BindingDB PrimarySearch

Found 42 hits Enz. Inhib. hit(s) with all data for entry = 50047159
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Melatonin receptor type 1A (Homo sapiens (Human))	BDBM50114703 (CHEMBL287560 \| N-[2-(5-Methoxy-2-phenyl-benzofuran...) Show SMILES COc1ccc2oc(c(CCNC(C)=O)c2c1)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Melatonin receptor type 1B (Homo sapiens (Human))	BDBM50114703 (CHEMBL287560 \| N-[2-(5-Methoxy-2-phenyl-benzofuran...) Show SMILES COc1ccc2oc(c(CCNC(C)=O)c2c1)-c1ccccc1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Melatonin receptor type 1B (Homo sapiens (Human))	BDBM50114716 (CHEMBL329263 \| N-[2-(2-Benzyl-5-methoxy-benzofuran...) Show SMILES COc1ccc2oc(Cc3ccccc3)c(CCNC(C)=O)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.0500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM21367 (6-{4-[2-(methylsulfanyl)phenyl]piperazin-1-yl}-N-(...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	0.220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50367061 (NALORPHINE \| NALORPHINE HYDROCHLORIDE) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	0.360	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50150945 (CHEBI:81390 \| Immepip) Show SMILES C(C1CCNCC1)c1c[nH]cn1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid PDB UniChem Similars	Article PubMed	0.479	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM50000092 ((-)-(etorphine) \| (-)-morphine \| (1S,5R,13R,14S)-1...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	0.530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50199326 (CHEMBL217673 \| N-butyloxycarbonyl-2-(4-imidazol-1-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.700	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Melatonin receptor type 1A (Homo sapiens (Human))	BDBM50114716 (CHEMBL329263 \| N-[2-(2-Benzyl-5-methoxy-benzofuran...) Show SMILES COc1ccc2oc(Cc3ccccc3)c(CCNC(C)=O)c2c1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50147740 (1-(1-Cyclooctyl-piperidin-4-yl)-1,3-dihydro-indol-...) Show SMILES O=C1Cc2ccccc2N1C1CCN(CC1)C1CCCCCCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM21221 ((2S,3S,4R,5R)-5-(2-chloro-6-{[(3-iodophenyl)methyl...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50049195 (3-[(2'-(butylsulfonylcarbamate)-3'-propyl-1,1'-bip...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50088421 ((2R,3R,4S,5R)-2-[2-Chloro-6-(3-iodo-benzylamino)-p...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50118812 ((2S,3S,4R,5R)-3,4-Dihydroxy-5-[6-(3-iodo-benzylami...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory activity against Beta-glucosidase from Yeast				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50138301 (4-[(S)-4-(4-{2-[1-(Acetyl-ethyl-amino)-ethyl]-phen...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50367061 (NALORPHINE \| NALORPHINE HYDROCHLORIDE) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase KEGG PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50141059 (CHEMBL289614 \| L-162782 \| N-Butyloxycarbonyl-4'-(2...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50118336 (1-(5-Fluoro-benzo[b]thiophen-3-yl)-3-(4-quinolin-8...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory activity against Beta-glucosidase from Yeast				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50409817 (CHEMBL78498 \| VUF-5681) Show SMILES C(CC1CCNCC1)Cc1cnc[nH]1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50088422 ((2R,3R,4S,5R)-2-(6-(3-iodobenzylamino)-9H-purin-9-...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Rattus norvegicus (rat))	BDBM50118335 (3-(4-(2,3-dihydrobenzo[b][1,4]dioxin-5-yl)piperazi...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory activity against Beta-glucosidase from Almond				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50147749 (1-(1-Cyclooctylmethyl-piperidin-4-yl)-1,3-dihydro-...) Show SMILES O=C1Cc2ccccc2N1C1CCN(CC2CCCCCCC2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Melanocortin receptor 4 (Homo sapiens (Human))	BDBM50138296 ((S)-4-(4-{2-[1-(Acetyl-ethyl-amino)-ethyl]-phenyl}...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM21368 (6-[4-(2-methoxyphenyl)piperazin-1-yl]-N-(1,2,3,4-t...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50150942 (CHEMBL3394209) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM21371 (6-[4-(2-hydroxyphenyl)piperazin-1-yl]-N-(1,2,3,4-t...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Type-2 angiotensin II receptor (Homo sapiens (Human))	BDBM50145197 (CHEMBL3394207) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Rattus norvegicus (rat))	BDBM21369 (6-[4-(2-methylphenyl)piperazin-1-yl]-N-(1,2,3,4-te...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50409216 (CHEMBL150701) Show SMILES C(Cc1cnc[nH]1)C1CCNCC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50150941 (CHEMBL2181969 \| MRS-1292) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory activity against Beta-glucosidase from Almond				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM50085658 ((2R,3R,4S,5R)-2-(2-Chloro-6-cyclopentylamino-purin...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	38	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory activity against Beta-glucosidase from Almond				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM181143 (US9138393, Immepip dihydrobromide \| US9144538, Imm...) Show SMILES C(C1CCCNC1)c1c[nH]cn1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	68	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Adenosine receptor A3 (Homo sapiens (Human))	BDBM25400 ((2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-y...) Show SMILES Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	72	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibitory activity against Beta-glucosidase from E-coli				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50150943 (CHEMBL154529) Show SMILES C(CC1CCCNC1)Cc1c[nH]cn1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	83	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM50000092 ((-)-(etorphine) \| (-)-morphine \| (1S,5R,13R,14S)-1...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Histamine H3 receptor (Homo sapiens (Human))	BDBM50150944 (CHEMBL153207) Show SMILES C(Cc1c[nH]cn1)C1CCCNC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	182	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM50147746 (1-(1-Benzyl-piperidin-4-yl)-1,3-dihydro-indol-2-on...) Show SMILES O=C1Cc2ccccc2N1C1CCN(Cc2ccccc2)CC1 Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	201	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Homo sapiens (Human))	BDBM50150940 (CHEMBL3774617) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Homo sapiens (Human))	BDBM50146899 (4-((E)-2-{[({2,4-Dichloro-3-[2-methyl-4-(pyridin-2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.410	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Homo sapiens (Human))	BDBM50067281 (4-{(E)-2-[({[2,4-Dichloro-3-(2-methyl-quinolin-8-y...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
Vasopressin V2 receptor (Homo sapiens (Human))	BDBM50094079 ((4-Amino-2-methyl-phenyl)-(7-chloro-2,3,4,5-tetrah...) Show SMILES Cc1cc(N)ccc1C(=O)N1CCCCc2cc(Cl)ccc12 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair
B2 bradykinin receptor (Homo sapiens (Human))	BDBM50146893 (4-{(E)-2-[({[2,4-Dichloro-3-(4-ethoxy-2-methyl-qui...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
University of Minnesota Curated by ChEMBL					Assay Description Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...				J Med Chem 59: 810-40 (2016) Article DOI: 10.1021/acs.jmedchem.5b00982 BindingDB Entry DOI: 10.7270/Q2XS5X8K
University of Minnesota Curated by ChEMBL					More data for this Ligand-Target Pair