Compile Data Set for Download or QSAR

Found 45 hits Enz. Inhib. hit(s) with all data for entry = 50022360   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50234380 (CHEMBL245876 | quinolin-8-yl 4-methyl-3-(piperidin...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)Oc1cccc2cccnc12 Show InChI InChI=1S/C22H22N2O4S/c1-16-10-11-18(15-20(16)29(26,27)24-13-3-2-4-14-24)22(25)28-19-9-5-7-17-8-6-12-23-21(17)19/h5-12,15H,2-4,13-14H2,1H3	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB1 receptor expressed in HEK cells				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234380 (CHEMBL245876 | quinolin-8-yl 4-methyl-3-(piperidin...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)Oc1cccc2cccnc12 Show InChI InChI=1S/C22H22N2O4S/c1-16-10-11-18(15-20(16)29(26,27)24-13-3-2-4-14-24)22(25)28-19-9-5-7-17-8-6-12-23-21(17)19/h5-12,15H,2-4,13-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Displacement of [3H]CP55940 from human CB2 receptor expressed in HEK cells				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234383 (CHEMBL252859 | N-cyclohexyl-4-methyl-3-(piperidin-...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)NC1CCCCC1 Show InChI InChI=1S/C19H28N2O3S/c1-15-10-11-16(19(22)20-17-8-4-2-5-9-17)14-18(15)25(23,24)21-12-6-3-7-13-21/h10-11,14,17H,2-9,12-13H2,1H3,(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50211843 (2-(2,4-dichlorophenylamino)-4-trifluoromethyl-pyri...) Show SMILES FC(F)(F)c1nc(Nc2ccc(Cl)cc2Cl)ncc1C(=O)NCC1CCOCC1 Show InChI InChI=1S/C18H17Cl2F3N4O2/c19-11-1-2-14(13(20)7-11)26-17-25-9-12(15(27-17)18(21,22)23)16(28)24-8-10-3-5-29-6-4-10/h1-2,7,9-10H,3-6,8H2,(H,24,28)(H,25,26,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	63	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234384 (4-methyl-3-(piperidin-1-ylsulfonyl)-N-(2-(trifluor...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)Nc1ccccc1C(F)(F)F Show InChI InChI=1S/C20H21F3N2O3S/c1-14-9-10-15(13-18(14)29(27,28)25-11-5-2-6-12-25)19(26)24-17-8-4-3-7-16(17)20(21,22)23/h3-4,7-10,13H,2,5-6,11-12H2,1H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234385 (CHEMBL253671 | N-(4-chlorophenyl)-4-methyl-3-(pipe...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)Nc1ccc(Cl)cc1 Show InChI InChI=1S/C19H21ClN2O3S/c1-14-5-6-15(19(23)21-17-9-7-16(20)8-10-17)13-18(14)26(24,25)22-11-3-2-4-12-22/h5-10,13H,2-4,11-12H2,1H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234387 ((4-cyclohexyl-3-(pyrrolidin-1-ylsulfonyl)phenyl)(o...) Show SMILES O=C(N1CCC2CCCCC2C1)c1ccc(C2CCCCC2)c(c1)S(=O)(=O)N1CCCC1 |w:5.4,10.11| Show InChI InChI=1S/C26H38N2O3S/c29-26(27-17-14-20-8-4-5-11-23(20)19-27)22-12-13-24(21-9-2-1-3-10-21)25(18-22)32(30,31)28-15-6-7-16-28/h12-13,18,20-21,23H,1-11,14-17,19H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234388 ((3-(azepan-1-ylsulfonyl)-4-methylphenyl)(octahydro...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCCCC1)C(=O)N1CCC2CCCCC2C1 |w:22.23,27.30| Show InChI InChI=1S/C23H34N2O3S/c1-18-10-11-20(16-22(18)29(27,28)25-13-6-2-3-7-14-25)23(26)24-15-12-19-8-4-5-9-21(19)17-24/h10-11,16,19,21H,2-9,12-15,17H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234386 ((4-methyl-3-(thiomorpholinosulfonyl)phenyl)(octahy...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCSCC1)C(=O)N1CCC2CCCCC2C1 |w:21.22,26.29| Show InChI InChI=1S/C21H30N2O3S2/c1-16-6-7-18(14-20(16)28(25,26)23-10-12-27-13-11-23)21(24)22-9-8-17-4-2-3-5-19(17)15-22/h6-7,14,17,19H,2-5,8-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234390 (4-methyl-N-(1-methylcyclohexyl)-3-(piperidin-1-yls...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)NC1(C)CCCCC1 Show InChI InChI=1S/C20H30N2O3S/c1-16-9-10-17(19(23)21-20(2)11-5-3-6-12-20)15-18(16)26(24,25)22-13-7-4-8-14-22/h9-10,15H,3-8,11-14H2,1-2H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234389 ((4-methyl-3-(piperidin-1-ylsulfonyl)phenyl)(octahy...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)N1CCCC2CCCCC12 |w:22.23,27.28| Show InChI InChI=1S/C22H32N2O3S/c1-17-11-12-19(16-21(17)28(26,27)23-13-5-2-6-14-23)22(25)24-15-7-9-18-8-3-4-10-20(18)24/h11-12,16,18,20H,2-10,13-15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234392 (CHEMBL254531 | N-cyclohexyl-3-(pyrrolidin-1-ylsulf...) Show SMILES O=C(NC1CCCCC1)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C17H24N2O3S/c20-17(18-15-8-2-1-3-9-15)14-7-6-10-16(13-14)23(21,22)19-11-4-5-12-19/h6-7,10,13,15H,1-5,8-9,11-12H2,(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234391 (5-(decahydroisoquinoline-2-carbonyl)-N-isobutyl-2-...) Show SMILES CC(C)CNS(=O)(=O)c1cc(ccc1C)C(=O)N1CCC2CCCCC2C1 |w:20.20,25.27| Show InChI InChI=1S/C21H32N2O3S/c1-15(2)13-22-27(25,26)20-12-18(9-8-16(20)3)21(24)23-11-10-17-6-4-5-7-19(17)14-23/h8-9,12,15,17,19,22H,4-7,10-11,13-14H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234393 (4-methyl-3-(piperidin-1-ylsulfonyl)-N-(quinolin-2-...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)Nc1ccc2ccccc2n1 Show InChI InChI=1S/C22H23N3O3S/c1-16-9-10-18(15-20(16)29(27,28)25-13-5-2-6-14-25)22(26)24-21-12-11-17-7-3-4-8-19(17)23-21/h3-4,7-12,15H,2,5-6,13-14H2,1H3,(H,23,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	195	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234397 ((3-(4-isopropylpiperazin-1-ylsulfonyl)-4-methylphe...) Show SMILES CC(C)N1CCN(CC1)S(=O)(=O)c1cc(ccc1C)C(=O)N1CCC2CCCCC2C1 |w:24.25,29.32| Show InChI InChI=1S/C24H37N3O3S/c1-18(2)25-12-14-27(15-13-25)31(29,30)23-16-21(9-8-19(23)3)24(28)26-11-10-20-6-4-5-7-22(20)17-26/h8-9,16,18,20,22H,4-7,10-15,17H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	588	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234395 ((4-methyl-3-(piperidin-1-ylsulfonyl)phenyl)(octahy...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)N1CCC2CCCCC2C1 |w:21.22,26.29| Show InChI InChI=1S/C22H32N2O3S/c1-17-9-10-19(15-21(17)28(26,27)24-12-5-2-6-13-24)22(25)23-14-11-18-7-3-4-8-20(18)16-23/h9-10,15,18,20H,2-8,11-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1.5	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234396 ((4-methyl-3-(morpholinosulfonyl)phenyl)(octahydroi...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCOCC1)C(=O)N1CCC2CCCCC2C1 |w:21.22,26.29| Show InChI InChI=1S/C21H30N2O4S/c1-16-6-7-18(14-20(16)28(25,26)23-10-12-27-13-11-23)21(24)22-9-8-17-4-2-3-5-19(17)15-22/h6-7,14,17,19H,2-5,8-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234394 ((4-methyl-3-(piperidin-1-ylsulfonyl)phenyl)((trans...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)N1CC[C@@H]2CCCC[C@H]2C1 Show InChI InChI=1S/C22H32N2O3S/c1-17-9-10-19(15-21(17)28(26,27)24-12-5-2-6-13-24)22(25)23-14-11-18-7-3-4-8-20(18)16-23/h9-10,15,18,20H,2-8,11-14,16H2,1H3/t18-,20-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234398 (CHEMBL269477 | N-(2-methoxyphenyl)-4-methyl-3-(pip...) Show SMILES COc1ccccc1NC(=O)c1ccc(C)c(c1)S(=O)(=O)N1CCCCC1 Show InChI InChI=1S/C20H24N2O4S/c1-15-10-11-16(20(23)21-17-8-4-5-9-18(17)26-2)14-19(15)27(24,25)22-12-6-3-7-13-22/h4-5,8-11,14H,3,6-7,12-13H2,1-2H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234402 (4-methyl-N-phenyl-3-(piperidin-1-ylsulfonyl)benzam...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)Nc1ccccc1 Show InChI InChI=1S/C19H22N2O3S/c1-15-10-11-16(19(22)20-17-8-4-2-5-9-17)14-18(15)25(23,24)21-12-6-3-7-13-21/h2,4-5,8-11,14H,3,6-7,12-13H2,1H3,(H,20,22)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	139	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234399 (4-methyl-3-(piperidin-1-ylsulfonyl)-N-(quinolin-8-...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)Nc1cccc2cccnc12 Show InChI InChI=1S/C22H23N3O3S/c1-16-10-11-18(15-20(16)29(27,28)25-13-3-2-4-14-25)22(26)24-19-9-5-7-17-8-6-12-23-21(17)19/h5-12,15H,2-4,13-14H2,1H3,(H,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234405 ((3-(4-hydroxypiperidin-1-ylsulfonyl)-4-methylpheny...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCC(O)CC1)C(=O)N1CCC2CCCCC2C1 |w:22.23,27.30| Show InChI InChI=1S/C22H32N2O4S/c1-16-6-7-18(14-21(16)29(27,28)24-12-9-20(25)10-13-24)22(26)23-11-8-17-4-2-3-5-19(17)15-23/h6-7,14,17,19-20,25H,2-5,8-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	215	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234403 ((S)-N-(1-cyclohexylethyl)-4-methyl-3-(piperidin-1-...) Show SMILES C[C@H](NC(=O)c1ccc(C)c(c1)S(=O)(=O)N1CCCCC1)C1CCCCC1 Show InChI InChI=1S/C21H32N2O3S/c1-16-11-12-19(21(24)22-17(2)18-9-5-3-6-10-18)15-20(16)27(25,26)23-13-7-4-8-14-23/h11-12,15,17-18H,3-10,13-14H2,1-2H3,(H,22,24)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234400 (4-methyl-N-(2-(methylsulfonyl)phenyl)-3-(piperidin...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)Nc1ccccc1S(C)(=O)=O Show InChI InChI=1S/C20H24N2O5S2/c1-15-10-11-16(14-19(15)29(26,27)22-12-6-3-7-13-22)20(23)21-17-8-4-5-9-18(17)28(2,24)25/h4-5,8-11,14H,3,6-7,12-13H2,1-2H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234401 ((3-(azetidin-1-ylsulfonyl)-4-methylphenyl)(octahyd...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCC1)C(=O)N1CCC2CCCCC2C1 |w:19.20,24.27| Show InChI InChI=1S/C20H28N2O3S/c1-15-7-8-17(13-19(15)26(24,25)22-10-4-11-22)20(23)21-12-9-16-5-2-3-6-18(16)14-21/h7-8,13,16,18H,2-6,9-12,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234407 ((4-chloro-3-(pyrrolidin-1-ylsulfonyl)phenyl)(octah...) Show SMILES Clc1ccc(cc1S(=O)(=O)N1CCCC1)C(=O)N1CCC2CCCCC2C1 |w:20.21,25.28| Show InChI InChI=1S/C20H27ClN2O3S/c21-18-8-7-16(13-19(18)27(25,26)23-10-3-4-11-23)20(24)22-12-9-15-5-1-2-6-17(15)14-22/h7-8,13,15,17H,1-6,9-12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234406 (4-chloro-N-cyclohexyl-3-(pyrrolidin-1-ylsulfonyl)b...) Show SMILES Clc1ccc(cc1S(=O)(=O)N1CCCC1)C(=O)NC1CCCCC1 Show InChI InChI=1S/C17H23ClN2O3S/c18-15-9-8-13(17(21)19-14-6-2-1-3-7-14)12-16(15)24(22,23)20-10-4-5-11-20/h8-9,12,14H,1-7,10-11H2,(H,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234404 (CHEMBL254325 | [3-(1,1-dioxo-1lambda-6-thiomorphol...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCS(=O)(=O)CC1)C(=O)N1CCC2CCCCC2C1 |w:23.24,28.31| Show InChI InChI=1S/C21H30N2O5S2/c1-16-6-7-18(21(24)22-9-8-17-4-2-3-5-19(17)15-22)14-20(16)30(27,28)23-10-12-29(25,26)13-11-23/h6-7,14,17,19H,2-5,8-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234408 (CHEMBL253462 | N-(3-chlorophenyl)-4-methyl-3-(pipe...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)Nc1cccc(Cl)c1 Show InChI InChI=1S/C19H21ClN2O3S/c1-14-8-9-15(19(23)21-17-7-5-6-16(20)13-17)12-18(14)26(24,25)22-10-3-2-4-11-22/h5-9,12-13H,2-4,10-11H2,1H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	27	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234410 ((4-chloro-3-(pyrrolidin-1-ylsulfonyl)phenyl)((tran...) Show SMILES Clc1ccc(cc1S(=O)(=O)N1CCCC1)C(=O)N1CC[C@@H]2CCCC[C@H]2C1 Show InChI InChI=1S/C20H27ClN2O3S/c21-18-8-7-16(13-19(18)27(25,26)23-10-3-4-11-23)20(24)22-12-9-15-5-1-2-6-17(15)14-22/h7-8,13,15,17H,1-6,9-12,14H2/t15-,17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234409 ((4-methyl-3-(piperidin-1-ylsulfonyl)phenyl)(piperi...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)N1CCCCC1 Show InChI InChI=1S/C18H26N2O3S/c1-15-8-9-16(18(21)19-10-4-2-5-11-19)14-17(15)24(22,23)20-12-6-3-7-13-20/h8-9,14H,2-7,10-13H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	82	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234413 (5-(decahydroisoquinoline-2-carbonyl)-N-isopropyl-2...) Show SMILES CC(C)NS(=O)(=O)c1cc(ccc1C)C(=O)N1CCC2CCCCC2C1 |w:19.19,24.26| Show InChI InChI=1S/C20H30N2O3S/c1-14(2)21-26(24,25)19-12-17(9-8-15(19)3)20(23)22-11-10-16-6-4-5-7-18(16)13-22/h8-9,12,14,16,18,21H,4-7,10-11,13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.28E+3	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234412 ((4-isopropyl-3-(pyrrolidin-1-ylsulfonyl)phenyl)(oc...) Show SMILES CC(C)c1ccc(cc1S(=O)(=O)N1CCCC1)C(=O)N1CCC2CCCCC2C1 |w:22.23,27.30| Show InChI InChI=1S/C23H34N2O3S/c1-17(2)21-10-9-19(15-22(21)29(27,28)25-12-5-6-13-25)23(26)24-14-11-18-7-3-4-8-20(18)16-24/h9-10,15,17-18,20H,3-8,11-14,16H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	0.400	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234415 (CHEMBL253461 | N-(2-chlorophenyl)-N,4-dimethyl-3-(...) Show SMILES CN(C(=O)c1ccc(C)c(c1)S(=O)(=O)N1CCCCC1)c1ccccc1Cl Show InChI InChI=1S/C20H23ClN2O3S/c1-15-10-11-16(20(24)22(2)18-9-5-4-8-17(18)21)14-19(15)27(25,26)23-12-6-3-7-13-23/h4-5,8-11,14H,3,6-7,12-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234414 (CHEMBL402768 | N-(2-chlorophenyl)-4-methyl-3-(pipe...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)Nc1ccccc1Cl Show InChI InChI=1S/C19H21ClN2O3S/c1-14-9-10-15(19(23)21-17-8-4-3-7-16(17)20)13-18(14)26(24,25)22-11-5-2-6-12-22/h3-4,7-10,13H,2,5-6,11-12H2,1H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234419 (((trans)-octahydroisoquinolin-2(1H)-yl)(3-(pyrroli...) Show SMILES O=C(N1CC[C@@H]2CCCC[C@H]2C1)c1cccc(c1)S(=O)(=O)N1CCCC1 Show InChI InChI=1S/C20H28N2O3S/c23-20(21-13-10-16-6-1-2-7-18(16)15-21)17-8-5-9-19(14-17)26(24,25)22-11-3-4-12-22/h5,8-9,14,16,18H,1-4,6-7,10-13,15H2/t16-,18-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234417 (CHEMBL254730 | N-cyclohexyl-4-isopropyl-3-(pyrroli...) Show SMILES CC(C)c1ccc(cc1S(=O)(=O)N1CCCC1)C(=O)NC1CCCCC1 Show InChI InChI=1S/C20H30N2O3S/c1-15(2)18-11-10-16(20(23)21-17-8-4-3-5-9-17)14-19(18)26(24,25)22-12-6-7-13-22/h10-11,14-15,17H,3-9,12-13H2,1-2H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234418 ((2,3-Dichloro-phenyl)-[5-methoxy-2-methyl-3-(2-mor...) Show SMILES COc1ccc2n(C(=O)c3cccc(Cl)c3Cl)c(C)c(CCN3CCOCC3)c2c1 Show InChI InChI=1S/C23H24Cl2N2O3/c1-15-17(8-9-26-10-12-30-13-11-26)19-14-16(29-2)6-7-21(19)27(15)23(28)18-4-3-5-20(24)22(18)25/h3-7,14H,8-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	n/a	0.650	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234411 ((R)-N-(1-cyclohexylethyl)-4-methyl-3-(piperidin-1-...) Show SMILES C[C@@H](NC(=O)c1ccc(C)c(c1)S(=O)(=O)N1CCCCC1)C1CCCCC1 Show InChI InChI=1S/C21H32N2O3S/c1-16-11-12-19(21(24)22-17(2)18-9-5-3-6-10-18)15-20(16)27(25,26)23-13-7-4-8-14-23/h11-12,15,17-18H,3-10,13-14H2,1-2H3,(H,22,24)/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234416 (CHEMBL439248 | N-(isoquinolin-1-yl)-4-methyl-3-(pi...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCCC1)C(=O)Nc1nccc2ccccc12 Show InChI InChI=1S/C22H23N3O3S/c1-16-9-10-18(15-20(16)29(27,28)25-13-5-2-6-14-25)22(26)24-21-19-8-4-3-7-17(19)11-12-23-21/h3-4,7-12,15H,2,5-6,13-14H2,1H3,(H,23,24,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	1	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234421 (CHEMBL253056 | N-cyclohexyl-N,4-dimethyl-3-(piperi...) Show SMILES CN(C1CCCCC1)C(=O)c1ccc(C)c(c1)S(=O)(=O)N1CCCCC1 Show InChI InChI=1S/C20H30N2O3S/c1-16-11-12-17(20(23)21(2)18-9-5-3-6-10-18)15-19(16)26(24,25)22-13-7-4-8-14-22/h11-12,15,18H,3-10,13-14H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	119	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234422 ((4-methyl-3-(pyrrolidin-1-ylsulfonyl)phenyl)(octah...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCC1)C(=O)N1CCC2CCCCC2C1 |w:20.21,25.28| Show InChI InChI=1S/C21H30N2O3S/c1-16-8-9-18(14-20(16)27(25,26)23-11-4-5-12-23)21(24)22-13-10-17-6-2-3-7-19(17)15-22/h8-9,14,17,19H,2-7,10-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234420 (5-(decahydroisoquinoline-2-carbonyl)-2-methyl-N-ph...) Show SMILES Cc1ccc(cc1S(=O)(=O)Nc1ccccc1)C(=O)N1CCC2CCCCC2C1 |w:22.23,27.30| Show InChI InChI=1S/C23H28N2O3S/c1-17-11-12-19(15-22(17)29(27,28)24-21-9-3-2-4-10-21)23(26)25-14-13-18-7-5-6-8-20(18)16-25/h2-4,9-12,15,18,20,24H,5-8,13-14,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234381 (CHEMBL254530 | N-cyclohexyl-4-methyl-3-(pyrrolidin...) Show SMILES Cc1ccc(cc1S(=O)(=O)N1CCCC1)C(=O)NC1CCCCC1 Show InChI InChI=1S/C18H26N2O3S/c1-14-9-10-15(18(21)19-16-7-3-2-4-8-16)13-17(14)24(22,23)20-11-5-6-12-20/h9-10,13,16H,2-8,11-12H2,1H3,(H,19,21)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM50234382 (4-methyl-3-(piperidin-1-ylsulfonyl)-N-o-tolylbenza...) Show SMILES Cc1ccccc1NC(=O)c1ccc(C)c(c1)S(=O)(=O)N1CCCCC1 Show InChI InChI=1S/C20H24N2O3S/c1-15-8-4-5-9-18(15)21-20(23)17-11-10-16(2)19(14-17)26(24,25)22-12-6-3-7-13-22/h4-5,8-11,14H,3,6-7,12-13H2,1-2H3,(H,21,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	154	n/a	n/a	n/a	n/a
Evotec (UK) Ltd. Curated by ChEMBL					Assay Description Agonist activity at human CB2 receptor expressed in CHO cells assessed as inhibition of forskolin-stimulated cAMP level				Bioorg Med Chem Lett 18: 1725-9 (2008) Article DOI: 10.1016/j.bmcl.2008.01.042 BindingDB Entry DOI: 10.7270/Q2X92B1F
					More data for this Ligand-Target Pair