Compile Data Set for Download or QSAR

Found 21 hits Enz. Inhib. hit(s) with all data for entry = 50029794   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
GTPase HRas (Homo sapiens (Human))	BDBM50287960 (1-[(2R,6S)-6-(tert-Butyl-dimethyl-silanyloxymethyl...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@@H](CO[Si](C)(C)C(C)(C)C)O1)Sc1ccccc1[N+]([O-])=O Show InChI InChI=1S/C29H36ClN5O5SSi/c1-18-26-27(30)21-14-19(38-5)12-13-22(21)31-28(26)34(32-18)25-16-33(41-24-11-9-8-10-23(24)35(36)37)15-20(40-25)17-39-42(6,7)29(2,3)4/h8-14,20,25H,15-17H2,1-7H3/t20-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287951 (3-[(3aS,4R,6R,6aR)-6-(4-Chloro-6-methoxy-3-methyl-...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@@H]1O[C@H](OC(O)CC(=O)c2ccccc2)[C@H]2OC(=S)O[C@@H]12 Show InChI InChI=1S/C26H22ClN3O7S/c1-12-19-20(27)15-10-14(33-2)8-9-16(15)28-23(19)30(29-12)24-21-22(36-26(38)35-21)25(37-24)34-18(32)11-17(31)13-6-4-3-5-7-13/h3-10,18,21-22,24-25,32H,11H2,1-2H3/t18?,21-,22+,24-,25+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid UniChem Similars	Article	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287961 ((E)-5-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@H](O1)C=CCC(C)=O)Sc1ccc(cc1)[N+]([O-])=O |w:24.28| Show InChI InChI=1S/C27H26ClN5O5S/c1-16(34)5-4-6-20-14-31(39-21-10-7-18(8-11-21)33(35)36)15-24(38-20)32-27-25(17(2)30-32)26(28)22-13-19(37-3)9-12-23(22)29-27/h4,6-13,20,24H,5,14-15H2,1-3H3/t20-,24-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287943 ((E)-4-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@H](O1)C=CCC(=O)c1ccccc1)Sc1ccccc1[N+]([O-])=O |w:24.28| Show InChI InChI=1S/C32H28ClN5O5S/c1-20-30-31(33)24-17-22(42-2)15-16-25(24)34-32(30)37(35-20)29-19-36(44-28-14-7-6-12-26(28)38(40)41)18-23(43-29)11-8-13-27(39)21-9-4-3-5-10-21/h3-12,14-17,23,29H,13,18-19H2,1-2H3/t23-,29-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	4.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287946 (1-[(2R,6S)-6-(tert-Butyl-dimethyl-silanyloxymethyl...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@@H](CO[Si](C)(C)C(C)(C)C)O1)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C29H36ClN5O7SSi/c1-18-26-27(30)23-14-20(40-5)10-13-24(23)31-28(26)34(32-18)25-16-33(15-21(42-25)17-41-44(6,7)29(2,3)4)43(38,39)22-11-8-19(9-12-22)35(36)37/h8-14,21,25H,15-17H2,1-7H3/t21-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287963 (CHEMBL300769 | [(2S,6R)-6-(4-Chloro-6-methoxy-3-me...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@@H](CO)O1)Sc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C23H22ClN5O5S/c1-13-21-22(24)18-9-15(33-2)5-8-19(18)25-23(21)28(26-13)20-11-27(10-16(12-30)34-20)35-17-6-3-14(4-7-17)29(31)32/h3-9,16,20,30H,10-12H2,1-2H3/t16-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	6.70E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287959 ((E)-4-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@H](O1)C=CCC(=O)c1ccccc1)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O |w:24.28| Show InChI InChI=1S/C32H28ClN5O7S/c1-20-30-31(33)26-17-23(44-2)13-16-27(26)34-32(30)37(35-20)29-19-36(46(42,43)25-14-11-22(12-15-25)38(40)41)18-24(45-29)9-6-10-28(39)21-7-4-3-5-8-21/h3-9,11-17,24,29H,10,18-19H2,1-2H3/t24-,29-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	7.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287955 ((E)-4-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@H](O1)C=CCC(=O)c1ccccc1)Sc1ccc(cc1)[N+]([O-])=O |w:24.28| Show InChI InChI=1S/C32H28ClN5O5S/c1-20-30-31(33)26-17-23(42-2)13-16-27(26)34-32(30)37(35-20)29-19-36(44-25-14-11-22(12-15-25)38(40)41)18-24(43-29)9-6-10-28(39)21-7-4-3-5-8-21/h3-9,11-17,24,29H,10,18-19H2,1-2H3/t24-,29-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	7.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287958 (CHEMBL303105 | [(2S,6R)-6-(4-Chloro-6-methoxy-3-me...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@@H](CO)O1)S(=O)(=O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C23H22ClN5O7S/c1-13-21-22(24)18-9-15(35-2)5-8-19(18)25-23(21)28(26-13)20-11-27(10-16(12-30)36-20)37(33,34)17-6-3-14(4-7-17)29(31)32/h3-9,16,20,30H,10-12H2,1-2H3/t16-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	8.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287944 ((E)-3-[(2S,3S,4R,5R)-5-(4-Chloro-6-methoxy-3-methy...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@@H]1O[C@H](O\C=C\C(=O)c2ccccc2)[C@@H](O)[C@H]1O Show InChI InChI=1S/C25H22ClN3O6/c1-13-19-20(26)16-12-15(33-2)8-9-17(16)27-23(19)29(28-13)24-21(31)22(32)25(35-24)34-11-10-18(30)14-6-4-3-5-7-14/h3-12,21-22,24-25,31-32H,1-2H3/b11-10+/t21-,22+,24-,25+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287945 (5-(4-chloro-6-methoxy-3-methyl-1H-pyrazolo[3,4-b]q...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@@H]1O[C@H](COC(=O)c2ccccc2)[C@@H](OC(=O)c2ccccc2)[C@H]1OC(=O)c1ccccc1 Show InChI InChI=1S/C38H30ClN3O8/c1-22-30-31(39)27-20-26(46-2)18-19-28(27)40-34(30)42(41-22)35-33(50-38(45)25-16-10-5-11-17-25)32(49-37(44)24-14-8-4-9-15-24)29(48-35)21-47-36(43)23-12-6-3-7-13-23/h3-20,29,32-33,35H,21H2,1-2H3/t29-,32-,33-,35-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description In vitro for inhibition of nucleotide exchange process of oncogenic Ras				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287953 (5-(4-chloro-6-methoxy-3-methyl-1H-pyrazolo[3,4-b]q...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@@H]1O[C@H](COC(=O)c2ccco2)[C@@H](OC(=O)c2ccco2)[C@H]1OC(=O)c1ccco1 Show InChI InChI=1S/C32H24ClN3O11/c1-16-24-25(33)18-14-17(40-2)9-10-19(18)34-28(24)36(35-16)29-27(47-32(39)22-8-5-13-43-22)26(46-31(38)21-7-4-12-42-21)23(45-29)15-44-30(37)20-6-3-11-41-20/h3-14,23,26-27,29H,15H2,1-2H3/t23-,26-,27-,29-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.05E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287962 (CHEMBL61870 | [(2S,6R)-4-Benzenesulfonyl-6-(4-chlo...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@@H](CO)O1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C23H23ClN4O5S/c1-14-21-22(24)18-10-15(32-2)8-9-19(18)25-23(21)28(26-14)20-12-27(11-16(13-29)33-20)34(30,31)17-6-4-3-5-7-17/h3-10,16,20,29H,11-13H2,1-2H3/t16-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287949 (1-[(2R,6S)-4-Benzenesulfonyl-6-(tert-butyl-dimethy...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@@H](CO[Si](C)(C)C(C)(C)C)O1)S(=O)(=O)c1ccccc1 Show InChI InChI=1S/C29H37ClN4O5SSi/c1-19-26-27(30)23-15-20(37-5)13-14-24(23)31-28(26)34(32-19)25-17-33(40(35,36)22-11-9-8-10-12-22)16-21(39-25)18-38-41(6,7)29(2,3)4/h8-15,21,25H,16-18H2,1-7H3/t21-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287948 (CHEMBL64886 | [(2S,6R)-6-(4-Chloro-6-methoxy-3-met...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@@H](CO)O1)Sc1ccccc1[N+]([O-])=O Show InChI InChI=1S/C23H22ClN5O5S/c1-13-21-22(24)16-9-14(33-2)7-8-17(16)25-23(21)28(26-13)20-11-27(10-15(12-30)34-20)35-19-6-4-3-5-18(19)29(31)32/h3-9,15,20,30H,10-12H2,1-2H3/t15-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287956 (Benzoic acid (3aR,4R,6R,6aR)-6-(4-chloro-6-methoxy...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@@H]1O[C@H](COC(=O)c2ccccc2)[C@H]2OC(=S)O[C@@H]12 Show InChI InChI=1S/C25H20ClN3O6S/c1-12-18-19(26)15-10-14(31-2)8-9-16(15)27-22(18)29(28-12)23-21-20(34-25(36)35-21)17(33-23)11-32-24(30)13-6-4-3-5-7-13/h3-10,17,20-21,23H,11H2,1-2H3/t17-,20-,21-,23-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287947 ((E)-4-[(2R,6R)-6-(4-Chloro-6-methoxy-3-methyl-pyra...) Show SMILES CCOC(=O)\C=C\C[C@@H]1CN(C[C@@H](O1)n1nc(C)c2c(Cl)c3cc(OC)ccc3nc12)Sc1ccccc1[N+]([O-])=O Show InChI InChI=1S/C28H28ClN5O6S/c1-4-39-25(35)11-7-8-19-15-32(41-23-10-6-5-9-22(23)34(36)37)16-24(40-19)33-28-26(17(2)31-33)27(29)20-14-18(38-3)12-13-21(20)30-28/h5-7,9-14,19,24H,4,8,15-16H2,1-3H3/b11-7+/t19-,24-/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287952 (CHEMBL304717 | N-{4-[(2S,6R)-2-(tert-Butyl-dimethy...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@@H](CO[Si](C)(C)C(C)(C)C)O1)S(=O)(=O)c1ccc(NC(C)=O)cc1 Show InChI InChI=1S/C31H40ClN5O6SSi/c1-19-28-29(32)25-15-22(41-6)11-14-26(25)34-30(28)37(35-19)27-17-36(16-23(43-27)18-42-45(7,8)31(3,4)5)44(39,40)24-12-9-21(10-13-24)33-20(2)38/h9-15,23,27H,16-18H2,1-8H3,(H,33,38)/t23-,27+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287954 ((E)-3-[(2S,5R)-5-(4-Chloro-6-methoxy-3-methyl-pyra...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@@H]1O[C@H](O\C=C\C(=O)c2ccccc2)C=C1 |c:35| Show InChI InChI=1S/C25H20ClN3O4/c1-15-23-24(26)18-14-17(31-2)8-9-19(18)27-25(23)29(28-15)21-10-11-22(33-21)32-13-12-20(30)16-6-4-3-5-7-16/h3-14,21-22H,1-2H3/b13-12+/t21-,22+/m1/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	3.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287957 (1-[(2R,6S)-6-(tert-Butyl-dimethyl-silanyloxymethyl...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@H]1CN(C[C@@H](CO[Si](C)(C)C(C)(C)C)O1)Sc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C29H36ClN5O5SSi/c1-18-26-27(30)23-14-20(38-5)10-13-24(23)31-28(26)34(32-18)25-16-33(41-22-11-8-19(9-12-22)35(36)37)15-21(40-25)17-39-42(6,7)29(2,3)4/h8-14,21,25H,15-17H2,1-7H3/t21-,25+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair
GTPase HRas (Homo sapiens (Human))	BDBM50287950 (Benzoic acid (2S,5R)-5-(4-chloro-6-methoxy-3-methy...) Show SMILES COc1ccc2nc3n(nc(C)c3c(Cl)c2c1)[C@@H]1O[C@H](COC(=O)c2ccccc2)C=C1 |c:34| Show InChI InChI=1S/C24H20ClN3O4/c1-14-21-22(25)18-12-16(30-2)8-10-19(18)26-23(21)28(27-14)20-11-9-17(32-20)13-31-24(29)15-6-4-3-5-7-15/h3-12,17,20H,13H2,1-2H3/t17-,20+/m0/s1	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article	n/a	n/a	8.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA Curated by ChEMBL					Assay Description Inhibition of nucleotide exchange process of oncogenic Ras in vitro				Bioorg Med Chem Lett 6: 195-200 (1996) Article DOI: 10.1016/0960-894X(95)00574-D BindingDB Entry DOI: 10.7270/Q2G160TB
					More data for this Ligand-Target Pair