-c1ccc(cn1)C(O)=O Show InChI InChI=1S/C12H8N2O4/c15-11(16)7-1-3-9(13-5-7)10-4-2-8(6-14-10)12(17)18/h1-6H,(H,15,16)(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	7.8	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...				Bioorg Med Chem 23: 3081-90 (2015) Article DOI: 10.1016/j.bmc.2015.05.003 BindingDB Entry DOI: 10.7270/Q2N01897
					More data for this Ligand-Target Pair
Prolyl 4-hydroxylase subunit alpha-1 (Homo sapiens (Human))	BDBM50092609 (CHEMBL3586252) Show SMILES OC(=O)c1ccc(nc1)-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C12H8N2O4/c15-11(16)7-3-4-13-10(5-7)9-2-1-8(6-14-9)12(17)18/h1-6H,(H,15,16)(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	7.8	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...				Bioorg Med Chem 23: 3081-90 (2015) Article DOI: 10.1016/j.bmc.2015.05.003 BindingDB Entry DOI: 10.7270/Q2N01897
					More data for this Ligand-Target Pair
Prolyl 4-hydroxylase subunit alpha-1 (Homo sapiens (Human))	BDBM26114 (CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...) Show SMILES OC(=O)c1ccc(nc1)C(O)=O Show InChI InChI=1S/C7H5NO4/c9-6(10)4-1-2-5(7(11)12)8-3-4/h1-3H,(H,9,10)(H,11,12)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	Article PubMed	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.8	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...				Bioorg Med Chem 23: 3081-90 (2015) Article DOI: 10.1016/j.bmc.2015.05.003 BindingDB Entry DOI: 10.7270/Q2N01897
					More data for this Ligand-Target Pair
Prolyl 4-hydroxylase subunit alpha-1 (Homo sapiens (Human))	BDBM50042876 (CHEMBL332005 | [2,2']Bipyridinyl-5,5'-dicarboxylic...) Show SMILES OC(=O)c1ccc(nc1)-c1ccc(cn1)C(O)=O Show InChI InChI=1S/C12H8N2O4/c15-11(16)7-1-3-9(13-5-7)10-4-2-8(6-14-10)12(17)18/h1-6H,(H,15,16)(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	7.8	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...				Bioorg Med Chem 23: 3081-90 (2015) Article DOI: 10.1016/j.bmc.2015.05.003 BindingDB Entry DOI: 10.7270/Q2N01897
					More data for this Ligand-Target Pair
Prolyl 4-hydroxylase subunit alpha-1 (Homo sapiens (Human))	BDBM50092609 (CHEMBL3586252) Show SMILES OC(=O)c1ccc(nc1)-c1cc(ccn1)C(O)=O Show InChI InChI=1S/C12H8N2O4/c15-11(16)7-3-4-13-10(5-7)9-2-1-8(6-14-9)12(17)18/h1-6H,(H,15,16)(H,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	7.8	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...				Bioorg Med Chem 23: 3081-90 (2015) Article DOI: 10.1016/j.bmc.2015.05.003 BindingDB Entry DOI: 10.7270/Q2N01897
					More data for this Ligand-Target Pair
Prolyl 4-hydroxylase subunit alpha-1 (Homo sapiens (Human))	BDBM26114 (CHEMBL88972 | pyridine carboxylate, 6b | pyridine-...) Show SMILES OC(=O)c1ccc(nc1)C(O)=O Show InChI InChI=1S/C7H5NO4/c9-6(10)4-1-2-5(7(11)12)8-3-4/h1-3H,(H,9,10)(H,11,12)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	7.8	n/a
University of Wisconsin-Madison Curated by ChEMBL					Assay Description Inhibition of human human recombinant CP4H1 expressed in Escherichia coli Origami B(DE3) pre-incubated for 2 mins followed by alpha-ketoglutarate add...				Bioorg Med Chem 23: 3081-90 (2015) Article DOI: 10.1016/j.bmc.2015.05.003 BindingDB Entry DOI: 10.7270/Q2N01897
					More data for this Ligand-Target Pair