Found 45 hits Enz. Inhib. hit(s) with all data for entry = 50047614 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50178978
(CHEMBL3815112)Show SMILES COc1ccc(CCN(CCCc2ccccc2F)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32FNO4/c1-31-25-11-9-21(18-27(25)32-2)13-16-30(15-5-7-23-6-3-4-8-24(23)29)17-14-22-10-12-26-28(19-22)34-20-33-26/h3-4,6,8-12,18-19H,5,7,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]LSD from human 5-HT2B receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50001775
((ritanserin)6-(2-{4-[Bis-(4-fluoro-phenyl)-methyle...)Show SMILES [#6]-c1nc2sccn2c(=O)c1-[#6]-[#6]-[#7]-1-[#6]-[#6]\[#6](-[#6]-[#6]-1)=[#6](\c1ccc(F)cc1)-c1ccc(F)cc1 Show InChI InChI=1S/C27H25F2N3OS/c1-18-24(26(33)32-16-17-34-27(32)30-18)12-15-31-13-10-21(11-14-31)25(19-2-6-22(28)7-3-19)20-4-8-23(29)9-5-20/h2-9,16-17H,10-15H2,1H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| 1.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]mesulergine from human 5-HT2C receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50178979
(CHEMBL3813796)Show SMILES COc1ccc(CCN(CCCc2ccccc2Cl)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32ClNO4/c1-31-25-11-9-21(18-27(25)32-2)13-16-30(15-5-7-23-6-3-4-8-24(23)29)17-14-22-10-12-26-28(19-22)34-20-33-26/h3-4,6,8-12,18-19H,5,7,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]LSD from human 5-HT2B receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50178980
(CHEMBL3813726)Show SMILES COc1ccc(CCN(CCCc2ccccc2Br)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32BrNO4/c1-31-25-11-9-21(18-27(25)32-2)13-16-30(15-5-7-23-6-3-4-8-24(23)29)17-14-22-10-12-26-28(19-22)34-20-33-26/h3-4,6,8-12,18-19H,5,7,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]LSD from human 5-HT2B receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50178981
(CHEMBL3813855)Show SMILES COc1ccc(CCN(CCCc2ccccc2I)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32INO4/c1-31-25-11-9-21(18-27(25)32-2)13-16-30(15-5-7-23-6-3-4-8-24(23)29)17-14-22-10-12-26-28(19-22)34-20-33-26/h3-4,6,8-12,18-19H,5,7,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 13 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]LSD from human 5-HT2B receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50178964
(CHEMBL3814737)Show SMILES COc1ccc(CCN(CCCc2ccc(F)cc2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32FNO4/c1-31-25-11-7-22(18-27(25)32-2)13-16-30(15-3-4-21-5-9-24(29)10-6-21)17-14-23-8-12-26-28(19-23)34-20-33-26/h5-12,18-19H,3-4,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]LSD from human 5-HT2B receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50178973
(CHEMBL3815066)Show SMILES COc1ccc(CCN(CCCc2cccc(Br)c2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32BrNO4/c1-31-25-10-8-22(18-27(25)32-2)12-15-30(14-4-6-21-5-3-7-24(29)17-21)16-13-23-9-11-26-28(19-23)34-20-33-26/h3,5,7-11,17-19H,4,6,12-16,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 14 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]LSD from human 5-HT2B receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50001884
(2-[4-(4-Methyl-benzyl)-piperazin-1-yl]-1-(2-methyl...)Show SMILES CN1CCN(CC1)C1=Nc2cc(Cl)ccc2Nc2ccccc12 |t:8| Show InChI InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL DrugBank MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 15 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50178969
(CHEMBL3814821)Show SMILES COc1ccc(CCN(CCCc2cccc(Cl)c2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32ClNO4/c1-31-25-10-8-22(18-27(25)32-2)12-15-30(14-4-6-21-5-3-7-24(29)17-21)16-13-23-9-11-26-28(19-23)34-20-33-26/h3,5,7-11,17-19H,4,6,12-16,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 17 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]LSD from human 5-HT2B receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50178968
(CHEMBL3815000)Show SMILES COc1ccc(CCN(CCCc2cccc(F)c2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32FNO4/c1-31-25-10-8-22(18-27(25)32-2)12-15-30(14-4-6-21-5-3-7-24(29)17-21)16-13-23-9-11-26-28(19-23)34-20-33-26/h3,5,7-11,17-19H,4,6,12-16,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]LSD from human 5-HT2B receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50178977
(CHEMBL3814559)Show SMILES COc1ccc(CCN(CCCc2cccc(I)c2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32INO4/c1-31-25-10-8-22(18-27(25)32-2)12-15-30(14-4-6-21-5-3-7-24(29)17-21)16-13-23-9-11-26-28(19-23)34-20-33-26/h3,5,7-11,17-19H,4,6,12-16,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 18 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]LSD from human 5-HT2B receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM82272
(SB 200646 | SB200646a)Show InChI InChI=1S/C15H14N4O/c1-19-8-6-11-9-12(4-5-14(11)19)17-15(20)18-13-3-2-7-16-10-13/h2-10H,1H3,(H2,17,18,20) | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 21 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]LSD from human 5-HT2B receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50178963
(CHEMBL3735756)Show SMILES COc1ccc(CCN(CCCc2ccccc2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H33NO4/c1-30-25-12-10-23(19-27(25)31-2)14-17-29(16-6-9-22-7-4-3-5-8-22)18-15-24-11-13-26-28(20-24)33-21-32-26/h3-5,7-8,10-13,19-20H,6,9,14-18,21H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 26 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]LSD from human 5-HT2B receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50178979
(CHEMBL3813796)Show SMILES COc1ccc(CCN(CCCc2ccccc2Cl)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32ClNO4/c1-31-25-11-9-21(18-27(25)32-2)13-16-30(15-5-7-23-6-3-4-8-24(23)29)17-14-22-10-12-26-28(19-22)34-20-33-26/h3-4,6,8-12,18-19H,5,7,13-17,20H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50178966
(CHEMBL3814485)Show SMILES COc1ccc(CCN(CCCc2ccc(Br)cc2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32BrNO4/c1-31-25-11-7-22(18-27(25)32-2)13-16-30(15-3-4-21-5-9-24(29)10-6-21)17-14-23-8-12-26-28(19-23)34-20-33-26/h5-12,18-19H,3-4,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 45 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]LSD from human 5-HT2B receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50178967
(CHEMBL3813789)Show SMILES COc1ccc(CCN(CCCc2ccc(I)cc2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32INO4/c1-31-25-11-7-22(18-27(25)32-2)13-16-30(15-3-4-21-5-9-24(29)10-6-21)17-14-23-8-12-26-28(19-23)34-20-33-26/h5-12,18-19H,3-4,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 51 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]LSD from human 5-HT2B receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50178980
(CHEMBL3813726)Show SMILES COc1ccc(CCN(CCCc2ccccc2Br)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32BrNO4/c1-31-25-11-9-21(18-27(25)32-2)13-16-30(15-5-7-23-6-3-4-8-24(23)29)17-14-22-10-12-26-28(19-22)34-20-33-26/h3-4,6,8-12,18-19H,5,7,13-17,20H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50178965
(CHEMBL3814708)Show SMILES COc1ccc(CCN(CCCc2ccc(Cl)cc2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32ClNO4/c1-31-25-11-7-22(18-27(25)32-2)13-16-30(15-3-4-21-5-9-24(29)10-6-21)17-14-23-8-12-26-28(19-23)34-20-33-26/h5-12,18-19H,3-4,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 54 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]LSD from human 5-HT2B receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50178978
(CHEMBL3815112)Show SMILES COc1ccc(CCN(CCCc2ccccc2F)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32FNO4/c1-31-25-11-9-21(18-27(25)32-2)13-16-30(15-5-7-23-6-3-4-8-24(23)29)17-14-22-10-12-26-28(19-22)34-20-33-26/h3-4,6,8-12,18-19H,5,7,13-17,20H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 65 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50178981
(CHEMBL3813855)Show SMILES COc1ccc(CCN(CCCc2ccccc2I)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32INO4/c1-31-25-11-9-21(18-27(25)32-2)13-16-30(15-5-7-23-6-3-4-8-24(23)29)17-14-22-10-12-26-28(19-22)34-20-33-26/h3-4,6,8-12,18-19H,5,7,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 68 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]mesulergine from human 5-HT2C receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50178981
(CHEMBL3813855)Show SMILES COc1ccc(CCN(CCCc2ccccc2I)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32INO4/c1-31-25-11-9-21(18-27(25)32-2)13-16-30(15-5-7-23-6-3-4-8-24(23)29)17-14-22-10-12-26-28(19-22)34-20-33-26/h3-4,6,8-12,18-19H,5,7,13-17,20H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 75 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50178978
(CHEMBL3815112)Show SMILES COc1ccc(CCN(CCCc2ccccc2F)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32FNO4/c1-31-25-11-9-21(18-27(25)32-2)13-16-30(15-5-7-23-6-3-4-8-24(23)29)17-14-22-10-12-26-28(19-22)34-20-33-26/h3-4,6,8-12,18-19H,5,7,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 79 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]mesulergine from human 5-HT2C receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50178979
(CHEMBL3813796)Show SMILES COc1ccc(CCN(CCCc2ccccc2Cl)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32ClNO4/c1-31-25-11-9-21(18-27(25)32-2)13-16-30(15-5-7-23-6-3-4-8-24(23)29)17-14-22-10-12-26-28(19-22)34-20-33-26/h3-4,6,8-12,18-19H,5,7,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 92 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]mesulergine from human 5-HT2C receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50178973
(CHEMBL3815066)Show SMILES COc1ccc(CCN(CCCc2cccc(Br)c2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32BrNO4/c1-31-25-10-8-22(18-27(25)32-2)12-15-30(14-4-6-21-5-3-7-24(29)17-21)16-13-23-9-11-26-28(19-23)34-20-33-26/h3,5,7-11,17-19H,4,6,12-16,20H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 103 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50178980
(CHEMBL3813726)Show SMILES COc1ccc(CCN(CCCc2ccccc2Br)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32BrNO4/c1-31-25-11-9-21(18-27(25)32-2)13-16-30(15-5-7-23-6-3-4-8-24(23)29)17-14-22-10-12-26-28(19-22)34-20-33-26/h3-4,6,8-12,18-19H,5,7,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 124 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]mesulergine from human 5-HT2C receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50178969
(CHEMBL3814821)Show SMILES COc1ccc(CCN(CCCc2cccc(Cl)c2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32ClNO4/c1-31-25-10-8-22(18-27(25)32-2)12-15-30(14-4-6-21-5-3-7-24(29)17-21)16-13-23-9-11-26-28(19-23)34-20-33-26/h3,5,7-11,17-19H,4,6,12-16,20H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 125 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50178964
(CHEMBL3814737)Show SMILES COc1ccc(CCN(CCCc2ccc(F)cc2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32FNO4/c1-31-25-11-7-22(18-27(25)32-2)13-16-30(15-3-4-21-5-9-24(29)10-6-21)17-14-23-8-12-26-28(19-23)34-20-33-26/h5-12,18-19H,3-4,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 126 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]mesulergine from human 5-HT2C receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50178973
(CHEMBL3815066)Show SMILES COc1ccc(CCN(CCCc2cccc(Br)c2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32BrNO4/c1-31-25-10-8-22(18-27(25)32-2)12-15-30(14-4-6-21-5-3-7-24(29)17-21)16-13-23-9-11-26-28(19-23)34-20-33-26/h3,5,7-11,17-19H,4,6,12-16,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 143 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]mesulergine from human 5-HT2C receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50178977
(CHEMBL3814559)Show SMILES COc1ccc(CCN(CCCc2cccc(I)c2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32INO4/c1-31-25-10-8-22(18-27(25)32-2)12-15-30(14-4-6-21-5-3-7-24(29)17-21)16-13-23-9-11-26-28(19-23)34-20-33-26/h3,5,7-11,17-19H,4,6,12-16,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 154 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]mesulergine from human 5-HT2C receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50178963
(CHEMBL3735756)Show SMILES COc1ccc(CCN(CCCc2ccccc2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H33NO4/c1-30-25-12-10-23(19-27(25)31-2)14-17-29(16-6-9-22-7-4-3-5-8-22)18-15-24-11-13-26-28(20-24)33-21-32-26/h3-5,7-8,10-13,19-20H,6,9,14-18,21H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 165 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50178968
(CHEMBL3815000)Show SMILES COc1ccc(CCN(CCCc2cccc(F)c2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32FNO4/c1-31-25-10-8-22(18-27(25)32-2)12-15-30(14-4-6-21-5-3-7-24(29)17-21)16-13-23-9-11-26-28(19-23)34-20-33-26/h3,5,7-11,17-19H,4,6,12-16,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 167 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]mesulergine from human 5-HT2C receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50178977
(CHEMBL3814559)Show SMILES COc1ccc(CCN(CCCc2cccc(I)c2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32INO4/c1-31-25-10-8-22(18-27(25)32-2)12-15-30(14-4-6-21-5-3-7-24(29)17-21)16-13-23-9-11-26-28(19-23)34-20-33-26/h3,5,7-11,17-19H,4,6,12-16,20H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 169 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50178968
(CHEMBL3815000)Show SMILES COc1ccc(CCN(CCCc2cccc(F)c2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32FNO4/c1-31-25-10-8-22(18-27(25)32-2)12-15-30(14-4-6-21-5-3-7-24(29)17-21)16-13-23-9-11-26-28(19-23)34-20-33-26/h3,5,7-11,17-19H,4,6,12-16,20H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 185 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50178964
(CHEMBL3814737)Show SMILES COc1ccc(CCN(CCCc2ccc(F)cc2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32FNO4/c1-31-25-11-7-22(18-27(25)32-2)13-16-30(15-3-4-21-5-9-24(29)10-6-21)17-14-23-8-12-26-28(19-23)34-20-33-26/h5-12,18-19H,3-4,13-17,20H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 185 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50178969
(CHEMBL3814821)Show SMILES COc1ccc(CCN(CCCc2cccc(Cl)c2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32ClNO4/c1-31-25-10-8-22(18-27(25)32-2)12-15-30(14-4-6-21-5-3-7-24(29)17-21)16-13-23-9-11-26-28(19-23)34-20-33-26/h3,5,7-11,17-19H,4,6,12-16,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 206 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]mesulergine from human 5-HT2C receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50178966
(CHEMBL3814485)Show SMILES COc1ccc(CCN(CCCc2ccc(Br)cc2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32BrNO4/c1-31-25-11-7-22(18-27(25)32-2)13-16-30(15-3-4-21-5-9-24(29)10-6-21)17-14-23-8-12-26-28(19-23)34-20-33-26/h5-12,18-19H,3-4,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 219 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]mesulergine from human 5-HT2C receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50178966
(CHEMBL3814485)Show SMILES COc1ccc(CCN(CCCc2ccc(Br)cc2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32BrNO4/c1-31-25-11-7-22(18-27(25)32-2)13-16-30(15-3-4-21-5-9-24(29)10-6-21)17-14-23-8-12-26-28(19-23)34-20-33-26/h5-12,18-19H,3-4,13-17,20H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 221 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50178967
(CHEMBL3813789)Show SMILES COc1ccc(CCN(CCCc2ccc(I)cc2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32INO4/c1-31-25-11-7-22(18-27(25)32-2)13-16-30(15-3-4-21-5-9-24(29)10-6-21)17-14-23-8-12-26-28(19-23)34-20-33-26/h5-12,18-19H,3-4,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 224 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]mesulergine from human 5-HT2C receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50178965
(CHEMBL3814708)Show SMILES COc1ccc(CCN(CCCc2ccc(Cl)cc2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32ClNO4/c1-31-25-11-7-22(18-27(25)32-2)13-16-30(15-3-4-21-5-9-24(29)10-6-21)17-14-23-8-12-26-28(19-23)34-20-33-26/h5-12,18-19H,3-4,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 235 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]mesulergine from human 5-HT2C receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50178967
(CHEMBL3813789)Show SMILES COc1ccc(CCN(CCCc2ccc(I)cc2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32INO4/c1-31-25-11-7-22(18-27(25)32-2)13-16-30(15-3-4-21-5-9-24(29)10-6-21)17-14-23-8-12-26-28(19-23)34-20-33-26/h5-12,18-19H,3-4,13-17,20H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 288 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2A
(Homo sapiens (Human)) | BDBM50178965
(CHEMBL3814708)Show SMILES COc1ccc(CCN(CCCc2ccc(Cl)cc2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32ClNO4/c1-31-25-11-7-22(18-27(25)32-2)13-16-30(15-3-4-21-5-9-24(29)10-6-21)17-14-23-8-12-26-28(19-23)34-20-33-26/h5-12,18-19H,3-4,13-17,20H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 365 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]ketanserin from human 5-HT2A receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2C
(Homo sapiens (Human)) | BDBM50178963
(CHEMBL3735756)Show SMILES COc1ccc(CCN(CCCc2ccccc2)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H33NO4/c1-30-25-12-10-23(19-27(25)31-2)14-17-29(16-6-9-22-7-4-3-5-8-22)18-15-24-11-13-26-28(20-24)33-21-32-26/h3-5,7-8,10-13,19-20H,6,9,14-18,21H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 399 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Displacement of [3H]mesulergine from human 5-HT2C receptor measured after 90 mins by microbeta scintillation counting method |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50178979
(CHEMBL3813796)Show SMILES COc1ccc(CCN(CCCc2ccccc2Cl)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32ClNO4/c1-31-25-11-9-21(18-27(25)32-2)13-16-30(15-5-7-23-6-3-4-8-24(23)29)17-14-22-10-12-26-28(19-22)34-20-33-26/h3-4,6,8-12,18-19H,5,7,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 99 | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Antagonist activity at human 5-HT2B receptor by PDSP assay |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50178978
(CHEMBL3815112)Show SMILES COc1ccc(CCN(CCCc2ccccc2F)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32FNO4/c1-31-25-11-9-21(18-27(25)32-2)13-16-30(15-5-7-23-6-3-4-8-24(23)29)17-14-22-10-12-26-28(19-22)34-20-33-26/h3-4,6,8-12,18-19H,5,7,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 135 | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Antagonist activity at human 5-HT2B receptor by PDSP assay |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |
5-hydroxytryptamine receptor 2B
(Homo sapiens (Human)) | BDBM50178980
(CHEMBL3813726)Show SMILES COc1ccc(CCN(CCCc2ccccc2Br)CCc2ccc3OCOc3c2)cc1OC Show InChI InChI=1S/C28H32BrNO4/c1-31-25-11-9-21(18-27(25)32-2)13-16-30(15-5-7-23-6-3-4-8-24(23)29)17-14-22-10-12-26-28(19-22)34-20-33-26/h3-4,6,8-12,18-19H,5,7,13-17,20H2,1-2H3 | PDB
Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 326 | n/a | n/a | n/a | n/a | n/a | n/a |
City University Of New York
Curated by ChEMBL
| Assay Description Antagonist activity at human 5-HT2B receptor by PDSP assay |
Bioorg Med Chem Lett 26: 3216-3219 (2016)
Article DOI: 10.1016/j.bmcl.2016.05.079 BindingDB Entry DOI: 10.7270/Q29S1SXB |
More data for this Ligand-Target Pair | |