Found 195 hits Enz. Inhib. hit(s) with all data for entry = 50046178 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50097869
(CHEMBL3589662)Show InChI InChI=1S/C16H9IN2O2/c17-10-6-3-5-9-12-14(19-13(9)10)8-4-1-2-7-11(8)18-15(12)16(20)21/h1-7,19H,(H,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human)) | BDBM50097868
(CHEMBL3589661)Show InChI InChI=1S/C16H9BrN2O2/c17-10-6-3-5-9-12-14(19-13(9)10)8-4-1-2-7-11(8)18-15(12)16(20)21/h1-7,19H,(H,20,21) | PDB MMDB
NCI pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 16 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK2 expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50097855
(CHEMBL3589666)Show InChI InChI=1S/C17H11BrN2O3/c1-23-8-5-6-9-12(7-8)19-16(17(21)22)13-10-3-2-4-11(18)14(10)20-15(9)13/h2-7,20H,1H3,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 18 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50097868
(CHEMBL3589661)Show InChI InChI=1S/C16H9BrN2O2/c17-10-6-3-5-9-12-14(19-13(9)10)8-4-1-2-7-11(8)18-15(12)16(20)21/h1-7,19H,(H,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50097855
(CHEMBL3589666)Show InChI InChI=1S/C17H11BrN2O3/c1-23-8-5-6-9-12(7-8)19-16(17(21)22)13-10-3-2-4-11(18)14(10)20-15(9)13/h2-7,20H,1H3,(H,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50097856
(CHEMBL3589667)Show InChI InChI=1S/C17H11IN2O3/c1-23-8-5-6-9-12(7-8)19-16(17(21)22)13-10-3-2-4-11(18)14(10)20-15(9)13/h2-7,20H,1H3,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 22 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50097854
(CHEMBL3589665)Show InChI InChI=1S/C17H11ClN2O3/c1-23-8-5-6-9-12(7-8)19-16(17(21)22)13-10-3-2-4-11(18)14(10)20-15(9)13/h2-7,20H,1H3,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human)) | BDBM50097855
(CHEMBL3589666)Show InChI InChI=1S/C17H11BrN2O3/c1-23-8-5-6-9-12(7-8)19-16(17(21)22)13-10-3-2-4-11(18)14(10)20-15(9)13/h2-7,20H,1H3,(H,21,22) | PDB MMDB
NCI pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK2 expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50097854
(CHEMBL3589665)Show InChI InChI=1S/C17H11ClN2O3/c1-23-8-5-6-9-12(7-8)19-16(17(21)22)13-10-3-2-4-11(18)14(10)20-15(9)13/h2-7,20H,1H3,(H,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 3
(Homo sapiens (Human)) | BDBM50097863
(CHEMBL3589674)Show SMILES COc1cccc(c1)-c1ccc2nc(C(O)=O)c3c4cccc(Cl)c4[nH]c3c2c1 Show InChI InChI=1S/C23H15ClN2O3/c1-29-14-5-2-4-12(10-14)13-8-9-18-16(11-13)21-19(22(25-18)23(27)28)15-6-3-7-17(24)20(15)26-21/h2-11,26H,1H3,(H,27,28) | PDB
KEGG
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 30 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK3 expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50097867
(CHEMBL3589660)Show InChI InChI=1S/C16H9ClN2O2/c17-10-6-3-5-9-12-14(19-13(9)10)8-4-1-2-7-11(8)18-15(12)16(20)21/h1-7,19H,(H,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50097872
(CHEMBL3589663)Show InChI InChI=1S/C17H12N2O3/c1-22-12-8-4-6-10-13-15(19-14(10)12)9-5-2-3-7-11(9)18-16(13)17(20)21/h2-8,19H,1H3,(H,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50097868
(CHEMBL3589661)Show InChI InChI=1S/C16H9BrN2O2/c17-10-6-3-5-9-12-14(19-13(9)10)8-4-1-2-7-11(8)18-15(12)16(20)21/h1-7,19H,(H,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human)) | BDBM50097854
(CHEMBL3589665)Show InChI InChI=1S/C17H11ClN2O3/c1-23-8-5-6-9-12(7-8)19-16(17(21)22)13-10-3-2-4-11(18)14(10)20-15(9)13/h2-7,20H,1H3,(H,21,22) | PDB MMDB
NCI pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 33 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK2 expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK4
(Mus musculus) | BDBM50097868
(CHEMBL3589661)Show InChI InChI=1S/C16H9BrN2O2/c17-10-6-3-5-9-12-14(19-13(9)10)8-4-1-2-7-11(8)18-15(12)16(20)21/h1-7,19H,(H,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK4 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50097862
(CHEMBL3589673)Show InChI InChI=1S/C17H11ClN2O3/c1-23-8-5-6-12-10(7-8)15-13(16(19-12)17(21)22)9-3-2-4-11(18)14(9)20-15/h2-7,20H,1H3,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 39 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human)) | BDBM50097867
(CHEMBL3589660)Show InChI InChI=1S/C16H9ClN2O2/c17-10-6-3-5-9-12-14(19-13(9)10)8-4-1-2-7-11(8)18-15(12)16(20)21/h1-7,19H,(H,20,21) | PDB MMDB
NCI pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 40 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK2 expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50097863
(CHEMBL3589674)Show SMILES COc1cccc(c1)-c1ccc2nc(C(O)=O)c3c4cccc(Cl)c4[nH]c3c2c1 Show InChI InChI=1S/C23H15ClN2O3/c1-29-14-5-2-4-12(10-14)13-8-9-18-16(11-13)21-19(22(25-18)23(27)28)15-6-3-7-17(24)20(15)26-21/h2-11,26H,1H3,(H,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 41 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK4
(Mus musculus) | BDBM50097855
(CHEMBL3589666)Show InChI InChI=1S/C17H11BrN2O3/c1-23-8-5-6-9-12(7-8)19-16(17(21)22)13-10-3-2-4-11(18)14(10)20-15(9)13/h2-7,20H,1H3,(H,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 42 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK4 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK4
(Mus musculus) | BDBM50097867
(CHEMBL3589660)Show InChI InChI=1S/C16H9ClN2O2/c17-10-6-3-5-9-12-14(19-13(9)10)8-4-1-2-7-11(8)18-15(12)16(20)21/h1-7,19H,(H,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK4 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50097865
(CHEMBL3589774)Show InChI InChI=1S/C14H7ClN2O2S/c15-7-3-1-2-6-9-11(17-10(6)7)13-8(4-5-20-13)16-12(9)14(18)19/h1-5,17H,(H,18,19) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 53 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Mus musculus) | BDBM50097868
(CHEMBL3589661)Show InChI InChI=1S/C16H9BrN2O2/c17-10-6-3-5-9-12-14(19-13(9)10)8-4-1-2-7-11(8)18-15(12)16(20)21/h1-7,19H,(H,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK2 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50097864
(CHEMBL3589675)Show SMILES COc1ccc(cc1)-c1ccc2nc(C(O)=O)c3c4cccc(Cl)c4[nH]c3c2c1 Show InChI InChI=1S/C23H15ClN2O3/c1-29-14-8-5-12(6-9-14)13-7-10-18-16(11-13)21-19(22(25-18)23(27)28)15-3-2-4-17(24)20(15)26-21/h2-11,26H,1H3,(H,27,28) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 56 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Mus musculus) | BDBM50097867
(CHEMBL3589660)Show InChI InChI=1S/C16H9ClN2O2/c17-10-6-3-5-9-12-14(19-13(9)10)8-4-1-2-7-11(8)18-15(12)16(20)21/h1-7,19H,(H,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 61 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK2 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK4
(Mus musculus) | BDBM50097854
(CHEMBL3589665)Show InChI InChI=1S/C17H11ClN2O3/c1-23-8-5-6-9-12(7-8)19-16(17(21)22)13-10-3-2-4-11(18)14(10)20-15(9)13/h2-7,20H,1H3,(H,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 68 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK4 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human)) | BDBM50097863
(CHEMBL3589674)Show SMILES COc1cccc(c1)-c1ccc2nc(C(O)=O)c3c4cccc(Cl)c4[nH]c3c2c1 Show InChI InChI=1S/C23H15ClN2O3/c1-29-14-5-2-4-12(10-14)13-8-9-18-16(11-13)21-19(22(25-18)23(27)28)15-6-3-7-17(24)20(15)26-21/h2-11,26H,1H3,(H,27,28) | PDB MMDB
NCI pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 79 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK2 expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50097868
(CHEMBL3589661)Show InChI InChI=1S/C16H9BrN2O2/c17-10-6-3-5-9-12-14(19-13(9)10)8-4-1-2-7-11(8)18-15(12)16(20)21/h1-7,19H,(H,20,21) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 80 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1B expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50097862
(CHEMBL3589673)Show InChI InChI=1S/C17H11ClN2O3/c1-23-8-5-6-12-10(7-8)15-13(16(19-12)17(21)22)9-3-2-4-11(18)14(9)20-15/h2-7,20H,1H3,(H,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Mus musculus) | BDBM50097855
(CHEMBL3589666)Show InChI InChI=1S/C17H11BrN2O3/c1-23-8-5-6-9-12(7-8)19-16(17(21)22)13-10-3-2-4-11(18)14(10)20-15(9)13/h2-7,20H,1H3,(H,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK2 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM50097872
(CHEMBL3589663)Show InChI InChI=1S/C17H12N2O3/c1-22-12-8-4-6-10-13-15(19-14(10)12)9-5-2-3-7-11(9)18-16(13)17(20)21/h2-8,19H,1H3,(H,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK9 expressed in insect cells using CDK7/9 tide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50097861
(CHEMBL3589672)Show InChI InChI=1S/C16H8BrIN2O2/c17-10-3-1-2-8-12-14(20-13(8)10)9-6-7(18)4-5-11(9)19-15(12)16(21)22/h1-6,20H,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 120 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50097867
(CHEMBL3589660)Show InChI InChI=1S/C16H9ClN2O2/c17-10-6-3-5-9-12-14(19-13(9)10)8-4-1-2-7-11(8)18-15(12)16(20)21/h1-7,19H,(H,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human)) | BDBM50097861
(CHEMBL3589672)Show InChI InChI=1S/C16H8BrIN2O2/c17-10-3-1-2-8-12-14(20-13(8)10)9-6-7(18)4-5-11(9)19-15(12)16(21)22/h1-6,20H,(H,21,22) | PDB MMDB
NCI pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK2 expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50097866
(CHEMBL3589775)Show InChI InChI=1S/C15H8BrN3O2/c16-8-4-1-3-7-10-13(19-11(7)8)12-9(5-2-6-17-12)18-14(10)15(20)21/h1-6,19H,(H,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 130 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM50097868
(CHEMBL3589661)Show InChI InChI=1S/C16H9BrN2O2/c17-10-6-3-5-9-12-14(19-13(9)10)8-4-1-2-7-11(8)18-15(12)16(20)21/h1-7,19H,(H,20,21) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 160 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK9 expressed in insect cells using CDK7/9 tide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50097865
(CHEMBL3589774)Show InChI InChI=1S/C14H7ClN2O2S/c15-7-3-1-2-6-9-11(17-10(6)7)13-8(4-5-20-13)16-12(9)14(18)19/h1-5,17H,(H,18,19) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 170 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK2
(Mus musculus) | BDBM50097870
(CHEMBL3589664)Show InChI InChI=1S/C17H11FN2O3/c1-23-8-5-6-9-12(7-8)19-16(17(21)22)13-10-3-2-4-11(18)14(10)20-15(9)13/h2-7,20H,1H3,(H,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK2 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50097860
(CHEMBL3589671)Show InChI InChI=1S/C16H8ClIN2O2/c17-10-3-1-2-8-12-14(20-13(8)10)9-6-7(18)4-5-11(9)19-15(12)16(21)22/h1-6,20H,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | 180 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Dual specificity protein kinase CLK4
(Mus musculus) | BDBM50097870
(CHEMBL3589664)Show InChI InChI=1S/C17H11FN2O3/c1-23-8-5-6-9-12(7-8)19-16(17(21)22)13-10-3-2-4-11(18)14(10)20-15(9)13/h2-7,20H,1H3,(H,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK4 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50097867
(CHEMBL3589660)Show InChI InChI=1S/C16H9ClN2O2/c17-10-6-3-5-9-12-14(19-13(9)10)8-4-1-2-7-11(8)18-15(12)16(20)21/h1-7,19H,(H,20,21) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1B expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK4
(Mus musculus) | BDBM50097869
(CHEMBL3589662)Show InChI InChI=1S/C16H9IN2O2/c17-10-6-3-5-9-12-14(19-13(9)10)8-4-1-2-7-11(8)18-15(12)16(20)21/h1-7,19H,(H,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Similars
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK4 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Cyclin-dependent kinase 9
(Homo sapiens (Human)) | BDBM50097862
(CHEMBL3589673)Show InChI InChI=1S/C17H11ClN2O3/c1-23-8-5-6-12-10(7-8)15-13(16(19-12)17(21)22)9-3-2-4-11(18)14(9)20-15/h2-7,20H,1H3,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 210 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant CDK9 expressed in insect cells using CDK7/9 tide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 2
(Homo sapiens (Human)) | BDBM50097860
(CHEMBL3589671)Show InChI InChI=1S/C16H8ClIN2O2/c17-10-3-1-2-8-12-14(20-13(8)10)9-6-7(18)4-5-11(9)19-15(12)16(21)22/h1-6,20H,(H,21,22) | PDB MMDB
NCI pathway KEGG
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK2 expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50097863
(CHEMBL3589674)Show SMILES COc1cccc(c1)-c1ccc2nc(C(O)=O)c3c4cccc(Cl)c4[nH]c3c2c1 Show InChI InChI=1S/C23H15ClN2O3/c1-29-14-5-2-4-12(10-14)13-8-9-18-16(11-13)21-19(22(25-18)23(27)28)15-6-3-7-17(24)20(15)26-21/h2-11,26H,1H3,(H,27,28) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 220 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
(Homo sapiens (Human)) | BDBM50097855
(CHEMBL3589666)Show InChI InChI=1S/C17H11BrN2O3/c1-23-8-5-6-9-12(7-8)19-16(17(21)22)13-10-3-2-4-11(18)14(10)20-15(9)13/h2-7,20H,1H3,(H,21,22) | PDB
UniProtKB/SwissProt
antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 230 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1B expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50097858
(CHEMBL3589669)Show SMILES CCOc1ccc2c3[nH]c4c(Cl)cccc4c3c(nc2c1)C(O)=O Show InChI InChI=1S/C18H13ClN2O3/c1-2-24-9-6-7-10-13(8-9)20-17(18(22)23)14-11-4-3-5-12(19)15(11)21-16(10)14/h3-8,21H,2H2,1H3,(H,22,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 240 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50097866
(CHEMBL3589775)Show InChI InChI=1S/C15H8BrN3O2/c16-8-4-1-3-7-10-13(19-11(7)8)12-9(5-2-6-17-12)18-14(10)15(20)21/h1-6,19H,(H,20,21) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 280 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50097864
(CHEMBL3589675)Show SMILES COc1ccc(cc1)-c1ccc2nc(C(O)=O)c3c4cccc(Cl)c4[nH]c3c2c1 Show InChI InChI=1S/C23H15ClN2O3/c1-29-14-8-5-12(6-9-14)13-7-10-18-16(11-13)21-19(22(25-18)23(27)28)15-3-2-4-17(24)20(15)26-21/h2-11,26H,1H3,(H,27,28) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity tyrosine-phosphorylation-regulated kinase 1A
(Homo sapiens (Human)) | BDBM50097870
(CHEMBL3589664)Show InChI InChI=1S/C17H11FN2O3/c1-23-8-5-6-9-12(7-8)19-16(17(21)22)13-10-3-2-4-11(18)14(10)20-15(9)13/h2-7,20H,1H3,(H,21,22) | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 320 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of human recombinant DYRK1A expressed in Escherichia coli using RS peptide as substrate |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |
Dual specificity protein kinase CLK1
(Mus musculus) | BDBM50097870
(CHEMBL3589664)Show InChI InChI=1S/C17H11FN2O3/c1-23-8-5-6-9-12(7-8)19-16(17(21)22)13-10-3-2-4-11(18)14(10)20-15(9)13/h2-7,20H,1H3,(H,21,22) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
Technische Universit£t Braunschweig
Curated by ChEMBL
| Assay Description Inhibition of mouse recombinant CLK1 expressed in Escherichia coli using RS peptide as substrate after 30 mins by scintillation counting analysis |
J Med Chem 58: 3131-43 (2015)
Article DOI: 10.1021/jm501994d BindingDB Entry DOI: 10.7270/Q2736SPK |
More data for this Ligand-Target Pair | |