Compile Data Set for Download or QSAR

Found 68 hits Enz. Inhib. hit(s) with all data for entry = 50026587   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263219 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES CN(C)C(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N Show InChI InChI=1S/C22H19N5OS/c1-13-16-8-9-24-19(16)6-5-18(13)26-21-14(11-23)12-25-22-17(21)10-15(29-22)4-7-20(28)27(2)3/h4-10,12,24H,1-3H3,(H,25,26)/b7-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263265 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES CCN(CC)C(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N Show InChI InChI=1S/C24H23N5OS/c1-4-29(5-2)22(30)9-6-17-12-19-23(16(13-25)14-27-24(19)31-17)28-20-7-8-21-18(15(20)3)10-11-26-21/h6-12,14,26H,4-5H2,1-3H3,(H,27,28)/b9-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50262606 (3-methyl-4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-...) Show SMILES Cc1c(\C=C\C(=O)N2CCCC2)sc2ncc(C#N)c(Nc3ccc4[nH]ccc4c3C)c12 Show InChI InChI=1S/C25H23N5OS/c1-15-18-9-10-27-20(18)6-5-19(15)29-24-17(13-26)14-28-25-23(24)16(2)21(32-25)7-8-22(31)30-11-3-4-12-30/h5-10,14,27H,3-4,11-12H2,1-2H3,(H,28,29)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263132 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrol...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)N4CCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H21N5OS/c1-15-18-8-9-26-21(18)6-5-20(15)28-23-16(13-25)14-27-24-19(23)12-17(31-24)4-7-22(30)29-10-2-3-11-29/h4-9,12,14,26H,2-3,10-11H2,1H3,(H,27,28)/b7-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263218 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(N)=O)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C20H15N5OS/c1-11-14-6-7-23-17(14)4-3-16(11)25-19-12(9-21)10-24-20-15(19)8-13(27-20)2-5-18(22)26/h2-8,10,23H,1H3,(H2,22,26)(H,24,25)/b5-2+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263266 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES CCNC(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N Show InChI InChI=1S/C22H19N5OS/c1-3-24-20(28)7-4-15-10-17-21(14(11-23)12-26-22(17)29-15)27-18-5-6-19-16(13(18)2)8-9-25-19/h4-10,12,25H,3H2,1-2H3,(H,24,28)(H,26,27)/b7-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50262605 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-(pyrrolidin-1...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\CN4CCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H23N5S/c1-16-19-8-9-26-22(19)7-6-21(16)28-23-17(14-25)15-27-24-20(23)13-18(30-24)5-4-12-29-10-2-3-11-29/h4-9,13,15,26H,2-3,10-12H2,1H3,(H,27,28)/b5-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Fyn (Homo sapiens (Human))	BDBM50263132 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrol...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)N4CCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H21N5OS/c1-15-18-8-9-26-21(18)6-5-20(15)28-23-16(13-25)14-27-24-19(23)12-17(31-24)4-7-22(30)29-10-2-3-11-29/h4-9,12,14,26H,2-3,10-11H2,1H3,(H,27,28)/b7-4+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of FYN				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Tyrosine-protein kinase HCK (Homo sapiens (Human))	BDBM50263132 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrol...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)N4CCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H21N5OS/c1-15-18-8-9-26-21(18)6-5-20(15)28-23-16(13-25)14-27-24-19(23)12-17(31-24)4-7-22(30)29-10-2-3-11-29/h4-9,12,14,26H,2-3,10-11H2,1H3,(H,27,28)/b7-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of HCK				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lyn (Homo sapiens (Human))	BDBM50263132 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrol...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)N4CCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H21N5OS/c1-15-18-8-9-26-21(18)6-5-20(15)28-23-16(13-25)14-27-24-19(23)12-17(31-24)4-7-22(30)29-10-2-3-11-29/h4-9,12,14,26H,2-3,10-11H2,1H3,(H,27,28)/b7-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of LYN				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263133 (2-(3-(3-hydroxypyrrolidin-1-yl)-3-oxoprop-1-enyl)-...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)N4CCC(O)C4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H21N5O2S/c1-14-18-6-8-26-21(18)4-3-20(14)28-23-15(11-25)12-27-24-19(23)10-17(32-24)2-5-22(31)29-9-7-16(30)13-29/h2-6,8,10,12,16,26,30H,7,9,13H2,1H3,(H,27,28)/b5-2+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263217 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-(4-methylpipe...) Show SMILES CN1CCN(CC1)C(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N Show InChI InChI=1S/C25H24N6OS/c1-16-19-7-8-27-22(19)5-4-21(16)29-24-17(14-26)15-28-25-20(24)13-18(33-25)3-6-23(32)31-11-9-30(2)10-12-31/h3-8,13,15,27H,9-12H2,1-2H3,(H,28,29)/b6-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50263132 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrol...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)N4CCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H21N5OS/c1-15-18-8-9-26-21(18)6-5-20(15)28-23-16(13-25)14-27-24-19(23)12-17(31-24)4-7-22(30)29-10-2-3-11-29/h4-9,12,14,26H,2-3,10-11H2,1H3,(H,27,28)/b7-4+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of LCK				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263268 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES COCCNC(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N Show InChI InChI=1S/C23H21N5O2S/c1-14-17-7-8-25-20(17)5-4-19(14)28-22-15(12-24)13-27-23-18(22)11-16(31-23)3-6-21(29)26-9-10-30-2/h3-8,11,13,25H,9-10H2,1-2H3,(H,26,29)(H,27,28)/b6-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263175 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(piperi...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)N4CCCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C25H23N5OS/c1-16-19-9-10-27-22(19)7-6-21(16)29-24-17(14-26)15-28-25-20(24)13-18(32-25)5-8-23(31)30-11-3-2-4-12-30/h5-10,13,15,27H,2-4,11-12H2,1H3,(H,28,29)/b8-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263176 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-morpholino-3-...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)N4CCOCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H21N5O2S/c1-15-18-6-7-26-21(18)4-3-20(15)28-23-16(13-25)14-27-24-19(23)12-17(32-24)2-5-22(30)29-8-10-31-11-9-29/h2-7,12,14,26H,8-11H2,1H3,(H,27,28)/b5-2+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50262604 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-(pyrrolidine-...) Show SMILES Cc1c(Nc2c(cnc3sc(cc23)-c2cccc(c2)C(=O)N2CCCC2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C28H23N5OS/c1-17-21-9-10-30-24(21)8-7-23(17)32-26-20(15-29)16-31-27-22(26)14-25(35-27)18-5-4-6-19(13-18)28(34)33-11-2-3-12-33/h4-10,13-14,16,30H,2-3,11-12H2,1H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263218 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(N)=O)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C20H15N5OS/c1-11-14-6-7-23-17(14)4-3-16(11)25-19-12(9-21)10-24-20-15(19)8-13(27-20)2-5-18(22)26/h2-8,10,23H,1H3,(H2,22,26)(H,24,25)/b5-2+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263217 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-(4-methylpipe...) Show SMILES CN1CCN(CC1)C(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N Show InChI InChI=1S/C25H24N6OS/c1-16-19-7-8-27-22(19)5-4-21(16)29-24-17(14-26)15-28-25-20(24)13-18(33-25)3-6-23(32)31-11-9-30(2)10-12-31/h3-8,13,15,27H,9-12H2,1-2H3,(H,28,29)/b6-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263216 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pipera...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)N4CCNCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H22N6OS/c1-15-18-6-7-27-21(18)4-3-20(15)29-23-16(13-25)14-28-24-19(23)12-17(32-24)2-5-22(31)30-10-8-26-9-11-30/h2-7,12,14,26-27H,8-11H2,1H3,(H,28,29)/b5-2+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263301 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES CN(C)NC(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N Show InChI InChI=1S/C22H20N6OS/c1-13-16-8-9-24-19(16)6-5-18(13)26-21-14(11-23)12-25-22-17(21)10-15(30-22)4-7-20(29)27-28(2)3/h4-10,12,24H,1-3H3,(H,25,26)(H,27,29)/b7-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50262605 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-(pyrrolidin-1...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\CN4CCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H23N5S/c1-16-19-8-9-26-22(19)7-6-21(16)28-23-17(14-25)15-27-24-20(23)13-18(30-24)5-4-12-29-10-2-3-11-29/h4-9,13,15,26H,2-3,10-12H2,1H3,(H,27,28)/b5-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263267 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)Nc4ccccc4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C26H19N5OS/c1-16-20-11-12-28-23(20)9-8-22(16)31-25-17(14-27)15-29-26-21(25)13-19(33-26)7-10-24(32)30-18-5-3-2-4-6-18/h2-13,15,28H,1H3,(H,29,31)(H,30,32)/b10-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50262607 (4-(1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrolidin-1-yl...) Show SMILES O=C(\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3)c(cnc2s1)C#N)N1CCCC1 Show InChI InChI=1S/C23H19N5OS/c24-13-16-14-26-23-19(12-18(30-23)4-6-21(29)28-9-1-2-10-28)22(16)27-17-3-5-20-15(11-17)7-8-25-20/h3-8,11-12,14,25H,1-2,9-10H2,(H,26,27)/b6-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263300 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES CN(C)CCN(C)C(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N Show InChI InChI=1S/C25H26N6OS/c1-16-19-9-10-27-22(19)7-6-21(16)29-24-17(14-26)15-28-25-20(24)13-18(33-25)5-8-23(32)31(4)12-11-30(2)3/h5-10,13,15,27H,11-12H2,1-4H3,(H,28,29)/b8-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263174 ((S)-2-(3-(3-(dimethylamino)pyrrolidin-1-yl)-3-oxop...) Show SMILES CN(C)[C@H]1CCN(C1)C(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N |r| Show InChI InChI=1S/C26H26N6OS/c1-16-20-8-10-28-23(20)6-5-22(16)30-25-17(13-27)14-29-26-21(25)12-19(34-26)4-7-24(33)32-11-9-18(15-32)31(2)3/h4-8,10,12,14,18,28H,9,11,15H2,1-3H3,(H,29,30)/b7-4+/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263173 ((R)-2-(3-(3-(dimethylamino)pyrrolidin-1-yl)-3-oxop...) Show SMILES CN(C)[C@@H]1CCN(C1)C(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N |r| Show InChI InChI=1S/C26H26N6OS/c1-16-20-8-10-28-23(20)6-5-22(16)30-25-17(13-27)14-29-26-21(25)12-19(34-26)4-7-24(33)32-11-9-18(15-32)31(2)3/h4-8,10,12,14,18,28H,9,11,15H2,1-3H3,(H,29,30)/b7-4+/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50262604 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-(pyrrolidine-...) Show SMILES Cc1c(Nc2c(cnc3sc(cc23)-c2cccc(c2)C(=O)N2CCCC2)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C28H23N5OS/c1-17-21-9-10-30-24(21)8-7-23(17)32-26-20(15-29)16-31-27-22(26)14-25(35-27)18-5-4-6-19(13-18)28(34)33-11-2-3-12-33/h4-10,13-14,16,30H,2-3,11-12H2,1H3,(H,31,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	180	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263216 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pipera...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)N4CCNCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H22N6OS/c1-15-18-6-7-27-21(18)4-3-20(15)29-23-16(13-25)14-28-24-19(23)12-17(32-24)2-5-22(31)30-10-8-26-9-11-30/h2-7,12,14,26-27H,8-11H2,1H3,(H,28,29)/b5-2+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263265 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES CCN(CC)C(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N Show InChI InChI=1S/C24H23N5OS/c1-4-29(5-2)22(30)9-6-17-12-19-23(16(13-25)14-27-24(19)31-17)28-20-7-8-21-18(15(20)3)10-11-26-21/h6-12,14,26H,4-5H2,1-3H3,(H,27,28)/b9-6+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263303 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrol...) Show SMILES Cc1c(Nc2c(cnc3sc(CCC(=O)N4CCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H23N5OS/c1-15-18-8-9-26-21(18)6-5-20(15)28-23-16(13-25)14-27-24-19(23)12-17(31-24)4-7-22(30)29-10-2-3-11-29/h5-6,8-9,12,14,26H,2-4,7,10-11H2,1H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	250	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Proto-oncogene tyrosine-protein kinase Src (Homo sapiens (Human))	BDBM50263132 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrol...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)N4CCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H21N5OS/c1-15-18-8-9-26-21(18)6-5-20(15)28-23-16(13-25)14-27-24-19(23)12-17(31-24)4-7-22(30)29-10-2-3-11-29/h4-9,12,14,26H,2-3,10-11H2,1H3,(H,27,28)/b7-4+	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of SRC				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263302 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)NN4CCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H22N6OS/c1-15-18-8-9-26-21(18)6-5-20(15)28-23-16(13-25)14-27-24-19(23)12-17(32-24)4-7-22(31)29-30-10-2-3-11-30/h4-9,12,14,26H,2-3,10-11H2,1H3,(H,27,28)(H,29,31)/b7-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263174 ((S)-2-(3-(3-(dimethylamino)pyrrolidin-1-yl)-3-oxop...) Show SMILES CN(C)[C@H]1CCN(C1)C(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N |r| Show InChI InChI=1S/C26H26N6OS/c1-16-20-8-10-28-23(20)6-5-22(16)30-25-17(13-27)14-29-26-21(25)12-19(34-26)4-7-24(33)32-11-9-18(15-32)31(2)3/h4-8,10,12,14,18,28H,9,11,15H2,1-3H3,(H,29,30)/b7-4+/t18-/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	340	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C theta type (Homo sapiens (Human))	BDBM50263302 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)NN4CCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H22N6OS/c1-15-18-8-9-26-21(18)6-5-20(15)28-23-16(13-25)14-27-24-19(23)12-17(32-24)4-7-22(31)29-30-10-2-3-11-30/h4-9,12,14,26H,2-3,10-11H2,1H3,(H,27,28)(H,29,31)/b7-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	370	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCtheta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50262606 (3-methyl-4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-...) Show SMILES Cc1c(\C=C\C(=O)N2CCCC2)sc2ncc(C#N)c(Nc3ccc4[nH]ccc4c3C)c12 Show InChI InChI=1S/C25H23N5OS/c1-15-18-9-10-27-20(18)6-5-19(15)29-24-17(13-26)14-28-25-23(24)16(2)21(32-25)7-8-22(31)30-11-3-4-12-30/h5-10,14,27H,3-4,11-12H2,1-2H3,(H,28,29)/b8-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263301 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES CN(C)NC(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N Show InChI InChI=1S/C22H20N6OS/c1-13-16-8-9-24-19(16)6-5-18(13)26-21-14(11-23)12-25-22-17(21)10-15(30-22)4-7-20(29)27-28(2)3/h4-10,12,24H,1-3H3,(H,25,26)(H,27,29)/b7-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263173 ((R)-2-(3-(3-(dimethylamino)pyrrolidin-1-yl)-3-oxop...) Show SMILES CN(C)[C@@H]1CCN(C1)C(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N |r| Show InChI InChI=1S/C26H26N6OS/c1-16-20-8-10-28-23(20)6-5-22(16)30-25-17(13-27)14-29-26-21(25)12-19(34-26)4-7-24(33)32-11-9-18(15-32)31(2)3/h4-8,10,12,14,18,28H,9,11,15H2,1-3H3,(H,29,30)/b7-4+/t18-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	430	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263175 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(piperi...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)N4CCCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C25H23N5OS/c1-16-19-9-10-27-22(19)7-6-21(16)29-24-17(14-26)15-28-25-20(24)13-18(32-25)5-8-23(31)30-11-3-2-4-12-30/h5-10,13,15,27H,2-4,11-12H2,1H3,(H,28,29)/b8-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263133 (2-(3-(3-hydroxypyrrolidin-1-yl)-3-oxoprop-1-enyl)-...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)N4CCC(O)C4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H21N5O2S/c1-14-18-6-8-26-21(18)4-3-20(14)28-23-15(11-25)12-27-24-19(23)10-17(32-24)2-5-22(31)29-9-7-16(30)13-29/h2-6,8,10,12,16,26,30H,7,9,13H2,1H3,(H,27,28)/b5-2+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	450	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263266 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES CCNC(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N Show InChI InChI=1S/C22H19N5OS/c1-3-24-20(28)7-4-15-10-17-21(14(11-23)12-26-22(17)29-15)27-18-5-6-19-16(13(18)2)8-9-25-19/h4-10,12,25H,3H2,1-2H3,(H,24,28)(H,26,27)/b7-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263267 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)Nc4ccccc4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C26H19N5OS/c1-16-20-11-12-28-23(20)9-8-22(16)31-25-17(14-27)15-29-26-21(25)13-19(33-26)7-10-24(32)30-18-5-3-2-4-6-18/h2-13,15,28H,1H3,(H,29,31)(H,30,32)/b10-7+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263300 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES CN(C)CCN(C)C(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N Show InChI InChI=1S/C25H26N6OS/c1-16-19-9-10-27-22(19)7-6-21(16)29-24-17(14-26)15-28-25-20(24)13-18(33-25)5-8-23(32)31(4)12-11-30(2)3/h5-10,13,15,27H,11-12H2,1-4H3,(H,28,29)/b8-5+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263132 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrol...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)N4CCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H21N5OS/c1-15-18-8-9-26-21(18)6-5-20(15)28-23-16(13-25)14-27-24-19(23)12-17(31-24)4-7-22(30)29-10-2-3-11-29/h4-9,12,14,26H,2-3,10-11H2,1H3,(H,27,28)/b7-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263268 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES COCCNC(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N Show InChI InChI=1S/C23H21N5O2S/c1-14-17-7-8-25-20(17)5-4-19(14)28-22-15(12-24)13-27-23-18(22)11-16(31-23)3-6-21(29)26-9-10-30-2/h3-8,11,13,25H,9-10H2,1-2H3,(H,26,29)(H,27,28)/b6-3+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263303 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrol...) Show SMILES Cc1c(Nc2c(cnc3sc(CCC(=O)N4CCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H23N5OS/c1-15-18-8-9-26-21(18)6-5-20(15)28-23-16(13-25)14-27-24-19(23)12-17(31-24)4-7-22(30)29-10-2-3-11-29/h5-6,8-9,12,14,26H,2-4,7,10-11H2,1H3,(H,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263219 (3-(5-cyano-4-(4-methyl-1H-indol-5-ylamino)thieno[2...) Show SMILES CN(C)C(=O)\C=C\c1cc2c(Nc3ccc4[nH]ccc4c3C)c(cnc2s1)C#N Show InChI InChI=1S/C22H19N5OS/c1-13-16-8-9-24-19(16)6-5-18(13)26-21-14(11-23)12-25-22-17(21)10-15(29-22)4-7-20(28)27(2)3/h4-10,12,24H,1-3H3,(H,25,26)/b7-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C epsilon type (Homo sapiens (Human))	BDBM50263132 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrol...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)N4CCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H21N5OS/c1-15-18-8-9-26-21(18)6-5-20(15)28-23-16(13-25)14-27-24-19(23)12-17(31-24)4-7-22(30)29-10-2-3-11-29/h4-9,12,14,26H,2-3,10-11H2,1H3,(H,27,28)/b7-4+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCepsilon				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Protein kinase C delta type (Homo sapiens (Human))	BDBM50263176 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-morpholino-3-...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)N4CCOCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H21N5O2S/c1-15-18-6-7-26-21(18)4-3-20(15)28-23-16(13-25)14-27-24-19(23)12-17(32-24)2-5-22(30)29-8-10-31-11-9-29/h2-7,12,14,26H,8-11H2,1H3,(H,27,28)/b5-2+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of PKCdelta				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM50263132 (4-(4-methyl-1H-indol-5-ylamino)-2-(3-oxo-3-(pyrrol...) Show SMILES Cc1c(Nc2c(cnc3sc(\C=C\C(=O)N4CCCC4)cc23)C#N)ccc2[nH]ccc12 Show InChI InChI=1S/C24H21N5OS/c1-15-18-8-9-26-21(18)6-5-20(15)28-23-16(13-25)14-27-24-19(23)12-17(31-24)4-7-22(30)29-10-2-3-11-29/h4-9,12,14,26H,2-3,10-11H2,1H3,(H,27,28)/b7-4+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Wyeth Research Curated by ChEMBL					Assay Description Inhibition of ITK				Bioorg Med Chem Lett 18: 4420-3 (2008) Article DOI: 10.1016/j.bmcl.2008.06.040 BindingDB Entry DOI: 10.7270/Q2WS8T2G
					More data for this Ligand-Target Pair

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