Compile Data Set for Download or QSAR

Found 39 hits Enz. Inhib. hit(s) with all data for entry = 50046292   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103899 (CHEMBL3594105) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4[nH]c(=O)n(c4C)-c4ccccc4Cl)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 |(3.99,-2.77,;3.99,-1.54,;2.66,-.77,;1.33,-1.54,;,-.77,;-1.33,-1.54,;-1.33,-3.08,;-2.66,-3.85,;-3.99,-3.09,;-5.32,-3.86,;-5.32,-5.4,;-6.65,-6.18,;-6.64,-7.72,;-5.58,-8.33,;-7.98,-8.49,;-9.36,-7.86,;-10.39,-9.01,;-11.62,-8.88,;-9.62,-10.34,;-8.11,-10.02,;-7.19,-10.83,;-10.24,-11.75,;-9.24,-12.92,;-9.75,-14.37,;-11.27,-14.65,;-12.27,-13.48,;-11.75,-12.03,;-12.55,-11.09,;-3.98,-6.17,;-2.65,-5.39,;-1.58,-6.01,;-2.68,-.77,;-2.68,.77,;-1.33,1.54,;,.77,;1.33,1.54,;2.66,.77,;3.99,1.54,;3.99,3.08,;5.33,3.86,;5.32,5.4,;6.66,6.17,;6.66,7.71,;7.99,8.48,;9.32,7.71,;10.39,8.33,;9.32,6.17,;7.99,5.4,)| Show InChI InChI=1S/C35H36ClFN6O5/c1-22-33(40-35(45)43(22)28-8-5-4-7-25(28)36)34(44)39-23-9-10-30(26(37)19-23)48-29-11-12-38-27-21-32(31(46-3)20-24(27)29)47-18-6-13-42-16-14-41(2)15-17-42/h4-5,7-12,19-21H,6,13-18H2,1-3H3,(H,39,44)(H,40,45)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103900 (CHEMBL3594104) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccccc5Cl)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 |(3.99,-2.77,;3.99,-1.54,;2.66,-.77,;1.33,-1.54,;,-.77,;-1.33,-1.54,;-1.33,-3.08,;-2.66,-3.85,;-3.99,-3.09,;-5.32,-3.86,;-5.32,-5.4,;-6.65,-6.18,;-6.64,-7.72,;-5.58,-8.33,;-7.98,-8.49,;-9.36,-7.86,;-9.62,-6.65,;-10.39,-9.01,;-11.93,-8.85,;-12.44,-7.4,;-13.96,-7.13,;-14.95,-8.3,;-14.43,-9.75,;-12.91,-10.02,;-12.5,-11.18,;-9.62,-10.34,;-10.12,-11.47,;-8.11,-10.02,;-7.19,-10.83,;-3.98,-6.17,;-2.65,-5.39,;-1.58,-6.01,;-2.68,-.77,;-2.68,.77,;-1.33,1.54,;,.77,;1.33,1.54,;2.66,.77,;3.99,1.54,;3.99,3.08,;5.33,3.86,;5.32,5.4,;6.66,6.17,;6.66,7.71,;7.99,8.48,;9.32,7.71,;10.39,8.33,;9.32,6.17,;7.99,5.4,)| Show InChI InChI=1S/C36H38ClFN6O5/c1-23-34(42(3)36(46)44(23)29-9-6-5-8-26(29)37)35(45)40-24-10-11-31(27(38)20-24)49-30-12-13-39-28-22-33(32(47-4)21-25(28)30)48-19-7-14-43-17-15-41(2)16-18-43/h5-6,8-13,20-22H,7,14-19H2,1-4H3,(H,40,45)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Macrophage-stimulating protein receptor (Homo sapiens (Human))	BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of Ron (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103901 (CHEMBL3594103) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccccc5Cl)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 |(3.99,-2.77,;3.99,-1.54,;2.66,-.77,;1.33,-1.54,;,-.77,;-1.33,-1.54,;-1.33,-3.08,;-2.66,-3.85,;-3.99,-3.09,;-5.32,-3.86,;-5.32,-5.4,;-6.65,-6.18,;-6.64,-7.72,;-5.58,-8.33,;-7.98,-8.49,;-9.36,-7.86,;-9.62,-6.65,;-10.39,-9.01,;-11.93,-8.85,;-12.44,-7.4,;-13.96,-7.13,;-14.95,-8.3,;-14.43,-9.75,;-12.91,-10.02,;-12.5,-11.18,;-9.62,-10.34,;-10.12,-11.47,;-8.11,-10.02,;-7.19,-10.83,;-3.98,-6.17,;-2.65,-5.39,;-1.58,-6.01,;-2.68,-.77,;-2.68,.77,;-1.33,1.54,;,.77,;1.33,1.54,;2.66,.77,;3.99,1.54,;3.99,3.08,;5.33,3.86,;5.32,5.4,;6.66,6.17,;6.66,7.71,;7.99,8.48,;9.32,7.71,;10.39,8.33,;9.32,6.17,;7.99,5.4,)| Show InChI InChI=1S/C37H39ClFN5O5/c1-23-13-17-43(18-14-23)16-7-19-48-34-22-29-26(21-33(34)47-4)31(12-15-40-29)49-32-11-10-25(20-28(32)39)41-36(45)35-24(2)44(37(46)42(35)3)30-9-6-5-8-27(30)38/h5-6,8-12,15,20-23H,7,13-14,16-19H2,1-4H3,(H,41,45)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103917 (CHEMBL3593692) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(Cl)cc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 Show InChI InChI=1S/C36H38ClFN6O5/c1-23-34(42(3)36(46)44(23)26-9-6-24(37)7-10-26)35(45)40-25-8-11-31(28(38)20-25)49-30-12-13-39-29-22-33(32(47-4)21-27(29)30)48-19-5-14-43-17-15-41(2)16-18-43/h6-13,20-22H,5,14-19H2,1-4H3,(H,40,45)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.40	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103910 (CHEMBL3593888) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(F)c(Cl)c5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 Show InChI InChI=1S/C36H37ClF2N6O5/c1-22-34(43(3)36(47)45(22)24-7-8-27(38)26(37)19-24)35(46)41-23-6-9-31(28(39)18-23)50-30-10-11-40-29-21-33(32(48-4)20-25(29)30)49-17-5-12-44-15-13-42(2)14-16-44/h6-11,18-21H,5,12-17H2,1-4H3,(H,41,46)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103919 (CHEMBL3593690) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(F)cc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 Show InChI InChI=1S/C36H38F2N6O5/c1-23-34(42(3)36(46)44(23)26-9-6-24(37)7-10-26)35(45)40-25-8-11-31(28(38)20-25)49-30-12-13-39-29-22-33(32(47-4)21-27(29)30)48-19-5-14-43-17-15-41(2)16-18-43/h6-13,20-22H,5,14-19H2,1-4H3,(H,40,45)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.40	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of FLT-3 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103918 (CHEMBL3593691) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(Cl)cc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 Show InChI InChI=1S/C37H39ClFN5O5/c1-23-13-17-43(18-14-23)16-5-19-48-34-22-30-28(21-33(34)47-4)31(12-15-40-30)49-32-11-8-26(20-29(32)39)41-36(45)35-24(2)44(37(46)42(35)3)27-9-6-25(38)7-10-27/h6-12,15,20-23H,5,13-14,16-19H2,1-4H3,(H,41,45)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103912 (CHEMBL3593886) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(F)c(F)c5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 Show InChI InChI=1S/C36H37F3N6O5/c1-22-34(43(3)36(47)45(22)24-7-8-26(37)27(38)19-24)35(46)41-23-6-9-31(28(39)18-23)50-30-10-11-40-29-21-33(32(48-4)20-25(29)30)49-17-5-12-44-15-13-42(2)14-16-44/h6-11,18-21H,5,12-17H2,1-4H3,(H,41,46)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103920 (CHEMBL3593689) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(F)cc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 Show InChI InChI=1S/C37H39F2N5O5/c1-23-13-17-43(18-14-23)16-5-19-48-34-22-30-28(21-33(34)47-4)31(12-15-40-30)49-32-11-8-26(20-29(32)39)41-36(45)35-24(2)44(37(46)42(35)3)27-9-6-25(38)7-10-27/h6-12,15,20-23H,5,13-14,16-19H2,1-4H3,(H,41,45)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.30	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Kit (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103911 (CHEMBL3593887) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(F)c(Cl)c5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 Show InChI InChI=1S/C37H38ClF2N5O5/c1-22-11-15-44(16-12-22)14-5-17-49-34-21-30-26(20-33(34)48-4)31(10-13-41-30)50-32-9-6-24(18-29(32)40)42-36(46)35-23(2)45(37(47)43(35)3)25-7-8-28(39)27(38)19-25/h6-10,13,18-22H,5,11-12,14-17H2,1-4H3,(H,42,46)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	6.70	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103913 (CHEMBL3593885) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(F)c(F)c5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 Show InChI InChI=1S/C37H38F3N5O5/c1-22-11-15-44(16-12-22)14-5-17-49-34-21-30-26(20-33(34)48-4)31(10-13-41-30)50-32-9-6-24(18-29(32)40)42-36(46)35-23(2)45(37(47)43(35)3)25-7-8-27(38)28(39)19-25/h6-10,13,18-22H,5,11-12,14-17H2,1-4H3,(H,42,46)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7.40	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103902 (CHEMBL3594102) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccccc5C(F)(F)F)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 |(3.99,-2.77,;3.99,-1.54,;2.66,-.77,;1.33,-1.54,;,-.77,;-1.33,-1.54,;-1.33,-3.08,;-2.66,-3.85,;-3.99,-3.09,;-5.32,-3.86,;-5.32,-5.4,;-6.65,-6.18,;-6.64,-7.72,;-5.58,-8.33,;-7.98,-8.49,;-9.36,-7.86,;-9.62,-6.65,;-10.39,-9.01,;-11.93,-8.85,;-12.44,-7.4,;-13.96,-7.13,;-14.95,-8.3,;-14.43,-9.75,;-12.91,-10.02,;-12.39,-11.47,;-11.18,-11.69,;-13.18,-12.41,;-11.97,-12.63,;-9.62,-10.34,;-10.12,-11.47,;-8.11,-10.02,;-7.19,-10.83,;-3.98,-6.17,;-2.65,-5.39,;-1.58,-6.01,;-2.68,-.77,;-2.68,.77,;-1.33,1.54,;,.77,;1.33,1.54,;2.66,.77,;3.99,1.54,;3.99,3.08,;5.33,3.86,;5.32,5.4,;6.66,6.17,;6.66,7.71,;7.99,8.48,;9.32,7.71,;10.39,8.33,;9.32,6.17,;7.99,5.4,)| Show InChI InChI=1S/C37H38F4N6O5/c1-23-34(45(3)36(49)47(23)29-9-6-5-8-26(29)37(39,40)41)35(48)43-24-10-11-31(27(38)20-24)52-30-12-13-42-28-22-33(32(50-4)21-25(28)30)51-19-7-14-46-17-15-44(2)16-18-46/h5-6,8-13,20-22H,7,14-19H2,1-4H3,(H,43,48)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8.10	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103906 (CHEMBL3593254) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(cc5)C(F)(F)F)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 Show InChI InChI=1S/C37H38F4N6O5/c1-23-34(45(3)36(49)47(23)26-9-6-24(7-10-26)37(39,40)41)35(48)43-25-8-11-31(28(38)20-25)52-30-12-13-42-29-22-33(32(50-4)21-27(29)30)51-19-5-14-46-17-15-44(2)16-18-46/h6-13,20-22H,5,14-19H2,1-4H3,(H,43,48)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103903 (CHEMBL3594101) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccccc5C(F)(F)F)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 |(3.99,-2.77,;3.99,-1.54,;2.66,-.77,;1.33,-1.54,;,-.77,;-1.33,-1.54,;-1.33,-3.08,;-2.66,-3.85,;-3.99,-3.09,;-5.32,-3.86,;-5.32,-5.4,;-6.65,-6.18,;-6.64,-7.72,;-5.58,-8.33,;-7.98,-8.49,;-9.36,-7.86,;-9.62,-6.65,;-10.39,-9.01,;-11.92,-8.85,;-12.44,-7.4,;-13.96,-7.13,;-14.95,-8.3,;-14.43,-9.75,;-12.91,-10.02,;-12.39,-11.47,;-11.18,-11.69,;-13.18,-12.41,;-11.97,-12.63,;-9.62,-10.34,;-10.12,-11.47,;-8.11,-10.02,;-7.19,-10.83,;-3.98,-6.17,;-2.65,-5.39,;-1.58,-6.01,;-2.68,-.77,;-2.68,.77,;-1.33,1.54,;,.77,;1.33,1.54,;2.66,.77,;3.99,1.54,;3.99,3.08,;5.33,3.86,;5.32,5.4,;6.66,6.17,;6.66,7.71,;7.99,8.48,;9.32,7.71,;10.39,8.33,;9.32,6.17,;7.99,5.4,)| Show InChI InChI=1S/C38H39F4N5O5/c1-23-13-17-46(18-14-23)16-7-19-51-34-22-29-26(21-33(34)50-4)31(12-15-43-29)52-32-11-10-25(20-28(32)39)44-36(48)35-24(2)47(37(49)45(35)3)30-9-6-5-8-27(30)38(40,41)42/h5-6,8-12,15,20-23H,7,13-14,16-19H2,1-4H3,(H,44,48)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103915 (CHEMBL3593883) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(Br)cc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 Show InChI InChI=1S/C36H38BrFN6O5/c1-23-34(42(3)36(46)44(23)26-9-6-24(37)7-10-26)35(45)40-25-8-11-31(28(38)20-25)49-30-12-13-39-29-22-33(32(47-4)21-27(29)30)48-19-5-14-43-17-15-41(2)16-18-43/h6-13,20-22H,5,14-19H2,1-4H3,(H,40,45)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103907 (CHEMBL3593891) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(cc5)C(F)(F)F)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 Show InChI InChI=1S/C38H39F4N5O5/c1-23-13-17-46(18-14-23)16-5-19-51-34-22-30-28(21-33(34)50-4)31(12-15-43-30)52-32-11-8-26(20-29(32)39)44-36(48)35-24(2)47(37(49)45(35)3)27-9-6-25(7-10-27)38(40,41)42/h6-12,15,20-23H,5,13-14,16-19H2,1-4H3,(H,44,48)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103916 (CHEMBL3593882) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(Br)cc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 Show InChI InChI=1S/C37H39BrFN5O5/c1-23-13-17-43(18-14-23)16-5-19-48-34-22-30-28(21-33(34)47-4)31(12-15-40-30)49-32-11-8-26(20-29(32)39)41-36(45)35-24(2)44(37(46)42(35)3)27-9-6-25(38)7-10-27/h6-12,15,20-23H,5,13-14,16-19H2,1-4H3,(H,41,45)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103914 (CHEMBL3593884) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(F)c(F)c5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C35H34F3N5O6/c1-21-33(41(2)35(45)43(21)23-6-7-25(36)26(37)18-23)34(44)40-22-5-8-30(27(38)17-22)49-29-9-10-39-28-20-32(31(46-3)19-24(28)29)48-14-4-11-42-12-15-47-16-13-42/h5-10,17-20H,4,11-16H2,1-3H3,(H,40,44)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103904 (CHEMBL3594100) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5cccc(c5)C(F)(F)F)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 Show InChI InChI=1S/C37H38F4N6O5/c1-23-34(45(3)36(49)47(23)26-8-5-7-24(19-26)37(39,40)41)35(48)43-25-9-10-31(28(38)20-25)52-30-11-12-42-29-22-33(32(50-4)21-27(29)30)51-18-6-13-46-16-14-44(2)15-17-46/h5,7-12,19-22H,6,13-18H2,1-4H3,(H,43,48)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103908 (CHEMBL3593890) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(OC(F)(F)F)cc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 Show InChI InChI=1S/C37H38F4N6O6/c1-23-34(45(3)36(49)47(23)25-7-9-26(10-8-25)53-37(39,40)41)35(48)43-24-6-11-31(28(38)20-24)52-30-12-13-42-29-22-33(32(50-4)21-27(29)30)51-19-5-14-46-17-15-44(2)16-18-46/h6-13,20-22H,5,14-19H2,1-4H3,(H,43,48)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103922 (CHEMBL3593686) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(C)cc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 Show InChI InChI=1S/C37H41FN6O5/c1-24-7-10-27(11-8-24)44-25(2)35(42(4)37(44)46)36(45)40-26-9-12-32(29(38)21-26)49-31-13-14-39-30-23-34(33(47-5)22-28(30)31)48-20-6-15-43-18-16-41(3)17-19-43/h7-14,21-23H,6,15-20H2,1-5H3,(H,40,45)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103923 (CHEMBL3593684) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccccc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 Show InChI InChI=1S/C36H39FN6O5/c1-24-34(41(3)36(45)43(24)26-9-6-5-7-10-26)35(44)39-25-11-12-31(28(37)21-25)48-30-13-14-38-29-23-33(32(46-4)22-27(29)30)47-20-8-15-42-18-16-40(2)17-19-42/h5-7,9-14,21-23H,8,15-20H2,1-4H3,(H,39,44)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103909 (CHEMBL3593889) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccc(OC(F)(F)F)cc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 Show InChI InChI=1S/C38H39F4N5O6/c1-23-13-17-46(18-14-23)16-5-19-51-34-22-30-28(21-33(34)50-4)31(12-15-43-30)52-32-11-6-25(20-29(32)39)44-36(48)35-24(2)47(37(49)45(35)3)26-7-9-27(10-8-26)53-38(40,41)42/h6-12,15,20-23H,5,13-14,16-19H2,1-4H3,(H,44,48)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103905 (CHEMBL3594099) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5cccc(c5)C(F)(F)F)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 Show InChI InChI=1S/C38H39F4N5O5/c1-23-12-16-46(17-13-23)15-6-18-51-34-22-30-28(21-33(34)50-4)31(11-14-43-30)52-32-10-9-26(20-29(32)39)44-36(48)35-24(2)47(37(49)45(35)3)27-8-5-7-25(19-27)38(40,41)42/h5,7-11,14,19-23H,6,12-13,15-18H2,1-4H3,(H,44,48)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103921 (CHEMBL3593688) Show SMILES COc1ccc(cc1)-n1c(C)c(C(=O)Nc2ccc(Oc3ccnc4cc(OCCCN5CCN(C)CC5)c(OC)cc34)c(F)c2)n(C)c1=O Show InChI InChI=1S/C37H41FN6O6/c1-24-35(42(3)37(46)44(24)26-8-10-27(47-4)11-9-26)36(45)40-25-7-12-32(29(38)21-25)50-31-13-14-39-30-23-34(33(48-5)22-28(30)31)49-20-6-15-43-18-16-41(2)17-19-43/h7-14,21-23H,6,15-20H2,1-5H3,(H,40,45)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103924 (CHEMBL3593683) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccccc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCC(C)CC1 Show InChI InChI=1S/C37H40FN5O5/c1-24-14-18-42(19-15-24)17-8-20-47-34-23-30-28(22-33(34)46-4)31(13-16-39-30)48-32-12-11-26(21-29(32)38)40-36(44)35-25(2)43(37(45)41(35)3)27-9-6-5-7-10-27/h5-7,9-13,16,21-24H,8,14-15,17-20H2,1-4H3,(H,40,44)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103925 (CHEMBL3593682) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccccc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCCCC1 Show InChI InChI=1S/C36H38FN5O5/c1-24-34(40(2)36(44)42(24)26-11-6-4-7-12-26)35(43)39-25-13-14-31(28(37)21-25)47-30-15-16-38-29-23-33(32(45-3)22-27(29)30)46-20-10-19-41-17-8-5-9-18-41/h4,6-7,11-16,21-23H,5,8-10,17-20H2,1-3H3,(H,39,43)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM50103926 (CHEMBL3593680) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4c(C)n(-c5ccccc5)c(=O)n4C)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C35H36FN5O6/c1-23-33(39(2)35(43)41(23)25-8-5-4-6-9-25)34(42)38-24-10-11-30(27(36)20-24)47-29-12-13-37-28-22-32(31(44-3)21-26(28)29)46-17-7-14-40-15-18-45-19-16-40/h4-6,8-13,20-22H,7,14-19H2,1-3H3,(H,38,42)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Met (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Mast/stem cell growth factor receptor Kit (Homo sapiens (Human))	BDBM50103899 (CHEMBL3594105) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4[nH]c(=O)n(c4C)-c4ccccc4Cl)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 |(3.99,-2.77,;3.99,-1.54,;2.66,-.77,;1.33,-1.54,;,-.77,;-1.33,-1.54,;-1.33,-3.08,;-2.66,-3.85,;-3.99,-3.09,;-5.32,-3.86,;-5.32,-5.4,;-6.65,-6.18,;-6.64,-7.72,;-5.58,-8.33,;-7.98,-8.49,;-9.36,-7.86,;-10.39,-9.01,;-11.62,-8.88,;-9.62,-10.34,;-8.11,-10.02,;-7.19,-10.83,;-10.24,-11.75,;-9.24,-12.92,;-9.75,-14.37,;-11.27,-14.65,;-12.27,-13.48,;-11.75,-12.03,;-12.55,-11.09,;-3.98,-6.17,;-2.65,-5.39,;-1.58,-6.01,;-2.68,-.77,;-2.68,.77,;-1.33,1.54,;,.77,;1.33,1.54,;2.66,.77,;3.99,1.54,;3.99,3.08,;5.33,3.86,;5.32,5.4,;6.66,6.17,;6.66,7.71,;7.99,8.48,;9.32,7.71,;10.39,8.33,;9.32,6.17,;7.99,5.4,)| Show InChI InChI=1S/C35H36ClFN6O5/c1-22-33(40-35(45)43(22)28-8-5-4-7-25(28)36)34(44)39-23-9-10-30(26(37)19-23)48-29-11-12-38-27-21-32(31(46-3)20-24(27)29)47-18-6-13-42-16-14-41(2)15-17-42/h4-5,7-12,19-21H,6,13-18H2,1-3H3,(H,39,44)(H,40,45)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of c-Kit (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50103899 (CHEMBL3594105) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4[nH]c(=O)n(c4C)-c4ccccc4Cl)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 |(3.99,-2.77,;3.99,-1.54,;2.66,-.77,;1.33,-1.54,;,-.77,;-1.33,-1.54,;-1.33,-3.08,;-2.66,-3.85,;-3.99,-3.09,;-5.32,-3.86,;-5.32,-5.4,;-6.65,-6.18,;-6.64,-7.72,;-5.58,-8.33,;-7.98,-8.49,;-9.36,-7.86,;-10.39,-9.01,;-11.62,-8.88,;-9.62,-10.34,;-8.11,-10.02,;-7.19,-10.83,;-10.24,-11.75,;-9.24,-12.92,;-9.75,-14.37,;-11.27,-14.65,;-12.27,-13.48,;-11.75,-12.03,;-12.55,-11.09,;-3.98,-6.17,;-2.65,-5.39,;-1.58,-6.01,;-2.68,-.77,;-2.68,.77,;-1.33,1.54,;,.77,;1.33,1.54,;2.66,.77,;3.99,1.54,;3.99,3.08,;5.33,3.86,;5.32,5.4,;6.66,6.17,;6.66,7.71,;7.99,8.48,;9.32,7.71,;10.39,8.33,;9.32,6.17,;7.99,5.4,)| Show InChI InChI=1S/C35H36ClFN6O5/c1-22-33(40-35(45)43(22)28-8-5-4-7-25(28)36)34(44)39-23-9-10-30(26(37)19-23)48-29-11-12-38-27-21-32(31(46-3)20-24(27)29)47-18-6-13-42-16-14-41(2)15-17-42/h4-5,7-12,19-21H,6,13-18H2,1-3H3,(H,39,44)(H,40,45)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of VEGFR-2 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Receptor-type tyrosine-protein kinase FLT3 (Homo sapiens (Human))	BDBM50103899 (CHEMBL3594105) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4[nH]c(=O)n(c4C)-c4ccccc4Cl)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 |(3.99,-2.77,;3.99,-1.54,;2.66,-.77,;1.33,-1.54,;,-.77,;-1.33,-1.54,;-1.33,-3.08,;-2.66,-3.85,;-3.99,-3.09,;-5.32,-3.86,;-5.32,-5.4,;-6.65,-6.18,;-6.64,-7.72,;-5.58,-8.33,;-7.98,-8.49,;-9.36,-7.86,;-10.39,-9.01,;-11.62,-8.88,;-9.62,-10.34,;-8.11,-10.02,;-7.19,-10.83,;-10.24,-11.75,;-9.24,-12.92,;-9.75,-14.37,;-11.27,-14.65,;-12.27,-13.48,;-11.75,-12.03,;-12.55,-11.09,;-3.98,-6.17,;-2.65,-5.39,;-1.58,-6.01,;-2.68,-.77,;-2.68,.77,;-1.33,1.54,;,.77,;1.33,1.54,;2.66,.77,;3.99,1.54,;3.99,3.08,;5.33,3.86,;5.32,5.4,;6.66,6.17,;6.66,7.71,;7.99,8.48,;9.32,7.71,;10.39,8.33,;9.32,6.17,;7.99,5.4,)| Show InChI InChI=1S/C35H36ClFN6O5/c1-22-33(40-35(45)43(22)28-8-5-4-7-25(28)36)34(44)39-23-9-10-30(26(37)19-23)48-29-11-12-38-27-21-32(31(46-3)20-24(27)29)47-18-6-13-42-16-14-41(2)15-17-42/h4-5,7-12,19-21H,6,13-18H2,1-3H3,(H,39,44)(H,40,45)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	134	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of FLT-3 (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Macrophage-stimulating protein receptor (Homo sapiens (Human))	BDBM50103899 (CHEMBL3594105) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4[nH]c(=O)n(c4C)-c4ccccc4Cl)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 |(3.99,-2.77,;3.99,-1.54,;2.66,-.77,;1.33,-1.54,;,-.77,;-1.33,-1.54,;-1.33,-3.08,;-2.66,-3.85,;-3.99,-3.09,;-5.32,-3.86,;-5.32,-5.4,;-6.65,-6.18,;-6.64,-7.72,;-5.58,-8.33,;-7.98,-8.49,;-9.36,-7.86,;-10.39,-9.01,;-11.62,-8.88,;-9.62,-10.34,;-8.11,-10.02,;-7.19,-10.83,;-10.24,-11.75,;-9.24,-12.92,;-9.75,-14.37,;-11.27,-14.65,;-12.27,-13.48,;-11.75,-12.03,;-12.55,-11.09,;-3.98,-6.17,;-2.65,-5.39,;-1.58,-6.01,;-2.68,-.77,;-2.68,.77,;-1.33,1.54,;,.77,;1.33,1.54,;2.66,.77,;3.99,1.54,;3.99,3.08,;5.33,3.86,;5.32,5.4,;6.66,6.17,;6.66,7.71,;7.99,8.48,;9.32,7.71,;10.39,8.33,;9.32,6.17,;7.99,5.4,)| Show InChI InChI=1S/C35H36ClFN6O5/c1-22-33(40-35(45)43(22)28-8-5-4-7-25(28)36)34(44)39-23-9-10-30(26(37)19-23)48-29-11-12-38-27-21-32(31(46-3)20-24(27)29)47-18-6-13-42-16-14-41(2)15-17-42/h4-5,7-12,19-21H,6,13-18H2,1-3H3,(H,39,44)(H,40,45)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of Ron (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50399540 (FORETINIB | US10464902, Foretinib | US10882853, Co...) Show SMILES COc1cc2c(Oc3ccc(NC(=O)C4(CC4)C(=O)Nc4ccc(F)cc4)cc3F)ccnc2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C34H34F2N4O6/c1-43-30-20-25-27(21-31(30)45-16-2-13-40-14-17-44-18-15-40)37-12-9-28(25)46-29-8-7-24(19-26(29)36)39-33(42)34(10-11-34)32(41)38-23-5-3-22(35)4-6-23/h3-9,12,19-21H,2,10-11,13-18H2,1H3,(H,38,41)(H,39,42)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	2.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50103899 (CHEMBL3594105) Show SMILES COc1cc2c(Oc3ccc(NC(=O)c4[nH]c(=O)n(c4C)-c4ccccc4Cl)cc3F)ccnc2cc1OCCCN1CCN(C)CC1 |(3.99,-2.77,;3.99,-1.54,;2.66,-.77,;1.33,-1.54,;,-.77,;-1.33,-1.54,;-1.33,-3.08,;-2.66,-3.85,;-3.99,-3.09,;-5.32,-3.86,;-5.32,-5.4,;-6.65,-6.18,;-6.64,-7.72,;-5.58,-8.33,;-7.98,-8.49,;-9.36,-7.86,;-10.39,-9.01,;-11.62,-8.88,;-9.62,-10.34,;-8.11,-10.02,;-7.19,-10.83,;-10.24,-11.75,;-9.24,-12.92,;-9.75,-14.37,;-11.27,-14.65,;-12.27,-13.48,;-11.75,-12.03,;-12.55,-11.09,;-3.98,-6.17,;-2.65,-5.39,;-1.58,-6.01,;-2.68,-.77,;-2.68,.77,;-1.33,1.54,;,.77,;1.33,1.54,;2.66,.77,;3.99,1.54,;3.99,3.08,;5.33,3.86,;5.32,5.4,;6.66,6.17,;6.66,7.71,;7.99,8.48,;9.32,7.71,;10.39,8.33,;9.32,6.17,;7.99,5.4,)| Show InChI InChI=1S/C35H36ClFN6O5/c1-22-33(40-35(45)43(22)28-8-5-4-7-25(28)36)34(44)39-23-9-10-30(26(37)19-23)48-29-11-12-38-27-21-32(31(46-3)20-24(27)29)47-18-6-13-42-16-14-41(2)15-17-42/h4-5,7-12,19-21H,6,13-18H2,1-3H3,(H,39,44)(H,40,45)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University) Curated by ChEMBL					Assay Description Inhibition of EGFR (unknown origin) using poly (Glu, Tyr) 4:1 as substrate after 30 mins by HTRF assay				Bioorg Med Chem 23: 4410-22 (2015) Article DOI: 10.1016/j.bmc.2015.06.026 BindingDB Entry DOI: 10.7270/Q28G8NG3
					More data for this Ligand-Target Pair