Compile Data Set for Download or QSAR

Found 81 hits Enz. Inhib. hit(s) with all data for entry = 50028392   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257624 (7-(phenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]a...) Show SMILES O=S(=O)(c1ccccc1)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C16H17NO2S/c18-20(19,15-4-2-1-3-5-15)16-7-6-13-8-10-17-11-9-14(13)12-16/h1-7,12,17H,8-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257613 (CHEMBL493951 | N-(cyclopropylmethyl)-N-methyl-2,3,...) Show SMILES CN(CC1CC1)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C15H22N2O2S/c1-17(11-12-2-3-12)20(18,19)15-5-4-13-6-8-16-9-7-14(13)10-15/h4-5,10,12,16H,2-3,6-9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257615 (7-(piperidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-b...) Show SMILES O=S(=O)(N1CCCCC1)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C15H22N2O2S/c18-20(19,17-10-2-1-3-11-17)15-5-4-13-6-8-16-9-7-14(13)12-15/h4-5,12,16H,1-3,6-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257612 (CHEMBL493950 | N-benzyl-N-methyl-2,3,4,5-tetrahydr...) Show SMILES CN(Cc1ccccc1)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C18H22N2O2S/c1-20(14-15-5-3-2-4-6-15)23(21,22)18-8-7-16-9-11-19-12-10-17(16)13-18/h2-8,13,19H,9-12,14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257621 (7-(4-(2-chlorophenoxy)piperidin-1-ylsulfonyl)-2,3,...) Show SMILES Clc1ccccc1OC1CCN(CC1)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C21H25ClN2O3S/c22-20-3-1-2-4-21(20)27-18-9-13-24(14-10-18)28(25,26)19-6-5-16-7-11-23-12-8-17(16)15-19/h1-6,15,18,23H,7-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257620 (7-(4-(2-fluorophenoxy)piperidin-1-ylsulfonyl)-2,3,...) Show SMILES Fc1ccccc1OC1CCN(CC1)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C21H25FN2O3S/c22-20-3-1-2-4-21(20)27-18-9-13-24(14-10-18)28(25,26)19-6-5-16-7-11-23-12-8-17(16)15-19/h1-6,15,18,23H,7-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257563 (CHEMBL492349 | N-(2-chlorobenzyl)-2,3,4,5-tetrahyd...) Show SMILES Clc1ccccc1CNS(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C17H19ClN2O2S/c18-17-4-2-1-3-15(17)12-20-23(21,22)16-6-5-13-7-9-19-10-8-14(13)11-16/h1-6,11,19-20H,7-10,12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257614 (7-(pyrrolidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-...) Show SMILES O=S(=O)(N1CCCC1)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C14H20N2O2S/c17-19(18,16-9-1-2-10-16)14-4-3-12-5-7-15-8-6-13(12)11-14/h3-4,11,15H,1-2,5-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	51	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257617 (CHEMBL492556 | N-((2,3-dihydrobenzofuran-3-yl)meth...) Show SMILES CN(CC1COc2ccccc12)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C20H24N2O3S/c1-22(13-17-14-25-20-5-3-2-4-19(17)20)26(23,24)18-7-6-15-8-10-21-11-9-16(15)12-18/h2-7,12,17,21H,8-11,13-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257565 (CHEMBL492949 | N,N-dimethyl-2,3,4,5-tetrahydro-1H-...) Show SMILES CN(C)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C12H18N2O2S/c1-14(2)17(15,16)12-4-3-10-5-7-13-8-6-11(10)9-12/h3-4,9,13H,5-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	87	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257611 (CHEMBL522349 | N-(2-fluorophenyl)-2,3,4,5-tetrahyd...) Show SMILES Fc1ccccc1NS(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C16H17FN2O2S/c17-15-3-1-2-4-16(15)19-22(20,21)14-6-5-12-7-9-18-10-8-13(12)11-14/h1-6,11,18-19H,7-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	133	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257562 (CHEMBL492348 | N-(2-chlorophenyl)-2,3,4,5-tetrahyd...) Show SMILES Clc1ccccc1NS(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C16H17ClN2O2S/c17-15-3-1-2-4-16(15)19-22(20,21)14-6-5-12-7-9-18-10-8-13(12)11-14/h1-6,11,18-19H,7-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	156	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257616 (4-(2,3,4,5-tetrahydro-1H-benzo[d]azepin-7-ylsulfon...) Show SMILES O=S(=O)(N1CCOCC1)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C14H20N2O3S/c17-20(18,16-7-9-19-10-8-16)14-2-1-12-3-5-15-6-4-13(12)11-14/h1-2,11,15H,3-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	196	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257564 (CHEMBL511044 | N-(cyclopropylmethyl)-2,3,4,5-tetra...) Show SMILES O=S(=O)(NCC1CC1)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C14H20N2O2S/c17-19(18,16-10-11-1-2-11)14-4-3-12-5-7-15-8-6-13(12)9-14/h3-4,9,11,15-16H,1-2,5-8,10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	235	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257610 (CHEMBL493152 | N-phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES O=S(=O)(Nc1ccccc1)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C16H18N2O2S/c19-21(20,18-15-4-2-1-3-5-15)16-7-6-13-8-10-17-11-9-14(13)12-16/h1-7,12,17-18H,8-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	382	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257609 (CHEMBL493151 | N-propyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES CCCNS(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C13H20N2O2S/c1-2-7-15-18(16,17)13-4-3-11-5-8-14-9-6-12(11)10-13/h3-4,10,14-15H,2,5-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	531	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257566 (CHEMBL492950 | N-methyl-N-phenyl-2,3,4,5-tetrahydr...) Show SMILES CN(c1ccccc1)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C17H20N2O2S/c1-19(16-5-3-2-4-6-16)22(20,21)17-8-7-14-9-11-18-12-10-15(14)13-17/h2-8,13,18H,9-12H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]mesulergine form human recombinant 5HT2C receptor expressed in mouse Swiss 3T3 cells by scintillation proximity assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50257570 (7-(3-(4-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4...) Show SMILES Clc1ccc(OC2CN(C2)S(=O)(=O)c2ccc3CCNCCc3c2)cc1 Show InChI InChI=1S/C19H21ClN2O3S/c20-16-2-4-17(5-3-16)25-18-12-22(13-18)26(23,24)19-6-1-14-7-9-21-10-8-15(14)11-19/h1-6,11,18,21H,7-10,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.09E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50257621 (7-(4-(2-chlorophenoxy)piperidin-1-ylsulfonyl)-2,3,...) Show SMILES Clc1ccccc1OC1CCN(CC1)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C21H25ClN2O3S/c22-20-3-1-2-4-21(20)27-18-9-13-24(14-10-18)28(25,26)19-6-5-16-7-11-23-12-8-17(16)15-19/h1-6,15,18,23H,7-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50257617 (CHEMBL492556 | N-((2,3-dihydrobenzofuran-3-yl)meth...) Show SMILES CN(CC1COc2ccccc12)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C20H24N2O3S/c1-22(13-17-14-25-20-5-3-2-4-19(17)20)26(23,24)18-7-6-15-8-10-21-11-9-16(15)12-18/h2-7,12,17,21H,8-11,13-14H2,1H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.99E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50257568 (7-(3-(2-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4...) Show SMILES Clc1ccccc1OC1CN(C1)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C19H21ClN2O3S/c20-18-3-1-2-4-19(18)25-16-12-22(13-16)26(23,24)17-6-5-14-7-9-21-10-8-15(14)11-17/h1-6,11,16,21H,7-10,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.41E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50257571 ((R)-7-(3-(2-chlorophenoxy)pyrrolidin-1-ylsulfonyl)...) Show SMILES Clc1ccccc1O[C@@H]1CCN(C1)S(=O)(=O)c1ccc2CCNCCc2c1 |r| Show InChI InChI=1S/C20H23ClN2O3S/c21-19-3-1-2-4-20(19)26-17-9-12-23(14-17)27(24,25)18-6-5-15-7-10-22-11-8-16(15)13-18/h1-6,13,17,22H,7-12,14H2/t17-/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.43E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50257569 (7-(3-(3-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4...) Show SMILES Clc1cccc(OC2CN(C2)S(=O)(=O)c2ccc3CCNCCc3c2)c1 Show InChI InChI=1S/C19H21ClN2O3S/c20-16-2-1-3-17(11-16)25-18-12-22(13-18)26(23,24)19-5-4-14-6-8-21-9-7-15(14)10-19/h1-5,10-11,18,21H,6-9,12-13H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.69E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50257618 ((S)-7-(3-(2-chlorophenoxy)pyrrolidin-1-ylsulfonyl)...) Show SMILES Clc1ccccc1O[C@H]1CCN(C1)S(=O)(=O)c1ccc2CCNCCc2c1 |r| Show InChI InChI=1S/C20H23ClN2O3S/c21-19-3-1-2-4-20(19)26-17-9-12-23(14-17)27(24,25)18-6-5-15-7-10-22-11-8-16(15)13-18/h1-6,13,17,22H,7-12,14H2/t17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.24E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50257624 (7-(phenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]a...) Show SMILES O=S(=O)(c1ccccc1)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C16H17NO2S/c18-20(19,15-4-2-1-3-5-15)16-7-6-13-8-10-17-11-9-14(13)12-16/h1-7,12,17H,8-11H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>7.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity to human ERG				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50257621 (7-(4-(2-chlorophenoxy)piperidin-1-ylsulfonyl)-2,3,...) Show SMILES Clc1ccccc1OC1CCN(CC1)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C21H25ClN2O3S/c22-20-3-1-2-4-21(20)27-18-9-13-24(14-10-18)28(25,26)19-6-5-16-7-11-23-12-8-17(16)15-19/h1-6,15,18,23H,7-14H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	32	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human 5HT2A receptor expressed in mouse Swiss 3T3 cells by FLIPR assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257625 (7-(2-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-b...) Show SMILES Fc1ccccc1S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C16H16FNO2S/c17-15-3-1-2-4-16(15)21(19,20)14-6-5-12-7-9-18-10-8-13(12)11-14/h1-6,11,18H,7-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	7	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257624 (7-(phenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]a...) Show SMILES O=S(=O)(c1ccccc1)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C16H17NO2S/c18-20(19,15-4-2-1-3-5-15)16-7-6-13-8-10-17-11-9-14(13)12-16/h1-7,12,17H,8-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257626 (7-(3-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-b...) Show SMILES Fc1cccc(c1)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C16H16FNO2S/c17-14-2-1-3-15(11-14)21(19,20)16-5-4-12-6-8-18-9-7-13(12)10-16/h1-5,10-11,18H,6-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	9	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257569 (7-(3-(3-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4...) Show SMILES Clc1cccc(OC2CN(C2)S(=O)(=O)c2ccc3CCNCCc3c2)c1 Show InChI InChI=1S/C19H21ClN2O3S/c20-16-2-1-3-17(11-16)25-18-12-22(13-18)26(23,24)19-5-4-14-6-8-21-9-7-15(14)10-19/h1-5,10-11,18,21H,6-9,12-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	12	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257571 ((R)-7-(3-(2-chlorophenoxy)pyrrolidin-1-ylsulfonyl)...) Show SMILES Clc1ccccc1O[C@@H]1CCN(C1)S(=O)(=O)c1ccc2CCNCCc2c1 |r| Show InChI InChI=1S/C20H23ClN2O3S/c21-19-3-1-2-4-20(19)26-17-9-12-23(14-17)27(24,25)18-6-5-15-7-10-22-11-8-16(15)13-18/h1-6,13,17,22H,7-12,14H2/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50257627 (7-(4-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-b...) Show SMILES Fc1ccc(cc1)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C16H16FNO2S/c17-14-2-5-15(6-3-14)21(19,20)16-4-1-12-7-9-18-10-8-13(12)11-16/h1-6,11,18H,7-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor by cell-based system				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50257613 (CHEMBL493951 | N-(cyclopropylmethyl)-N-methyl-2,3,...) Show SMILES CN(CC1CC1)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C15H22N2O2S/c1-17(11-12-2-3-12)20(18,19)15-5-4-13-6-8-16-9-7-14(13)10-15/h4-5,10,12,16H,2-3,6-9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	17	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor by cell-based system				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50257624 (7-(phenylsulfonyl)-2,3,4,5-tetrahydro-1H-benzo[d]a...) Show SMILES O=S(=O)(c1ccccc1)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C16H17NO2S/c18-20(19,15-4-2-1-3-5-15)16-7-6-13-8-10-17-11-9-14(13)12-16/h1-7,12,17H,8-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor by cell-based system				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50257625 (7-(2-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-b...) Show SMILES Fc1ccccc1S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C16H16FNO2S/c17-15-3-1-2-4-16(15)21(19,20)14-6-5-12-7-9-18-10-8-13(12)11-14/h1-6,11,18H,7-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	18	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor by cell-based system				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257570 (7-(3-(4-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4...) Show SMILES Clc1ccc(OC2CN(C2)S(=O)(=O)c2ccc3CCNCCc3c2)cc1 Show InChI InChI=1S/C19H21ClN2O3S/c20-16-2-4-17(5-3-16)25-18-12-22(13-18)26(23,24)19-6-1-14-7-9-21-10-8-15(14)11-19/h1-6,11,18,21H,7-10,12-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	28	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257568 (7-(3-(2-chlorophenoxy)azetidin-1-ylsulfonyl)-2,3,4...) Show SMILES Clc1ccccc1OC1CN(C1)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C19H21ClN2O3S/c20-18-3-1-2-4-19(18)25-16-12-22(13-16)26(23,24)17-6-5-14-7-9-21-10-8-15(14)11-17/h1-6,11,16,21H,7-10,12-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257618 ((S)-7-(3-(2-chlorophenoxy)pyrrolidin-1-ylsulfonyl)...) Show SMILES Clc1ccccc1O[C@H]1CCN(C1)S(=O)(=O)c1ccc2CCNCCc2c1 |r| Show InChI InChI=1S/C20H23ClN2O3S/c21-19-3-1-2-4-20(19)26-17-9-12-23(14-17)27(24,25)18-6-5-15-7-10-22-11-8-16(15)13-18/h1-6,13,17,22H,7-12,14H2/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257621 (7-(4-(2-chlorophenoxy)piperidin-1-ylsulfonyl)-2,3,...) Show SMILES Clc1ccccc1OC1CCN(CC1)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C21H25ClN2O3S/c22-20-3-1-2-4-21(20)27-18-9-13-24(14-10-18)28(25,26)19-6-5-16-7-11-23-12-8-17(16)15-19/h1-6,15,18,23H,7-14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50257626 (7-(3-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-b...) Show SMILES Fc1cccc(c1)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C16H16FNO2S/c17-14-2-1-3-15(11-14)21(19,20)16-5-4-12-6-8-18-9-7-13(12)10-16/h1-5,10-11,18H,6-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	33	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor by cell-based system				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50257615 (7-(piperidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-b...) Show SMILES O=S(=O)(N1CCCCC1)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C15H22N2O2S/c18-20(19,17-10-2-1-3-11-17)15-5-4-13-6-8-16-9-7-14(13)12-15/h4-5,12,16H,1-3,6-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	34	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor by cell-based system				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257617 (CHEMBL492556 | N-((2,3-dihydrobenzofuran-3-yl)meth...) Show SMILES CN(CC1COc2ccccc12)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C20H24N2O3S/c1-22(13-17-14-25-20-5-3-2-4-19(17)20)26(23,24)18-7-6-15-8-10-21-11-9-16(15)12-18/h2-7,12,17,21H,8-11,13-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	41	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257563 (CHEMBL492349 | N-(2-chlorobenzyl)-2,3,4,5-tetrahyd...) Show SMILES Clc1ccccc1CNS(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C17H19ClN2O2S/c18-17-4-2-1-3-15(17)12-20-23(21,22)16-6-5-13-7-9-19-10-8-14(13)11-16/h1-6,11,19-20H,7-10,12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257565 (CHEMBL492949 | N,N-dimethyl-2,3,4,5-tetrahydro-1H-...) Show SMILES CN(C)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C12H18N2O2S/c1-14(2)17(15,16)12-4-3-10-5-7-13-8-6-11(10)9-12/h3-4,9,13H,5-8H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	47	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257614 (7-(pyrrolidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-...) Show SMILES O=S(=O)(N1CCCC1)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C14H20N2O2S/c17-19(18,16-9-1-2-10-16)14-4-3-12-5-7-15-8-6-13(12)11-14/h3-4,11,15H,1-2,5-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50257610 (CHEMBL493152 | N-phenyl-2,3,4,5-tetrahydro-1H-benz...) Show SMILES O=S(=O)(Nc1ccccc1)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C16H18N2O2S/c19-21(20,18-15-4-2-1-3-5-15)16-7-6-13-8-10-17-11-9-14(13)12-16/h1-7,12,17-18H,8-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	69	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor by cell-based system				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257613 (CHEMBL493951 | N-(cyclopropylmethyl)-N-methyl-2,3,...) Show SMILES CN(CC1CC1)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C15H22N2O2S/c1-17(11-12-2-3-12)20(18,19)15-5-4-13-6-8-16-9-7-14(13)10-15/h4-5,10,12,16H,2-3,6-9,11H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	71	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2B (Homo sapiens (Human))	BDBM50257611 (CHEMBL522349 | N-(2-fluorophenyl)-2,3,4,5-tetrahyd...) Show SMILES Fc1ccccc1NS(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C16H17FN2O2S/c17-15-3-1-2-4-16(15)19-22(20,21)14-6-5-12-7-9-18-10-8-13(12)11-14/h1-6,11,18-19H,7-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	75	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2B receptor by cell-based system				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257627 (7-(4-fluorophenylsulfonyl)-2,3,4,5-tetrahydro-1H-b...) Show SMILES Fc1ccc(cc1)S(=O)(=O)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C16H16FNO2S/c17-14-2-5-15(6-3-14)21(19,20)16-4-1-12-7-9-18-10-8-13(12)11-16/h1-6,11,18H,7-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	80	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50257615 (7-(piperidin-1-ylsulfonyl)-2,3,4,5-tetrahydro-1H-b...) Show SMILES O=S(=O)(N1CCCCC1)c1ccc2CCNCCc2c1 Show InChI InChI=1S/C15H22N2O2S/c18-20(19,17-10-2-1-3-11-17)15-5-4-13-6-8-16-9-7-14(13)12-15/h4-5,12,16H,1-3,6-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	84	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Agonist activity at human recombinant 5HT2C receptor expressed in CHOK1 cells assessed as calcium mobilization by FLIPR assay				Bioorg Med Chem Lett 19: 1871-5 (2009) Article DOI: 10.1016/j.bmcl.2009.02.071 BindingDB Entry DOI: 10.7270/Q2GB23XH
					More data for this Ligand-Target Pair

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