Compile Data Set for Download or QSAR

Found 116 hits Enz. Inhib. hit(s) with all data for entry = 50021147   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221531 (6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)-4-...) Show SMILES COc1cc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2cc1OCCCN1CCN(C)CC1)C#N Show InChI InChI=1S/C28H33N5O2/c1-32-10-12-33(13-11-32)9-6-14-35-27-17-24-23(16-26(27)34-2)28(21(18-29)19-30-24)31-25-15-22(25)20-7-4-3-5-8-20/h3-5,7-8,16-17,19,22,25H,6,9-15H2,1-2H3,(H,30,31)/t22-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221516 (6-methoxy-7-(3-morpholinopropoxy)-4-((1R,2S)-2-phe...) Show SMILES COc1cc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2cc1OCCCN1CCOCC1)C#N Show InChI InChI=1S/C27H30N4O3/c1-32-25-15-22-23(16-26(25)34-11-5-8-31-9-12-33-13-10-31)29-18-20(17-28)27(22)30-24-14-21(24)19-6-3-2-4-7-19/h2-4,6-7,15-16,18,21,24H,5,8-14H2,1H3,(H,29,30)/t21-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221518 (6,7-dimethoxy-4-((1R,2S)-2-phenylcyclopropylamino)...) Show SMILES COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2cc1OC Show InChI InChI=1S/C21H19N3O2/c1-25-19-9-16-17(10-20(19)26-2)23-12-14(11-22)21(16)24-18-8-15(18)13-6-4-3-5-7-13/h3-7,9-10,12,15,18H,8H2,1-2H3,(H,23,24)/t15-,18+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50221531 (6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)-4-...) Show SMILES COc1cc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2cc1OCCCN1CCN(C)CC1)C#N Show InChI InChI=1S/C28H33N5O2/c1-32-10-12-33(13-11-32)9-6-14-35-27-17-24-23(16-26(27)34-2)28(21(18-29)19-30-24)31-25-15-22(25)20-7-4-3-5-8-20/h3-5,7-8,16-17,19,22,25H,6,9-15H2,1-2H3,(H,30,31)/t22-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of SRC				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221535 (4-((1R,2S)-2-(2-fluorophenyl)cyclopropylamino)-6,7...) Show SMILES COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3F)c2cc1OC Show InChI InChI=1S/C21H18FN3O2/c1-26-19-8-15-17(9-20(19)27-2)24-11-12(10-23)21(15)25-18-7-14(18)13-5-3-4-6-16(13)22/h3-6,8-9,11,14,18H,7H2,1-2H3,(H,24,25)/t14-,18+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221522 (6-(4-(aminomethyl)phenyl)-4-((1R,2S)-2-phenylcyclo...) Show SMILES NCc1ccc(cc1)-c1ccc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2c1 Show InChI InChI=1S/C26H22N4/c27-14-17-6-8-18(9-7-17)20-10-11-24-23(12-20)26(21(15-28)16-29-24)30-25-13-22(25)19-4-2-1-3-5-19/h1-12,16,22,25H,13-14,27H2,(H,29,30)/t22-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50221531 (6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)-4-...) Show SMILES COc1cc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2cc1OCCCN1CCN(C)CC1)C#N Show InChI InChI=1S/C28H33N5O2/c1-32-10-12-33(13-11-32)9-6-14-35-27-17-24-23(16-26(27)34-2)28(21(18-29)19-30-24)31-25-15-22(25)20-7-4-3-5-8-20/h3-5,7-8,16-17,19,22,25H,6,9-15H2,1-2H3,(H,30,31)/t22-,25+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	41	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of SYK				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221530 (6,7-diethyl-2-ethynyl-1-(((1S,2R)-2-p-tolylcyclopr...) Show SMILES COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccc(Cl)cc3)c2cc1OC Show InChI InChI=1S/C21H18ClN3O2/c1-26-19-8-16-17(9-20(19)27-2)24-11-13(10-23)21(16)25-18-7-15(18)12-3-5-14(22)6-4-12/h3-6,8-9,11,15,18H,7H2,1-2H3,(H,24,25)/t15-,18+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50221531 (6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)-4-...) Show SMILES COc1cc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2cc1OCCCN1CCN(C)CC1)C#N Show InChI InChI=1S/C28H33N5O2/c1-32-10-12-33(13-11-32)9-6-14-35-27-17-24-23(16-26(27)34-2)28(21(18-29)19-30-24)31-25-15-22(25)20-7-4-3-5-8-20/h3-5,7-8,16-17,19,22,25H,6,9-15H2,1-2H3,(H,30,31)/t22-,25+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of ABL				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50221516 (6-methoxy-7-(3-morpholinopropoxy)-4-((1R,2S)-2-phe...) Show SMILES COc1cc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2cc1OCCCN1CCOCC1)C#N Show InChI InChI=1S/C27H30N4O3/c1-32-25-15-22-23(16-26(25)34-11-5-8-31-9-12-33-13-10-31)29-18-20(17-28)27(22)30-24-14-21(24)19-6-3-2-4-7-19/h2-4,6-7,15-16,18,21,24H,5,8-14H2,1H3,(H,29,30)/t21-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of SRC				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50221524 (6-methoxy-4-((1R,2S)-2-phenylcyclopropylamino)-7-(...) Show SMILES COc1cc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2cc1OCCCc1cccnc1)C#N Show InChI InChI=1S/C28H26N4O2/c1-33-26-14-23-24(15-27(26)34-12-6-8-19-7-5-11-30-17-19)31-18-21(16-29)28(23)32-25-13-22(25)20-9-3-2-4-10-20/h2-5,7,9-11,14-15,17-18,22,25H,6,8,12-13H2,1H3,(H,31,32)/t22-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of SRC				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221527 (7-methoxy-6-(3-morpholinopropoxy)-4-((1R,2S)-2-phe...) Show SMILES COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2cc1OCCCN1CCOCC1 Show InChI InChI=1S/C27H30N4O3/c1-32-25-16-23-22(15-26(25)34-11-5-8-31-9-12-33-13-10-31)27(20(17-28)18-29-23)30-24-14-21(24)19-6-3-2-4-7-19/h2-4,6-7,15-16,18,21,24H,5,8-14H2,1H3,(H,29,30)/t21-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221533 (4-((1R,2S)-2-(3-bromophenyl)cyclopropylamino)-6,7-...) Show SMILES COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3cccc(Br)c3)c2cc1OC Show InChI InChI=1S/C21H18BrN3O2/c1-26-19-8-16-17(9-20(19)27-2)24-11-13(10-23)21(16)25-18-7-15(18)12-4-3-5-14(22)6-12/h3-6,8-9,11,15,18H,7H2,1-2H3,(H,24,25)/t15-,18+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221517 (6-methoxy-7-(2-methoxyethoxy)-4-((1R,2S)-2-phenylc...) Show SMILES COCCOc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2cc1OC Show InChI InChI=1S/C23H23N3O3/c1-27-8-9-29-22-12-19-18(11-21(22)28-2)23(16(13-24)14-25-19)26-20-10-17(20)15-6-4-3-5-7-15/h3-7,11-12,14,17,20H,8-10H2,1-2H3,(H,25,26)/t17-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221521 (7-methoxy-6-(2-morpholinoethoxy)-4-((1R,2S)-2-phen...) Show SMILES COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2cc1OCCN1CCOCC1 Show InChI InChI=1S/C26H28N4O3/c1-31-24-15-22-21(14-25(24)33-12-9-30-7-10-32-11-8-30)26(19(16-27)17-28-22)29-23-13-20(23)18-5-3-2-4-6-18/h2-6,14-15,17,20,23H,7-13H2,1H3,(H,28,29)/t20-,23+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	64	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221528 (7-methoxy-4-((1R,2S)-2-phenylcyclopropylamino)-6-(...) Show SMILES COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2cc1OCCCc1cccnc1 Show InChI InChI=1S/C28H26N4O2/c1-33-26-15-24-23(14-27(26)34-12-6-8-19-7-5-11-30-17-19)28(21(16-29)18-31-24)32-25-13-22(25)20-9-3-2-4-10-20/h2-5,7,9-11,14-15,17-18,22,25H,6,8,12-13H2,1H3,(H,31,32)/t22-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221532 (6,7-dimethoxy-4-((1R,2S)-2-(4-phenoxyphenyl)cyclop...) Show SMILES COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccc(Oc4ccccc4)cc3)c2cc1OC Show InChI InChI=1S/C27H23N3O3/c1-31-25-13-22-23(14-26(25)32-2)29-16-18(15-28)27(22)30-24-12-21(24)17-8-10-20(11-9-17)33-19-6-4-3-5-7-19/h3-11,13-14,16,21,24H,12H2,1-2H3,(H,29,30)/t21-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221529 (7-(4-(morpholinomethyl)phenyl)-4-((1R,2S)-2-phenyl...) Show SMILES N#Cc1cnc2cc(ccc2c1N[C@@H]1C[C@H]1c1ccccc1)-c1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C30H28N4O/c31-18-25-19-32-28-16-24(22-8-6-21(7-9-22)20-34-12-14-35-15-13-34)10-11-26(28)30(25)33-29-17-27(29)23-4-2-1-3-5-23/h1-11,16,19,27,29H,12-15,17,20H2,(H,32,33)/t27-,29+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50221522 (6-(4-(aminomethyl)phenyl)-4-((1R,2S)-2-phenylcyclo...) Show SMILES NCc1ccc(cc1)-c1ccc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2c1 Show InChI InChI=1S/C26H22N4/c27-14-17-6-8-18(9-7-17)20-10-11-24-23(12-20)26(21(15-28)16-29-24)30-25-13-22(25)19-4-2-1-3-5-19/h1-12,16,22,25H,13-14,27H2,(H,29,30)/t22-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of SRC				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50221524 (6-methoxy-4-((1R,2S)-2-phenylcyclopropylamino)-7-(...) Show SMILES COc1cc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2cc1OCCCc1cccnc1)C#N Show InChI InChI=1S/C28H26N4O2/c1-33-26-14-23-24(15-27(26)34-12-6-8-19-7-5-11-30-17-19)31-18-21(16-29)28(23)32-25-13-22(25)20-9-3-2-4-10-20/h2-5,7,9-11,14-15,17-18,22,25H,6,8,12-13H2,1H3,(H,31,32)/t22-,25+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	99	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50221517 (6-methoxy-7-(2-methoxyethoxy)-4-((1R,2S)-2-phenylc...) Show SMILES COCCOc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2cc1OC Show InChI InChI=1S/C23H23N3O3/c1-27-8-9-29-22-12-19-18(11-21(22)28-2)23(16(13-24)14-25-19)26-20-10-17(20)15-6-4-3-5-7-15/h3-7,11-12,14,17,20H,8-10H2,1-2H3,(H,25,26)/t17-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of SRC				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50221531 (6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)-4-...) Show SMILES COc1cc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2cc1OCCCN1CCN(C)CC1)C#N Show InChI InChI=1S/C28H33N5O2/c1-32-10-12-33(13-11-32)9-6-14-35-27-17-24-23(16-26(27)34-2)28(21(18-29)19-30-24)31-25-15-22(25)20-7-4-3-5-8-20/h3-5,7-8,16-17,19,22,25H,6,9-15H2,1-2H3,(H,30,31)/t22-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of Flt1				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221515 (6-(benzyloxy)-7-methoxy-4-((1R,2S)-2-phenylcyclopr...) Show SMILES COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2cc1OCc1ccccc1 Show InChI InChI=1S/C27H23N3O2/c1-31-25-14-23-22(13-26(25)32-17-18-8-4-2-5-9-18)27(20(15-28)16-29-23)30-24-12-21(24)19-10-6-3-7-11-19/h2-11,13-14,16,21,24H,12,17H2,1H3,(H,29,30)/t21-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50221517 (6-methoxy-7-(2-methoxyethoxy)-4-((1R,2S)-2-phenylc...) Show SMILES COCCOc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2cc1OC Show InChI InChI=1S/C23H23N3O3/c1-27-8-9-29-22-12-19-18(11-21(22)28-2)23(16(13-24)14-25-19)26-20-10-17(20)15-6-4-3-5-7-15/h3-7,11-12,14,17,20H,8-10H2,1-2H3,(H,25,26)/t17-,20+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50221524 (6-methoxy-4-((1R,2S)-2-phenylcyclopropylamino)-7-(...) Show SMILES COc1cc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2cc1OCCCc1cccnc1)C#N Show InChI InChI=1S/C28H26N4O2/c1-33-26-14-23-24(15-27(26)34-12-6-8-19-7-5-11-30-17-19)31-18-21(16-29)28(23)32-25-13-22(25)20-9-3-2-4-10-20/h2-5,7,9-11,14-15,17-18,22,25H,6,8,12-13H2,1H3,(H,31,32)/t22-,25+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of SYK				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50221529 (7-(4-(morpholinomethyl)phenyl)-4-((1R,2S)-2-phenyl...) Show SMILES N#Cc1cnc2cc(ccc2c1N[C@@H]1C[C@H]1c1ccccc1)-c1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C30H28N4O/c31-18-25-19-32-28-16-24(22-8-6-21(7-9-22)20-34-12-14-35-15-13-34)10-11-26(28)30(25)33-29-17-27(29)23-4-2-1-3-5-23/h1-11,16,19,27,29H,12-15,17,20H2,(H,32,33)/t27-,29+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of SRC				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50221518 (6,7-dimethoxy-4-((1R,2S)-2-phenylcyclopropylamino)...) Show SMILES COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2cc1OC Show InChI InChI=1S/C21H19N3O2/c1-25-19-9-16-17(10-20(19)26-2)23-12-14(11-22)21(16)24-18-8-15(18)13-6-4-3-5-7-13/h3-7,9-10,12,15,18H,8H2,1-2H3,(H,23,24)/t15-,18+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of SRC				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50221521 (7-methoxy-6-(2-morpholinoethoxy)-4-((1R,2S)-2-phen...) Show SMILES COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2cc1OCCN1CCOCC1 Show InChI InChI=1S/C26H28N4O3/c1-31-24-15-22-21(14-25(24)33-12-9-30-7-10-32-11-8-30)26(19(16-27)17-28-22)29-23-13-20(23)18-5-3-2-4-6-18/h2-6,14-15,17,20,23H,7-13H2,1H3,(H,28,29)/t20-,23+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50221517 (6-methoxy-7-(2-methoxyethoxy)-4-((1R,2S)-2-phenylc...) Show SMILES COCCOc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2cc1OC Show InChI InChI=1S/C23H23N3O3/c1-27-8-9-29-22-12-19-18(11-21(22)28-2)23(16(13-24)14-25-19)26-20-10-17(20)15-6-4-3-5-7-15/h3-7,11-12,14,17,20H,8-10H2,1-2H3,(H,25,26)/t17-,20+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of SYK				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50221529 (7-(4-(morpholinomethyl)phenyl)-4-((1R,2S)-2-phenyl...) Show SMILES N#Cc1cnc2cc(ccc2c1N[C@@H]1C[C@H]1c1ccccc1)-c1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C30H28N4O/c31-18-25-19-32-28-16-24(22-8-6-21(7-9-22)20-34-12-14-35-15-13-34)10-11-26(28)30(25)33-29-17-27(29)23-4-2-1-3-5-23/h1-11,16,19,27,29H,12-15,17,20H2,(H,32,33)/t27-,29+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50221523 (7-methoxy-4-((1R,2S)-2-phenylcyclopropylamino)quin...) Show SMILES COc1ccc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2c1)C#N Show InChI InChI=1S/C20H17N3O/c1-24-15-7-8-16-18(9-15)22-12-14(11-21)20(16)23-19-10-17(19)13-5-3-2-4-6-13/h2-9,12,17,19H,10H2,1H3,(H,22,23)/t17-,19+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	170	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of SRC				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221523 (7-methoxy-4-((1R,2S)-2-phenylcyclopropylamino)quin...) Show SMILES COc1ccc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2c1)C#N Show InChI InChI=1S/C20H17N3O/c1-24-15-7-8-16-18(9-15)22-12-14(11-21)20(16)23-19-10-17(19)13-5-3-2-4-6-13/h2-9,12,17,19H,10H2,1H3,(H,22,23)/t17-,19+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50221516 (6-methoxy-7-(3-morpholinopropoxy)-4-((1R,2S)-2-phe...) Show SMILES COc1cc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2cc1OCCCN1CCOCC1)C#N Show InChI InChI=1S/C27H30N4O3/c1-32-25-15-22-23(16-26(25)34-11-5-8-31-9-12-33-13-10-31)29-18-20(17-28)27(22)30-24-14-21(24)19-6-3-2-4-7-19/h2-4,6-7,15-16,18,21,24H,5,8-14H2,1H3,(H,29,30)/t21-,24+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of ABL				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50221526 (6-methoxy-4-((1R,2S)-2-phenylcyclopropylamino)quin...) Show SMILES COc1ccc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2c1 Show InChI InChI=1S/C20H17N3O/c1-24-15-7-8-18-17(9-15)20(14(11-21)12-22-18)23-19-10-16(19)13-5-3-2-4-6-13/h2-9,12,16,19H,10H2,1H3,(H,22,23)/t16-,19+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of SRC				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221524 (6-methoxy-4-((1R,2S)-2-phenylcyclopropylamino)-7-(...) Show SMILES COc1cc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2cc1OCCCc1cccnc1)C#N Show InChI InChI=1S/C28H26N4O2/c1-33-26-14-23-24(15-27(26)34-12-6-8-19-7-5-11-30-17-19)31-18-21(16-29)28(23)32-25-13-22(25)20-9-3-2-4-10-20/h2-5,7,9-11,14-15,17-18,22,25H,6,8,12-13H2,1H3,(H,31,32)/t22-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221534 (4-((1R,2S)-2-(4-bromophenyl)cyclopropylamino)-6,7-...) Show SMILES COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccc(Br)cc3)c2cc1OC Show InChI InChI=1S/C21H18BrN3O2/c1-26-19-8-16-17(9-20(19)27-2)24-11-13(10-23)21(16)25-18-7-15(18)12-3-5-14(22)6-4-12/h3-6,8-9,11,15,18H,7H2,1-2H3,(H,24,25)/t15-,18+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50221518 (6,7-dimethoxy-4-((1R,2S)-2-phenylcyclopropylamino)...) Show SMILES COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2cc1OC Show InChI InChI=1S/C21H19N3O2/c1-25-19-9-16-17(10-20(19)26-2)23-12-14(11-22)21(16)24-18-8-15(18)13-6-4-3-5-7-13/h3-7,9-10,12,15,18H,8H2,1-2H3,(H,23,24)/t15-,18+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of SYK				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50221520 (6-(3-(morpholinomethyl)phenyl)-4-((1R,2S)-2-phenyl...) Show SMILES N#Cc1cnc2ccc(cc2c1N[C@@H]1C[C@H]1c1ccccc1)-c1cccc(CN2CCOCC2)c1 Show InChI InChI=1S/C30H28N4O/c31-18-25-19-32-28-10-9-24(23-8-4-5-21(15-23)20-34-11-13-35-14-12-34)16-27(28)30(25)33-29-17-26(29)22-6-2-1-3-7-22/h1-10,15-16,19,26,29H,11-14,17,20H2,(H,32,33)/t26-,29+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of SRC				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50221529 (7-(4-(morpholinomethyl)phenyl)-4-((1R,2S)-2-phenyl...) Show SMILES N#Cc1cnc2cc(ccc2c1N[C@@H]1C[C@H]1c1ccccc1)-c1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C30H28N4O/c31-18-25-19-32-28-16-24(22-8-6-21(7-9-22)20-34-12-14-35-15-13-34)10-11-26(28)30(25)33-29-17-27(29)23-4-2-1-3-5-23/h1-11,16,19,27,29H,12-15,17,20H2,(H,32,33)/t27-,29+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of ABL				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase SYK (Homo sapiens (Human))	BDBM50221529 (7-(4-(morpholinomethyl)phenyl)-4-((1R,2S)-2-phenyl...) Show SMILES N#Cc1cnc2cc(ccc2c1N[C@@H]1C[C@H]1c1ccccc1)-c1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C30H28N4O/c31-18-25-19-32-28-16-24(22-8-6-21(7-9-22)20-34-12-14-35-15-13-34)10-11-26(28)30(25)33-29-17-27(29)23-4-2-1-3-5-23/h1-11,16,19,27,29H,12-15,17,20H2,(H,32,33)/t27-,29+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of SYK				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50221531 (6-methoxy-7-(3-(4-methylpiperazin-1-yl)propoxy)-4-...) Show SMILES COc1cc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2cc1OCCCN1CCN(C)CC1)C#N Show InChI InChI=1S/C28H33N5O2/c1-32-10-12-33(13-11-32)9-6-14-35-27-17-24-23(16-26(27)34-2)28(21(18-29)19-30-24)31-25-15-22(25)20-7-4-3-5-8-20/h3-5,7-8,16-17,19,22,25H,6,9-15H2,1-2H3,(H,30,31)/t22-,25+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50221524 (6-methoxy-4-((1R,2S)-2-phenylcyclopropylamino)-7-(...) Show SMILES COc1cc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2cc1OCCCc1cccnc1)C#N Show InChI InChI=1S/C28H26N4O2/c1-33-26-14-23-24(15-27(26)34-12-6-8-19-7-5-11-30-17-19)31-18-21(16-29)28(23)32-25-13-22(25)20-9-3-2-4-10-20/h2-5,7,9-11,14-15,17-18,22,25H,6,8,12-13H2,1H3,(H,31,32)/t22-,25+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of ABL				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50221515 (6-(benzyloxy)-7-methoxy-4-((1R,2S)-2-phenylcyclopr...) Show SMILES COc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2cc1OCc1ccccc1 Show InChI InChI=1S/C27H23N3O2/c1-31-25-14-23-22(13-26(25)32-17-18-8-4-2-5-9-18)27(20(15-28)16-29-23)30-24-12-21(24)19-10-6-3-7-11-19/h2-11,13-14,16,21,24H,12,17H2,1H3,(H,29,30)/t21-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of SRC				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221520 (6-(3-(morpholinomethyl)phenyl)-4-((1R,2S)-2-phenyl...) Show SMILES N#Cc1cnc2ccc(cc2c1N[C@@H]1C[C@H]1c1ccccc1)-c1cccc(CN2CCOCC2)c1 Show InChI InChI=1S/C30H28N4O/c31-18-25-19-32-28-10-9-24(23-8-4-5-21(15-23)20-34-11-13-35-14-12-34)16-27(28)30(25)33-29-17-26(29)22-6-2-1-3-7-22/h1-10,15-16,19,26,29H,11-14,17,20H2,(H,32,33)/t26-,29+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 1 (Homo sapiens (Human))	BDBM50221516 (6-methoxy-7-(3-morpholinopropoxy)-4-((1R,2S)-2-phe...) Show SMILES COc1cc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2cc1OCCCN1CCOCC1)C#N Show InChI InChI=1S/C27H30N4O3/c1-32-25-15-22-23(16-26(25)34-11-5-8-31-9-12-33-13-10-31)29-18-20(17-28)27(22)30-24-14-21(24)19-6-3-2-4-7-19/h2-4,6-7,15-16,18,21,24H,5,8-14H2,1H3,(H,29,30)/t21-,24+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of Flt1				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221526 (6-methoxy-4-((1R,2S)-2-phenylcyclopropylamino)quin...) Show SMILES COc1ccc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2c1 Show InChI InChI=1S/C20H17N3O/c1-24-15-7-8-18-17(9-15)20(14(11-21)12-22-18)23-19-10-16(19)13-5-3-2-4-6-13/h2-9,12,16,19H,10H2,1H3,(H,22,23)/t16-,19+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221519 (6-methoxy-7-(1-methylpiperidin-4-yloxy)-4-((1R,2S)...) Show SMILES COc1cc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2cc1OC1CCN(C)CC1)C#N Show InChI InChI=1S/C26H28N4O2/c1-30-10-8-19(9-11-30)32-25-14-22-21(13-24(25)31-2)26(18(15-27)16-28-22)29-23-12-20(23)17-6-4-3-5-7-17/h3-7,13-14,16,19-20,23H,8-12H2,1-2H3,(H,28,29)/t20-,23+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Homo sapiens (Human))	BDBM50221517 (6-methoxy-7-(2-methoxyethoxy)-4-((1R,2S)-2-phenylc...) Show SMILES COCCOc1cc2ncc(C#N)c(N[C@@H]3C[C@H]3c3ccccc3)c2cc1OC Show InChI InChI=1S/C23H23N3O3/c1-27-8-9-29-22-12-19-18(11-21(22)28-2)23(16(13-24)14-25-19)26-20-10-17(20)15-6-4-3-5-7-15/h3-7,11-12,14,17,20H,8-10H2,1-2H3,(H,25,26)/t17-,20+/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of ABL				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50221525 (6-(4-(morpholinomethyl)phenyl)-4-((1R,2S)-2-phenyl...) Show SMILES N#Cc1cnc2ccc(cc2c1N[C@@H]1C[C@H]1c1ccccc1)-c1ccc(CN2CCOCC2)cc1 Show InChI InChI=1S/C30H28N4O/c31-18-25-19-32-28-11-10-24(22-8-6-21(7-9-22)20-34-12-14-35-15-13-34)16-27(28)30(25)33-29-17-26(29)23-4-2-1-3-5-23/h1-11,16,19,26,29H,12-15,17,20H2,(H,32,33)/t26-,29+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant EGFR by fluorescence polarization assay				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50221516 (6-methoxy-7-(3-morpholinopropoxy)-4-((1R,2S)-2-phe...) Show SMILES COc1cc2c(N[C@@H]3C[C@H]3c3ccccc3)c(cnc2cc1OCCCN1CCOCC1)C#N Show InChI InChI=1S/C27H30N4O3/c1-32-25-15-22-23(16-26(25)34-11-5-8-31-9-12-33-13-10-31)29-18-20(17-28)27(22)30-24-14-21(24)19-6-3-2-4-7-19/h2-4,6-7,15-16,18,21,24H,5,8-14H2,1H3,(H,29,30)/t21-,24+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA, Inc. Curated by ChEMBL					Assay Description Inhibition of KDR				Bioorg Med Chem Lett 17: 5978-82 (2007) Article DOI: 10.1016/j.bmcl.2007.07.071 BindingDB Entry DOI: 10.7270/Q2VM4C0N
					More data for this Ligand-Target Pair

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