Compile Data Set for Download or QSAR

Found 30 hits Enz. Inhib. hit(s) with all data for entry = 50021240   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222500 (CHEMBL250482 | N-(4-cyclohexylphenyl)-2-(pyridin-4...) Show SMILES O=C(Nc1ccc(cc1)C1CCCCC1)c1cccnc1NCc1ccncc1 Show InChI InChI=1S/C24H26N4O/c29-24(28-21-10-8-20(9-11-21)19-5-2-1-3-6-19)22-7-4-14-26-23(22)27-17-18-12-15-25-16-13-18/h4,7-16,19H,1-3,5-6,17H2,(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222499 (CHEMBL401153 | N-(3-chlorophenyl)-2-(pyridin-4-ylm...) Show SMILES Clc1cccc(NC(=O)c2cccnc2NCc2ccncc2)c1 Show InChI InChI=1S/C18H15ClN4O/c19-14-3-1-4-15(11-14)23-18(24)16-5-2-8-21-17(16)22-12-13-6-9-20-10-7-13/h1-11H,12H2,(H,21,22)(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222501 (CHEMBL250684 | N-(4-chloro-3-(trifluoromethyl)phen...) Show SMILES FC(F)(F)c1cc(NC(=O)c2cccnc2NCc2ccncc2)ccc1Cl Show InChI InChI=1S/C19H14ClF3N4O/c20-16-4-3-13(10-15(16)19(21,22)23)27-18(28)14-2-1-7-25-17(14)26-11-12-5-8-24-9-6-12/h1-10H,11H2,(H,25,26)(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222498 (CHEMBL400512 | N-(3,5-bis(trifluoromethyl)phenyl)-...) Show SMILES FC(F)(F)c1cc(NC(=O)c2cccnc2NCc2ccncc2)cc(c1)C(F)(F)F Show InChI InChI=1S/C20H14F6N4O/c21-19(22,23)13-8-14(20(24,25)26)10-15(9-13)30-18(31)16-2-1-5-28-17(16)29-11-12-3-6-27-7-4-12/h1-10H,11H2,(H,28,29)(H,30,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222509 (CHEMBL250228 | N-(4-chlorophenyl)-2-(pyridin-4-ylm...) Show SMILES Clc1ccc(NC(=O)c2cccnc2NCc2ccncc2)cc1 Show InChI InChI=1S/C18H15ClN4O/c19-14-3-5-15(6-4-14)23-18(24)16-2-1-9-21-17(16)22-12-13-7-10-20-11-8-13/h1-11H,12H2,(H,21,22)(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of unphosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222512 (2-(pyridin-4-ylmethylamino)-N-(4-(trifluoromethyl)...) Show SMILES FC(F)(F)c1ccc(NC(=O)c2cccnc2NCc2ccncc2)cc1 Show InChI InChI=1S/C19H15F3N4O/c20-19(21,22)14-3-5-15(6-4-14)26-18(27)16-2-1-9-24-17(16)25-12-13-7-10-23-11-8-13/h1-11H,12H2,(H,24,25)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM15019 (CHEMBL385178 | N-(4-phenoxyphenyl)-2-[(pyridin-4-y...) Show SMILES O=C(Nc1ccc(Oc2ccccc2)cc1)c1cccnc1NCc1ccncc1 Show InChI InChI=1S/C24H20N4O2/c29-24(22-7-4-14-26-23(22)27-17-18-12-15-25-16-13-18)28-19-8-10-21(11-9-19)30-20-5-2-1-3-6-20/h1-16H,17H2,(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair				3D Structure (crystal)
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50132151 (CHEMBL101683 | N-(4-Chloro-phenyl)-2-[(pyridin-4-y...) Show SMILES Clc1ccc(NC(=O)c2ccccc2NCc2ccncc2)cc1 Show InChI InChI=1S/C19H16ClN3O/c20-15-5-7-16(8-6-15)23-19(24)17-3-1-2-4-18(17)22-13-14-9-11-21-12-10-14/h1-12,22H,13H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222513 (CHEMBL248781 | N-(3,4-dichlorophenyl)-2-(pyridin-4...) Show SMILES Clc1ccc(NC(=O)c2cccnc2NCc2ccncc2)cc1Cl Show InChI InChI=1S/C18H14Cl2N4O/c19-15-4-3-13(10-16(15)20)24-18(25)14-2-1-7-22-17(14)23-11-12-5-8-21-9-6-12/h1-10H,11H2,(H,22,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222516 (CHEMBL400140 | N-(4-butylphenyl)-2-(pyridin-4-ylme...) Show SMILES CCCCc1ccc(NC(=O)c2cccnc2NCc2ccncc2)cc1 Show InChI InChI=1S/C22H24N4O/c1-2-3-5-17-7-9-19(10-8-17)26-22(27)20-6-4-13-24-21(20)25-16-18-11-14-23-15-12-18/h4,6-15H,2-3,5,16H2,1H3,(H,24,25)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222503 (CHEMBL248976 | N-biphenyl-4-yl-2-[(pyridin-4-ylmet...) Show SMILES O=C(Nc1ccc(cc1)-c1ccccc1)c1cccnc1NCc1ccncc1 Show InChI InChI=1S/C24H20N4O/c29-24(28-21-10-8-20(9-11-21)19-5-2-1-3-6-19)22-7-4-14-26-23(22)27-17-18-12-15-25-16-13-18/h1-16H,17H2,(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222517 (2-(pyridin-4-ylmethylamino)-N-(4-(trifluoromethoxy...) Show SMILES FC(F)(F)Oc1ccc(NC(=O)c2cccnc2NCc2ccncc2)cc1 Show InChI InChI=1S/C19H15F3N4O2/c20-19(21,22)28-15-5-3-14(4-6-15)26-18(27)16-2-1-9-24-17(16)25-12-13-7-10-23-11-8-13/h1-11H,12H2,(H,24,25)(H,26,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222504 (CHEMBL249192 | ethyl 5-(3-(2-(pyridin-4-ylmethylam...) Show SMILES CCOC(=O)c1coc(c1)-c1cccc(NC(=O)c2cccnc2NCc2ccncc2)c1 Show InChI InChI=1S/C25H22N4O4/c1-2-32-25(31)19-14-22(33-16-19)18-5-3-6-20(13-18)29-24(30)21-7-4-10-27-23(21)28-15-17-8-11-26-12-9-17/h3-14,16H,2,15H2,1H3,(H,27,28)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222508 (2-(benzo[d][1,3]dioxol-5-ylmethylamino)-N-(4-pheno...) Show SMILES O=C(Nc1ccc(Oc2ccccc2)cc1)c1cccnc1NCc1ccc2OCOc2c1 Show InChI InChI=1S/C26H21N3O4/c30-26(29-19-9-11-21(12-10-19)33-20-5-2-1-3-6-20)22-7-4-14-27-25(22)28-16-18-8-13-23-24(15-18)32-17-31-23/h1-15H,16-17H2,(H,27,28)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222496 (2-(1H-indazol-6-ylamino)-N-(4-phenoxyphenyl)nicoti...) Show SMILES O=C(Nc1ccc(Oc2ccccc2)cc1)c1cccnc1Nc1ccc2cn[nH]c2c1 Show InChI InChI=1S/C25H19N5O2/c31-25(29-18-10-12-21(13-11-18)32-20-5-2-1-3-6-20)22-7-4-14-26-24(22)28-19-9-8-17-16-27-30-23(17)15-19/h1-16H,(H,26,28)(H,27,30)(H,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222507 (CHEMBL399546 | N-biphenyl-3-yl-2-[(pyridin-4-ylmet...) Show SMILES O=C(Nc1cccc(c1)-c1ccccc1)c1cccnc1NCc1ccncc1 Show InChI InChI=1S/C24H20N4O/c29-24(28-21-9-4-8-20(16-21)19-6-2-1-3-7-19)22-10-5-13-26-23(22)27-17-18-11-14-25-15-12-18/h1-16H,17H2,(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222520 (CHEMBL248980 | N-(3-ethylphenyl)-2-(pyridin-4-ylme...) Show SMILES CCc1cccc(NC(=O)c2cccnc2NCc2ccncc2)c1 Show InChI InChI=1S/C20H20N4O/c1-2-15-5-3-6-17(13-15)24-20(25)18-7-4-10-22-19(18)23-14-16-8-11-21-12-9-16/h3-13H,2,14H2,1H3,(H,22,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	106	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222497 (CHEMBL250842 | N-(4-chlorophenyl)-3-(pyridin-4-ylm...) Show SMILES Clc1ccc(NC(=O)c2sccc2NCc2ccncc2)cc1 Show InChI InChI=1S/C17H14ClN3OS/c18-13-1-3-14(4-2-13)21-17(22)16-15(7-10-23-16)20-11-12-5-8-19-9-6-12/h1-10,20H,11H2,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of unphosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222522 (2-(4-fluorophenylamino)-N-(4-phenoxyphenyl)nicotin...) Show SMILES Fc1ccc(Nc2ncccc2C(=O)Nc2ccc(Oc3ccccc3)cc2)cc1 Show InChI InChI=1S/C24H18FN3O2/c25-17-8-10-18(11-9-17)27-23-22(7-4-16-26-23)24(29)28-19-12-14-21(15-13-19)30-20-5-2-1-3-6-20/h1-16H,(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	135	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222519 (CHEMBL250665 | N-(4-chlorophenyl)-4-(pyridin-4-ylm...) Show SMILES Clc1ccc(NC(=O)c2cncnc2NCc2ccncc2)cc1 Show InChI InChI=1S/C17H14ClN5O/c18-13-1-3-14(4-2-13)23-17(24)15-10-20-11-22-16(15)21-9-12-5-7-19-8-6-12/h1-8,10-11H,9H2,(H,23,24)(H,20,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222510 (CHEMBL249194 | N-(3-phenoxyphenyl)-2-(pyridin-4-yl...) Show SMILES O=C(Nc1cccc(Oc2ccccc2)c1)c1cccnc1NCc1ccncc1 Show InChI InChI=1S/C24H20N4O2/c29-24(22-10-5-13-26-23(22)27-17-18-11-14-25-15-12-18)28-19-6-4-9-21(16-19)30-20-7-2-1-3-8-20/h1-16H,17H2,(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	259	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222515 (2-(pyridin-4-ylmethylamino)-N-p-tolylnicotinamide ...) Show SMILES Cc1ccc(NC(=O)c2cccnc2NCc2ccncc2)cc1 Show InChI InChI=1S/C19H18N4O/c1-14-4-6-16(7-5-14)23-19(24)17-3-2-10-21-18(17)22-13-15-8-11-20-12-9-15/h2-12H,13H2,1H3,(H,21,22)(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	320	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222523 (5-bromo-N-(4-chlorophenyl)-2-(pyridin-4-ylmethylam...) Show SMILES Clc1ccc(NC(=O)c2cc(Br)cnc2NCc2ccncc2)cc1 Show InChI InChI=1S/C18H14BrClN4O/c19-13-9-16(18(25)24-15-3-1-14(20)2-4-15)17(23-11-13)22-10-12-5-7-21-8-6-12/h1-9,11H,10H2,(H,22,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	490	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222514 (CHEMBL249599 | N-(3-(1-hydroxyethyl)phenyl)-2-(pyr...) Show SMILES CC(O)c1cccc(NC(=O)c2cccnc2NCc2ccncc2)c1 |w:1.0| Show InChI InChI=1S/C20H20N4O2/c1-14(25)16-4-2-5-17(12-16)24-20(26)18-6-3-9-22-19(18)23-13-15-7-10-21-11-8-15/h2-12,14,25H,13H2,1H3,(H,22,23)(H,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>6.66E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222506 (CHEMBL400102 | N-(4-(4-methylpiperazin-1-yl)phenyl...) Show SMILES CN1CCN(CC1)c1ccc(NC(=O)c2cccnc2NCc2ccncc2)cc1 Show InChI InChI=1S/C23H26N6O/c1-28-13-15-29(16-14-28)20-6-4-19(5-7-20)27-23(30)21-3-2-10-25-22(21)26-17-18-8-11-24-12-9-18/h2-12H,13-17H2,1H3,(H,25,26)(H,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>6.66E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222505 (CHEMBL250472 | N-(4-chlorophenyl)-3-(pyridin-4-ylm...) Show SMILES Clc1ccc(NC(=O)c2ncccc2NCc2ccncc2)cc1 Show InChI InChI=1S/C18H15ClN4O/c19-14-3-5-15(6-4-14)23-18(24)17-16(2-1-9-21-17)22-12-13-7-10-20-11-8-13/h1-11,22H,12H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222511 (CHEMBL400584 | N-(4-chlorophenyl)-2-(pyridin-4-ylm...) Show SMILES Clc1ccc(NC(=O)C2CCCCC2NCc2ccncc2)cc1 |w:8.7,13.14| Show InChI InChI=1S/C19H22ClN3O/c20-15-5-7-16(8-6-15)23-19(24)17-3-1-2-4-18(17)22-13-14-9-11-21-12-10-14/h5-12,17-18,22H,1-4,13H2,(H,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222521 (CHEMBL250470 | N-(4-chlorophenyl)-6-methyl-2-(pyri...) Show SMILES Cc1ccc(C(=O)Nc2ccc(Cl)cc2)c(NCc2ccncc2)n1 Show InChI InChI=1S/C19H17ClN4O/c1-13-2-7-17(19(25)24-16-5-3-15(20)4-6-16)18(23-13)22-12-14-8-10-21-11-9-14/h2-11H,12H2,1H3,(H,22,23)(H,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of unphosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222518 (2-(benzo[b]thiophen-3-ylamino)-N-(4-phenoxyphenyl)...) Show SMILES O=C(Nc1ccc(Oc2ccccc2)cc1)c1cccnc1Nc1csc2ccccc12 Show InChI InChI=1S/C26H19N3O2S/c30-26(28-18-12-14-20(15-13-18)31-19-7-2-1-3-8-19)22-10-6-16-27-25(22)29-23-17-32-24-11-5-4-9-21(23)24/h1-17H,(H,27,29)(H,28,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50222502 (CHEMBL249606 | N-(2-phenoxyphenyl)-2-(pyridin-4-yl...) Show SMILES O=C(Nc1ccccc1Oc1ccccc1)c1cccnc1NCc1ccncc1 Show InChI InChI=1S/C24H20N4O2/c29-24(20-9-6-14-26-23(20)27-17-18-12-15-25-16-13-18)28-21-10-4-5-11-22(21)30-19-7-2-1-3-8-19/h1-16H,17H2,(H,26,27)(H,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Amgen Curated by ChEMBL					Assay Description Inhibition of phosphorylated-Kdr after 30 mins				Bioorg Med Chem Lett 17: 6003-8 (2007) Article DOI: 10.1016/j.bmcl.2007.07.077 BindingDB Entry DOI: 10.7270/Q27P8Z3N
					More data for this Ligand-Target Pair