Compile Data Set for Download or QSAR

Found 114 hits Enz. Inhib. hit(s) with all data for entry = 50047281   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Trypsin (Homo sapiens (Human))	BDBM50158159 (CHEMBL3780036) Show SMILES NC(=N)c1cccc(c1)N1CC(COCc2ccccc2)CN(CC2CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C32H39N5O2/c33-31(34)29-12-7-13-30(18-29)37-22-28(24-39-23-27-10-5-2-6-11-27)21-36(32(37)38)20-26-14-16-35(17-15-26)19-25-8-3-1-4-9-25/h1-13,18,26,28H,14-17,19-24H2,(H3,33,34)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	100	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant trypsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50158155 (CHEMBL3781354) Show SMILES NC(=N)c1cccc(c1)N1CC(CO)CN(CC2CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C25H33N5O2/c26-24(27)22-7-4-8-23(13-22)30-17-21(18-31)16-29(25(30)32)15-20-9-11-28(12-10-20)14-19-5-2-1-3-6-19/h1-8,13,20-21,31H,9-12,14-18H2,(H3,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant trypsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor activator (Homo sapiens (Human))	BDBM50158157 (CHEMBL3780434) Show SMILES COCC1CN(CC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N Show InChI InChI=1S/C26H35N5O2/c1-33-19-22-17-30(26(32)31(18-22)24-9-5-8-23(14-24)25(27)28)16-21-10-12-29(13-11-21)15-20-6-3-2-4-7-20/h2-9,14,21-22H,10-13,15-19H2,1H3,(H3,27,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50158159 (CHEMBL3780036) Show SMILES NC(=N)c1cccc(c1)N1CC(COCc2ccccc2)CN(CC2CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C32H39N5O2/c33-31(34)29-12-7-13-30(18-29)37-22-28(24-39-23-27-10-5-2-6-11-27)21-36(32(37)38)20-26-14-16-35(17-15-26)19-25-8-3-1-4-9-25/h1-13,18,26,28H,14-17,19-24H2,(H3,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	180	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 10a using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50158157 (CHEMBL3780434) Show SMILES COCC1CN(CC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N Show InChI InChI=1S/C26H35N5O2/c1-33-19-22-17-30(26(32)31(18-22)24-9-5-8-23(14-24)25(27)28)16-21-10-12-29(13-11-21)15-20-6-3-2-4-7-20/h2-9,14,21-22H,10-13,15-19H2,1H3,(H3,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 10a using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50158157 (CHEMBL3780434) Show SMILES COCC1CN(CC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N Show InChI InChI=1S/C26H35N5O2/c1-33-19-22-17-30(26(32)31(18-22)24-9-5-8-23(14-24)25(27)28)16-21-10-12-29(13-11-21)15-20-6-3-2-4-7-20/h2-9,14,21-22H,10-13,15-19H2,1H3,(H3,27,28)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant trypsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Serine protease hepsin (Homo sapiens (Human))	BDBM50158154 (CHEMBL3781784) Show SMILES NC(=N)c1cccc(c1)N1CC(O)CN(CC2CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C24H31N5O2/c25-23(26)20-7-4-8-21(13-20)29-17-22(30)16-28(24(29)31)15-19-9-11-27(12-10-19)14-18-5-2-1-3-6-18/h1-8,13,19,22,30H,9-12,14-17H2,(H3,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	210	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor activator (Homo sapiens (Human))	BDBM50158155 (CHEMBL3781354) Show SMILES NC(=N)c1cccc(c1)N1CC(CO)CN(CC2CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C25H33N5O2/c26-24(27)22-7-4-8-23(13-22)30-17-21(18-31)16-29(25(30)32)15-20-9-11-28(12-10-20)14-19-5-2-1-3-6-19/h1-8,13,20-21,31H,9-12,14-18H2,(H3,26,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	230	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50158160 (CHEMBL3780584) Show SMILES CC1CN(C2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N Show InChI InChI=1S/C24H31N5O/c1-18-15-28(21-10-12-27(13-11-21)17-19-6-3-2-4-7-19)24(30)29(16-18)22-9-5-8-20(14-22)23(25)26/h2-9,14,18,21H,10-13,15-17H2,1H3,(H3,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	240	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 10a using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50158155 (CHEMBL3781354) Show SMILES NC(=N)c1cccc(c1)N1CC(CO)CN(CC2CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C25H33N5O2/c26-24(27)22-7-4-8-23(13-22)30-17-21(18-31)16-29(25(30)32)15-20-9-11-28(12-10-20)14-19-5-2-1-3-6-19/h1-8,13,20-21,31H,9-12,14-18H2,(H3,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 10a using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50158154 (CHEMBL3781784) Show SMILES NC(=N)c1cccc(c1)N1CC(O)CN(CC2CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C24H31N5O2/c25-23(26)20-7-4-8-21(13-20)29-17-22(30)16-28(24(29)31)15-19-9-11-27(12-10-19)14-18-5-2-1-3-6-18/h1-8,13,19,22,30H,9-12,14-17H2,(H3,25,26)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant matripase catalytic domain using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Serine protease hepsin (Homo sapiens (Human))	BDBM50158152 (CHEMBL3780269) Show SMILES NC(=N)c1cccc(c1)N1CC(CNC(=O)Cc2ccccc2)CN(CC2CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C33H40N6O2/c34-32(35)29-12-7-13-30(19-29)39-24-28(20-36-31(40)18-25-8-3-1-4-9-25)23-38(33(39)41)22-27-14-16-37(17-15-27)21-26-10-5-2-6-11-26/h1-13,19,27-28H,14-18,20-24H2,(H3,34,35)(H,36,40)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50158101 (CHEMBL3781673) Show SMILES NC(=N)c1cccc(c1)N1CC(CN(CC2CCN(Cc3ccccc3)CC2)C1=O)NS(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C31H38N6O3S/c32-30(33)27-12-7-13-29(18-27)37-22-28(34-41(39,40)23-26-10-5-2-6-11-26)21-36(31(37)38)20-25-14-16-35(17-15-25)19-24-8-3-1-4-9-24/h1-13,18,25,28,34H,14-17,19-23H2,(H3,32,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant trypsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50158151 (CHEMBL3780273) Show SMILES CS(=O)(=O)NC1CN(CC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N Show InChI InChI=1S/C25H34N6O3S/c1-35(33,34)28-22-17-30(25(32)31(18-22)23-9-5-8-21(14-23)24(26)27)16-20-10-12-29(13-11-20)15-19-6-3-2-4-7-19/h2-9,14,20,22,28H,10-13,15-18H2,1H3,(H3,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant matripase catalytic domain using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50158161 (CHEMBL3781405) Show SMILES NC(=N)c1cccc(c1)N1CC(CNC(=O)c2ccccc2)CN(CC2CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C32H38N6O2/c33-30(34)28-12-7-13-29(18-28)38-23-26(19-35-31(39)27-10-5-2-6-11-27)22-37(32(38)40)21-25-14-16-36(17-15-25)20-24-8-3-1-4-9-24/h1-13,18,25-26H,14-17,19-23H2,(H3,33,34)(H,35,39)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant trypsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50158150 (CHEMBL3780005) Show SMILES NC(=N)c1cccc(c1)N1CC(CN(CC2CCN(Cc3ccccc3)CC2)C1=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C30H36N6O3S/c31-29(32)25-10-7-11-27(18-25)36-22-26(33-40(38,39)28-12-5-2-6-13-28)21-35(30(36)37)20-24-14-16-34(17-15-24)19-23-8-3-1-4-9-23/h1-13,18,24,26,33H,14-17,19-22H2,(H3,31,32)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant trypsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor activator (Homo sapiens (Human))	BDBM50158151 (CHEMBL3780273) Show SMILES CS(=O)(=O)NC1CN(CC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N Show InChI InChI=1S/C25H34N6O3S/c1-35(33,34)28-22-17-30(25(32)31(18-22)23-9-5-8-21(14-23)24(26)27)16-20-10-12-29(13-11-20)15-19-6-3-2-4-7-19/h2-9,14,20,22,28H,10-13,15-18H2,1H3,(H3,26,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50158101 (CHEMBL3781673) Show SMILES NC(=N)c1cccc(c1)N1CC(CN(CC2CCN(Cc3ccccc3)CC2)C1=O)NS(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C31H38N6O3S/c32-30(33)27-12-7-13-29(18-27)37-22-28(34-41(39,40)23-26-10-5-2-6-11-26)21-36(31(37)38)20-25-14-16-35(17-15-25)19-24-8-3-1-4-9-24/h1-13,18,25,28,34H,14-17,19-23H2,(H3,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant matripase catalytic domain using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor activator (Homo sapiens (Human))	BDBM50158153 (CHEMBL3780548) Show SMILES NC(=N)c1cccc(c1)N1CC(CN(CC2CCN(Cc3ccccc3)CC2)C1=O)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C32H38N6O2/c33-31(34)27-12-7-13-29(19-27)38-23-28(35-30(39)18-24-8-3-1-4-9-24)22-37(32(38)40)21-26-14-16-36(17-15-26)20-25-10-5-2-6-11-25/h1-13,19,26,28H,14-18,20-23H2,(H3,33,34)(H,35,39)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50157632 (CHEMBL3781349) Show SMILES CC1CN(CC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N Show InChI InChI=1S/C25H33N5O/c1-19-15-29(25(31)30(16-19)23-9-5-8-22(14-23)24(26)27)18-21-10-12-28(13-11-21)17-20-6-3-2-4-7-20/h2-9,14,19,21H,10-13,15-18H2,1H3,(H3,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 10a using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50158154 (CHEMBL3781784) Show SMILES NC(=N)c1cccc(c1)N1CC(O)CN(CC2CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C24H31N5O2/c25-23(26)20-7-4-8-21(13-20)29-17-22(30)16-28(24(29)31)15-19-9-11-27(12-10-19)14-18-5-2-1-3-6-18/h1-8,13,19,22,30H,9-12,14-17H2,(H3,25,26)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	390	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant trypsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50157633 (CHEMBL3779949) Show SMILES CC1CN(CCC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N Show InChI InChI=1S/C26H35N5O/c1-20-17-30(26(32)31(18-20)24-9-5-8-23(16-24)25(27)28)15-12-21-10-13-29(14-11-21)19-22-6-3-2-4-7-22/h2-9,16,20-21H,10-15,17-19H2,1H3,(H3,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	400	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 10a using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50158151 (CHEMBL3780273) Show SMILES CS(=O)(=O)NC1CN(CC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N Show InChI InChI=1S/C25H34N6O3S/c1-35(33,34)28-22-17-30(25(32)31(18-22)23-9-5-8-21(14-23)24(26)27)16-20-10-12-29(13-11-20)15-19-6-3-2-4-7-19/h2-9,14,20,22,28H,10-13,15-18H2,1H3,(H3,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	420	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant trypsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50157632 (CHEMBL3781349) Show SMILES CC1CN(CC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N Show InChI InChI=1S/C25H33N5O/c1-19-15-29(25(31)30(16-19)23-9-5-8-22(14-23)24(26)27)18-21-10-12-28(13-11-21)17-20-6-3-2-4-7-20/h2-9,14,19,21H,10-13,15-18H2,1H3,(H3,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant trypsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor activator (Homo sapiens (Human))	BDBM50158159 (CHEMBL3780036) Show SMILES NC(=N)c1cccc(c1)N1CC(COCc2ccccc2)CN(CC2CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C32H39N5O2/c33-31(34)29-12-7-13-30(18-29)37-22-28(24-39-23-27-10-5-2-6-11-27)21-36(32(37)38)20-26-14-16-35(17-15-26)19-25-8-3-1-4-9-25/h1-13,18,26,28H,14-17,19-24H2,(H3,33,34)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	430	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor activator (Homo sapiens (Human))	BDBM50158101 (CHEMBL3781673) Show SMILES NC(=N)c1cccc(c1)N1CC(CN(CC2CCN(Cc3ccccc3)CC2)C1=O)NS(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C31H38N6O3S/c32-30(33)27-12-7-13-29(18-27)37-22-28(34-41(39,40)23-26-10-5-2-6-11-26)21-36(31(37)38)20-25-14-16-35(17-15-25)19-24-8-3-1-4-9-24/h1-13,18,25,28,34H,14-17,19-23H2,(H3,32,33)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	440	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50158161 (CHEMBL3781405) Show SMILES NC(=N)c1cccc(c1)N1CC(CNC(=O)c2ccccc2)CN(CC2CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C32H38N6O2/c33-30(34)28-12-7-13-29(18-28)38-23-26(19-35-31(39)27-10-5-2-6-11-27)22-37(32(38)40)21-25-14-16-36(17-15-25)20-24-8-3-1-4-9-24/h1-13,18,25-26H,14-17,19-23H2,(H3,33,34)(H,35,39)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	470	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant matripase catalytic domain using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor activator (Homo sapiens (Human))	BDBM50157632 (CHEMBL3781349) Show SMILES CC1CN(CC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N Show InChI InChI=1S/C25H33N5O/c1-19-15-29(25(31)30(16-19)23-9-5-8-22(14-23)24(26)27)18-21-10-12-28(13-11-21)17-20-6-3-2-4-7-20/h2-9,14,19,21H,10-13,15-18H2,1H3,(H3,26,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	480	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50158153 (CHEMBL3780548) Show SMILES NC(=N)c1cccc(c1)N1CC(CN(CC2CCN(Cc3ccccc3)CC2)C1=O)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C32H38N6O2/c33-31(34)27-12-7-13-29(19-27)38-23-28(35-30(39)18-24-8-3-1-4-9-24)22-37(32(38)40)21-26-14-16-36(17-15-26)20-25-10-5-2-6-11-25/h1-13,19,26,28H,14-18,20-23H2,(H3,33,34)(H,35,39)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	500	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Compound was evaluated for potency towards nicotinic acetylcholine receptor in rat P2 brain membranes using [3H]-nicotine as a radioligand				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50157633 (CHEMBL3779949) Show SMILES CC1CN(CCC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N Show InChI InChI=1S/C26H35N5O/c1-20-17-30(26(32)31(18-20)24-9-5-8-23(16-24)25(27)28)15-12-21-10-13-29(14-11-21)19-22-6-3-2-4-7-22/h2-9,16,20-21H,10-15,17-19H2,1H3,(H3,27,28)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant matripase catalytic domain using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50158151 (CHEMBL3780273) Show SMILES CS(=O)(=O)NC1CN(CC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N Show InChI InChI=1S/C25H34N6O3S/c1-35(33,34)28-22-17-30(25(32)31(18-22)23-9-5-8-21(14-23)24(26)27)16-20-10-12-29(13-11-20)15-19-6-3-2-4-7-19/h2-9,14,20,22,28H,10-13,15-18H2,1H3,(H3,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	510	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 10a using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Hepatocyte growth factor activator (Homo sapiens (Human))	BDBM50158150 (CHEMBL3780005) Show SMILES NC(=N)c1cccc(c1)N1CC(CN(CC2CCN(Cc3ccccc3)CC2)C1=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C30H36N6O3S/c31-29(32)25-10-7-11-27(18-25)36-22-26(33-40(38,39)28-12-5-2-6-13-28)21-35(30(36)37)20-24-14-16-34(17-15-24)19-23-8-3-1-4-9-23/h1-13,18,24,26,33H,14-17,19-22H2,(H3,31,32)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant hepatocyte growth factor activator using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50158150 (CHEMBL3780005) Show SMILES NC(=N)c1cccc(c1)N1CC(CN(CC2CCN(Cc3ccccc3)CC2)C1=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C30H36N6O3S/c31-29(32)25-10-7-11-27(18-25)36-22-26(33-40(38,39)28-12-5-2-6-13-28)21-35(30(36)37)20-24-14-16-34(17-15-24)19-23-8-3-1-4-9-23/h1-13,18,24,26,33H,14-17,19-22H2,(H3,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant matripase catalytic domain using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50157632 (CHEMBL3781349) Show SMILES CC1CN(CC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N Show InChI InChI=1S/C25H33N5O/c1-19-15-29(25(31)30(16-19)23-9-5-8-22(14-23)24(26)27)18-21-10-12-28(13-11-21)17-20-6-3-2-4-7-20/h2-9,14,19,21H,10-13,15-18H2,1H3,(H3,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant matripase catalytic domain using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Serine protease hepsin (Homo sapiens (Human))	BDBM50158101 (CHEMBL3781673) Show SMILES NC(=N)c1cccc(c1)N1CC(CN(CC2CCN(Cc3ccccc3)CC2)C1=O)NS(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C31H38N6O3S/c32-30(33)27-12-7-13-29(18-27)37-22-28(34-41(39,40)23-26-10-5-2-6-11-26)21-36(31(37)38)20-25-14-16-35(17-15-25)19-24-8-3-1-4-9-24/h1-13,18,25,28,34H,14-17,19-23H2,(H3,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	530	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Serine protease hepsin (Homo sapiens (Human))	BDBM50157632 (CHEMBL3781349) Show SMILES CC1CN(CC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N Show InChI InChI=1S/C25H33N5O/c1-19-15-29(25(31)30(16-19)23-9-5-8-22(14-23)24(26)27)18-21-10-12-28(13-11-21)17-20-6-3-2-4-7-20/h2-9,14,19,21H,10-13,15-18H2,1H3,(H3,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	540	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50158158 (CHEMBL3780208) Show SMILES NC(=N)c1cccc(c1)N1CC(CN(CC2CCN(Cc3ccccc3)CC2)C1=O)OCc1ccccc1 Show InChI InChI=1S/C31H37N5O2/c32-30(33)27-12-7-13-28(18-27)36-22-29(38-23-26-10-5-2-6-11-26)21-35(31(36)37)20-25-14-16-34(17-15-25)19-24-8-3-1-4-9-24/h1-13,18,25,29H,14-17,19-23H2,(H3,32,33)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	550	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant trypsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Serine protease hepsin (Homo sapiens (Human))	BDBM50158159 (CHEMBL3780036) Show SMILES NC(=N)c1cccc(c1)N1CC(COCc2ccccc2)CN(CC2CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C32H39N5O2/c33-31(34)29-12-7-13-30(18-29)37-22-28(24-39-23-27-10-5-2-6-11-27)21-36(32(37)38)20-26-14-16-35(17-15-26)19-25-8-3-1-4-9-25/h1-13,18,26,28H,14-17,19-24H2,(H3,33,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	560	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Suppressor of tumorigenicity 14 protein (Homo sapiens (Human))	BDBM50158155 (CHEMBL3781354) Show SMILES NC(=N)c1cccc(c1)N1CC(CO)CN(CC2CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C25H33N5O2/c26-24(27)22-7-4-8-23(13-22)30-17-21(18-31)16-29(25(30)32)15-20-9-11-28(12-10-20)14-19-5-2-1-3-6-19/h1-8,13,20-21,31H,9-12,14-18H2,(H3,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	580	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Compound was evaluated for inhibitory activity towards nicotinic acetylcholine receptor in rat P2 brain membranes using [3H]-nicotine as a radioligan...				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50158152 (CHEMBL3780269) Show SMILES NC(=N)c1cccc(c1)N1CC(CNC(=O)Cc2ccccc2)CN(CC2CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C33H40N6O2/c34-32(35)29-12-7-13-30(19-29)39-24-28(20-36-31(40)18-25-8-3-1-4-9-25)23-38(33(39)41)22-27-14-16-37(17-15-27)21-26-10-5-2-6-11-26/h1-13,19,27-28H,14-18,20-24H2,(H3,34,35)(H,36,40)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	590	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant trypsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50158150 (CHEMBL3780005) Show SMILES NC(=N)c1cccc(c1)N1CC(CN(CC2CCN(Cc3ccccc3)CC2)C1=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C30H36N6O3S/c31-29(32)25-10-7-11-27(18-25)36-22-26(33-40(38,39)28-12-5-2-6-13-28)21-35(30(36)37)20-24-14-16-34(17-15-24)19-23-8-3-1-4-9-23/h1-13,18,24,26,33H,14-17,19-22H2,(H3,31,32)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 10a using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50158101 (CHEMBL3781673) Show SMILES NC(=N)c1cccc(c1)N1CC(CN(CC2CCN(Cc3ccccc3)CC2)C1=O)NS(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C31H38N6O3S/c32-30(33)27-12-7-13-29(18-27)37-22-28(34-41(39,40)23-26-10-5-2-6-11-26)21-36(31(37)38)20-25-14-16-35(17-15-25)19-24-8-3-1-4-9-24/h1-13,18,25,28,34H,14-17,19-23H2,(H3,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	660	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 10a using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Serine protease hepsin (Homo sapiens (Human))	BDBM50158150 (CHEMBL3780005) Show SMILES NC(=N)c1cccc(c1)N1CC(CN(CC2CCN(Cc3ccccc3)CC2)C1=O)NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C30H36N6O3S/c31-29(32)25-10-7-11-27(18-25)36-22-26(33-40(38,39)28-12-5-2-6-13-28)21-35(30(36)37)20-24-14-16-34(17-15-24)19-23-8-3-1-4-9-23/h1-13,18,24,26,33H,14-17,19-22H2,(H3,31,32)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	670	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Serine protease hepsin (Homo sapiens (Human))	BDBM50158155 (CHEMBL3781354) Show SMILES NC(=N)c1cccc(c1)N1CC(CO)CN(CC2CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C25H33N5O2/c26-24(27)22-7-4-8-23(13-22)30-17-21(18-31)16-29(25(30)32)15-20-9-11-28(12-10-20)14-19-5-2-1-3-6-19/h1-8,13,20-21,31H,9-12,14-18H2,(H3,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	690	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Serine protease hepsin (Homo sapiens (Human))	BDBM50158151 (CHEMBL3780273) Show SMILES CS(=O)(=O)NC1CN(CC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N Show InChI InChI=1S/C25H34N6O3S/c1-35(33,34)28-22-17-30(25(32)31(18-22)23-9-5-8-21(14-23)24(26)27)16-20-10-12-29(13-11-20)15-19-6-3-2-4-7-19/h2-9,14,20,22,28H,10-13,15-18H2,1H3,(H3,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	720	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50158153 (CHEMBL3780548) Show SMILES NC(=N)c1cccc(c1)N1CC(CN(CC2CCN(Cc3ccccc3)CC2)C1=O)NC(=O)Cc1ccccc1 Show InChI InChI=1S/C32H38N6O2/c33-31(34)27-12-7-13-29(19-27)38-23-28(35-30(39)18-24-8-3-1-4-9-24)22-37(32(38)40)21-26-14-16-36(17-15-26)20-25-10-5-2-6-11-25/h1-13,19,26,28H,14-18,20-23H2,(H3,33,34)(H,35,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	740	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 10a using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Coagulation factor X (Homo sapiens (Human))	BDBM50158161 (CHEMBL3781405) Show SMILES NC(=N)c1cccc(c1)N1CC(CNC(=O)c2ccccc2)CN(CC2CCN(Cc3ccccc3)CC2)C1=O Show InChI InChI=1S/C32H38N6O2/c33-30(34)28-12-7-13-29(18-28)38-23-26(19-35-31(39)27-10-5-2-6-11-27)22-37(32(38)40)21-25-14-16-36(17-15-25)20-24-8-3-1-4-9-24/h1-13,18,25-26H,14-17,19-23H2,(H3,33,34)(H,35,39)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	750	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant factor 10a using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Serine protease hepsin (Homo sapiens (Human))	BDBM50158158 (CHEMBL3780208) Show SMILES NC(=N)c1cccc(c1)N1CC(CN(CC2CCN(Cc3ccccc3)CC2)C1=O)OCc1ccccc1 Show InChI InChI=1S/C31H37N5O2/c32-30(33)27-12-7-13-28(18-27)36-22-29(38-23-26-10-5-2-6-11-26)21-35(31(36)37)20-25-14-16-34(17-15-25)19-24-8-3-1-4-9-24/h1-13,18,25,29H,14-17,19-23H2,(H3,32,33)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Serine protease hepsin (Homo sapiens (Human))	BDBM50158156 (CHEMBL3781626) Show SMILES COC1CN(CC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N Show InChI InChI=1S/C25H33N5O2/c1-32-23-17-29(25(31)30(18-23)22-9-5-8-21(14-22)24(26)27)16-20-10-12-28(13-11-20)15-19-6-3-2-4-7-19/h2-9,14,20,23H,10-13,15-18H2,1H3,(H3,26,27)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant hepsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair
Trypsin (Homo sapiens (Human))	BDBM50158156 (CHEMBL3781626) Show SMILES COC1CN(CC2CCN(Cc3ccccc3)CC2)C(=O)N(C1)c1cccc(c1)C(N)=N Show InChI InChI=1S/C25H33N5O2/c1-32-23-17-29(25(31)30(18-23)22-9-5-8-21(14-22)24(26)27)16-20-10-12-28(13-11-20)15-19-6-3-2-4-7-19/h2-9,14,20,23H,10-13,15-18H2,1H3,(H3,26,27)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	760	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Southern Research Curated by ChEMBL					Assay Description Inhibition of human recombinant trypsin using H2N(EEdansyl)GKQLRVVNGG (KDabcyl)-NH2 as substrate by fluorometric analysis				ACS Med Chem Lett 7: 177-81 (2016) Article DOI: 10.1021/acsmedchemlett.5b00357 BindingDB Entry DOI: 10.7270/Q2Z60QZM
					More data for this Ligand-Target Pair

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