BindingDB PrimarySearch

Found 24 hits Enz. Inhib. hit(s) with all data for entry = 50021667
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Carboxypeptidase B (Sus scrofa)	BDBM50201438 ((+/-)-5-guanidino-2-(mercaptomethyl)pentanoic acid...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of porcine pancreatic carboxypeptidase B				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase N catalytic chain (Homo sapiens (Human))	BDBM50201438 ((+/-)-5-guanidino-2-(mercaptomethyl)pentanoic acid...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human plasma carboxypeptidase N				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50201438 ((+/-)-5-guanidino-2-(mercaptomethyl)pentanoic acid...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226610 ((2S)-5-AMINO-2-[(1-PROPYL-1H-IMIDAZOL-4-YL)METHYL]...) Show SMILES CCCn1cnc(C[C@H](CCCN)C(O)=O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase A1 (Bos taurus (bovine))	BDBM50109593 (2-Benzyl-3-mercapto-propionic acid \| 2-Mercaptomet...) Show SMILES OC(=O)C(CS)Cc1ccccc1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of bovine pancreatic carboxypeptidase A				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226605 ((+/-)-5-amino-2-((1-propyl-1H-imidazol-4-yl)methyl...) Show SMILES CCCn1cnc(CC(CCCN)C(O)=O)c1 \|w:8.8\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226598 ((S)-2-(2-aminoethylamino)-3-(1-butyl-1H-imidazol-4...) Show SMILES CCCCn1cnc(C[C@H](NCCN)C(O)=O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226606 ((S)-2-(2-aminoethylamino)-3-(1-propyl-1H-imidazol-...) Show SMILES CCCn1cnc(C[C@H](NCCN)C(O)=O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	84	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226597 ((S)-2-(2-aminoethylamino)-3-(1-isobutyl-1H-imidazo...) Show SMILES CC(C)Cn1cnc(C[C@H](NCCN)C(O)=O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226611 ((S)-2-(2-aminoethylamino)-3-(1-(3-hydroxypropyl)-1...) Show SMILES NCCN[C@@H](Cc1cn(CCCO)cn1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	111	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226614 ((S)-2-(2-aminoethylamino)-3-(1-(cyclobutylmethyl)-...) Show SMILES NCCN[C@@H](Cc1cn(CC2CCC2)cn1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	124	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226607 ((+/-)-2-((1H-imidazol-4-yl)methyl)-5-aminopentanoi...) Show SMILES NCCCC(Cc1cnc[nH]1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226613 ((S)-2-(2-aminoethylamino)-3-(1-phenethyl-1H-imidaz...) Show SMILES NCCN[C@@H](Cc1cn(CCc2ccccc2)cn1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226602 ((S)-2-(2-aminoethylamino)-3-(1-pentyl-1H-imidazol-...) Show SMILES CCCCCn1cnc(C[C@H](NCCN)C(O)=O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B (Sus scrofa)	BDBM50226610 ((2S)-5-AMINO-2-[(1-PROPYL-1H-IMIDAZOL-4-YL)METHYL]...) Show SMILES CCCn1cnc(C[C@H](CCCN)C(O)=O)c1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	206	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of porcine pancreatic carboxypeptidase B				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226601 ((2S)-2-[(2-aminoethyl)amino]-3-(1-methyl-1H-imidaz...) Show SMILES Cn1cnc(C[C@H](NCCN)C(O)=O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	235	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226599 ((S)-2-(2-aminoethylamino)-3-(1-ethyl-1H-imidazol-4...) Show SMILES CCn1cnc(C[C@H](NCCN)C(O)=O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226608 ((S)-2-(2-aminoethylamino)-3-(1-benzyl-1H-imidazol-...) Show SMILES NCCN[C@@H](Cc1cn(Cc2ccccc2)cn1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	269	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226603 ((+/-)-5-amino-2-(mercaptomethyl)pentanoic acid \| C...) Show SMILES NCCCC(CS)C(O)=O \|w:4.4\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	300	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226600 ((2S)-2-[(2-aminoethyl)amino]-3-(1H-imidazol-4-yl)p...) Show SMILES NCCN[C@@H](Cc1cnc[nH]1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	344	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226609 ((S)-2-(2-aminoethylamino)-3-(1-isopropyl-1H-imidaz...) Show SMILES CC(C)n1cnc(C[C@H](NCCN)C(O)=O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226604 (CHEMBL392205 \| ent-(2S)-5-amino-2-[(1-n-propyl-1H-...) Show SMILES CCCn1cnc(C[C@@H](CCCN)C(O)=O)c1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase N catalytic chain (Homo sapiens (Human))	BDBM50226600 ((2S)-2-[(2-aminoethyl)amino]-3-(1H-imidazol-4-yl)p...) Show SMILES NCCN[C@@H](Cc1cnc[nH]1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human plasma carboxypeptidase N				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair
Carboxypeptidase B2 (Homo sapiens (Human))	BDBM50226612 ((R)-2-(2-aminoethylamino)-3-(1H-imidazol-4-yl)prop...) Show SMILES NCCN[C@H](Cc1cnc[nH]1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Inhibition of human TAFIa				J Med Chem 50: 6095-103 (2007) Article DOI: 10.1021/jm0702433 BindingDB Entry DOI: 10.7270/Q2T153CG
Pfizer Global Research and Development Curated by ChEMBL					More data for this Ligand-Target Pair