BindingDB PrimarySearch

Found 12 hits Enz. Inhib. hit(s) with all data for entry = 50026245
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50244177 (1'-[(3-methyl-1-phenyl-1H-pyrazol-4-yl)methyl]-3H-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG in HEK293 cell membrane				Bioorg Med Chem Lett 18: 3778-82 (2008) Article DOI: 10.1016/j.bmcl.2008.05.036 BindingDB Entry DOI: 10.7270/Q2XD11G6
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50244177 (1'-[(3-methyl-1-phenyl-1H-pyrazol-4-yl)methyl]-3H-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphin from human cloned mu opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 3778-82 (2008) Article DOI: 10.1016/j.bmcl.2008.05.036 BindingDB Entry DOI: 10.7270/Q2XD11G6
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50244275 (1'-{[3-methyl-1-(3-methylpyridin-2-yl)-1H-pyrazol-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphin from human cloned mu opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 3778-82 (2008) Article DOI: 10.1016/j.bmcl.2008.05.036 BindingDB Entry DOI: 10.7270/Q2XD11G6
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50244247 (1'-{[1-(3-chloropyridin-2-yl)-3-methyl-1H-pyrazol-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphin from human cloned mu opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 3778-82 (2008) Article DOI: 10.1016/j.bmcl.2008.05.036 BindingDB Entry DOI: 10.7270/Q2XD11G6
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50244247 (1'-{[1-(3-chloropyridin-2-yl)-3-methyl-1H-pyrazol-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG in HEK293 cell membrane				Bioorg Med Chem Lett 18: 3778-82 (2008) Article DOI: 10.1016/j.bmcl.2008.05.036 BindingDB Entry DOI: 10.7270/Q2XD11G6
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50244177 (1'-[(3-methyl-1-phenyl-1H-pyrazol-4-yl)methyl]-3H-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	9.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from human cloned kappa opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 3778-82 (2008) Article DOI: 10.1016/j.bmcl.2008.05.036 BindingDB Entry DOI: 10.7270/Q2XD11G6
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50244247 (1'-{[1-(3-chloropyridin-2-yl)-3-methyl-1H-pyrazol-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from human cloned kappa opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 3778-82 (2008) Article DOI: 10.1016/j.bmcl.2008.05.036 BindingDB Entry DOI: 10.7270/Q2XD11G6
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50244313 (1'-{[1-(3-chloropyridin-2-yl)-1H-pyrazol-4-yl]meth...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]diprenorphin from human cloned mu opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 3778-82 (2008) Article DOI: 10.1016/j.bmcl.2008.05.036 BindingDB Entry DOI: 10.7270/Q2XD11G6
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50244313 (1'-{[1-(3-chloropyridin-2-yl)-1H-pyrazol-4-yl]meth...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from human cloned kappa opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 3778-82 (2008) Article DOI: 10.1016/j.bmcl.2008.05.036 BindingDB Entry DOI: 10.7270/Q2XD11G6
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50244275 (1'-{[3-methyl-1-(3-methylpyridin-2-yl)-1H-pyrazol-...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [3H]U69593 from human cloned kappa opioid receptor expressed in CHO cells				Bioorg Med Chem Lett 18: 3778-82 (2008) Article DOI: 10.1016/j.bmcl.2008.05.036 BindingDB Entry DOI: 10.7270/Q2XD11G6
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50244275 (1'-{[3-methyl-1-(3-methylpyridin-2-yl)-1H-pyrazol-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG in HEK293 cell membrane				Bioorg Med Chem Lett 18: 3778-82 (2008) Article DOI: 10.1016/j.bmcl.2008.05.036 BindingDB Entry DOI: 10.7270/Q2XD11G6
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50244313 (1'-{[1-(3-chloropyridin-2-yl)-1H-pyrazol-4-yl]meth...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Tsukuba Research Institute Curated by ChEMBL					Assay Description Displacement of [35S]MK499 from human ERG in HEK293 cell membrane				Bioorg Med Chem Lett 18: 3778-82 (2008) Article DOI: 10.1016/j.bmcl.2008.05.036 BindingDB Entry DOI: 10.7270/Q2XD11G6
Tsukuba Research Institute Curated by ChEMBL					More data for this Ligand-Target Pair