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Compile Data Set for Download or QSAR

Found 85 hits Enz. Inhib. hit(s) with all data for entry = 50047490   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170878
PNG
(CHEMBL3806197)
Show SMILES COc1ccc(CCNCC(N)P(O)(O)=O)cc1
Show InChI InChI=1S/C11H19N2O4P/c1-17-10-4-2-9(3-5-10)6-7-13-8-11(12)18(14,15)16/h2-5,11,13H,6-8,12H2,1H3,(H2,14,15,16)
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65n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170884
PNG
(CHEMBL3805495)
Show SMILES COc1ccc(CCNCC(N)P(O)(=O)CC(Cc2ccccc2)C(O)=O)cc1
Show InChI InChI=1S/C21H29N2O5P/c1-28-19-9-7-16(8-10-19)11-12-23-14-20(22)29(26,27)15-18(21(24)25)13-17-5-3-2-4-6-17/h2-10,18,20,23H,11-15,22H2,1H3,(H,24,25)(H,26,27)
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78n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170883
PNG
(CHEMBL3805118)
Show SMILES NC(CNC1CCCCCC1)P(O)(=O)CC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C19H31N2O4P/c20-18(13-21-17-10-6-1-2-7-11-17)26(24,25)14-16(19(22)23)12-15-8-4-3-5-9-15/h3-5,8-9,16-18,21H,1-2,6-7,10-14,20H2,(H,22,23)(H,24,25)
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207n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Cytosol aminopeptidase [33-68,L62W]


(Sus scrofa (Pig))
BDBM50337147
PNG
((RS)-1-amino-3-cyclohexylpropylphosphonic acid | C...)
Show SMILES NC(CCC1CCCCC1)P(O)(O)=O
Show InChI InChI=1S/C9H20NO3P/c10-9(14(11,12)13)7-6-8-4-2-1-3-5-8/h8-9H,1-7,10H2,(H2,11,12,13)
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210n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney leucine aminopeptidase M17 using Leu-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition meas...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170882
PNG
(CHEMBL3804856)
Show SMILES NC(CNC1CCCCC1)P(O)(=O)CC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C18H29N2O4P/c19-17(12-20-16-9-5-2-6-10-16)25(23,24)13-15(18(21)22)11-14-7-3-1-4-8-14/h1,3-4,7-8,15-17,20H,2,5-6,9-13,19H2,(H,21,22)(H,23,24)
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275n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170900
PNG
(CHEMBL3806247)
Show SMILES CCCCCCNCC(N)P(O)(O)=O
Show InChI InChI=1S/C8H21N2O3P/c1-2-3-4-5-6-10-7-8(9)14(11,12)13/h8,10H,2-7,9H2,1H3,(H2,11,12,13)
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297n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170891
PNG
(CHEMBL3805986)
Show SMILES NC(CNCc1ccccc1)P(O)(O)=O
Show InChI InChI=1S/C9H15N2O3P/c10-9(15(12,13)14)7-11-6-8-4-2-1-3-5-8/h1-5,9,11H,6-7,10H2,(H2,12,13,14)
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341n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170876
PNG
(CHEMBL3805817)
Show SMILES COc1ccc(CNCC(N)P(O)(O)=O)cc1
Show InChI InChI=1S/C10H17N2O4P/c1-16-9-4-2-8(3-5-9)6-12-7-10(11)17(13,14)15/h2-5,10,12H,6-7,11H2,1H3,(H2,13,14,15)
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357n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170892
PNG
(CHEMBL3804861)
Show SMILES CC(NCC(N)P(O)(O)=O)c1ccccc1
Show InChI InChI=1S/C10H17N2O3P/c1-8(9-5-3-2-4-6-9)12-7-10(11)16(13,14)15/h2-6,8,10,12H,7,11H2,1H3,(H2,13,14,15)
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391n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170897
PNG
(CHEMBL3805573)
Show SMILES NC(CNC1CCCCCC1)P(O)(O)=O
Show InChI InChI=1S/C9H21N2O3P/c10-9(15(12,13)14)7-11-8-5-3-1-2-4-6-8/h8-9,11H,1-7,10H2,(H2,12,13,14)
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397n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170881
PNG
(CHEMBL3805028)
Show SMILES CC(C)CNCC(N)P(O)(=O)CC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H27N2O4P/c1-12(2)9-18-10-15(17)23(21,22)11-14(16(19)20)8-13-6-4-3-5-7-13/h3-7,12,14-15,18H,8-11,17H2,1-2H3,(H,19,20)(H,21,22)
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499n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170898
PNG
(CHEMBL3805964)
Show SMILES CN(C)CCNCC(N)P(O)(O)=O
Show InChI InChI=1S/C6H18N3O3P/c1-9(2)4-3-8-5-6(7)13(10,11)12/h6,8H,3-5,7H2,1-2H3,(H2,10,11,12)
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500n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170897
PNG
(CHEMBL3805573)
Show SMILES NC(CNC1CCCCCC1)P(O)(O)=O
Show InChI InChI=1S/C9H21N2O3P/c10-9(15(12,13)14)7-11-8-5-3-1-2-4-6-8/h8-9,11H,1-7,10H2,(H2,12,13,14)
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520n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170890
PNG
(CHEMBL3806072)
Show SMILES NC(CNC1CCCCC1)P(O)(O)=O
Show InChI InChI=1S/C8H19N2O3P/c9-8(14(11,12)13)6-10-7-4-2-1-3-5-7/h7-8,10H,1-6,9H2,(H2,11,12,13)
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691n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170878
PNG
(CHEMBL3806197)
Show SMILES COc1ccc(CCNCC(N)P(O)(O)=O)cc1
Show InChI InChI=1S/C11H19N2O4P/c1-17-10-4-2-9(3-5-10)6-7-13-8-11(12)18(14,15)16/h2-5,11,13H,6-8,12H2,1H3,(H2,14,15,16)
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723n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170895
PNG
(CHEMBL3805487)
Show SMILES NC(CNCC1CCCO1)P(O)(O)=O
Show InChI InChI=1S/C7H17N2O4P/c8-7(14(10,11)12)5-9-4-6-2-1-3-13-6/h6-7,9H,1-5,8H2,(H2,10,11,12)
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782n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170890
PNG
(CHEMBL3806072)
Show SMILES NC(CNC1CCCCC1)P(O)(O)=O
Show InChI InChI=1S/C8H19N2O3P/c9-8(14(11,12)13)6-10-7-4-2-1-3-5-7/h7-8,10H,1-6,9H2,(H2,11,12,13)
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870n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using L-leucine p-nitro-anilide as substrate by spectrophotometric analysis


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170880
PNG
(CHEMBL3806187)
Show SMILES CCCNCC(N)P(O)(=O)CC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C15H25N2O4P/c1-2-8-17-10-14(16)22(20,21)11-13(15(18)19)9-12-6-4-3-5-7-12/h3-7,13-14,17H,2,8-11,16H2,1H3,(H,18,19)(H,20,21)
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1.11E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170900
PNG
(CHEMBL3806247)
Show SMILES CCCCCCNCC(N)P(O)(O)=O
Show InChI InChI=1S/C8H21N2O3P/c1-2-3-4-5-6-10-7-8(9)14(11,12)13/h8,10H,2-7,9H2,1H3,(H2,11,12,13)
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1.21E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170874
PNG
(CHEMBL3805544)
Show SMILES NC(CNCCc1ccccc1)P(O)(O)=O
Show InChI InChI=1S/C10H17N2O3P/c11-10(16(13,14)15)8-12-7-6-9-4-2-1-3-5-9/h1-5,10,12H,6-8,11H2,(H2,13,14,15)
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1.22E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170884
PNG
(CHEMBL3805495)
Show SMILES COc1ccc(CCNCC(N)P(O)(=O)CC(Cc2ccccc2)C(O)=O)cc1
Show InChI InChI=1S/C21H29N2O5P/c1-28-19-9-7-16(8-10-19)11-12-23-14-20(22)29(26,27)15-18(21(24)25)13-17-5-3-2-4-6-17/h2-10,18,20,23H,11-15,22H2,1H3,(H,24,25)(H,26,27)
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1.48E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170875
PNG
(CHEMBL3805288)
Show SMILES NC(CNCc1ccc(N)cc1)P(O)(O)=O
Show InChI InChI=1S/C9H16N3O3P/c10-8-3-1-7(2-4-8)5-12-6-9(11)16(13,14)15/h1-4,9,12H,5-6,10-11H2,(H2,13,14,15)
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1.49E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170888
PNG
(CHEMBL3805557)
Show SMILES CCCNCC(N)P(O)(O)=O
Show InChI InChI=1S/C5H15N2O3P/c1-2-3-7-4-5(6)11(8,9)10/h5,7H,2-4,6H2,1H3,(H2,8,9,10)
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1.66E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170889
PNG
(CHEMBL3805798)
Show SMILES CC(C)CNCC(N)P(O)(O)=O
Show InChI InChI=1S/C6H17N2O3P/c1-5(2)3-8-4-6(7)12(9,10)11/h5-6,8H,3-4,7H2,1-2H3,(H2,9,10,11)
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1.71E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using L-leucine p-nitro-anilide as substrate by spectrophotometric analysis


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170888
PNG
(CHEMBL3805557)
Show SMILES CCCNCC(N)P(O)(O)=O
Show InChI InChI=1S/C5H15N2O3P/c1-2-3-7-4-5(6)11(8,9)10/h5,7H,2-4,6H2,1H3,(H2,8,9,10)
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1.91E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using L-leucine p-nitro-anilide as substrate by spectrophotometric analysis


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170876
PNG
(CHEMBL3805817)
Show SMILES COc1ccc(CNCC(N)P(O)(O)=O)cc1
Show InChI InChI=1S/C10H17N2O4P/c1-16-9-4-2-8(3-5-9)6-12-7-10(11)17(13,14)15/h2-5,10,12H,6-7,11H2,1H3,(H2,13,14,15)
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2.29E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170891
PNG
(CHEMBL3805986)
Show SMILES NC(CNCc1ccccc1)P(O)(O)=O
Show InChI InChI=1S/C9H15N2O3P/c10-9(15(12,13)14)7-11-6-8-4-2-1-3-5-8/h1-5,9,11H,6-7,10H2,(H2,12,13,14)
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2.30E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using L-leucine p-nitro-anilide as substrate by spectrophotometric analysis


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170875
PNG
(CHEMBL3805288)
Show SMILES NC(CNCc1ccc(N)cc1)P(O)(O)=O
Show InChI InChI=1S/C9H16N3O3P/c10-8-3-1-7(2-4-8)5-12-6-9(11)16(13,14)15/h1-4,9,12H,5-6,10-11H2,(H2,13,14,15)
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2.49E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170889
PNG
(CHEMBL3805798)
Show SMILES CC(C)CNCC(N)P(O)(O)=O
Show InChI InChI=1S/C6H17N2O3P/c1-5(2)3-8-4-6(7)12(9,10)11/h5-6,8H,3-4,7H2,1-2H3,(H2,9,10,11)
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2.51E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170873
PNG
(CHEMBL3805193)
Show SMILES CC(C)(C)c1ccc(CNCC(N)P(O)(O)=O)cc1
Show InChI InChI=1S/C13H23N2O3P/c1-13(2,3)11-6-4-10(5-7-11)8-15-9-12(14)19(16,17)18/h4-7,12,15H,8-9,14H2,1-3H3,(H2,16,17,18)
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2.55E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170892
PNG
(CHEMBL3804861)
Show SMILES CC(NCC(N)P(O)(O)=O)c1ccccc1
Show InChI InChI=1S/C10H17N2O3P/c1-8(9-5-3-2-4-6-9)12-7-10(11)16(13,14)15/h2-6,8,10,12H,7,11H2,1H3,(H2,13,14,15)
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2.80E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using L-leucine p-nitro-anilide as substrate by spectrophotometric analysis


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170885
PNG
(CHEMBL3806121)
Show SMILES NCC(N)P(O)(O)=O
Show InChI InChI=1S/C2H9N2O3P/c3-1-2(4)8(5,6)7/h2H,1,3-4H2,(H2,5,6,7)
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2.88E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170877
PNG
(CHEMBL3804956)
Show SMILES NCc1ccc(CNCC(N)P(O)(O)=O)cc1
Show InChI InChI=1S/C10H18N3O3P/c11-5-8-1-3-9(4-2-8)6-13-7-10(12)17(14,15)16/h1-4,10,13H,5-7,11-12H2,(H2,14,15,16)
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2.89E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170871
PNG
(CHEMBL3806230)
Show SMILES NC(CNCCN1CCNCC1)P(O)(O)=O
Show InChI InChI=1S/C8H21N4O3P/c9-8(16(13,14)15)7-11-3-6-12-4-1-10-2-5-12/h8,10-11H,1-7,9H2,(H2,13,14,15)
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3.22E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170883
PNG
(CHEMBL3805118)
Show SMILES NC(CNC1CCCCCC1)P(O)(=O)CC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C19H31N2O4P/c20-18(13-21-17-10-6-1-2-7-11-17)26(24,25)14-16(19(22)23)12-15-8-4-3-5-9-15/h3-5,8-9,16-18,21H,1-2,6-7,10-14,20H2,(H,22,23)(H,24,25)
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3.24E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170894
PNG
(CHEMBL3805338)
Show SMILES NC(CNCC1CCNCC1)P(O)(O)=O
Show InChI InChI=1S/C8H20N3O3P/c9-8(15(12,13)14)6-11-5-7-1-3-10-4-2-7/h7-8,10-11H,1-6,9H2,(H2,12,13,14)
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3.29E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170895
PNG
(CHEMBL3805487)
Show SMILES NC(CNCC1CCCO1)P(O)(O)=O
Show InChI InChI=1S/C7H17N2O4P/c8-7(14(10,11)12)5-9-4-6-2-1-3-13-6/h6-7,9H,1-5,8H2,(H2,10,11,12)
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3.64E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170882
PNG
(CHEMBL3804856)
Show SMILES NC(CNC1CCCCC1)P(O)(=O)CC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C18H29N2O4P/c19-17(12-20-16-9-5-2-6-10-16)25(23,24)13-15(18(21)22)11-14-7-3-1-4-8-14/h1,3-4,7-8,15-17,20H,2,5-6,9-13,19H2,(H,21,22)(H,23,24)
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3.83E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170879
PNG
(CHEMBL3805472)
Show SMILES NCC(N)P(O)(=O)CC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C12H19N2O4P/c13-7-11(14)19(17,18)8-10(12(15)16)6-9-4-2-1-3-5-9/h1-5,10-11H,6-8,13-14H2,(H,15,16)(H,17,18)
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4.45E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170881
PNG
(CHEMBL3805028)
Show SMILES CC(C)CNCC(N)P(O)(=O)CC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C16H27N2O4P/c1-12(2)9-18-10-15(17)23(21,22)11-14(16(19)20)8-13-6-4-3-5-7-13/h3-7,12,14-15,18H,8-11,17H2,1-2H3,(H,19,20)(H,21,22)
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4.54E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170877
PNG
(CHEMBL3804956)
Show SMILES NCc1ccc(CNCC(N)P(O)(O)=O)cc1
Show InChI InChI=1S/C10H18N3O3P/c11-5-8-1-3-9(4-2-8)6-13-7-10(12)17(14,15)16/h1-4,10,13H,5-7,11-12H2,(H2,14,15,16)
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5.42E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170898
PNG
(CHEMBL3805964)
Show SMILES CN(C)CCNCC(N)P(O)(O)=O
Show InChI InChI=1S/C6H18N3O3P/c1-9(2)4-3-8-5-6(7)13(10,11)12/h6,8H,3-5,7H2,1-2H3,(H2,10,11,12)
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5.74E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170874
PNG
(CHEMBL3805544)
Show SMILES NC(CNCCc1ccccc1)P(O)(O)=O
Show InChI InChI=1S/C10H17N2O3P/c11-10(16(13,14)15)8-12-7-6-9-4-2-1-3-5-9/h1-5,10,12H,6-8,11H2,(H2,13,14,15)
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6.04E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170893
PNG
(CHEMBL3804843)
Show SMILES NC(CN1CCCCC1)P(O)(O)=O
Show InChI InChI=1S/C7H17N2O3P/c8-7(13(10,11)12)6-9-4-2-1-3-5-9/h7H,1-6,8H2,(H2,10,11,12)
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6.04E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170873
PNG
(CHEMBL3805193)
Show SMILES CC(C)(C)c1ccc(CNCC(N)P(O)(O)=O)cc1
Show InChI InChI=1S/C13H23N2O3P/c1-13(2,3)11-6-4-10(5-7-11)8-15-9-12(14)19(16,17)18/h4-7,12,15H,8-9,14H2,1-3H3,(H2,16,17,18)
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6.58E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170880
PNG
(CHEMBL3806187)
Show SMILES CCCNCC(N)P(O)(=O)CC(Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C15H25N2O4P/c1-2-8-17-10-14(16)22(20,21)11-13(15(18)19)9-12-6-4-3-5-7-12/h3-7,13-14,17H,2,8-11,16H2,1H3,(H,18,19)(H,20,21)
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6.74E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170871
PNG
(CHEMBL3806230)
Show SMILES NC(CNCCN1CCNCC1)P(O)(O)=O
Show InChI InChI=1S/C8H21N4O3P/c9-8(16(13,14)15)7-11-3-6-12-4-1-10-2-5-12/h8,10-11H,1-7,9H2,(H2,13,14,15)
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7.00E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Cytosol aminopeptidase [33-68,L62W]


(Sus scrofa (Pig))
BDBM50170875
PNG
(CHEMBL3805288)
Show SMILES NC(CNCc1ccc(N)cc1)P(O)(O)=O
Show InChI InChI=1S/C9H16N3O3P/c10-8-3-1-7(2-4-8)5-12-6-9(11)16(13,14)15/h1-4,9,12H,5-6,10-11H2,(H2,13,14,15)
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7.02E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of porcine kidney leucine aminopeptidase M17 using Leu-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition meas...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Homo sapiens (Human))
BDBM50170886
PNG
(CHEMBL3804959)
Show SMILES CNCC(N)P(O)(O)=O
Show InChI InChI=1S/C3H11N2O3P/c1-5-2-3(4)9(6,7)8/h3,5H,2,4H2,1H3,(H2,6,7,8)
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7.42E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of recombinant human alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition mea...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
Aminopeptidase N


(Sus scrofa (Pig))
BDBM50170894
PNG
(CHEMBL3805338)
Show SMILES NC(CNCC1CCNCC1)P(O)(O)=O
Show InChI InChI=1S/C8H20N3O3P/c9-8(15(12,13)14)6-11-5-7-1-3-10-4-2-7/h7-8,10-11H,1-6,9H2,(H2,12,13,14)
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9.39E+3n/an/an/an/an/an/an/an/a



Wroclaw University of Technology

Curated by ChEMBL


Assay Description
Inhibition of pig kidney alanyl aminopeptidase M1 using Ala-AMC as substrate preincubated for 30 to 60 mins followed by substrate addition measured f...


Eur J Med Chem 117: 187-96 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.018
BindingDB Entry DOI: 10.7270/Q2BC41F8
More data for this
Ligand-Target Pair
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