Compile Data Set for Download or QSAR

Found 41 hits Enz. Inhib. hit(s) with all data for entry = 50020920   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50152456 ((S)-3-{3-[4-(3-Acetylamino-phenyl)-piperidin-1-yl]...) Show SMILES COCC1=C([C@@H](N(C(=O)NCCCN2CCC(CC2)c2cccc(NC(C)=O)c2)C(=O)N1)c1ccc(F)c(F)c1)C(=O)OC |t:3| Show InChI InChI=1S/C31H37F2N5O6/c1-19(39)35-23-7-4-6-21(16-23)20-10-14-37(15-11-20)13-5-12-34-30(41)38-28(22-8-9-24(32)25(33)17-22)27(29(40)44-3)26(18-43-2)36-31(38)42/h4,6-9,16-17,20,28H,5,10-15,18H2,1-3H3,(H,34,41)(H,35,39)(H,36,42)/t28-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219036 (CHEMBL388440 | N-{3-[1-(3-{[hydroxy(diphenyl)acety...) Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C(O)(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C33H41N3O3/c1-24(2)31(37)35-29-16-15-25(3)30(23-29)26-17-21-36(22-18-26)20-10-19-34-32(38)33(39,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-16,23-24,26,39H,10,17-22H2,1-3H3,(H,34,38)(H,35,37)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219040 (CHEMBL429464 | N-{3-[1-(3-{[bis(4-fluorophenyl)ace...) Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C33H39F2N3O2/c1-22(2)32(39)37-29-14-5-23(3)30(21-29)24-15-19-38(20-16-24)18-4-17-36-33(40)31(25-6-10-27(34)11-7-25)26-8-12-28(35)13-9-26/h5-14,21-22,24,31H,4,15-20H2,1-3H3,(H,36,40)(H,37,39)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.620	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219026 (CHEMBL243338 | N-{3-[1-(3-{[bis(4-fluorophenyl)ace...) Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCNC(=O)C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C32H37F2N3O2/c1-22(2)31(38)36-29-6-3-5-26(21-29)23-15-19-37(20-16-23)18-4-17-35-32(39)30(24-7-11-27(33)12-8-24)25-9-13-28(34)14-10-25/h3,5-14,21-23,30H,4,15-20H2,1-2H3,(H,35,39)(H,36,38)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219035 (CHEMBL243355 | N-{5-[1-(3-{[bis(4-fluorophenyl)ace...) Show SMILES CC(C)C(=O)Nc1cc(C2CCN(CCCNC(=O)C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)c(F)cc1F Show InChI InChI=1S/C32H35F4N3O2/c1-20(2)31(40)38-29-18-26(27(35)19-28(29)36)21-12-16-39(17-13-21)15-3-14-37-32(41)30(22-4-8-24(33)9-5-22)23-6-10-25(34)11-7-23/h4-11,18-21,30H,3,12-17H2,1-2H3,(H,37,41)(H,38,40)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219037 (1-(4-fluorophenyl)-N-(3-{4-[5-(isobutyrylamino)-2-...) Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C2(CCCCC2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C32H44FN3O2/c1-23(2)30(37)35-28-13-8-24(3)29(22-28)25-14-20-36(21-15-25)19-7-18-34-31(38)32(16-5-4-6-17-32)26-9-11-27(33)12-10-26/h8-13,22-23,25H,4-7,14-21H2,1-3H3,(H,34,38)(H,35,37)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219023 (CHEMBL243138 | N-{3-[1-(3-diphenylacetylamino-prop...) Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C32H39N3O2/c1-24(2)31(36)34-29-16-9-15-28(23-29)25-17-21-35(22-18-25)20-10-19-33-32(37)30(26-11-5-3-6-12-26)27-13-7-4-8-14-27/h3-9,11-16,23-25,30H,10,17-22H2,1-2H3,(H,33,37)(H,34,36)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219029 (CHEMBL390679 | N-{3-[1-(2-diphenylacetylamino-ethy...) Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCNC(=O)C(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C31H37N3O2/c1-23(2)30(35)33-28-15-9-14-27(22-28)24-16-19-34(20-17-24)21-18-32-31(36)29(25-10-5-3-6-11-25)26-12-7-4-8-13-26/h3-15,22-24,29H,16-21H2,1-2H3,(H,32,36)(H,33,35)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219044 (CHEMBL243128 | N-{3-[1-(3-{[bis(4-chlorophenyl)ace...) Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCNC(=O)C(c2ccc(Cl)cc2)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C32H37Cl2N3O2/c1-22(2)31(38)36-29-6-3-5-26(21-29)23-15-19-37(20-16-23)18-4-17-35-32(39)30(24-7-11-27(33)12-8-24)25-9-13-28(34)14-10-25/h3,5-14,21-23,30H,4,15-20H2,1-2H3,(H,35,39)(H,36,38)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219025 (CHEMBL243578 | N-{3-[1-(3-{[bis(4-fluorophenyl)ace...) Show SMILES CC(C)C(=O)Nc1c(F)cc(F)c(C2CCN(CCCNC(=O)C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)c1F Show InChI InChI=1S/C32H34F5N3O2/c1-19(2)31(41)39-30-26(36)18-25(35)28(29(30)37)22-12-16-40(17-13-22)15-3-14-38-32(42)27(20-4-8-23(33)9-5-20)21-6-10-24(34)11-7-21/h4-11,18-19,22,27H,3,12-17H2,1-2H3,(H,38,42)(H,39,41)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219042 (CHEMBL242689 | N-[3-(1-{3-[(diphenylacetyl)amino]p...) Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C33H41N3O2/c1-24(2)32(37)35-29-16-15-25(3)30(23-29)26-17-21-36(22-18-26)20-10-19-34-33(38)31(27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-16,23-24,26,31H,10,17-22H2,1-3H3,(H,34,38)(H,35,37)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219031 (1-(4-fluorophenyl)-N-(3-{4-[5-(isobutylamino)-2-me...) Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C2(CCCC2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C31H42FN3O2/c1-22(2)29(36)34-27-12-7-23(3)28(21-27)24-13-19-35(20-14-24)18-6-17-33-30(37)31(15-4-5-16-31)25-8-10-26(32)11-9-25/h7-12,21-22,24H,4-6,13-20H2,1-3H3,(H,33,37)(H,34,36)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	3.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219032 (CHEMBL242902 | N-(3-{4-[3-(isobutyrylamino)phenyl]...) Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCNC(=O)C(C)(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C33H41N3O2/c1-25(2)31(37)35-30-17-10-12-27(24-30)26-18-22-36(23-19-26)21-11-20-34-32(38)33(3,28-13-6-4-7-14-28)29-15-8-5-9-16-29/h4-10,12-17,24-26H,11,18-23H2,1-3H3,(H,34,38)(H,35,37)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219038 (CHEMBL243507 | N-(3-{4-[3-(isobutylrylamino)phenyl...) Show SMILES CCCCCC(C(=O)NCCCN1CCC(CC1)c1cccc(NC(=O)C(C)C)c1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C37H49N3O2/c1-4-5-12-23-37(32-16-8-6-9-17-32,33-18-10-7-11-19-33)36(42)38-24-14-25-40-26-21-30(22-27-40)31-15-13-20-34(28-31)39-35(41)29(2)3/h6-11,13,15-20,28-30H,4-5,12,14,21-27H2,1-3H3,(H,38,42)(H,39,41)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219043 ((2S)-2-(4-fluorophenyl)-N-(3-{4-[5-(isobutyrylamin...) Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@@H](C)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C28H38FN3O2/c1-19(2)27(33)31-25-11-6-20(3)26(18-25)23-12-16-32(17-13-23)15-5-14-30-28(34)21(4)22-7-9-24(29)10-8-22/h6-11,18-19,21,23H,5,12-17H2,1-4H3,(H,30,34)(H,31,33)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219041 (CHEMBL242901 | N-{3-[4-(3-isobutyrylamino-phenyl)-...) Show SMILES CCC(C(=O)NCCCN1CCC(CC1)c1cccc(NC(=O)C(C)C)c1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C34H43N3O2/c1-4-34(29-14-7-5-8-15-29,30-16-9-6-10-17-30)33(39)35-21-12-22-37-23-19-27(20-24-37)28-13-11-18-31(25-28)36-32(38)26(2)3/h5-11,13-18,25-27H,4,12,19-24H2,1-3H3,(H,35,39)(H,36,38)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219039 ((2R)-2-(4-fluorophenyl)-N-(3-{4-[5-(isobutyrylamin...) Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@H](C)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C28H38FN3O2/c1-19(2)27(33)31-25-11-6-20(3)26(18-25)23-12-16-32(17-13-23)15-5-14-30-28(34)21(4)22-7-9-24(29)10-8-22/h6-11,18-19,21,23H,5,12-17H2,1-4H3,(H,30,34)(H,31,33)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219034 (CHEMBL243129 | N-{3-[1-(6-diphenylacetylamino-hexy...) Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCCCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C35H45N3O2/c1-27(2)34(39)37-32-19-13-18-31(26-32)28-20-24-38(25-21-28)23-12-4-3-11-22-36-35(40)33(29-14-7-5-8-15-29)30-16-9-6-10-17-30/h5-10,13-19,26-28,33H,3-4,11-12,20-25H2,1-2H3,(H,36,40)(H,37,39)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219024 (2-methyl-N-{4-methyl-3-[1-(3-{[(2R)-2-phenylpropan...) Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@@H](C)c2ccccc2)CC1 Show InChI InChI=1S/C28H39N3O2/c1-20(2)27(32)30-25-12-11-21(3)26(19-25)24-13-17-31(18-14-24)16-8-15-29-28(33)22(4)23-9-6-5-7-10-23/h5-7,9-12,19-20,22,24H,8,13-18H2,1-4H3,(H,29,33)(H,30,32)/t22-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	34	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219028 (2-methyl-N-{4-methyl-3-[1-(3-{[(2S)-2-phenylpropan...) Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@H](C)c2ccccc2)CC1 Show InChI InChI=1S/C28H39N3O2/c1-20(2)27(32)30-25-12-11-21(3)26(19-25)24-13-17-31(18-14-24)16-8-15-29-28(33)22(4)23-9-6-5-7-10-23/h5-7,9-12,19-20,22,24H,8,13-18H2,1-4H3,(H,29,33)(H,30,32)/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219033 (CHEMBL243354 | N-{3-[1-(5-diphenylacetylamino-pent...) Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C34H43N3O2/c1-26(2)33(38)36-31-18-12-17-30(25-31)27-19-23-37(24-20-27)22-11-5-10-21-35-34(39)32(28-13-6-3-7-14-28)29-15-8-4-9-16-29/h3-4,6-9,12-18,25-27,32H,5,10-11,19-24H2,1-2H3,(H,35,39)(H,36,38)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219030 (CHEMBL243139 | N-{3-[1-(5-diphenylacetylamino-pent...) Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C33H41N3O2/c1-25(2)32(37)35-30-17-11-16-29(24-30)26-18-22-36(23-19-26)21-10-9-20-34-33(38)31(27-12-5-3-6-13-27)28-14-7-4-8-15-28/h3-8,11-17,24-26,31H,9-10,18-23H2,1-2H3,(H,34,38)(H,35,37)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219027 (CHEMBL388234 | N-{3-[1-(3-diphenylacetylamino-prop...) Show SMILES CC(C)C(=O)Nc1cc(ccc1C)C1CCN(CCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C33H41N3O2/c1-24(2)32(37)35-30-23-29(16-15-25(30)3)26-17-21-36(22-18-26)20-10-19-34-33(38)31(27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-16,23-24,26,31H,10,17-22H2,1-3H3,(H,34,38)(H,35,37)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Displacement of [3H]SNAP 7941 from rat MCHR1 expressed in HEK293 cells				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219026 (CHEMBL243338 | N-{3-[1-(3-{[bis(4-fluorophenyl)ace...) Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCNC(=O)C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C32H37F2N3O2/c1-22(2)31(38)36-29-6-3-5-26(21-29)23-15-19-37(20-16-23)18-4-17-35-32(39)30(24-7-11-27(33)12-8-24)25-9-13-28(34)14-10-25/h3,5-14,21-23,30H,4,15-20H2,1-2H3,(H,35,39)(H,36,38)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219023 (CHEMBL243138 | N-{3-[1-(3-diphenylacetylamino-prop...) Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C32H39N3O2/c1-24(2)31(36)34-29-16-9-15-28(23-29)25-17-21-35(22-18-25)20-10-19-33-32(37)30(26-11-5-3-6-12-26)27-13-7-4-8-14-27/h3-9,11-16,23-25,30H,10,17-22H2,1-2H3,(H,33,37)(H,34,36)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219043 ((2S)-2-(4-fluorophenyl)-N-(3-{4-[5-(isobutyrylamin...) Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@@H](C)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C28H38FN3O2/c1-19(2)27(33)31-25-11-6-20(3)26(18-25)23-12-16-32(17-13-23)15-5-14-30-28(34)21(4)22-7-9-24(29)10-8-22/h6-11,18-19,21,23H,5,12-17H2,1-4H3,(H,30,34)(H,31,33)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219040 (CHEMBL429464 | N-{3-[1-(3-{[bis(4-fluorophenyl)ace...) Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C(c2ccc(F)cc2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C33H39F2N3O2/c1-22(2)32(39)37-29-14-5-23(3)30(21-29)24-15-19-38(20-16-24)18-4-17-36-33(40)31(25-6-10-27(34)11-7-25)26-8-12-28(35)13-9-26/h5-14,21-22,24,31H,4,15-20H2,1-3H3,(H,36,40)(H,37,39)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219036 (CHEMBL388440 | N-{3-[1-(3-{[hydroxy(diphenyl)acety...) Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C(O)(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C33H41N3O3/c1-24(2)31(37)35-29-16-15-25(3)30(23-29)26-17-21-36(22-18-26)20-10-19-34-32(38)33(39,27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-16,23-24,26,39H,10,17-22H2,1-3H3,(H,34,38)(H,35,37)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219042 (CHEMBL242689 | N-[3-(1-{3-[(diphenylacetyl)amino]p...) Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C33H41N3O2/c1-24(2)32(37)35-29-16-15-25(3)30(23-29)26-17-21-36(22-18-26)20-10-19-34-33(38)31(27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-16,23-24,26,31H,10,17-22H2,1-3H3,(H,34,38)(H,35,37)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219035 (CHEMBL243355 | N-{5-[1-(3-{[bis(4-fluorophenyl)ace...) Show SMILES CC(C)C(=O)Nc1cc(C2CCN(CCCNC(=O)C(c3ccc(F)cc3)c3ccc(F)cc3)CC2)c(F)cc1F Show InChI InChI=1S/C32H35F4N3O2/c1-20(2)31(40)38-29-18-26(27(35)19-28(29)36)21-12-16-39(17-13-21)15-3-14-37-32(41)30(22-4-8-24(33)9-5-22)23-6-10-25(34)11-7-23/h4-11,18-21,30H,3,12-17H2,1-2H3,(H,37,41)(H,38,40)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219031 (1-(4-fluorophenyl)-N-(3-{4-[5-(isobutylamino)-2-me...) Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C2(CCCC2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C31H42FN3O2/c1-22(2)29(36)34-27-12-7-23(3)28(21-27)24-13-19-35(20-14-24)18-6-17-33-30(37)31(15-4-5-16-31)25-8-10-26(32)11-9-25/h7-12,21-22,24H,4-6,13-20H2,1-3H3,(H,33,37)(H,34,36)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219029 (CHEMBL390679 | N-{3-[1-(2-diphenylacetylamino-ethy...) Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCNC(=O)C(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C31H37N3O2/c1-23(2)30(35)33-28-15-9-14-27(22-28)24-16-19-34(20-17-24)21-18-32-31(36)29(25-10-5-3-6-11-25)26-12-7-4-8-13-26/h3-15,22-24,29H,16-21H2,1-2H3,(H,32,36)(H,33,35)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219039 ((2R)-2-(4-fluorophenyl)-N-(3-{4-[5-(isobutyrylamin...) Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@H](C)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C28H38FN3O2/c1-19(2)27(33)31-25-11-6-20(3)26(18-25)23-12-16-32(17-13-23)15-5-14-30-28(34)21(4)22-7-9-24(29)10-8-22/h6-11,18-19,21,23H,5,12-17H2,1-4H3,(H,30,34)(H,31,33)/t21-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219024 (2-methyl-N-{4-methyl-3-[1-(3-{[(2R)-2-phenylpropan...) Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@@H](C)c2ccccc2)CC1 Show InChI InChI=1S/C28H39N3O2/c1-20(2)27(32)30-25-12-11-21(3)26(19-25)24-13-17-31(18-14-24)16-8-15-29-28(33)22(4)23-9-6-5-7-10-23/h5-7,9-12,19-20,22,24H,8,13-18H2,1-4H3,(H,29,33)(H,30,32)/t22-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219028 (2-methyl-N-{4-methyl-3-[1-(3-{[(2S)-2-phenylpropan...) Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)[C@H](C)c2ccccc2)CC1 Show InChI InChI=1S/C28H39N3O2/c1-20(2)27(32)30-25-12-11-21(3)26(19-25)24-13-17-31(18-14-24)16-8-15-29-28(33)22(4)23-9-6-5-7-10-23/h5-7,9-12,19-20,22,24H,8,13-18H2,1-4H3,(H,29,33)(H,30,32)/t22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219032 (CHEMBL242902 | N-(3-{4-[3-(isobutyrylamino)phenyl]...) Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCNC(=O)C(C)(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C33H41N3O2/c1-25(2)31(37)35-30-17-10-12-27(24-30)26-18-22-36(23-19-26)21-11-20-34-32(38)33(3,28-13-6-4-7-14-28)29-15-8-5-9-16-29/h4-10,12-17,24-26H,11,18-23H2,1-3H3,(H,34,38)(H,35,37)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219037 (1-(4-fluorophenyl)-N-(3-{4-[5-(isobutyrylamino)-2-...) Show SMILES CC(C)C(=O)Nc1ccc(C)c(c1)C1CCN(CCCNC(=O)C2(CCCCC2)c2ccc(F)cc2)CC1 Show InChI InChI=1S/C32H44FN3O2/c1-23(2)30(37)35-28-13-8-24(3)29(22-28)25-14-20-36(21-15-25)19-7-18-34-31(38)32(16-5-4-6-17-32)26-9-11-27(33)12-10-26/h8-13,22-23,25H,4-7,14-21H2,1-3H3,(H,34,38)(H,35,37)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219041 (CHEMBL242901 | N-{3-[4-(3-isobutyrylamino-phenyl)-...) Show SMILES CCC(C(=O)NCCCN1CCC(CC1)c1cccc(NC(=O)C(C)C)c1)(c1ccccc1)c1ccccc1 Show InChI InChI=1S/C34H43N3O2/c1-4-34(29-14-7-5-8-15-29,30-16-9-6-10-17-30)33(39)35-21-12-22-37-23-19-27(20-24-37)28-13-11-18-31(25-28)36-32(38)26(2)3/h5-11,13-18,25-27H,4,12,19-24H2,1-3H3,(H,35,39)(H,36,38)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219034 (CHEMBL243129 | N-{3-[1-(6-diphenylacetylamino-hexy...) Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCCCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C35H45N3O2/c1-27(2)34(39)37-32-19-13-18-31(26-32)28-20-24-38(25-21-28)23-12-4-3-11-22-36-35(40)33(29-14-7-5-8-15-29)30-16-9-6-10-17-30/h5-10,13-19,26-28,33H,3-4,11-12,20-25H2,1-2H3,(H,36,40)(H,37,39)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219030 (CHEMBL243139 | N-{3-[1-(5-diphenylacetylamino-pent...) Show SMILES CC(C)C(=O)Nc1cccc(c1)C1CCN(CCCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C33H41N3O2/c1-25(2)32(37)35-30-17-11-16-29(24-30)26-18-22-36(23-19-26)21-10-9-20-34-33(38)31(27-12-5-3-6-13-27)28-14-7-4-8-15-28/h3-8,11-17,24-26,31H,9-10,18-23H2,1-2H3,(H,34,38)(H,35,37)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (RAT)	BDBM50219027 (CHEMBL388234 | N-{3-[1-(3-diphenylacetylamino-prop...) Show SMILES CC(C)C(=O)Nc1cc(ccc1C)C1CCN(CCCNC(=O)C(c2ccccc2)c2ccccc2)CC1 Show InChI InChI=1S/C33H41N3O2/c1-24(2)32(37)35-30-23-29(16-15-25(30)3)26-17-21-36(22-18-26)20-10-19-34-33(38)31(27-11-6-4-7-12-27)28-13-8-5-9-14-28/h4-9,11-16,23-24,26,31H,10,17-22H2,1-3H3,(H,34,38)(H,35,37)	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Lundbeck Research USA, Inc. Curated by ChEMBL					Assay Description Antagonist activity at rat MCHR1 expressed in HEK293 cells assessed as effect on calcium mobilization				J Med Chem 50: 3870-82 (2007) Article DOI: 10.1021/jm060381c BindingDB Entry DOI: 10.7270/Q2930SWM
					More data for this Ligand-Target Pair