Found 41 hits Enz. Inhib. hit(s) with all data for entry = 50020694 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50220842
(3-butyl-1H-pyrazole-5-carboxylic acid | 5-butyl-1H...)Show InChI InChI=1S/C8H12N2O2/c1-2-3-4-6-5-7(8(11)12)10-9-6/h5H,2-4H2,1H3,(H,9,10)(H,11,12) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50211361
(3-methyl-5-carboxyl-isoxazole | 3-methylisoxazole-...)Show InChI InChI=1S/C5H5NO3/c1-3-2-4(5(7)8)9-6-3/h2H,1H3,(H,7,8) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216521
(5-fluoronicotinic acid | CHEMBL397783)Show InChI InChI=1S/C6H4FNO2/c7-5-1-4(6(9)10)2-8-3-5/h1-3H,(H,9,10) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | n/a | 5.30E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216522
(1-methyl-1H-pyrazole-4-carboxylic acid | CHEMBL393...)Show InChI InChI=1S/C5H6N2O2/c1-7-3-4(2-6-7)5(8)9/h2-3H,1H3,(H,8,9) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216523
(6-propyl-4,6-dihydro-2H-furo[3,4-c]pyrazole-3-carb...)Show InChI InChI=1S/C9H12N2O3/c1-2-3-6-7-5(4-14-6)8(9(12)13)11-10-7/h6H,2-4H2,1H3,(H,10,11)(H,12,13) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.10E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216524
(3-cyclobutyl-1H-pyrazole-5-carboxylic acid | 5-cyc...)Show InChI InChI=1S/C8H10N2O2/c11-8(12)7-4-6(9-10-7)5-2-1-3-5/h4-5H,1-3H2,(H,9,10)(H,11,12) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.62E+4 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216525
(6-Methyl-1,4,5,6-tetrahydrocyclopenta[c]pyrazole-3...)Show InChI InChI=1S/C8H10N2O2/c1-4-2-3-5-6(4)9-10-7(5)8(11)12/h4H,2-3H2,1H3,(H,9,10)(H,11,12) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216527
(5,6-dihydro-2H-thieno[3,2-c]pyrazole-3-carboxylic ...)Show InChI InChI=1S/C6H6N2O2S/c9-6(10)4-5-3(7-8-4)1-2-11-5/h1-2H2,(H,7,8)(H,9,10) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 2.20E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216526
(3-(methoxymethyl)-1H-pyrazole-5-carboxylic acid | ...)Show InChI InChI=1S/C6H8N2O3/c1-11-3-4-2-5(6(9)10)8-7-4/h2H,3H2,1H3,(H,7,8)(H,9,10) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216528
(6-phenyl-2,4,5,6-tetrahydrocyclopenta[c]pyrazole-3...)Show InChI InChI=1S/C13H12N2O2/c16-13(17)12-10-7-6-9(11(10)14-15-12)8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,14,15)(H,16,17) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.20E+4 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216529
(6-methyl-4,6-dihydro-2H-furo[3,4-c]pyrazole-3-carb...)Show InChI InChI=1S/C7H8N2O3/c1-3-5-4(2-12-3)6(7(10)11)9-8-5/h3H,2H2,1H3,(H,8,9)(H,10,11) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216530
(4,6-dihydro-2H-thieno[3,4-c]pyrazole-3-carboxylic ...)Show InChI InChI=1S/C6H6N2O2S/c9-6(10)5-3-1-11-2-4(3)7-8-5/h1-2H2,(H,7,8)(H,9,10) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216531
(5-bromonicotinic acid | CHEMBL247336)Show InChI InChI=1S/C6H4BrNO2/c7-5-1-4(6(9)10)2-8-3-5/h1-3H,(H,9,10) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | n/a | 1.36E+4 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216532
(CHEMBL393226 | isothiazole-4-carboxylic acid)Show InChI InChI=1S/C4H3NO2S/c6-4(7)3-1-5-8-2-3/h1-2H,(H,6,7) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | n/a | 1.50E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50132135
(4,6-Dihydro-1H-furo[3,4-c]pyrazole-3-carboxylic ac...)Show InChI InChI=1S/C6H6N2O3/c9-6(10)5-3-1-11-2-4(3)7-8-5/h1-2H2,(H,7,8)(H,9,10) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216533
(3-cyclopropyl-1H-pyrazole-5-carboxylic acid | 5-cy...)Show InChI InChI=1S/C7H8N2O2/c10-7(11)6-3-5(8-9-6)4-1-2-4/h3-4H,1-2H2,(H,8,9)(H,10,11) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
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CHEMBL MCE PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216535
(3-(hydroxymethyl)-1H-pyrazole-5-carboxylic acid | ...)Show InChI InChI=1S/C5H6N2O3/c8-2-3-1-4(5(9)10)7-6-3/h1,8H,2H2,(H,6,7)(H,9,10) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.50E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216534
(5-methylnicotinic acid | CHEMBL247132)Show InChI InChI=1S/C7H7NO2/c1-5-2-6(7(9)10)4-8-3-5/h2-4H,1H3,(H,9,10) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.60E+4 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216536
(6-propyl-2,4,5,6-tetrahydrocyclopenta[c]pyrazole-3...)Show InChI InChI=1S/C10H14N2O2/c1-2-3-6-4-5-7-8(6)11-12-9(7)10(13)14/h6H,2-5H2,1H3,(H,11,12)(H,13,14) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 6.60E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216537
(3-benzyl-1H-pyrazole-5-carboxylic acid | 5-Benzyl-...)Show InChI InChI=1S/C11H10N2O2/c14-11(15)10-7-9(12-13-10)6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H,12,13)(H,14,15) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 8.90E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216540
(3-(methylsulfinylmethyl)-1H-pyrazole-5-carboxylic ...)Show InChI InChI=1S/C6H8N2O3S/c1-12(11)3-4-2-5(6(9)10)8-7-4/h2H,3H2,1H3,(H,7,8)(H,9,10) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 4.90E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216539
(3-ethyl-1H-pyrazole-5-carboxylic acid | 5-ethyl-1H...)Show InChI InChI=1S/C6H8N2O2/c1-2-4-3-5(6(9)10)8-7-4/h3H,2H2,1H3,(H,7,8)(H,9,10) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 800 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216538
(3-hexyl-1H-pyrazole-5-carboxylic acid | CHEMBL2479...)Show InChI InChI=1S/C10H16N2O2/c1-2-3-4-5-6-8-7-9(10(13)14)12-11-8/h7H,2-6H2,1H3,(H,11,12)(H,13,14) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 5.60E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216541
(CHEMBL613 | POA | PYRAZINOIC ACID | PZA | Rifater ...)Show InChI InChI=1S/C5H4N2O2/c8-5(9)4-3-6-1-2-7-4/h1-3H,(H,8,9) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE MMDB PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | n/a | 6.30E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50211363
(3-isopropyl-1H-pyrazole-5-carboxylic acid | 5-Isop...)Show InChI InChI=1S/C7H10N2O2/c1-4(2)5-3-6(7(10)11)9-8-5/h3-4H,1-2H3,(H,8,9)(H,10,11) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 8.30E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216546
(5-chloronicotinic acid | CHEMBL395178)Show InChI InChI=1S/C6H4ClNO2/c7-5-1-4(6(9)10)2-8-3-5/h1-3H,(H,9,10) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | n/a | 7.60E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50220850
(3-propyl-1H-pyrazole-5-carboxylic acid | 5-propyl-...)Show InChI InChI=1S/C7H10N2O2/c1-2-3-5-4-6(7(10)11)9-8-5/h4H,2-3H2,1H3,(H,8,9)(H,10,11) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216544
(3-(2-methoxyethyl)-1H-pyrazole-5-carboxylic acid |...)Show InChI InChI=1S/C7H10N2O3/c1-12-3-2-5-4-6(7(10)11)9-8-5/h4H,2-3H2,1H3,(H,8,9)(H,10,11) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.22E+4 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216543
(3-formyl-1H-pyrazole-5-carboxylic acid | CHEMBL246...)Show InChI InChI=1S/C5H4N2O3/c8-2-3-1-4(5(9)10)7-6-3/h1-2H,(H,6,7)(H,9,10) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 6.10E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50211364
(3-(3-fluorobenzyl)-1H-pyrazole-5-carboxylic acid |...)Show InChI InChI=1S/C11H9FN2O2/c12-8-3-1-2-7(4-8)5-9-6-10(11(15)16)14-13-9/h1-4,6H,5H2,(H,13,14)(H,15,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50211365
(3-(3-bromobenzyl)-1H-pyrazole-5-carboxylic acid | ...)Show InChI InChI=1S/C11H9BrN2O2/c12-8-3-1-2-7(4-8)5-9-6-10(11(15)16)14-13-9/h1-4,6H,5H2,(H,13,14)(H,15,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.05E+4 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216552
(2-methylthiazole-5-carboxylic acid | CHEMBL247134)Show InChI InChI=1S/C5H5NO2S/c1-3-6-2-4(9-3)5(7)8/h2H,1H3,(H,7,8) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | n/a | 500 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216548
(6-ethyl-4,6-dihydro-2H-furo[3,4-c]pyrazole-3-carbo...)Show InChI InChI=1S/C8H10N2O3/c1-2-5-6-4(3-13-5)7(8(11)12)10-9-6/h5H,2-3H2,1H3,(H,9,10)(H,11,12) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216550
(3-(3-chlorobenzyl)-1H-pyrazole-5-carboxylic acid |...)Show InChI InChI=1S/C11H9ClN2O2/c12-8-3-1-2-7(4-8)5-9-6-10(11(15)16)14-13-9/h1-4,6H,5H2,(H,13,14)(H,15,16) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216551
(3-pentyl-1H-pyrazole-5-carboxylic acid | 5-butylpy...)Show InChI InChI=1S/C9H14N2O2/c1-2-3-4-5-7-6-8(9(12)13)11-10-7/h6H,2-5H2,1H3,(H,10,11)(H,12,13) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM23515
(CHEMBL573 | Niacin | Nicotinic Acid | [5, 6-3H]-ni...)Show InChI InChI=1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem
Patents
Similars
| DrugBank PDB Article PubMed
| n/a | n/a | n/a | n/a | 120 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50211362
(5-methyl-1H-pyrazole-3-carboxylic acid | 5-methyl-...)Show InChI InChI=1S/C5H6N2O2/c1-3-2-4(5(8)9)7-6-3/h2H,1H3,(H,6,7)(H,8,9) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 460 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50132140
(1,4,5,6-Tetrahydro-cyclopentapyrazole-3-carboxylic...)Show InChI InChI=1S/C7H8N2O2/c10-7(11)6-4-2-1-3-5(4)8-9-6/h1-3H2,(H,8,9)(H,10,11) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 860 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216542
(CHEMBL394068 | pyridazine-4-carboxylic acid)Show InChI InChI=1S/C5H4N2O2/c8-5(9)4-1-2-6-7-3-4/h1-3H,(H,8,9) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216547
(3-(methylthiomethyl)-1H-pyrazole-5-carboxylic acid...)Show InChI InChI=1S/C6H8N2O2S/c1-11-3-4-2-5(6(9)10)8-7-4/h2H,3H2,1H3,(H,7,8)(H,9,10) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.70E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |
Hydroxycarboxylic acid receptor 2
(Homo sapiens (Human)) | BDBM50216520
(CHEMBL247316 | pyrimidine-5-carboxylic acid)Show InChI InChI=1S/C5H4N2O2/c8-5(9)4-1-6-3-7-2-4/h1-3H,(H,8,9) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid UniChem
Patents
| Article PubMed
| n/a | n/a | n/a | n/a | 2.90E+3 | n/a | n/a | n/a | n/a |
Arena Pharmaceuticals
Curated by ChEMBL
| Assay Description Agonist activity at human cloned GPR109a receptor by forskolin-stimulated cAMP production test |
Bioorg Med Chem Lett 17: 4914-9 (2007)
Article DOI: 10.1016/j.bmcl.2007.06.028 BindingDB Entry DOI: 10.7270/Q2NP244M |
More data for this Ligand-Target Pair | |