BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with all data for entry = 50047724
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50185750 (CHEMBL3824229) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.03E+4	n/a	n/a	n/a	n/a	n/a	n/a
College of Chemical and Environmental Engineering Curated by ChEMBL					Assay Description Inhibition of PRC2 EZH2 sub unit (unknown origin) assessed as inhibition of SAM-mediated methyl transfer process preincubated for 15 mins followed by...				Bioorg Med Chem Lett 26: 3813-7 (2016) Article DOI: 10.1016/j.bmcl.2016.05.018 BindingDB Entry DOI: 10.7270/Q23N259Z
					More data for this Ligand-Target Pair
Histone-lysine N-methyltransferase EZH2 (Homo sapiens (Human))	BDBM50185751 (CHEMBL1602143) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.26E+4	n/a	n/a	n/a	n/a	n/a	n/a
College of Chemical and Environmental Engineering Curated by ChEMBL					Assay Description Inhibition of PRC2 EZH2 sub unit (unknown origin) assessed as inhibition of SAM-mediated methyl transfer process preincubated for 15 mins followed by...				Bioorg Med Chem Lett 26: 3813-7 (2016) Article DOI: 10.1016/j.bmcl.2016.05.018 BindingDB Entry DOI: 10.7270/Q23N259Z
					More data for this Ligand-Target Pair