Compile Data Set for Download or QSAR

Found 23 hits Enz. Inhib. hit(s) with all data for entry = 50021883   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Coagulation factor X (Homo sapiens (Human))	BDBM50228930 ((E)-2-(6-chloro-benzo[b]thiophen-2-yl)-ethenesulfo...) Show SMILES CS(=O)(=O)c1ccccc1-c1ccc(N2CCC(NS(=O)(=O)\C=C\c3cc4ccc(Cl)cc4s3)C2=O)c(F)c1 |w:17.18| Show InChI InChI=1S/C27H22ClFN2O5S3/c1-38(33,34)26-5-3-2-4-21(26)17-7-9-24(22(29)15-17)31-12-10-23(27(31)32)30-39(35,36)13-11-20-14-18-6-8-19(28)16-25(18)37-20/h2-9,11,13-16,23,30H,10,12H2,1H3/b13-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228950 ((E)-2-(5-chloro-thiophen-2-yl)-ethenesulfonic acid...) Show SMILES CS(=O)(=O)c1ccccc1-c1ccc(N2CCC(NS(=O)(=O)\C=C\c3ccc(Cl)s3)C2=O)c(F)c1 |w:17.18| Show InChI InChI=1S/C23H20ClFN2O5S3/c1-34(29,30)21-5-3-2-4-17(21)15-6-8-20(18(25)14-15)27-12-10-19(23(27)28)26-35(31,32)13-11-16-7-9-22(24)33-16/h2-9,11,13-14,19,26H,10,12H2,1H3/b13-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228954 ((E)-2-(6-(3-(2-(5-chlorothiophen-2-yl)vinylsulfona...) Show SMILES CN(C)S(=O)(=O)c1ccccc1-c1ccc(nc1)N1CCC(NS(=O)(=O)\C=C\c2ccc(Cl)s2)C1=O |w:21.23| Show InChI InChI=1S/C23H23ClN4O5S3/c1-27(2)36(32,33)20-6-4-3-5-18(20)16-7-10-22(25-15-16)28-13-11-19(23(28)29)26-35(30,31)14-12-17-8-9-21(24)34-17/h3-10,12,14-15,19,26H,11,13H2,1-2H3/b14-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228940 (6-chloro-N-(1-(4-(2-cyanopyridin-3-yl)-2-fluorophe...) Show SMILES Fc1cc(ccc1N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O)-c1cccnc1C#N |w:10.11| Show InChI InChI=1S/C26H18ClFN4O3S/c27-19-6-3-17-13-20(7-4-16(17)12-19)36(34,35)31-23-9-11-32(26(23)33)25-8-5-18(14-22(25)28)21-2-1-10-30-24(21)15-29/h1-8,10,12-14,23,31H,9,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228932 (6-chloro-N-(1-(2-fluoro-4-(1-methyl-1H-imidazol-2-...) Show SMILES Cn1ccnc1-c1ccc(N2CCC(NS(=O)(=O)c3ccc4cc(Cl)ccc4c3)C2=O)c(F)c1 |w:13.14| Show InChI InChI=1S/C24H20ClFN4O3S/c1-29-11-9-27-23(29)17-4-7-22(20(26)14-17)30-10-8-21(24(30)31)28-34(32,33)19-6-3-15-12-18(25)5-2-16(15)13-19/h2-7,9,11-14,21,28H,8,10H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228947 (6-chloro-benzofuran-2-sulfonic acid [1-(3-fluoro-2...) Show SMILES CS(=O)(=O)c1ccccc1-c1ccc(N2CCC(NS(=O)(=O)c3cc4ccc(Cl)cc4o3)C2=O)c(F)c1 |w:17.18| Show InChI InChI=1S/C25H20ClFN2O6S2/c1-36(31,32)23-5-3-2-4-18(23)15-7-9-21(19(27)12-15)29-11-10-20(25(29)30)28-37(33,34)24-13-16-6-8-17(26)14-22(16)35-24/h2-9,12-14,20,28H,10-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228935 ((E)-2-(5-chloro-thiophen-2-yl)-ethenesulfonic acid...) Show SMILES Clc1ccc(\C=C\S(=O)(=O)NC2CCN(C2=O)c2ccc(cn2)-c2ccccc2C#N)s1 |w:11.10| Show InChI InChI=1S/C22H17ClN4O3S2/c23-20-7-6-17(31-20)10-12-32(29,30)26-19-9-11-27(22(19)28)21-8-5-16(14-25-21)18-4-2-1-3-15(18)13-24/h1-8,10,12,14,19,26H,9,11H2/b12-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228941 (5-chloro-thieno[3,2-b]pyridine-2-sulfonic acid [1-...) Show SMILES CS(=O)(=O)c1ccccc1-c1ccc(N2CCC(NS(=O)(=O)c3cc4nc(Cl)ccc4s3)C2=O)c(F)c1 |w:17.18| Show InChI InChI=1S/C24H19ClFN3O5S3/c1-36(31,32)21-5-3-2-4-15(21)14-6-7-19(16(26)12-14)29-11-10-17(24(29)30)28-37(33,34)23-13-18-20(35-23)8-9-22(25)27-18/h2-9,12-13,17,28H,10-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228936 (6-chloro-N-(1-(2-fluoro-4-(1H-pyrazol-1-yl)phenyl)...) Show SMILES Fc1cc(ccc1N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O)-n1cccn1 |w:10.11| Show InChI InChI=1S/C23H18ClFN4O3S/c24-17-4-2-16-13-19(6-3-15(16)12-17)33(31,32)27-21-8-11-28(23(21)30)22-7-5-18(14-20(22)25)29-10-1-9-26-29/h1-7,9-10,12-14,21,27H,8,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228949 (6-chloro-N-(1-(2-fluoro-4-(1H-imidazol-1-yl)phenyl...) Show SMILES Fc1cc(ccc1N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O)-n1ccnc1 |w:10.11| Show InChI InChI=1S/C23H18ClFN4O3S/c24-17-3-1-16-12-19(5-2-15(16)11-17)33(31,32)27-21-7-9-29(23(21)30)22-6-4-18(13-20(22)25)28-10-8-26-14-28/h1-6,8,10-14,21,27H,7,9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228946 ((E)-2-(5-chlorothiophen-2-yl)-N-(2-oxo-1-(5-(2-(tr...) Show SMILES FC(F)(F)c1ccccc1-c1ccc(nc1)N1CCC(NS(=O)(=O)\C=C\c2ccc(Cl)s2)C1=O |w:19.21| Show InChI InChI=1S/C22H17ClF3N3O3S2/c23-19-7-6-15(33-19)10-12-34(31,32)28-18-9-11-29(21(18)30)20-8-5-14(13-27-20)16-3-1-2-4-17(16)22(24,25)26/h1-8,10,12-13,18,28H,9,11H2/b12-10+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228953 (5-chloro-benzofuran-2-sulfonic acid [1-(3-fluoro-2...) Show SMILES CS(=O)(=O)c1ccccc1-c1ccc(N2CCC(NS(=O)(=O)c3cc4cc(Cl)ccc4o3)C2=O)c(F)c1 |w:17.18| Show InChI InChI=1S/C25H20ClFN2O6S2/c1-36(31,32)23-5-3-2-4-18(23)15-6-8-21(19(27)13-15)29-11-10-20(25(29)30)28-37(33,34)24-14-16-12-17(26)7-9-22(16)35-24/h2-9,12-14,20,28H,10-11H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228951 (6-chloro-N-(1-(2-fluoro-4-(pyridin-3-yl)phenyl)-2-...) Show SMILES Fc1cc(ccc1N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O)-c1cccnc1 |w:10.11| Show InChI InChI=1S/C25H19ClFN3O3S/c26-20-6-3-17-13-21(7-4-16(17)12-20)34(32,33)29-23-9-11-30(25(23)31)24-8-5-18(14-22(24)27)19-2-1-10-28-15-19/h1-8,10,12-15,23,29H,9,11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228945 (6-chloro-N-(1-(2-fluoro-4-(pyridin-4-yl)phenyl)-2-...) Show SMILES Fc1cc(ccc1N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O)-c1ccncc1 |w:10.11| Show InChI InChI=1S/C25H19ClFN3O3S/c26-20-4-1-18-14-21(5-2-17(18)13-20)34(32,33)29-23-9-12-30(25(23)31)24-6-3-19(15-22(24)27)16-7-10-28-11-8-16/h1-8,10-11,13-15,23,29H,9,12H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228933 ((E)-2-(5-chlorothiophen-2-yl)-N-(1-(5-(2-(N-methyl...) Show SMILES CN(c1ccccc1-c1ccc(nc1)N1CCC(NS(=O)(=O)\C=C\c2ccc(Cl)s2)C1=O)S(C)(=O)=O |w:17.19| Show InChI InChI=1S/C23H23ClN4O5S3/c1-27(35(2,30)31)20-6-4-3-5-18(20)16-7-10-22(25-15-16)28-13-11-19(23(28)29)26-36(32,33)14-12-17-8-9-21(24)34-17/h3-10,12,14-15,19,26H,11,13H2,1-2H3/b14-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228939 ((E)-2-(6-(3-(2-(5-chlorothiophen-2-yl)vinylsulfona...) Show SMILES CN(C)C(=O)c1ccccc1-c1ccc(nc1)N1CCC(NS(=O)(=O)\C=C\c2ccc(Cl)s2)C1=O |w:20.22| Show InChI InChI=1S/C24H23ClN4O4S2/c1-28(2)23(30)19-6-4-3-5-18(19)16-7-10-22(26-15-16)29-13-11-20(24(29)31)27-35(32,33)14-12-17-8-9-21(25)34-17/h3-10,12,14-15,20,27H,11,13H2,1-2H3/b14-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228937 ((E)-2-(5-chloro-thiophen-2-yl)-ethenesulfonic acid...) Show SMILES CS(=O)(=O)Nc1ccccc1-c1ccc(nc1)N1CCC(NS(=O)(=O)\C=C\c2ccc(Cl)s2)C1=O |w:20.22| Show InChI InChI=1S/C22H21ClN4O5S3/c1-34(29,30)25-18-5-3-2-4-17(18)15-6-9-21(24-14-15)27-12-10-19(22(27)28)26-35(31,32)13-11-16-7-8-20(23)33-16/h2-9,11,13-14,19,25-26H,10,12H2,1H3/b13-11+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by chromogenic assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228938 (6-chloro-N-(1-(2-fluoro-4-(1-methyl-1H-imidazol-4-...) Show SMILES Cn1cnc(c1)-c1ccc(N2CCC(NS(=O)(=O)c3ccc4cc(Cl)ccc4c3)C2=O)c(F)c1 |w:13.14| Show InChI InChI=1S/C24H20ClFN4O3S/c1-29-13-22(27-14-29)17-4-7-23(20(26)12-17)30-9-8-21(24(30)31)28-34(32,33)19-6-3-15-10-18(25)5-2-16(15)11-19/h2-7,10-14,21,28H,8-9H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228934 (6-chloro-N-(1-(2-fluoro-4-(furan-3-yl)phenyl)-2-ox...) Show SMILES Fc1cc(ccc1N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O)-c1ccoc1 |w:10.11| Show InChI InChI=1S/C24H18ClFN2O4S/c25-19-4-1-16-12-20(5-2-15(16)11-19)33(30,31)27-22-7-9-28(24(22)29)23-6-3-17(13-21(23)26)18-8-10-32-14-18/h1-6,8,10-14,22,27H,7,9H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	74.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228948 (6-chloro-N-(2-oxo-1-(5-phenylpyridin-2-yl)pyrrolid...) Show SMILES Clc1ccc2cc(ccc2c1)S(=O)(=O)NC1CCN(C1=O)c1ccc(cn1)-c1ccccc1 |w:15.16| Show InChI InChI=1S/C25H20ClN3O3S/c26-21-9-6-19-15-22(10-7-18(19)14-21)33(31,32)28-23-12-13-29(25(23)30)24-11-8-20(16-27-24)17-4-2-1-3-5-17/h1-11,14-16,23,28H,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228929 ((E)-2-(5-chlorothiophen-2-yl)-N-(1-(5-(2-isopropox...) Show SMILES CC(C)Oc1ccccc1-c1ccc(nc1)N1CCC(NS(=O)(=O)\C=C\c2ccc(Cl)s2)C1=O |w:19.21| Show InChI InChI=1S/C24H24ClN3O4S2/c1-16(2)32-21-6-4-3-5-19(21)17-7-10-23(26-15-17)28-13-11-20(24(28)29)27-34(30,31)14-12-18-8-9-22(25)33-18/h3-10,12,14-16,20,27H,11,13H2,1-2H3/b14-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228943 (6-chloro-naphthalene-2-sulfonic acid [1-(3-fluoro-...) Show SMILES Fc1cc(ccc1N1CCC(NS(=O)(=O)c2ccc3cc(Cl)ccc3c2)C1=O)-c1ccccc1 |w:10.11| Show InChI InChI=1S/C26H20ClFN2O3S/c27-21-9-6-19-15-22(10-7-18(19)14-21)34(32,33)29-24-12-13-30(26(24)31)25-11-8-20(16-23(25)28)17-4-2-1-3-5-17/h1-11,14-16,24,29H,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	215	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by fluorescence assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50228942 ((E)-N-(1-(5-(2-tert-butylphenyl)pyridin-2-yl)-2-ox...) Show SMILES CC(C)(C)c1ccccc1-c1ccc(nc1)N1CCC(NS(=O)(=O)\C=C\c2ccc(Cl)s2)C1=O |w:19.21| Show InChI InChI=1S/C25H26ClN3O3S2/c1-25(2,3)20-7-5-4-6-19(20)17-8-11-23(27-16-17)29-14-12-21(24(29)30)28-34(31,32)15-13-18-9-10-22(26)33-18/h4-11,13,15-16,21,28H,12,14H2,1-3H3/b15-13+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.33E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human F10a by chromogenic assay				Bioorg Med Chem Lett 18: 23-7 (2008) Article DOI: 10.1016/j.bmcl.2007.11.023 BindingDB Entry DOI: 10.7270/Q2SX6CZF
					More data for this Ligand-Target Pair