Compile Data Set for Download or QSAR

Found 30 hits Enz. Inhib. hit(s) with all data for entry = 50046978   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM60875 (3-((6-(4,5-Dihydro-1H-benzo[d]azepin-3(2H)-yl)-2-(...) Show SMILES OC(=O)CCNc1cc(nc(n1)-c1ccccn1)N1CCc2ccccc2CC1 Show InChI InChI=1S/C22H23N5O2/c28-21(29)8-12-24-19-15-20(26-22(25-19)18-7-3-4-11-23-18)27-13-9-16-5-1-2-6-17(16)10-14-27/h1-7,11,15H,8-10,12-14H2,(H,28,29)(H,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid PDB UniChem	PDB Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140574 (CHEMBL3753391) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1cccn1)N1CCc2ccccc2CC1 Show InChI InChI=1S/C20H22N6O2/c27-19(28)6-10-21-20-23-17(14-18(24-20)26-11-3-9-22-26)25-12-7-15-4-1-2-5-16(15)8-13-25/h1-5,9,11,14H,6-8,10,12-13H2,(H,27,28)(H,21,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140567 (CHEMBL3752893) Show SMILES OC(=O)CCNc1nc(cc(n1)-c1nccs1)N1CCc2ccccc2CC1 Show InChI InChI=1S/C20H21N5O2S/c26-18(27)5-8-22-20-23-16(19-21-9-12-28-19)13-17(24-20)25-10-6-14-3-1-2-4-15(14)7-11-25/h1-4,9,12-13H,5-8,10-11H2,(H,26,27)(H,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140345 (CHEMBL3752179) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1ccnn1)N1CCc2ccccc2CC1 Show InChI InChI=1S/C19H21N7O2/c27-18(28)5-8-20-19-22-16(13-17(23-19)26-12-9-21-24-26)25-10-6-14-3-1-2-4-15(14)7-11-25/h1-4,9,12-13H,5-8,10-11H2,(H,27,28)(H,20,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	210	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140680 (CHEMBL3753740) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1nccn1)N1CCc2ccccc2CC1 Show InChI InChI=1S/C19H21N7O2/c27-18(28)5-8-20-19-23-16(13-17(24-19)26-21-9-10-22-26)25-11-6-14-3-1-2-4-15(14)7-12-25/h1-4,9-10,13H,5-8,11-12H2,(H,27,28)(H,20,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	270	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140678 (CHEMBL3752769) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1cccn1)N1CCc2ccccc2C1 Show InChI InChI=1S/C19H20N6O2/c26-18(27)6-9-20-19-22-16(12-17(23-19)25-10-3-8-21-25)24-11-7-14-4-1-2-5-15(14)13-24/h1-5,8,10,12H,6-7,9,11,13H2,(H,26,27)(H,20,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140576 (CHEMBL3752835) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1cccn1)N1CCN(CC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H22FN7O2/c21-15-2-4-16(5-3-15)26-10-12-27(13-11-26)17-14-18(28-9-1-7-23-28)25-20(24-17)22-8-6-19(29)30/h1-5,7,9,14H,6,8,10-13H2,(H,29,30)(H,22,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140570 (CHEMBL3752143) Show SMILES OC(=O)CCNc1nc(cc(n1)-c1nccs1)N1CCN(CC1)c1ccc(F)cc1 Show InChI InChI=1S/C20H21FN6O2S/c21-14-1-3-15(4-2-14)26-8-10-27(11-9-26)17-13-16(19-22-7-12-30-19)24-20(25-17)23-6-5-18(28)29/h1-4,7,12-13H,5-6,8-11H2,(H,28,29)(H,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140677 (CHEMBL3752551) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1cccn1)N1CCN(CC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H21Cl2N7O2/c21-15-3-2-14(12-16(15)22)27-8-10-28(11-9-27)17-13-18(29-7-1-5-24-29)26-20(25-17)23-6-4-19(30)31/h1-3,5,7,12-13H,4,6,8-11H2,(H,30,31)(H,23,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	740	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140575 (CHEMBL3753449) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1cccn1)N1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C21H24N6O2/c28-20(29)7-11-22-21-24-18(15-19(25-21)27-12-4-10-23-27)26-13-8-17(9-14-26)16-5-2-1-3-6-16/h1-6,10,12,15,17H,7-9,11,13-14H2,(H,28,29)(H,22,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	750	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140571 (CHEMBL3752294) Show SMILES OC(=O)CCNc1nc(cc(n1)-c1nccs1)N1CCN(CC1)c1ccccn1 Show InChI InChI=1S/C19H21N7O2S/c27-17(28)4-6-22-19-23-14(18-21-7-12-29-18)13-16(24-19)26-10-8-25(9-11-26)15-3-1-2-5-20-15/h1-3,5,7,12-13H,4,6,8-11H2,(H,27,28)(H,22,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140573 (CHEMBL3752343) Show SMILES OC(=O)CCNc1nc(cc(n1)-c1nccs1)N1CCN(CC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C20H20Cl2N6O2S/c21-14-2-1-13(11-15(14)22)27-6-8-28(9-7-27)17-12-16(19-23-5-10-31-19)25-20(26-17)24-4-3-18(29)30/h1-2,5,10-12H,3-4,6-9H2,(H,29,30)(H,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	940	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140572 (CHEMBL3753199) Show SMILES OC(=O)CCNc1nc(cc(n1)-c1nccs1)N1CCc2ccccc2C1 Show InChI InChI=1S/C19H19N5O2S/c25-17(26)5-7-21-19-22-15(18-20-8-10-27-18)11-16(23-19)24-9-6-13-3-1-2-4-14(13)12-24/h1-4,8,10-11H,5-7,9,12H2,(H,25,26)(H,21,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	990	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140577 (CHEMBL3753326) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1cccn1)N1CCN(CC1)c1ccccn1 Show InChI InChI=1S/C19H22N8O2/c28-18(29)5-8-21-19-23-16(14-17(24-19)27-9-3-7-22-27)26-12-10-25(11-13-26)15-4-1-2-6-20-15/h1-4,6-7,9,14H,5,8,10-13H2,(H,28,29)(H,21,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140568 (CHEMBL3754078) Show SMILES OC(=O)CCNc1nc(cc(n1)-c1nccs1)N1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C21H23N5O2S/c27-19(28)6-9-23-21-24-17(20-22-10-13-29-20)14-18(25-21)26-11-7-16(8-12-26)15-4-2-1-3-5-15/h1-5,10,13-14,16H,6-9,11-12H2,(H,27,28)(H,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140684 (CHEMBL3753893) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1nccn1)N1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C20H23N7O2/c28-19(29)6-9-21-20-24-17(14-18(25-20)27-22-10-11-23-27)26-12-7-16(8-13-26)15-4-2-1-3-5-15/h1-5,10-11,14,16H,6-9,12-13H2,(H,28,29)(H,21,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140682 (CHEMBL3752967) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1nccn1)N1CCN(CC1)c1ccccn1 Show InChI InChI=1S/C18H21N9O2/c28-17(29)4-6-20-18-23-15(13-16(24-18)27-21-7-8-22-27)26-11-9-25(10-12-26)14-3-1-2-5-19-14/h1-3,5,7-8,13H,4,6,9-12H2,(H,28,29)(H,20,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140683 (CHEMBL3752156) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1nccn1)N1CCN(CC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C19H20Cl2N8O2/c20-14-2-1-13(11-15(14)21)27-7-9-28(10-8-27)16-12-17(29-23-5-6-24-29)26-19(25-16)22-4-3-18(30)31/h1-2,5-6,11-12H,3-4,7-10H2,(H,30,31)(H,22,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140347 (CHEMBL3753356) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1ccnn1)N1CCc2ccccc2C1 Show InChI InChI=1S/C18H19N7O2/c26-17(27)5-7-19-18-21-15(11-16(22-18)25-10-8-20-23-25)24-9-6-13-3-1-2-4-14(13)12-24/h1-4,8,10-11H,5-7,9,12H2,(H,26,27)(H,19,21,22)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140681 (CHEMBL3753787) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1nccn1)N1CCc2ccccc2C1 Show InChI InChI=1S/C18H19N7O2/c26-17(27)5-7-19-18-22-15(11-16(23-18)25-20-8-9-21-25)24-10-6-13-3-1-2-4-14(13)12-24/h1-4,8-9,11H,5-7,10,12H2,(H,26,27)(H,19,22,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140569 (CHEMBL3752995) Show SMILES COc1ccccc1N1CCN(CC1)c1cc(nc(NCCC(O)=O)n1)-c1nccs1 Show InChI InChI=1S/C21H24N6O3S/c1-30-17-5-3-2-4-16(17)26-9-11-27(12-10-26)18-14-15(20-22-8-13-31-20)24-21(25-18)23-7-6-19(28)29/h2-5,8,13-14H,6-7,9-12H2,1H3,(H,28,29)(H,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140346 (CHEMBL3752006) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1ccnn1)N1CCC(CC1)c1ccccc1 Show InChI InChI=1S/C20H23N7O2/c28-19(29)6-9-21-20-23-17(14-18(24-20)27-13-10-22-25-27)26-11-7-16(8-12-26)15-4-2-1-3-5-15/h1-5,10,13-14,16H,6-9,11-12H2,(H,28,29)(H,21,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140349 (CHEMBL3754555) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1cc2ccccc2n1)N1CCc2ccccc2CC1 Show InChI InChI=1S/C24H24N6O2/c31-23(32)9-12-25-24-26-21(29-13-10-17-5-1-2-6-18(17)11-14-29)15-22(27-24)30-16-19-7-3-4-8-20(19)28-30/h1-8,15-16H,9-14H2,(H,31,32)(H,25,26,27)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140685 (CHEMBL3753303) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1nccn1)N1CCN(CC1)c1ccc(F)cc1 Show InChI InChI=1S/C19H21FN8O2/c20-14-1-3-15(4-2-14)26-9-11-27(12-10-26)16-13-17(28-22-7-8-23-28)25-19(24-16)21-6-5-18(29)30/h1-4,7-8,13H,5-6,9-12H2,(H,29,30)(H,21,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140350 (CHEMBL3754777) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1cc2ccccc2n1)N1CCN(CC1)c1ccc(F)cc1 Show InChI InChI=1S/C24H24FN7O2/c25-18-5-7-19(8-6-18)30-11-13-31(14-12-30)21-15-22(28-24(27-21)26-10-9-23(33)34)32-16-17-3-1-2-4-20(17)29-32/h1-8,15-16H,9-14H2,(H,33,34)(H,26,27,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140566 (CHEMBL3754383) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1cc2ccccc2n1)N1CCc2ccccc2C1 Show InChI InChI=1S/C23H22N6O2/c30-22(31)9-11-24-23-25-20(28-12-10-16-5-1-2-6-17(16)14-28)13-21(26-23)29-15-18-7-3-4-8-19(18)27-29/h1-8,13,15H,9-12,14H2,(H,30,31)(H,24,25,26)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140348 (CHEMBL3754052) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1ccnn1)N1CCN(CC1)c1ccc(F)cc1 Show InChI InChI=1S/C19H21FN8O2/c20-14-1-3-15(4-2-14)26-9-11-27(12-10-26)16-13-17(28-8-7-22-25-28)24-19(23-16)21-6-5-18(29)30/h1-4,7-8,13H,5-6,9-12H2,(H,29,30)(H,21,23,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140679 (CHEMBL3752327) Show SMILES COc1ccccc1N1CCN(CC1)c1cc(nc(NCCC(O)=O)n1)-n1cccn1 Show InChI InChI=1S/C21H25N7O3/c1-31-17-6-3-2-5-16(17)26-11-13-27(14-12-26)18-15-19(28-10-4-8-23-28)25-21(24-18)22-9-7-20(29)30/h2-6,8,10,15H,7,9,11-14H2,1H3,(H,29,30)(H,22,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140344 (CHEMBL3753122) Show SMILES COc1ccccc1N1CCN(CC1)c1cc(nc(NCCC(O)=O)n1)-n1nccn1 Show InChI InChI=1S/C20H24N8O3/c1-31-16-5-3-2-4-15(16)26-10-12-27(13-11-26)17-14-18(28-22-8-9-23-28)25-20(24-17)21-7-6-19(29)30/h2-5,8-9,14H,6-7,10-13H2,1H3,(H,29,30)(H,21,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair
Lysine-specific demethylase 6B (Homo sapiens (Human))	BDBM50140351 (CHEMBL3752471) Show SMILES OC(=O)CCNc1nc(cc(n1)-n1cc2ccccc2n1)N1CCN(CC1)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C24H23Cl2N7O2/c25-18-6-5-17(13-19(18)26)31-9-11-32(12-10-31)21-14-22(29-24(28-21)27-8-7-23(34)35)33-15-16-3-1-2-4-20(16)30-33/h1-6,13-15H,7-12H2,(H,34,35)(H,27,28,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of JMJD3 (unknown origin) using biotinylated H3K27me3 peptide as substrate after 1 hr by AlphaLISA assay				Bioorg Med Chem Lett 26: 721-5 (2016) Article DOI: 10.1016/j.bmcl.2016.01.006 BindingDB Entry DOI: 10.7270/Q2P55QC2
					More data for this Ligand-Target Pair