Compile Data Set for Download or QSAR

Found 107 hits Enz. Inhib. hit(s) with all data for entry = 50021541   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225589 ((4-(1-((3-fluoro-4-methoxybenzylamino)methyl)cyclo...) Show SMILES COc1ccc(CNCC2(CCCCC2)N2CCN(CC2)C(=O)[C@H]2CN(C[C@@H]2c2ccc(Cl)cc2)C(C)C)cc1F Show InChI InChI=1S/C33H46ClFN4O2/c1-24(2)38-21-28(26-8-10-27(34)11-9-26)29(22-38)32(40)37-15-17-39(18-16-37)33(13-5-4-6-14-33)23-36-20-25-7-12-31(41-3)30(35)19-25/h7-12,19,24,28-29,36H,4-6,13-18,20-23H2,1-3H3/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Mus musculus)	BDBM50225589 ((4-(1-((3-fluoro-4-methoxybenzylamino)methyl)cyclo...) Show SMILES COc1ccc(CNCC2(CCCCC2)N2CCN(CC2)C(=O)[C@H]2CN(C[C@@H]2c2ccc(Cl)cc2)C(C)C)cc1F Show InChI InChI=1S/C33H46ClFN4O2/c1-24(2)38-21-28(26-8-10-27(34)11-9-26)29(22-38)32(40)37-15-17-39(18-16-37)33(13-5-4-6-14-33)23-36-20-25-7-12-31(41-3)30(35)19-25/h7-12,19,24,28-29,36H,4-6,13-18,20-23H2,1-3H3/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Binding affinity to mouse MC4R				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225593 ((4-(1-((2-fluoro-4-methoxybenzylamino)methyl)cyclo...) Show SMILES COc1ccc(CNCC2(CCCCC2)N2CCN(CC2)C(=O)[C@H]2CN(C[C@@H]2c2ccc(Cl)cc2)C(C)C)c(F)c1 Show InChI InChI=1S/C33H46ClFN4O2/c1-24(2)38-21-29(25-7-10-27(34)11-8-25)30(22-38)32(40)37-15-17-39(18-16-37)33(13-5-4-6-14-33)23-36-20-26-9-12-28(41-3)19-31(26)35/h7-12,19,24,29-30,36H,4-6,13-18,20-23H2,1-3H3/t29-,30+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225588 ((4-(1-((4-isopropoxybenzylamino)methyl)cyclohexyl)...) Show SMILES CC(C)Oc1ccc(CNCC2(CCCCC2)N2CCN(CC2)C(=O)[C@H]2CN(C[C@@H]2c2ccc(Cl)cc2)C(C)C)cc1 Show InChI InChI=1S/C35H51ClN4O2/c1-26(2)39-23-32(29-10-12-30(36)13-11-29)33(24-39)34(41)38-18-20-40(21-19-38)35(16-6-5-7-17-35)25-37-22-28-8-14-31(15-9-28)42-27(3)4/h8-15,26-27,32-33,37H,5-7,16-25H2,1-4H3/t32-,33+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225618 ((4-(1-((4-methoxybenzylamino)methyl)cyclohexyl)pip...) Show SMILES COc1ccc(CNCC2(CCCCC2)N2CCN(CC2)C(=O)[C@H]2CN(C[C@@H]2c2ccc(Cl)cc2)C(C)C)cc1 Show InChI InChI=1S/C33H47ClN4O2/c1-25(2)37-22-30(27-9-11-28(34)12-10-27)31(23-37)32(39)36-17-19-38(20-18-36)33(15-5-4-6-16-33)24-35-21-26-7-13-29(40-3)14-8-26/h7-14,25,30-31,35H,4-6,15-24H2,1-3H3/t30-,31+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225601 ((4-(1-((benzylamino)methyl)cyclohexyl)piperazin-1-...) Show SMILES Clc1ccc(cc1)[C@H]1CN(C[C@@H]1C(=O)N1CCN(CC1)C1(CNCc2ccccc2)CCCCC1)C1CCCCC1 Show InChI InChI=1S/C35H49ClN4O/c36-30-16-14-29(15-17-30)32-25-39(31-12-6-2-7-13-31)26-33(32)34(41)38-20-22-40(23-21-38)35(18-8-3-9-19-35)27-37-24-28-10-4-1-5-11-28/h1,4-5,10-11,14-17,31-33,37H,2-3,6-9,12-13,18-27H2/t32-,33+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225648 ((4-(1-((benzo[d][1,3]dioxol-5-ylmethylamino)methyl...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccc3OCOc3c2)CCCCC1 Show InChI InChI=1S/C33H45ClN4O3/c1-24(2)37-20-28(26-7-9-27(34)10-8-26)29(21-37)32(39)36-14-16-38(17-15-36)33(12-4-3-5-13-33)22-35-19-25-6-11-30-31(18-25)41-23-40-30/h6-11,18,24,28-29,35H,3-5,12-17,19-23H2,1-2H3/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225638 ((4-(1-((2,4-difluorobenzylamino)methyl)cyclohexyl)...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccc(F)cc2F)CCCCC1 Show InChI InChI=1S/C32H43ClF2N4O/c1-23(2)38-20-28(24-6-9-26(33)10-7-24)29(21-38)31(40)37-14-16-39(17-15-37)32(12-4-3-5-13-32)22-36-19-25-8-11-27(34)18-30(25)35/h6-11,18,23,28-29,36H,3-5,12-17,19-22H2,1-2H3/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225586 ((4-(1-(((1,5-dimethyl-1H-pyrazol-4-yl)methylamino)...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccccc1)C(=O)N1CCN(CC1)C1(CNCc2cnn(C)c2C)CCCCC1 Show InChI InChI=1S/C31H48N6O/c1-24(2)36-21-28(26-11-7-5-8-12-26)29(22-36)30(38)35-15-17-37(18-16-35)31(13-9-6-10-14-31)23-32-19-27-20-33-34(4)25(27)3/h5,7-8,11-12,20,24,28-29,32H,6,9-10,13-19,21-23H2,1-4H3/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225583 ((4-(1-((2-fluorobenzylamino)methyl)cyclohexyl)pipe...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccccc2F)CCCCC1 Show InChI InChI=1S/C32H44ClFN4O/c1-24(2)37-21-28(25-10-12-27(33)13-11-25)29(22-37)31(39)36-16-18-38(19-17-36)32(14-6-3-7-15-32)23-35-20-26-8-4-5-9-30(26)34/h4-5,8-13,24,28-29,35H,3,6-7,14-23H2,1-2H3/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225584 ((4-(1-((2,4-dimethoxybenzylamino)methyl)cyclohexyl...) Show SMILES COc1ccc(CNCC2(CCCCC2)N2CCN(CC2)C(=O)[C@H]2CN(C[C@@H]2c2ccc(Cl)cc2)C(C)C)c(OC)c1 Show InChI InChI=1S/C34H49ClN4O3/c1-25(2)38-22-30(26-8-11-28(35)12-9-26)31(23-38)33(40)37-16-18-39(19-17-37)34(14-6-5-7-15-34)24-36-21-27-10-13-29(41-3)20-32(27)42-4/h8-13,20,25,30-31,36H,5-7,14-19,21-24H2,1-4H3/t30-,31+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225634 ((4-(1-((benzylamino)methyl)cyclohexyl)piperazin-1-...) Show SMILES Clc1ccc(cc1)[C@H]1CN(C[C@@H]1C(=O)N1CCN(CC1)C1(CNCc2ccccc2)CCCCC1)C1CCCC1 Show InChI InChI=1S/C34H47ClN4O/c35-29-15-13-28(14-16-29)31-24-38(30-11-5-6-12-30)25-32(31)33(40)37-19-21-39(22-20-37)34(17-7-2-8-18-34)26-36-23-27-9-3-1-4-10-27/h1,3-4,9-10,13-16,30-32,36H,2,5-8,11-12,17-26H2/t31-,32+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225616 (((3R,4S)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccsc2)CCCCC1 Show InChI InChI=1S/C30H43ClN4OS/c1-23(2)34-19-27(25-6-8-26(31)9-7-25)28(20-34)29(36)33-13-15-35(16-14-33)30(11-4-3-5-12-30)22-32-18-24-10-17-37-21-24/h6-10,17,21,23,27-28,32H,3-5,11-16,18-20,22H2,1-2H3/t27-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225587 ((4-(1-((3-fluorobenzylamino)methyl)cyclohexyl)pipe...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2cccc(F)c2)CCCCC1 Show InChI InChI=1S/C32H44ClFN4O/c1-24(2)37-21-29(26-9-11-27(33)12-10-26)30(22-37)31(39)36-15-17-38(18-16-36)32(13-4-3-5-14-32)23-35-20-25-7-6-8-28(34)19-25/h6-12,19,24,29-30,35H,3-5,13-18,20-23H2,1-2H3/t29-,30+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225613 ((4-(1-((2-chlorobenzylamino)methyl)cyclohexyl)pipe...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccccc2Cl)CCCCC1 Show InChI InChI=1S/C32H44Cl2N4O/c1-24(2)37-21-28(25-10-12-27(33)13-11-25)29(22-37)31(39)36-16-18-38(19-17-36)32(14-6-3-7-15-32)23-35-20-26-8-4-5-9-30(26)34/h4-5,8-13,24,28-29,35H,3,6-7,14-23H2,1-2H3/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225598 ((4-(1-((benzylamino)methyl)cyclohexyl)piperazin-1-...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccccc2)CCCCC1 Show InChI InChI=1S/C32H45ClN4O/c1-25(2)36-22-29(27-11-13-28(33)14-12-27)30(23-36)31(38)35-17-19-37(20-18-35)32(15-7-4-8-16-32)24-34-21-26-9-5-3-6-10-26/h3,5-6,9-14,25,29-30,34H,4,7-8,15-24H2,1-2H3/t29-,30+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	26	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225611 (((3R,4S)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccncc2)CCCCC1 Show InChI InChI=1S/C31H44ClN5O/c1-24(2)36-21-28(26-6-8-27(32)9-7-26)29(22-36)30(38)35-16-18-37(19-17-35)31(12-4-3-5-13-31)23-34-20-25-10-14-33-15-11-25/h6-11,14-15,24,28-29,34H,3-5,12-13,16-23H2,1-2H3/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225623 ((4-(1-((4-(methylthio)benzylamino)methyl)cyclohexy...) Show SMILES CSc1ccc(CNCC2(CCCCC2)N2CCN(CC2)C(=O)[C@H]2CN(C[C@@H]2c2ccc(Cl)cc2)C(C)C)cc1 Show InChI InChI=1S/C33H47ClN4OS/c1-25(2)37-22-30(27-9-11-28(34)12-10-27)31(23-37)32(39)36-17-19-38(20-18-36)33(15-5-4-6-16-33)24-35-21-26-7-13-29(40-3)14-8-26/h7-14,25,30-31,35H,4-6,15-24H2,1-3H3/t30-,31+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225603 (CHEMBL400263 | N-(4-(((1-(4-((3S,4R)-3-(4-chloroph...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccc(NC(C)=O)cc2)CCCCC1 Show InChI InChI=1S/C34H48ClN5O2/c1-25(2)39-22-31(28-9-11-29(35)12-10-28)32(23-39)33(42)38-17-19-40(20-18-38)34(15-5-4-6-16-34)24-36-21-27-7-13-30(14-8-27)37-26(3)41/h7-14,25,31-32,36H,4-6,15-24H2,1-3H3,(H,37,41)/t31-,32+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225602 ((4-(1-((benzylamino)methyl)cyclohexyl)piperazin-1-...) Show SMILES Clc1ccc(cc1)[C@H]1CN(C[C@@H]1C(=O)N1CCN(CC1)C1(CNCc2ccccc2)CCCCC1)C1CCOCC1 Show InChI InChI=1S/C34H47ClN4O2/c35-29-11-9-28(10-12-29)31-24-38(30-13-21-41-22-14-30)25-32(31)33(40)37-17-19-39(20-18-37)34(15-5-2-6-16-34)26-36-23-27-7-3-1-4-8-27/h1,3-4,7-12,30-32,36H,2,5-6,13-26H2/t31-,32+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225626 ((4-(1-((3-methoxybenzylamino)methyl)cyclohexyl)pip...) Show SMILES COc1cccc(CNCC2(CCCCC2)N2CCN(CC2)C(=O)[C@H]2CN(C[C@@H]2c2ccc(Cl)cc2)C(C)C)c1 Show InChI InChI=1S/C33H47ClN4O2/c1-25(2)37-22-30(27-10-12-28(34)13-11-27)31(23-37)32(39)36-16-18-38(19-17-36)33(14-5-4-6-15-33)24-35-21-26-8-7-9-29(20-26)40-3/h7-13,20,25,30-31,35H,4-6,14-19,21-24H2,1-3H3/t30-,31+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225650 (CHEMBL249270 | methyl 4-(((1-(4-((3S,4R)-3-(4-chlo...) Show SMILES COC(=O)c1ccc(CNCC2(CCCCC2)N2CCN(CC2)C(=O)[C@H]2CN(C[C@@H]2c2ccc(Cl)cc2)C(C)C)cc1 Show InChI InChI=1S/C34H47ClN4O3/c1-25(2)38-22-30(27-11-13-29(35)14-12-27)31(23-38)32(40)37-17-19-39(20-18-37)34(15-5-4-6-16-34)24-36-21-26-7-9-28(10-8-26)33(41)42-3/h7-14,25,30-31,36H,4-6,15-24H2,1-3H3/t30-,31+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225620 (((3R,4S)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2cccnc2)CCCCC1 Show InChI InChI=1S/C31H44ClN5O/c1-24(2)36-21-28(26-8-10-27(32)11-9-26)29(22-36)30(38)35-15-17-37(18-16-35)31(12-4-3-5-13-31)23-34-20-25-7-6-14-33-19-25/h6-11,14,19,24,28-29,34H,3-5,12-13,15-18,20-23H2,1-2H3/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225644 (((3R,4S)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2cccs2)CCCCC1 Show InChI InChI=1S/C30H43ClN4OS/c1-23(2)34-20-27(24-8-10-25(31)11-9-24)28(21-34)29(36)33-14-16-35(17-15-33)30(12-4-3-5-13-30)22-32-19-26-7-6-18-37-26/h6-11,18,23,27-28,32H,3-5,12-17,19-22H2,1-2H3/t27-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225645 (((3R,4S)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccco2)CCCCC1 Show InChI InChI=1S/C30H43ClN4O2/c1-23(2)34-20-27(24-8-10-25(31)11-9-24)28(21-34)29(36)33-14-16-35(17-15-33)30(12-4-3-5-13-30)22-32-19-26-7-6-18-37-26/h6-11,18,23,27-28,32H,3-5,12-17,19-22H2,1-2H3/t27-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225627 ((4-(1-((4-fluorobenzylamino)methyl)cyclohexyl)pipe...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccc(F)cc2)CCCCC1 Show InChI InChI=1S/C32H44ClFN4O/c1-24(2)37-21-29(26-8-10-27(33)11-9-26)30(22-37)31(39)36-16-18-38(19-17-36)32(14-4-3-5-15-32)23-35-20-25-6-12-28(34)13-7-25/h6-13,24,29-30,35H,3-5,14-23H2,1-2H3/t29-,30+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	44	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225619 ((4-(1-((4-nitrobenzylamino)methyl)cyclohexyl)piper...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccc(cc2)[N+]([O-])=O)CCCCC1 Show InChI InChI=1S/C32H44ClN5O3/c1-24(2)36-21-29(26-8-10-27(33)11-9-26)30(22-36)31(39)35-16-18-37(19-17-35)32(14-4-3-5-15-32)23-34-20-25-6-12-28(13-7-25)38(40)41/h6-13,24,29-30,34H,3-5,14-23H2,1-2H3/t29-,30+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225590 ((4-(1-((2-methoxybenzylamino)methyl)cyclohexyl)pip...) Show SMILES COc1ccccc1CNCC1(CCCCC1)N1CCN(CC1)C(=O)[C@H]1CN(C[C@@H]1c1ccc(Cl)cc1)C(C)C Show InChI InChI=1S/C33H47ClN4O2/c1-25(2)37-22-29(26-11-13-28(34)14-12-26)30(23-37)32(39)36-17-19-38(20-18-36)33(15-7-4-8-16-33)24-35-21-27-9-5-6-10-31(27)40-3/h5-6,9-14,25,29-30,35H,4,7-8,15-24H2,1-3H3/t29-,30+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225610 ((4-(1-((4-(dimethylamino)benzylamino)methyl)cycloh...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccc(cc2)N(C)C)CCCCC1 Show InChI InChI=1S/C34H50ClN5O/c1-26(2)39-23-31(28-10-12-29(35)13-11-28)32(24-39)33(41)38-18-20-40(21-19-38)34(16-6-5-7-17-34)25-36-22-27-8-14-30(15-9-27)37(3)4/h8-15,26,31-32,36H,5-7,16-25H2,1-4H3/t31-,32+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225612 (((3R,4S)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccoc2)CCCCC1 Show InChI InChI=1S/C30H43ClN4O2/c1-23(2)34-19-27(25-6-8-26(31)9-7-25)28(20-34)29(36)33-13-15-35(16-14-33)30(11-4-3-5-12-30)22-32-18-24-10-17-37-21-24/h6-10,17,21,23,27-28,32H,3-5,11-16,18-20,22H2,1-2H3/t27-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	75	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225595 (((3R,4S)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccccn2)CCCCC1 Show InChI InChI=1S/C31H44ClN5O/c1-24(2)36-21-28(25-9-11-26(32)12-10-25)29(22-36)30(38)35-16-18-37(19-17-35)31(13-5-3-6-14-31)23-33-20-27-8-4-7-15-34-27/h4,7-12,15,24,28-29,33H,3,5-6,13-14,16-23H2,1-2H3/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	76	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225606 ((4-(1-((4-chlorobenzylamino)methyl)cyclohexyl)pipe...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccc(Cl)cc2)CCCCC1 Show InChI InChI=1S/C32H44Cl2N4O/c1-24(2)37-21-29(26-8-12-28(34)13-9-26)30(22-37)31(39)36-16-18-38(19-17-36)32(14-4-3-5-15-32)23-35-20-25-6-10-27(33)11-7-25/h6-13,24,29-30,35H,3-5,14-23H2,1-2H3/t29-,30+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225646 (1-((3R,4S)-3-(1-(1-((benzylamino)methyl)cyclohexyl...) Show SMILES CNCC(=O)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccccc2)CCCCC1 Show InChI InChI=1S/C32H44ClN5O2/c1-34-21-30(39)37-22-28(26-10-12-27(33)13-11-26)29(23-37)31(40)36-16-18-38(19-17-36)32(14-6-3-7-15-32)24-35-20-25-8-4-2-5-9-25/h2,4-5,8-13,28-29,34-35H,3,6-7,14-24H2,1H3/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225639 ((4-(1-((benzylamino)methyl)cyclohexyl)piperazin-1-...) Show SMILES COCC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccccc2)CCCCC1 |w:3.3| Show InChI InChI=1S/C33H47ClN4O2/c1-26(24-40-2)37-22-30(28-11-13-29(34)14-12-28)31(23-37)32(39)36-17-19-38(20-18-36)33(15-7-4-8-16-33)25-35-21-27-9-5-3-6-10-27/h3,5-6,9-14,26,30-31,35H,4,7-8,15-25H2,1-2H3/t26?,30-,31+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225633 (3-amino-1-((3R,4S)-3-(1-(1-((benzylamino)methyl)cy...) Show SMILES NCCC(=O)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccccc2)CCCCC1 Show InChI InChI=1S/C32H44ClN5O2/c33-27-11-9-26(10-12-27)28-22-37(30(39)13-16-34)23-29(28)31(40)36-17-19-38(20-18-36)32(14-5-2-6-15-32)24-35-21-25-7-3-1-4-8-25/h1,3-4,7-12,28-29,35H,2,5-6,13-24,34H2/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225582 ((4-(1-((2-(trifluoromethoxy)benzylamino)methyl)cyc...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccccc2OC(F)(F)F)CCCCC1 Show InChI InChI=1S/C33H44ClF3N4O2/c1-24(2)40-21-28(25-10-12-27(34)13-11-25)29(22-40)31(42)39-16-18-41(19-17-39)32(14-6-3-7-15-32)23-38-20-26-8-4-5-9-30(26)43-33(35,36)37/h4-5,8-13,24,28-29,38H,3,6-7,14-23H2,1-2H3/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225597 ((4-(1-(((4-methoxybenzyl)(methyl)amino)methyl)cycl...) Show SMILES COc1ccc(CN(C)CC2(CCCCC2)N2CCN(CC2)C(=O)[C@H]2CN(C[C@@H]2c2ccc(Cl)cc2)C(C)C)cc1 Show InChI InChI=1S/C34H49ClN4O2/c1-26(2)38-23-31(28-10-12-29(35)13-11-28)32(24-38)33(40)37-18-20-39(21-19-37)34(16-6-5-7-17-34)25-36(3)22-27-8-14-30(41-4)15-9-27/h8-15,26,31-32H,5-7,16-25H2,1-4H3/t31-,32+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225621 (((3R,4S)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2nccs2)CCCCC1 Show InChI InChI=1S/C29H42ClN5OS/c1-22(2)34-19-25(23-6-8-24(30)9-7-23)26(20-34)28(36)33-13-15-35(16-14-33)29(10-4-3-5-11-29)21-31-18-27-32-12-17-37-27/h6-9,12,17,22,25-26,31H,3-5,10-11,13-16,18-21H2,1-2H3/t25-,26+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225640 ((4-(1-((4-(trifluoromethyl)benzylamino)methyl)cycl...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccc(cc2)C(F)(F)F)CCCCC1 Show InChI InChI=1S/C33H44ClF3N4O/c1-24(2)40-21-29(26-8-12-28(34)13-9-26)30(22-40)31(42)39-16-18-41(19-17-39)32(14-4-3-5-15-32)23-38-20-25-6-10-27(11-7-25)33(35,36)37/h6-13,24,29-30,38H,3-5,14-23H2,1-2H3/t29-,30+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225628 ((4-(1-((2-(trifluoromethyl)benzylamino)methyl)cycl...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccccc2C(F)(F)F)CCCCC1 Show InChI InChI=1S/C33H44ClF3N4O/c1-24(2)40-21-28(25-10-12-27(34)13-11-25)29(22-40)31(42)39-16-18-41(19-17-39)32(14-6-3-7-15-32)23-38-20-26-8-4-5-9-30(26)33(35,36)37/h4-5,8-13,24,28-29,38H,3,6-7,14-23H2,1-2H3/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225594 (((3R,4S)-1-benzyl-4-(4-chlorophenyl)pyrrolidin-3-y...) Show SMILES Clc1ccc(cc1)[C@H]1CN(Cc2ccccc2)C[C@@H]1C(=O)N1CCN(CC1)C1(CNCc2ccccc2)CCCCC1 Show InChI InChI=1S/C36H45ClN4O/c37-32-16-14-31(15-17-32)33-26-39(25-30-12-6-2-7-13-30)27-34(33)35(42)40-20-22-41(23-21-40)36(18-8-3-9-19-36)28-38-24-29-10-4-1-5-11-29/h1-2,4-7,10-17,33-34,38H,3,8-9,18-28H2/t33-,34+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225637 (CHEMBL398285 | {4-[1-(benzylamino-methyl)-cyclohex...) Show SMILES Clc1ccc(cc1)[C@H]1CN(C[C@@H]1C(=O)N1CCN(CC1)C1(CNCc2ccccc2)CCCCC1)C(=O)C1CCCC1 Show InChI InChI=1S/C35H47ClN4O2/c36-30-15-13-28(14-16-30)31-24-39(33(41)29-11-5-6-12-29)25-32(31)34(42)38-19-21-40(22-20-38)35(17-7-2-8-18-35)26-37-23-27-9-3-1-4-10-27/h1,3-4,9-10,13-16,29,31-32,37H,2,5-8,11-12,17-26H2/t31-,32+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225622 ((4-(1-(((4-methoxybenzyl)(ethyl)amino)methyl)cyclo...) Show SMILES CCN(Cc1ccc(OC)cc1)CC1(CCCCC1)N1CCN(CC1)C(=O)[C@H]1CN(C[C@@H]1c1ccc(Cl)cc1)C(C)C Show InChI InChI=1S/C35H51ClN4O2/c1-5-37(23-28-9-15-31(42-4)16-10-28)26-35(17-7-6-8-18-35)40-21-19-38(20-22-40)34(41)33-25-39(27(2)3)24-32(33)29-11-13-30(36)14-12-29/h9-16,27,32-33H,5-8,17-26H2,1-4H3/t32-,33+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225636 (1-((3R,4S)-3-(1-(1-((benzylamino)methyl)cyclohexyl...) Show SMILES CC(=O)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccccc2)CCCCC1 Show InChI InChI=1S/C31H41ClN4O2/c1-24(37)35-21-28(26-10-12-27(32)13-11-26)29(22-35)30(38)34-16-18-36(19-17-34)31(14-6-3-7-15-31)23-33-20-25-8-4-2-5-9-25/h2,4-5,8-13,28-29,33H,3,6-7,14-23H2,1H3/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225608 (1-((3R,4S)-3-(1-(1-((benzylamino)methyl)cyclohexyl...) Show SMILES CCCC(=O)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccccc2)CCCCC1 Show InChI InChI=1S/C33H45ClN4O2/c1-2-9-31(39)37-23-29(27-12-14-28(34)15-13-27)30(24-37)32(40)36-18-20-38(21-19-36)33(16-7-4-8-17-33)25-35-22-26-10-5-3-6-11-26/h3,5-6,10-15,29-30,35H,2,4,7-9,16-25H2,1H3/t29-,30+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	190	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225591 (((3R,4S)-1-benzyl-4-(4-chlorophenyl)pyrrolidin-3-y...) Show SMILES Clc1ccc(cc1)[C@H]1CN(Cc2ccccc2)C[C@@H]1C(=O)N1CCN(CC1)C1(CNCc2ccncc2)CCCCC1 Show InChI InChI=1S/C35H44ClN5O/c36-31-11-9-30(10-12-31)32-25-39(24-29-7-3-1-4-8-29)26-33(32)34(42)40-19-21-41(22-20-40)35(15-5-2-6-16-35)27-38-23-28-13-17-37-18-14-28/h1,3-4,7-14,17-18,32-33,38H,2,5-6,15-16,19-27H2/t32-,33+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225600 (1-((3R,4S)-3-(1-(1-((benzylamino)methyl)cyclohexyl...) Show SMILES CC(C)C(=O)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccccc2)CCCCC1 Show InChI InChI=1S/C33H45ClN4O2/c1-25(2)31(39)37-22-29(27-11-13-28(34)14-12-27)30(23-37)32(40)36-17-19-38(20-18-36)33(15-7-4-8-16-33)24-35-21-26-9-5-3-6-10-26/h3,5-6,9-14,25,29-30,35H,4,7-8,15-24H2,1-2H3/t29-,30+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225647 (1-((3R,4S)-3-(1-(1-((benzylamino)methyl)cyclohexyl...) Show SMILES CCC(=O)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2ccccc2)CCCCC1 Show InChI InChI=1S/C32H43ClN4O2/c1-2-30(38)36-22-28(26-11-13-27(33)14-12-26)29(23-36)31(39)35-17-19-37(20-18-35)32(15-7-4-8-16-32)24-34-21-25-9-5-3-6-10-25/h3,5-6,9-14,28-29,34H,2,4,7-8,15-24H2,1H3/t28-,29+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225617 ((4-(1-(((1H-imidazol-4-yl)methylamino)methyl)cyclo...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2cnc[nH]2)CCCCC1 Show InChI InChI=1S/C29H43ClN6O/c1-22(2)35-18-26(23-6-8-24(30)9-7-23)27(19-35)28(37)34-12-14-36(15-13-34)29(10-4-3-5-11-29)20-31-16-25-17-32-21-33-25/h6-9,17,21-22,26-27,31H,3-5,10-16,18-20H2,1-2H3,(H,32,33)/t26-,27+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50225625 (((3R,4S)-4-(4-chlorophenyl)-1-isopropylpyrrolidin-...) Show SMILES CC(C)N1C[C@@H]([C@H](C1)c1ccc(Cl)cc1)C(=O)N1CCN(CC1)C1(CNCc2cncnc2)CCCCC1 Show InChI InChI=1S/C30H43ClN6O/c1-23(2)36-19-27(25-6-8-26(31)9-7-25)28(20-36)29(38)35-12-14-37(15-13-35)30(10-4-3-5-11-30)21-32-16-24-17-33-22-34-18-24/h6-9,17-18,22-23,27-28,32H,3-5,10-16,19-21H2,1-2H3/t27-,28+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [12]NDPMSH from human MC4R expressed in HEK293 cells				Bioorg Med Chem Lett 17: 6825-31 (2007) Article DOI: 10.1016/j.bmcl.2007.10.032 BindingDB Entry DOI: 10.7270/Q2862G5Z
					More data for this Ligand-Target Pair

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