Compile Data Set for Download or QSAR

Found 48 hits Enz. Inhib. hit(s) with all data for entry = 50046937   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50140291 (CHEMBL3758455) Show SMILES Ic1cccc(c1)C1=NCCCC1 |t:8| Show InChI InChI=1S/C11H12IN/c12-10-5-3-4-9(8-10)11-6-1-2-7-13-11/h3-5,8H,1-2,6-7H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50140291 (CHEMBL3758455) Show SMILES Ic1cccc(c1)C1=NCCCC1 |t:8| Show InChI InChI=1S/C11H12IN/c12-10-5-3-4-9(8-10)11-6-1-2-7-13-11/h3-5,8H,1-2,6-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50143314 ((+)-Epibatidine | (-)-epibatidine | (1R,2R,4S)-2-(...) Show SMILES Clc1ccc(cn1)[C@H]1C[C@@H]2CC[C@H]1N2 |THB:4:7:13:11.10| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2/t8-,9+,10+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair				3D Structure (crystal)
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50143314 ((+)-Epibatidine | (-)-epibatidine | (1R,2R,4S)-2-(...) Show SMILES Clc1ccc(cn1)[C@H]1C[C@@H]2CC[C@H]1N2 |THB:4:7:13:11.10| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2/t8-,9+,10+/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I] alpha bungarotoxin from human alpha7 nACh receptor incubated for 20 secs				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair				3D Structure (crystal)
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50140289 (CHEMBL3759225) Show SMILES Brc1cccc(c1)C1=NCCCC1 |t:8| Show InChI InChI=1S/C11H12BrN/c12-10-5-3-4-9(8-10)11-6-1-2-7-13-11/h3-5,8H,1-2,6-7H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM109773 (US8609708, 74 Anabaseine) Show SMILES C1CCC(=NC1)c1cccnc1 |c:3| Show InChI InChI=1S/C10H12N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h3-4,6,8H,1-2,5,7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50140289 (CHEMBL3759225) Show SMILES Brc1cccc(c1)C1=NCCCC1 |t:8| Show InChI InChI=1S/C11H12BrN/c12-10-5-3-4-9(8-10)11-6-1-2-7-13-11/h3-5,8H,1-2,6-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50140303 (CHEMBL3759863) Show SMILES Fc1cc(Br)cc(c1)C1=NCCCC1 |t:9| Show InChI InChI=1S/C11H11BrFN/c12-9-5-8(6-10(13)7-9)11-3-1-2-4-14-11/h5-7H,1-4H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	48	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM109773 (US8609708, 74 Anabaseine) Show SMILES C1CCC(=NC1)c1cccnc1 |c:3| Show InChI InChI=1S/C10H12N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h3-4,6,8H,1-2,5,7H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50140292 (CHEMBL3759852) Show SMILES Brc1cc(Br)cc(c1)C1=NCCCC1 |t:9| Show InChI InChI=1S/C11H11Br2N/c12-9-5-8(6-10(13)7-9)11-3-1-2-4-14-11/h5-7H,1-4H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50140288 (CHEMBL3759731) Show SMILES Clc1cccc(c1)C1=NCCCC1 |t:8| Show InChI InChI=1S/C11H12ClN/c12-10-5-3-4-9(8-10)11-6-1-2-7-13-11/h3-5,8H,1-2,6-7H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50139124 (CHEMBL3759208) Show SMILES OCc1cccc(c1)C1=NCCCC1 |t:9| Show InChI InChI=1S/C12H15NO/c14-9-10-4-3-5-11(8-10)12-6-1-2-7-13-12/h3-5,8,14H,1-2,6-7,9H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50139125 (CHEMBL3760021) Show SMILES [H][C@@]12CC[C@@]([H])(N1)[C@H](C2)c1cccc(O)c1 |r| Show InChI InChI=1S/C12H15NO/c14-10-3-1-2-8(6-10)11-7-9-4-5-12(11)13-9/h1-3,6,9,11-14H,4-5,7H2/t9-,11+,12+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50142626 (CHEMBL3758480) Show SMILES OCc1cc(F)cc(c1)C1=NCCCC1 |t:10| Show InChI InChI=1S/C12H14FNO/c13-11-6-9(8-15)5-10(7-11)12-3-1-2-4-14-12/h5-7,15H,1-4,8H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50142625 (CHEMBL3758513) Show SMILES [H][C@@]12CC[C@@]([H])(N1)[C@H](C2)c1cccc(CO)c1 |r| Show InChI InChI=1S/C13H17NO/c15-8-9-2-1-3-10(6-9)12-7-11-4-5-13(12)14-11/h1-3,6,11-15H,4-5,7-8H2/t11-,12+,13+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM109773 (US8609708, 74 Anabaseine) Show SMILES C1CCC(=NC1)c1cccnc1 |c:3| Show InChI InChI=1S/C10H12N2/c1-2-7-12-10(5-1)9-4-3-6-11-8-9/h3-4,6,8H,1-2,5,7H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase MCE KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	107	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50140287 (CHEMBL3758648) Show SMILES Fc1cccc(c1)C1=NCCCC1 |t:8| Show InChI InChI=1S/C11H12FN/c12-10-5-3-4-9(8-10)11-6-1-2-7-13-11/h3-5,8H,1-2,6-7H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	108	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50139125 (CHEMBL3760021) Show SMILES [H][C@@]12CC[C@@]([H])(N1)[C@H](C2)c1cccc(O)c1 |r| Show InChI InChI=1S/C12H15NO/c14-10-3-1-2-8(6-10)11-7-9-4-5-12(11)13-9/h1-3,6,9,11-14H,4-5,7H2/t9-,11+,12+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	127	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50142623 (CHEMBL3758565) Show SMILES Cc1cccc(c1)C1=NCCCC1 |t:8| Show InChI InChI=1S/C12H15N/c1-10-5-4-6-11(9-10)12-7-2-3-8-13-12/h4-6,9H,2-3,7-8H2,1H3	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	155	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50139124 (CHEMBL3759208) Show SMILES OCc1cccc(c1)C1=NCCCC1 |t:9| Show InChI InChI=1S/C12H15NO/c14-9-10-4-3-5-11(8-10)12-6-1-2-7-13-12/h3-5,8,14H,1-2,6-7,9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	158	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50142624 (CHEMBL3759403) Show SMILES C1CCC(=NC1)c1ccccc1 |c:3| Show InChI InChI=1S/C11H13N/c1-2-6-10(7-3-1)11-8-4-5-9-12-11/h1-3,6-7H,4-5,8-9H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	194	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50140303 (CHEMBL3759863) Show SMILES Fc1cc(Br)cc(c1)C1=NCCCC1 |t:9| Show InChI InChI=1S/C11H11BrFN/c12-9-5-8(6-10(13)7-9)11-3-1-2-4-14-11/h5-7H,1-4H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	204	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50140292 (CHEMBL3759852) Show SMILES Brc1cc(Br)cc(c1)C1=NCCCC1 |t:9| Show InChI InChI=1S/C11H11Br2N/c12-9-5-8(6-10(13)7-9)11-3-1-2-4-14-11/h5-7H,1-4H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	343	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50142623 (CHEMBL3758565) Show SMILES Cc1cccc(c1)C1=NCCCC1 |t:8| Show InChI InChI=1S/C12H15N/c1-10-5-4-6-11(9-10)12-7-2-3-8-13-12/h4-6,9H,2-3,7-8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	384	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50140288 (CHEMBL3759731) Show SMILES Clc1cccc(c1)C1=NCCCC1 |t:8| Show InChI InChI=1S/C11H12ClN/c12-10-5-3-4-9(8-10)11-6-1-2-7-13-11/h3-5,8H,1-2,6-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	394	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50142625 (CHEMBL3758513) Show SMILES [H][C@@]12CC[C@@]([H])(N1)[C@H](C2)c1cccc(CO)c1 |r| Show InChI InChI=1S/C13H17NO/c15-8-9-2-1-3-10(6-9)12-7-11-4-5-13(12)14-11/h1-3,6,11-15H,4-5,7-8H2/t11-,12+,13+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	429	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50139125 (CHEMBL3760021) Show SMILES [H][C@@]12CC[C@@]([H])(N1)[C@H](C2)c1cccc(O)c1 |r| Show InChI InChI=1S/C12H15NO/c14-10-3-1-2-8(6-10)11-7-9-4-5-12(11)13-9/h1-3,6,9,11-14H,4-5,7H2/t9-,11+,12+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	609	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50142627 (CHEMBL3758367) Show SMILES Oc1cccc(c1)C1=NCCCC1 |t:8| Show InChI InChI=1S/C11H13NO/c13-10-5-3-4-9(8-10)11-6-1-2-7-12-11/h3-5,8,13H,1-2,6-7H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	680	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from human alpha3beta4 nACh receptor expressed in HEK293 cells preincubated for 5 mins followed by radioligand addit...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50142626 (CHEMBL3758480) Show SMILES OCc1cc(F)cc(c1)C1=NCCCC1 |t:10| Show InChI InChI=1S/C12H14FNO/c13-11-6-9(8-15)5-10(7-11)12-3-1-2-4-14-12/h5-7,15H,1-4,8H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	744	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50142626 (CHEMBL3758480) Show SMILES OCc1cc(F)cc(c1)C1=NCCCC1 |t:10| Show InChI InChI=1S/C12H14FNO/c13-11-6-9(8-15)5-10(7-11)12-3-1-2-4-14-12/h5-7,15H,1-4,8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	821	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50142623 (CHEMBL3758565) Show SMILES Cc1cccc(c1)C1=NCCCC1 |t:8| Show InChI InChI=1S/C12H15N/c1-10-5-4-6-11(9-10)12-7-2-3-8-13-12/h4-6,9H,2-3,7-8H2,1H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.45E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50140303 (CHEMBL3759863) Show SMILES Fc1cc(Br)cc(c1)C1=NCCCC1 |t:9| Show InChI InChI=1S/C11H11BrFN/c12-9-5-8(6-10(13)7-9)11-3-1-2-4-14-11/h5-7H,1-4H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.77E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50142625 (CHEMBL3758513) Show SMILES [H][C@@]12CC[C@@]([H])(N1)[C@H](C2)c1cccc(CO)c1 |r| Show InChI InChI=1S/C13H17NO/c15-8-9-2-1-3-10(6-9)12-7-11-4-5-13(12)14-11/h1-3,6,11-15H,4-5,7-8H2/t11-,12+,13+/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50140287 (CHEMBL3758648) Show SMILES Fc1cccc(c1)C1=NCCCC1 |t:8| Show InChI InChI=1S/C11H12FN/c12-10-5-3-4-9(8-10)11-6-1-2-7-13-11/h3-5,8H,1-2,6-7H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.04E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50142624 (CHEMBL3759403) Show SMILES C1CCC(=NC1)c1ccccc1 |c:3| Show InChI InChI=1S/C11H13N/c1-2-6-10(7-3-1)11-8-4-5-9-12-11/h1-3,6-7H,4-5,8-9H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.08E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50140287 (CHEMBL3758648) Show SMILES Fc1cccc(c1)C1=NCCCC1 |t:8| Show InChI InChI=1S/C11H12FN/c12-10-5-3-4-9(8-10)11-6-1-2-7-13-11/h3-5,8H,1-2,6-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.37E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50142624 (CHEMBL3759403) Show SMILES C1CCC(=NC1)c1ccccc1 |c:3| Show InChI InChI=1S/C11H13N/c1-2-6-10(7-3-1)11-8-4-5-9-12-11/h1-3,6-7H,4-5,8-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50140291 (CHEMBL3758455) Show SMILES Ic1cccc(c1)C1=NCCCC1 |t:8| Show InChI InChI=1S/C11H12IN/c12-10-5-3-4-9(8-10)11-6-1-2-7-13-11/h3-5,8H,1-2,6-7H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.79E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50140289 (CHEMBL3759225) Show SMILES Brc1cccc(c1)C1=NCCCC1 |t:8| Show InChI InChI=1S/C11H12BrN/c12-10-5-3-4-9(8-10)11-6-1-2-7-13-11/h3-5,8H,1-2,6-7H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50142627 (CHEMBL3758367) Show SMILES Oc1cccc(c1)C1=NCCCC1 |t:8| Show InChI InChI=1S/C11H13NO/c13-10-5-3-4-9(8-10)11-6-1-2-7-12-11/h3-5,8,13H,1-2,6-7H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	9.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [125I] alpha bungarotoxin from rat alpha7 nACh receptor expressed in rat hippocampal membrane preincubated for 30 mins followed by ra...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50140288 (CHEMBL3759731) Show SMILES Clc1cccc(c1)C1=NCCCC1 |t:8| Show InChI InChI=1S/C11H12ClN/c12-10-5-3-4-9(8-10)11-6-1-2-7-13-11/h3-5,8H,1-2,6-7H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.15E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50140292 (CHEMBL3759852) Show SMILES Brc1cc(Br)cc(c1)C1=NCCCC1 |t:9| Show InChI InChI=1S/C11H11Br2N/c12-9-5-8(6-10(13)7-9)11-3-1-2-4-14-11/h5-7H,1-4H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.88E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50142627 (CHEMBL3758367) Show SMILES Oc1cccc(c1)C1=NCCCC1 |t:8| Show InChI InChI=1S/C11H13NO/c13-10-5-3-4-9(8-10)11-6-1-2-7-12-11/h3-5,8,13H,1-2,6-7H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.20E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Rattus norvegicus (Rat))	BDBM50139124 (CHEMBL3759208) Show SMILES OCc1cccc(c1)C1=NCCCC1 |t:9| Show InChI InChI=1S/C12H15NO/c14-9-10-4-3-5-11(8-10)12-6-1-2-7-13-12/h3-5,8,14H,1-2,6-7,9H2	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Displacement of [3H]-epibatidine from rat alpha4beta2 nACh receptor expressed in rat cortical membrane preincubated for 30 mins followed by radioliga...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50143314 ((+)-Epibatidine | (-)-epibatidine | (1R,2R,4S)-2-(...) Show SMILES Clc1ccc(cn1)[C@H]1C[C@@H]2CC[C@H]1N2 |THB:4:7:13:11.10| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2/t8-,9+,10+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Binding affinity to alpha3beta4 nACh receptor (unknown origin) expressed in Xenopus oocytes				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50139124 (CHEMBL3759208) Show SMILES OCc1cccc(c1)C1=NCCCC1 |t:9| Show InChI InChI=1S/C12H15NO/c14-9-10-4-3-5-11(8-10)12-6-1-2-7-13-12/h3-5,8,14H,1-2,6-7,9H2	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	6.00E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Agonist activity at human alpha7 nACh receptor expressed in rat GH4C1 cells assessed as increase in current amplitudes after 2 to 3 days by patch cla...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-3/beta-4 (Homo sapiens (Human))	BDBM50139124 (CHEMBL3759208) Show SMILES OCc1cccc(c1)C1=NCCCC1 |t:9| Show InChI InChI=1S/C12H15NO/c14-9-10-4-3-5-11(8-10)12-6-1-2-7-13-12/h3-5,8,14H,1-2,6-7,9H2	PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Agonist activity at human alpha3beta4 nACh receptor expressed in rat GH4C1 cells assessed as increase in current amplitudes after 2 to 3 days by patc...				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-4/beta-2 (Homo sapiens (Human))	BDBM50143314 ((+)-Epibatidine | (-)-epibatidine | (1R,2R,4S)-2-(...) Show SMILES Clc1ccc(cn1)[C@H]1C[C@@H]2CC[C@H]1N2 |THB:4:7:13:11.10| Show InChI InChI=1S/C11H13ClN2/c12-11-4-1-7(6-13-11)9-5-8-2-3-10(9)14-8/h1,4,6,8-10,14H,2-3,5H2/t8-,9+,10+/m0/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	0.0300	n/a	n/a	n/a	n/a	n/a
Universit£ degli Studi di Milano Curated by ChEMBL					Assay Description Binding affinity to alpha4beta2 nACh receptor (unknown origin) expressed in Xenopus oocytes				Eur J Med Chem 108: 392-405 (2016) Article DOI: 10.1016/j.ejmech.2015.11.045 BindingDB Entry DOI: 10.7270/Q2ZS2ZCH
					More data for this Ligand-Target Pair