Compile Data Set for Download or QSAR

Found 116 hits Enz. Inhib. hit(s) with all data for entry = 50027688   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254766 (2-(3-(2,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc(Cl)cc3Cl)c12 Show InChI InChI=1S/C20H12Cl4N2O4S3/c21-10-4-5-15(11(22)6-10)31-16-8-25-13-2-1-3-14(19(13)16)30-9-17(27)26-33(28,29)18-7-12(23)20(24)32-18/h1-8,25H,9H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254687 (CHEMBL464032 | N-(4,5-dichlorothiophen-2-ylsulfony...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C24H16Cl2N2O4S3/c25-17-11-22(34-24(17)26)35(30,31)28-21(29)13-32-19-7-3-6-18-23(19)20(12-27-18)33-16-9-8-14-4-1-2-5-15(14)10-16/h1-12,27H,13H2,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254841 (2-(3-(3,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc(Cl)c(Cl)c3)c12 Show InChI InChI=1S/C20H12Cl4N2O4S3/c21-11-5-4-10(6-12(11)22)31-16-8-25-14-2-1-3-15(19(14)16)30-9-17(27)26-33(28,29)18-7-13(23)20(24)32-18/h1-8,25H,9H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Antagonist activity at human EP3 receptor assessed as cAMP production by cell-based assay				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254883 (CHEMBL479434 | N-(4,5-dichlorothiophen-2-ylsulfony...) Show SMILES COc1ccc(Sc2c[nH]c3cccc(OCC(=O)NS(=O)(=O)c4cc(Cl)c(Cl)s4)c23)cc1 Show InChI InChI=1S/C21H16Cl2N2O5S3/c1-29-12-5-7-13(8-6-12)31-17-10-24-15-3-2-4-16(20(15)17)30-11-18(26)25-33(27,28)19-9-14(22)21(23)32-19/h2-10,24H,11H2,1H3,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254728 (CHEMBL465947 | N-(4-methoxyphenylsulfonyl)-2-(3-(n...) Show SMILES COc1ccc(cc1)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C27H22N2O5S2/c1-33-20-10-13-22(14-11-20)36(31,32)29-26(30)17-34-24-8-4-7-23-27(24)25(16-28-23)35-21-12-9-18-5-2-3-6-19(18)15-21/h2-16,28H,17H2,1H3,(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254520 (CHEMBL466184 | N-(3,4-difluorophenylsulfonyl)-2-(3...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C26H18F2N2O4S2/c27-20-11-10-19(13-21(20)28)36(32,33)30-25(31)15-34-23-7-3-6-22-26(23)24(14-29-22)35-18-9-8-16-4-1-2-5-17(16)12-18/h1-14,29H,15H2,(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254647 (2-(3-(3,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(c12)S(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H12Cl4N2O6S3/c21-11-5-4-10(6-12(11)22)34(28,29)16-8-25-14-2-1-3-15(19(14)16)32-9-17(27)26-35(30,31)18-7-13(23)20(24)33-18/h1-8,25H,9H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Antagonist activity at human EP3 receptor assessed as cAMP production by cell-based assay				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254841 (2-(3-(3,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc(Cl)c(Cl)c3)c12 Show InChI InChI=1S/C20H12Cl4N2O4S3/c21-11-5-4-10(6-12(11)22)31-16-8-25-14-2-1-3-15(19(14)16)30-9-17(27)26-33(28,29)18-7-13(23)20(24)32-18/h1-8,25H,9H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254640 (CHEMBL482379 | N-(2,5-dimethoxyphenylsulfonyl)-2-(...) Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C28H24N2O6S2/c1-34-20-11-13-23(35-2)26(15-20)38(32,33)30-27(31)17-36-24-9-5-8-22-28(24)25(16-29-22)37-21-12-10-18-6-3-4-7-19(18)14-21/h3-16,29H,17H2,1-2H3,(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254841 (2-(3-(3,4-dichlorophenylthio)-1H-indol-4-yloxy)-N-...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc(Cl)c(Cl)c3)c12 Show InChI InChI=1S/C20H12Cl4N2O4S3/c21-11-5-4-10(6-12(11)22)31-16-8-25-14-2-1-3-15(19(14)16)30-9-17(27)26-33(28,29)18-7-13(23)20(24)32-18/h1-8,25H,9H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254768 (CHEMBL518396 | N-(4,5-dichlorothiophen-2-ylsulfony...) Show SMILES Cc1ccc(Sc2c[nH]c3cccc(OCC(=O)NS(=O)(=O)c4cc(Cl)c(Cl)s4)c23)c(C)c1 Show InChI InChI=1S/C22H18Cl2N2O4S3/c1-12-6-7-17(13(2)8-12)31-18-10-25-15-4-3-5-16(21(15)18)30-11-19(27)26-33(28,29)20-9-14(23)22(24)32-20/h3-10,25H,11H2,1-2H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254641 (CHEMBL482380 | N-(2-chlorophenylsulfonyl)-2-(3-(na...) Show SMILES Clc1ccccc1S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C26H19ClN2O4S2/c27-20-8-3-4-11-24(20)35(31,32)29-25(30)16-33-22-10-5-9-21-26(22)23(15-28-21)34-19-13-12-17-6-1-2-7-18(17)14-19/h1-15,28H,16H2,(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254880 (CHEMBL520741 | N-(4,5-dichlorothiophen-2-ylsulfony...) Show SMILES COc1ccc(Sc2c[nH]c3cccc(OCC(=O)NS(=O)(=O)c4cc(Cl)c(Cl)s4)c23)cc1OC Show InChI InChI=1S/C22H18Cl2N2O6S3/c1-30-15-7-6-12(8-17(15)31-2)33-18-10-25-14-4-3-5-16(21(14)18)32-11-19(27)26-35(28,29)20-9-13(23)22(24)34-20/h3-10,25H,11H2,1-2H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50255058 (CHEMBL479427 | N-(4,5-dichlorothiophen-2-ylsulfony...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(c12)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C24H16Cl2N2O6S3/c25-17-11-22(35-24(17)26)37(32,33)28-21(29)13-34-19-7-3-6-18-23(19)20(12-27-18)36(30,31)16-9-8-14-4-1-2-5-15(14)10-16/h1-12,27H,13H2,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254797 (2-(3-(2-chloro-4-fluorophenylthio)-1H-indol-4-ylox...) Show SMILES Fc1ccc(Sc2c[nH]c3cccc(OCC(=O)NS(=O)(=O)c4cc(Cl)c(Cl)s4)c23)c(Cl)c1 Show InChI InChI=1S/C20H12Cl3FN2O4S3/c21-11-6-10(24)4-5-15(11)31-16-8-25-13-2-1-3-14(19(13)16)30-9-17(27)26-33(28,29)18-7-12(22)20(23)32-18/h1-8,25H,9H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254767 (CHEMBL464271 | N-(4,5-dichlorothiophen-2-ylsulfony...) Show SMILES Fc1ccc(Sc2c[nH]c3cccc(OCC(=O)NS(=O)(=O)c4cc(Cl)c(Cl)s4)c23)c(F)c1 Show InChI InChI=1S/C20H12Cl2F2N2O4S3/c21-11-7-18(32-20(11)22)33(28,29)26-17(27)9-30-14-3-1-2-13-19(14)16(8-25-13)31-15-5-4-10(23)6-12(15)24/h1-8,25H,9H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Mus musculus (Mouse))	BDBM50254647 (2-(3-(3,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(c12)S(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H12Cl4N2O6S3/c21-11-5-4-10(6-12(11)22)34(28,29)16-8-25-14-2-1-3-15(19(14)16)32-9-17(27)26-35(30,31)18-7-13(23)20(24)33-18/h1-8,25H,9H2,(H,26,27)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from mouse EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254520 (CHEMBL466184 | N-(3,4-difluorophenylsulfonyl)-2-(3...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C26H18F2N2O4S2/c27-20-11-10-19(13-21(20)28)36(32,33)30-25(31)15-34-23-7-3-6-22-26(23)24(14-29-22)35-18-9-8-16-4-1-2-5-17(16)12-18/h1-14,29H,15H2,(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254686 (CHEMBL464031 | N-(3-chlorophenylsulfonyl)-2-(3-(na...) Show SMILES Clc1cccc(c1)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C26H19ClN2O4S2/c27-19-7-3-8-21(14-19)35(31,32)29-25(30)16-33-23-10-4-9-22-26(23)24(15-28-22)34-20-12-11-17-5-1-2-6-18(17)13-20/h1-15,28H,16H2,(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254730 (2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)-N-(ph...) Show SMILES O=C(COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C26H20N2O4S2/c29-25(28-34(30,31)21-9-2-1-3-10-21)17-32-23-12-6-11-22-26(23)24(16-27-22)33-20-14-13-18-7-4-5-8-19(18)15-20/h1-16,27H,17H2,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254686 (CHEMBL464031 | N-(3-chlorophenylsulfonyl)-2-(3-(na...) Show SMILES Clc1cccc(c1)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C26H19ClN2O4S2/c27-19-7-3-8-21(14-19)35(31,32)29-25(30)16-33-23-10-4-9-22-26(23)24(15-28-22)34-20-12-11-17-5-1-2-6-18(17)13-20/h1-15,28H,16H2,(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254643 (CHEMBL481589 | N-(3,5-dichlorophenylsulfonyl)-2-(3...) Show SMILES Clc1cc(Cl)cc(c1)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C26H18Cl2N2O4S2/c27-18-11-19(28)13-21(12-18)36(32,33)30-25(31)15-34-23-7-3-6-22-26(23)24(14-29-22)35-20-9-8-16-4-1-2-5-17(16)10-20/h1-14,29H,15H2,(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254924 (CHEMBL465923 | N-(4,5-dichlorothiophen-2-ylsulfony...) Show SMILES Cn1c(Sc2c[nH]c3cccc(OCC(=O)NS(=O)(=O)c4cc(Cl)c(Cl)s4)c23)nc2ccccc12 Show InChI InChI=1S/C22H16Cl2N4O4S3/c1-28-15-7-3-2-5-13(15)26-22(28)33-17-10-25-14-6-4-8-16(20(14)17)32-11-18(29)27-35(30,31)19-9-12(23)21(24)34-19/h2-10,25H,11H2,1H3,(H,27,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254797 (2-(3-(2-chloro-4-fluorophenylthio)-1H-indol-4-ylox...) Show SMILES Fc1ccc(Sc2c[nH]c3cccc(OCC(=O)NS(=O)(=O)c4cc(Cl)c(Cl)s4)c23)c(Cl)c1 Show InChI InChI=1S/C20H12Cl3FN2O4S3/c21-11-6-10(24)4-5-15(11)31-16-8-25-13-2-1-3-14(19(13)16)30-9-17(27)26-33(28,29)18-7-12(22)20(23)32-18/h1-8,25H,9H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254838 (CHEMBL481582 | N-(4,5-dichlorothiophen-2-ylsulfony...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccccn3)c12 Show InChI InChI=1S/C19H13Cl2N3O4S3/c20-11-8-17(30-19(11)21)31(26,27)24-15(25)10-28-13-5-3-4-12-18(13)14(9-23-12)29-16-6-1-2-7-22-16/h1-9,23H,10H2,(H,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254473 (4,5-Dichlorothiophene-2-sulfonic Acid[2-(3-Naphtha...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Cc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C25H18Cl2N2O4S2/c26-19-12-23(34-25(19)27)35(31,32)29-22(30)14-33-21-7-3-6-20-24(21)18(13-28-20)11-15-8-9-16-4-1-2-5-17(16)10-15/h1-10,12-13,28H,11,14H2,(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254642 (2-(3-(naphthalen-2-ylthio)-1H-indol-4-yloxy)-N-(th...) Show SMILES O=C(COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12)NS(=O)(=O)c1cccs1 Show InChI InChI=1S/C24H18N2O4S3/c27-22(26-33(28,29)23-9-4-12-31-23)15-30-20-8-3-7-19-24(20)21(14-25-19)32-18-11-10-16-5-1-2-6-17(16)13-18/h1-14,25H,15H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254882 (2-(3-(4-chlorophenylthio)-1H-indol-4-yloxy)-N-(4,5...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C20H13Cl3N2O4S3/c21-11-4-6-12(7-5-11)30-16-9-24-14-2-1-3-15(19(14)16)29-10-17(26)25-32(27,28)18-8-13(22)20(23)31-18/h1-9,24H,10H2,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254881 (2-(3-(4-(2-amino-2-oxoethyl)phenylthio)-1H-indol-4...) Show SMILES NC(=O)Cc1ccc(Sc2c[nH]c3cccc(OCC(=O)NS(=O)(=O)c4cc(Cl)c(Cl)s4)c23)cc1 Show InChI InChI=1S/C22H17Cl2N3O5S3/c23-14-9-20(34-22(14)24)35(30,31)27-19(29)11-32-16-3-1-2-15-21(16)17(10-26-15)33-13-6-4-12(5-7-13)8-18(25)28/h1-7,9-10,26H,8,11H2,(H2,25,28)(H,27,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254729 (CHEMBL517165 | N-(5-chlorothiophen-2-ylsulfonyl)-2...) Show SMILES Clc1ccc(s1)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C24H17ClN2O4S3/c25-21-10-11-23(33-21)34(29,30)27-22(28)14-31-19-7-3-6-18-24(19)20(13-26-18)32-17-9-8-15-4-1-2-5-16(15)12-17/h1-13,26H,14H2,(H,27,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254643 (CHEMBL481589 | N-(3,5-dichlorophenylsulfonyl)-2-(3...) Show SMILES Clc1cc(Cl)cc(c1)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C26H18Cl2N2O4S2/c27-18-11-19(28)13-21(12-18)36(32,33)30-25(31)15-34-23-7-3-6-22-26(23)24(14-29-22)35-20-9-8-16-4-1-2-5-17(16)10-20/h1-14,29H,15H2,(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254647 (2-(3-(3,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(c12)S(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H12Cl4N2O6S3/c21-11-5-4-10(6-12(11)22)34(28,29)16-8-25-14-2-1-3-15(19(14)16)32-9-17(27)26-35(30,31)18-7-13(23)20(24)33-18/h1-8,25H,9H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254964 (CHEMBL517180 | N-(3,4-difluorophenylsulfonyl)-2-(3...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(c12)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C26H18F2N2O6S2/c27-20-11-10-19(13-21(20)28)38(34,35)30-25(31)15-36-23-7-3-6-22-26(23)24(14-29-22)37(32,33)18-9-8-16-4-1-2-5-17(16)12-18/h1-14,29H,15H2,(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.60	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254839 (CHEMBL520933 | N-(4,5-dichlorothiophen-2-ylsulfony...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4n3)c12 Show InChI InChI=1S/C23H15Cl2N3O4S3/c24-14-10-21(34-23(14)25)35(30,31)28-19(29)12-32-17-7-3-6-16-22(17)18(11-26-16)33-20-9-8-13-4-1-2-5-15(13)27-20/h1-11,26H,12H2,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50255026 (CHEMBL480992 | N-(3,5-difluorophenylsulfonyl)-2-(3...) Show SMILES Fc1cc(F)cc(c1)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(c12)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C26H18F2N2O6S2/c27-18-11-19(28)13-21(12-18)38(34,35)30-25(31)15-36-23-7-3-6-22-26(23)24(14-29-22)37(32,33)20-9-8-16-4-1-2-5-17(16)10-20/h1-14,29H,15H2,(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254882 (2-(3-(4-chlorophenylthio)-1H-indol-4-yloxy)-N-(4,5...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc(Cl)cc3)c12 Show InChI InChI=1S/C20H13Cl3N2O4S3/c21-11-4-6-12(7-5-11)30-16-9-24-14-2-1-3-15(19(14)16)29-10-17(26)25-32(27,28)18-8-13(22)20(23)31-18/h1-9,24H,10H2,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254684 (CHEMBL481004 | N-(3,5-difluorophenylsulfonyl)-2-(3...) Show SMILES Fc1cc(F)cc(c1)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C26H18F2N2O4S2/c27-18-11-19(28)13-21(12-18)36(32,33)30-25(31)15-34-23-7-3-6-22-26(23)24(14-29-22)35-20-9-8-16-4-1-2-5-17(16)10-20/h1-14,29H,15H2,(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.20	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254729 (CHEMBL517165 | N-(5-chlorothiophen-2-ylsulfonyl)-2...) Show SMILES Clc1ccc(s1)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C24H17ClN2O4S3/c25-21-10-11-23(33-21)34(29,30)27-22(28)14-31-19-7-3-6-18-24(19)20(13-26-18)32-17-9-8-15-4-1-2-5-16(15)12-17/h1-13,26H,14H2,(H,27,28)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254839 (CHEMBL520933 | N-(4,5-dichlorothiophen-2-ylsulfony...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4n3)c12 Show InChI InChI=1S/C23H15Cl2N3O4S3/c24-14-10-21(34-23(14)25)35(30,31)28-19(29)12-32-17-7-3-6-16-22(17)18(11-26-16)33-20-9-8-13-4-1-2-5-15(13)27-20/h1-11,26H,12H2,(H,28,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254647 (2-(3-(3,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(c12)S(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H12Cl4N2O6S3/c21-11-5-4-10(6-12(11)22)34(28,29)16-8-25-14-2-1-3-15(19(14)16)32-9-17(27)26-35(30,31)18-7-13(23)20(24)33-18/h1-8,25H,9H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254689 (2-(3-(4-(2-amino-2-oxoethyl)phenylsulfonyl)-1H-ind...) Show SMILES NC(=O)Cc1ccc(cc1)S(=O)(=O)c1c[nH]c2cccc(OCC(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)c12 Show InChI InChI=1S/C22H17Cl2N3O7S3/c23-14-9-20(35-22(14)24)37(32,33)27-19(29)11-34-16-3-1-2-15-21(16)17(10-26-15)36(30,31)13-6-4-12(5-7-13)8-18(25)28/h1-7,9-10,26H,8,11H2,(H2,25,28)(H,27,29)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254768 (CHEMBL518396 | N-(4,5-dichlorothiophen-2-ylsulfony...) Show SMILES Cc1ccc(Sc2c[nH]c3cccc(OCC(=O)NS(=O)(=O)c4cc(Cl)c(Cl)s4)c23)c(C)c1 Show InChI InChI=1S/C22H18Cl2N2O4S3/c1-12-6-7-17(13(2)8-12)31-18-10-25-15-4-3-5-16(21(15)18)30-11-19(27)26-33(28,29)20-9-14(23)22(24)32-20/h3-10,25H,11H2,1-2H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254923 (CHEMBL518110 | N-(4,5-dichlorothiophen-2-ylsulfony...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccccc3)c12 Show InChI InChI=1S/C20H14Cl2N2O4S3/c21-13-9-18(30-20(13)22)31(26,27)24-17(25)11-28-15-8-4-7-14-19(15)16(10-23-14)29-12-5-2-1-3-6-12/h1-10,23H,11H2,(H,24,25)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50255092 (2-(3-(2,4-dichlorophenylsulfonyl)-1H-indol-4-yloxy...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(c12)S(=O)(=O)c1ccc(Cl)cc1Cl Show InChI InChI=1S/C20H12Cl4N2O6S3/c21-10-4-5-15(11(22)6-10)34(28,29)16-8-25-13-2-1-3-14(19(13)16)32-9-17(27)26-35(30,31)18-7-12(23)20(24)33-18/h1-8,25H,9H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.60	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50255094 (CHEMBL518109 | N-(4,5-dichlorothiophen-2-ylsulfony...) Show SMILES Cc1ccc(c(C)c1)S(=O)(=O)c1c[nH]c2cccc(OCC(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)c12 Show InChI InChI=1S/C22H18Cl2N2O6S3/c1-12-6-7-17(13(2)8-12)34(28,29)18-10-25-15-4-3-5-16(21(15)18)32-11-19(27)26-35(30,31)20-9-14(23)22(24)33-20/h3-10,25H,11H2,1-2H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254684 (CHEMBL481004 | N-(3,5-difluorophenylsulfonyl)-2-(3...) Show SMILES Fc1cc(F)cc(c1)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C26H18F2N2O4S2/c27-18-11-19(28)13-21(12-18)36(32,33)30-25(31)15-34-23-7-3-6-22-26(23)24(14-29-22)35-20-9-8-16-4-1-2-5-17(16)10-20/h1-14,29H,15H2,(H,30,31)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.70	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254798 (2-(3-(2-chlorophenylthio)-1H-indol-4-yloxy)-N-(4,5...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(Sc3ccccc3Cl)c12 Show InChI InChI=1S/C20H13Cl3N2O4S3/c21-11-4-1-2-7-15(11)30-16-9-24-13-5-3-6-14(19(13)16)29-10-17(26)25-32(27,28)18-8-12(22)20(23)31-18/h1-9,24H,10H2,(H,25,26)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50255028 (CHEMBL520425 | N-(3-chlorophenylsulfonyl)-2-(3-(na...) Show SMILES Clc1cccc(c1)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(c12)S(=O)(=O)c1ccc2ccccc2c1 Show InChI InChI=1S/C26H19ClN2O6S2/c27-19-7-3-8-21(14-19)37(33,34)29-25(30)16-35-23-10-4-9-22-26(23)24(15-28-22)36(31,32)20-12-11-17-5-1-2-6-18(17)13-20/h1-15,28H,16H2,(H,29,30)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254475 (CHEMBL466595 | N-(4,5-dichlorothiophen-2-ylsulfony...) Show SMILES COc1ccc(OC)c(c1)S(=O)(=O)c1c[nH]c2cccc(OCC(=O)NS(=O)(=O)c3cc(Cl)c(Cl)s3)c12 Show InChI InChI=1S/C22H18Cl2N2O8S3/c1-32-12-6-7-15(33-2)17(8-12)36(28,29)18-10-25-14-4-3-5-16(21(14)18)34-11-19(27)26-37(30,31)20-9-13(23)22(24)35-20/h3-10,25H,11H2,1-2H3,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50254476 (2-(3-(benzo[d]thiazol-2-ylsulfonyl)-1H-indol-4-ylo...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)COc1cccc2[nH]cc(c12)S(=O)(=O)c1nc2ccccc2s1 Show InChI InChI=1S/C21H13Cl2N3O6S4/c22-11-8-18(34-20(11)23)36(30,31)26-17(27)10-32-14-6-3-5-13-19(14)16(9-24-13)35(28,29)21-25-12-4-1-2-7-15(12)33-21/h1-9,24H,10H2,(H,26,27)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	7.60	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry, Inc Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 19: 123-6 (2008) Article DOI: 10.1016/j.bmcl.2008.11.007 BindingDB Entry DOI: 10.7270/Q2JH3M1S
					More data for this Ligand-Target Pair

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