Found 6 hits Enz. Inhib. hit(s) with all data for entry = 50029406 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Carnitine O-palmitoyltransferase 1, liver isoform
(Rattus norvegicus) | BDBM50284163
((S)-4-Hexadecyl-2,6,6-trimethyl-2-oxo-2lambda*5*-[...)Show SMILES CCCCCCCCCCCCCCCCC1C[N+](C)(C)CCO[P@](C)(=O)O1 Show InChI InChI=1S/C23H49NO3P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23-22-24(2,3)20-21-26-28(4,25)27-23/h23H,5-22H2,1-4H3/q+1/t23?,28-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 1.28E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibitory potency of the compound against Carnitine Palmitoyltransferase (CPT-II) |
Bioorg Med Chem Lett 4: 883-886 (1994)
Article DOI: 10.1016/S0960-894X(01)80256-0 BindingDB Entry DOI: 10.7270/Q2RX9C15 |
More data for this Ligand-Target Pair | |
Carnitine O-palmitoyltransferase 2, mitochondrial
(Homo sapiens (Human)) | BDBM50284164
((S)-2-Hexadecyl-2-hydroxy-4,4-dimethyl-morpholin-4...)Show InChI InChI=1S/C22H46NO2/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(24)21-23(2,3)19-20-25-22/h24H,4-21H2,1-3H3/q+1/t22-/m0/s1 | Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 2.35E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibitory potency of the compound against Carnitine Palmitoyltransferase (CPT-II); Range = 32-235 microM |
Bioorg Med Chem Lett 4: 883-886 (1994)
Article DOI: 10.1016/S0960-894X(01)80256-0 BindingDB Entry DOI: 10.7270/Q2RX9C15 |
More data for this Ligand-Target Pair | |
Carnitine O-palmitoyltransferase 1, liver isoform
(Rattus norvegicus) | BDBM50284163
((S)-4-Hexadecyl-2,6,6-trimethyl-2-oxo-2lambda*5*-[...)Show SMILES CCCCCCCCCCCCCCCCC1C[N+](C)(C)CCO[P@](C)(=O)O1 Show InChI InChI=1S/C23H49NO3P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23-22-24(2,3)20-21-26-28(4,25)27-23/h23H,5-22H2,1-4H3/q+1/t23?,28-/m0/s1 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 3.05E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibitory potency of the compound against Carnitine Palmitoyltransferase (CPT-II) |
Bioorg Med Chem Lett 4: 883-886 (1994)
Article DOI: 10.1016/S0960-894X(01)80256-0 BindingDB Entry DOI: 10.7270/Q2RX9C15 |
More data for this Ligand-Target Pair | |
Peroxisomal carnitine O-octanoyltransferase
(Homo sapiens (Human)) | BDBM50284163
((S)-4-Hexadecyl-2,6,6-trimethyl-2-oxo-2lambda*5*-[...)Show SMILES CCCCCCCCCCCCCCCCC1C[N+](C)(C)CCO[P@](C)(=O)O1 Show InChI InChI=1S/C23H49NO3P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23-22-24(2,3)20-21-26-28(4,25)27-23/h23H,5-22H2,1-4H3/q+1/t23?,28-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 4.75E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibitory potency of the compound against carnitine octanoyltransferase (COT) |
Bioorg Med Chem Lett 4: 883-886 (1994)
Article DOI: 10.1016/S0960-894X(01)80256-0 BindingDB Entry DOI: 10.7270/Q2RX9C15 |
More data for this Ligand-Target Pair | |
Peroxisomal carnitine O-octanoyltransferase
(Homo sapiens (Human)) | BDBM50284163
((S)-4-Hexadecyl-2,6,6-trimethyl-2-oxo-2lambda*5*-[...)Show SMILES CCCCCCCCCCCCCCCCC1C[N+](C)(C)CCO[P@](C)(=O)O1 Show InChI InChI=1S/C23H49NO3P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23-22-24(2,3)20-21-26-28(4,25)27-23/h23H,5-22H2,1-4H3/q+1/t23?,28-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article
| n/a | n/a | 9.12E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibitory potency of the compound against carnitine octanoyltransferase (COT) |
Bioorg Med Chem Lett 4: 883-886 (1994)
Article DOI: 10.1016/S0960-894X(01)80256-0 BindingDB Entry DOI: 10.7270/Q2RX9C15 |
More data for this Ligand-Target Pair | |
Peroxisomal carnitine O-octanoyltransferase
(Homo sapiens (Human)) | BDBM50284164
((S)-2-Hexadecyl-2-hydroxy-4,4-dimethyl-morpholin-4...)Show InChI InChI=1S/C22H46NO2/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22(24)21-23(2,3)19-20-25-22/h24H,4-21H2,1-3H3/q+1/t22-/m0/s1 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 4.00E+6 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
Curated by ChEMBL
| Assay Description Inhibitory potency of the compound against carnitine octanoyltransferase (COT); Range = 1300-4000 microM |
Bioorg Med Chem Lett 4: 883-886 (1994)
Article DOI: 10.1016/S0960-894X(01)80256-0 BindingDB Entry DOI: 10.7270/Q2RX9C15 |
More data for this Ligand-Target Pair | |