Compile Data Set for Download or QSAR

Found 41 hits Enz. Inhib. hit(s) with all data for entry = 50030308   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50294115 (CHEMBL550222 | N-(4-(4-(2-(methylthio)phenyl)piper...) Show SMILES CSc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccn3n2)CC1 Show InChI InChI=1S/C23H29N5OS/c1-30-22-10-3-2-9-21(22)27-16-14-26(15-17-27)12-7-5-11-24-23(29)20-18-19-8-4-6-13-28(19)25-20/h2-4,6,8-10,13,18H,5,7,11-12,14-17H2,1H3,(H,24,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50294115 (CHEMBL550222 | N-(4-(4-(2-(methylthio)phenyl)piper...) Show SMILES CSc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccn3n2)CC1 Show InChI InChI=1S/C23H29N5OS/c1-30-22-10-3-2-9-21(22)27-16-14-26(15-17-27)12-7-5-11-24-23(29)20-18-19-8-4-6-13-28(19)25-20/h2-4,6,8-10,13,18H,5,7,11-12,14-17H2,1H3,(H,24,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.630	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D4 receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50294117 (2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)H-pyr...) Show SMILES COc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C19H22N4O/c1-24-19-8-3-2-7-18(19)22-12-10-21(11-13-22)15-16-14-17-6-4-5-9-23(17)20-16/h2-9,14H,10-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50294116 (CHEMBL561763 | N-[3-[4-(2-Methylsulfanylphenyl)pip...) Show SMILES CSc1ccccc1N1CCN(CCCNC(=O)c2cnn3ccccc23)CC1 Show InChI InChI=1S/C22H27N5OS/c1-29-21-9-3-2-8-20(21)26-15-13-25(14-16-26)11-6-10-23-22(28)18-17-24-27-12-5-4-7-19(18)27/h2-5,7-9,12,17H,6,10-11,13-16H2,1H3,(H,23,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	1.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50119391 (CHEMBL142020 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccn3n2)CC1 Show InChI InChI=1S/C23H29N5O2/c1-30-22-10-3-2-9-21(22)27-16-14-26(15-17-27)12-7-5-11-24-23(29)20-18-19-8-4-6-13-28(19)25-20/h2-4,6,8-10,13,18H,5,7,11-12,14-17H2,1H3,(H,24,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D4 receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50294116 (CHEMBL561763 | N-[3-[4-(2-Methylsulfanylphenyl)pip...) Show SMILES CSc1ccccc1N1CCN(CCCNC(=O)c2cnn3ccccc23)CC1 Show InChI InChI=1S/C22H27N5OS/c1-29-21-9-3-2-8-20(21)26-15-13-25(14-16-26)11-6-10-23-22(28)18-17-24-27-12-5-4-7-19(18)27/h2-5,7-9,12,17H,6,10-11,13-16H2,1H3,(H,23,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D2L receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50102712 (2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50294117 (2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)H-pyr...) Show SMILES COc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C19H22N4O/c1-24-19-8-3-2-7-18(19)22-12-10-21(11-13-22)15-16-14-17-6-4-5-9-23(17)20-16/h2-9,14H,10-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D4 receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50119391 (CHEMBL142020 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccn3n2)CC1 Show InChI InChI=1S/C23H29N5O2/c1-30-22-10-3-2-9-21(22)27-16-14-26(15-17-27)12-7-5-11-24-23(29)20-18-19-8-4-6-13-28(19)25-20/h2-4,6,8-10,13,18H,5,7,11-12,14-17H2,1H3,(H,24,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50102712 (2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	6.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D4 receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50294116 (CHEMBL561763 | N-[3-[4-(2-Methylsulfanylphenyl)pip...) Show SMILES CSc1ccccc1N1CCN(CCCNC(=O)c2cnn3ccccc23)CC1 Show InChI InChI=1S/C22H27N5OS/c1-29-21-9-3-2-8-20(21)26-15-13-25(14-16-26)11-6-10-23-22(28)18-17-24-27-12-5-4-7-19(18)27/h2-5,7-9,12,17H,6,10-11,13-16H2,1H3,(H,23,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	8.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119375 (CHEMBL140612 | N-(3-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)c2cnn3ccccc23)CC1 Show InChI InChI=1S/C22H27N5O2/c1-29-21-9-3-2-8-20(21)26-15-13-25(14-16-26)11-6-10-23-22(28)18-17-24-27-12-5-4-7-19(18)27/h2-5,7-9,12,17H,6,10-11,13-16H2,1H3,(H,23,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50294116 (CHEMBL561763 | N-[3-[4-(2-Methylsulfanylphenyl)pip...) Show SMILES CSc1ccccc1N1CCN(CCCNC(=O)c2cnn3ccccc23)CC1 Show InChI InChI=1S/C22H27N5OS/c1-29-21-9-3-2-8-20(21)26-15-13-25(14-16-26)11-6-10-23-22(28)18-17-24-27-12-5-4-7-19(18)27/h2-5,7-9,12,17H,6,10-11,13-16H2,1H3,(H,23,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D4 receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119375 (CHEMBL140612 | N-(3-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)c2cnn3ccccc23)CC1 Show InChI InChI=1S/C22H27N5O2/c1-29-21-9-3-2-8-20(21)26-15-13-25(14-16-26)11-6-10-23-22(28)18-17-24-27-12-5-4-7-19(18)27/h2-5,7-9,12,17H,6,10-11,13-16H2,1H3,(H,23,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D2L receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50119375 (CHEMBL140612 | N-(3-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)c2cnn3ccccc23)CC1 Show InChI InChI=1S/C22H27N5O2/c1-29-21-9-3-2-8-20(21)26-15-13-25(14-16-26)11-6-10-23-22(28)18-17-24-27-12-5-4-7-19(18)27/h2-5,7-9,12,17H,6,10-11,13-16H2,1H3,(H,23,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50294115 (CHEMBL550222 | N-(4-(4-(2-(methylthio)phenyl)piper...) Show SMILES CSc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccn3n2)CC1 Show InChI InChI=1S/C23H29N5OS/c1-30-22-10-3-2-9-21(22)27-16-14-26(15-17-27)12-7-5-11-24-23(29)20-18-19-8-4-6-13-28(19)25-20/h2-4,6,8-10,13,18H,5,7,11-12,14-17H2,1H3,(H,24,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50294116 (CHEMBL561763 | N-[3-[4-(2-Methylsulfanylphenyl)pip...) Show SMILES CSc1ccccc1N1CCN(CCCNC(=O)c2cnn3ccccc23)CC1 Show InChI InChI=1S/C22H27N5OS/c1-29-21-9-3-2-8-20(21)26-15-13-25(14-16-26)11-6-10-23-22(28)18-17-24-27-12-5-4-7-19(18)27/h2-5,7-9,12,17H,6,10-11,13-16H2,1H3,(H,23,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D3 receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50294116 (CHEMBL561763 | N-[3-[4-(2-Methylsulfanylphenyl)pip...) Show SMILES CSc1ccccc1N1CCN(CCCNC(=O)c2cnn3ccccc23)CC1 Show InChI InChI=1S/C22H27N5OS/c1-29-21-9-3-2-8-20(21)26-15-13-25(14-16-26)11-6-10-23-22(28)18-17-24-27-12-5-4-7-19(18)27/h2-5,7-9,12,17H,6,10-11,13-16H2,1H3,(H,23,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50294115 (CHEMBL550222 | N-(4-(4-(2-(methylthio)phenyl)piper...) Show SMILES CSc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccn3n2)CC1 Show InChI InChI=1S/C23H29N5OS/c1-30-22-10-3-2-9-21(22)27-16-14-26(15-17-27)12-7-5-11-24-23(29)20-18-19-8-4-6-13-28(19)25-20/h2-4,6,8-10,13,18H,5,7,11-12,14-17H2,1H3,(H,24,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D2L receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50294118 (2-[5-[4-(4-Chlorophenyl)piperazin-1-yl]pentyl]pyra...) Show SMILES Clc1ccc(cc1)N1CCN(CCCCCc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C22H27ClN4/c23-19-8-10-21(11-9-19)26-16-14-25(15-17-26)12-4-1-2-6-20-18-22-7-3-5-13-27(22)24-20/h3,5,7-11,13,18H,1-2,4,6,12,14-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	46	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50119375 (CHEMBL140612 | N-(3-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)c2cnn3ccccc23)CC1 Show InChI InChI=1S/C22H27N5O2/c1-29-21-9-3-2-8-20(21)26-15-13-25(14-16-26)11-6-10-23-22(28)18-17-24-27-12-5-4-7-19(18)27/h2-5,7-9,12,17H,6,10-11,13-16H2,1H3,(H,23,28)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	56	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D4 receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50294115 (CHEMBL550222 | N-(4-(4-(2-(methylthio)phenyl)piper...) Show SMILES CSc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccn3n2)CC1 Show InChI InChI=1S/C23H29N5OS/c1-30-22-10-3-2-9-21(22)27-16-14-26(15-17-27)12-7-5-11-24-23(29)20-18-19-8-4-6-13-28(19)25-20/h2-4,6,8-10,13,18H,5,7,11-12,14-17H2,1H3,(H,24,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50119375 (CHEMBL140612 | N-(3-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)c2cnn3ccccc23)CC1 Show InChI InChI=1S/C22H27N5O2/c1-29-21-9-3-2-8-20(21)26-15-13-25(14-16-26)11-6-10-23-22(28)18-17-24-27-12-5-4-7-19(18)27/h2-5,7-9,12,17H,6,10-11,13-16H2,1H3,(H,23,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	69	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D3 receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(4) dopamine receptor (Homo sapiens (Human))	BDBM50119391 (CHEMBL142020 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccn3n2)CC1 Show InChI InChI=1S/C23H29N5O2/c1-30-22-10-3-2-9-21(22)27-16-14-26(15-17-27)12-7-5-11-24-23(29)20-18-19-8-4-6-13-28(19)25-20/h2-4,6,8-10,13,18H,5,7,11-12,14-17H2,1H3,(H,24,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	130	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D4 receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50119375 (CHEMBL140612 | N-(3-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCNC(=O)c2cnn3ccccc23)CC1 Show InChI InChI=1S/C22H27N5O2/c1-29-21-9-3-2-8-20(21)26-15-13-25(14-16-26)11-6-10-23-22(28)18-17-24-27-12-5-4-7-19(18)27/h2-5,7-9,12,17H,6,10-11,13-16H2,1H3,(H,23,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119391 (CHEMBL142020 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccn3n2)CC1 Show InChI InChI=1S/C23H29N5O2/c1-30-22-10-3-2-9-21(22)27-16-14-26(15-17-27)12-7-5-11-24-23(29)20-18-19-8-4-6-13-28(19)25-20/h2-4,6,8-10,13,18H,5,7,11-12,14-17H2,1H3,(H,24,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D2L receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50294115 (CHEMBL550222 | N-(4-(4-(2-(methylthio)phenyl)piper...) Show SMILES CSc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccn3n2)CC1 Show InChI InChI=1S/C23H29N5OS/c1-30-22-10-3-2-9-21(22)27-16-14-26(15-17-27)12-7-5-11-24-23(29)20-18-19-8-4-6-13-28(19)25-20/h2-4,6,8-10,13,18H,5,7,11-12,14-17H2,1H3,(H,24,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D3 receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50294118 (2-[5-[4-(4-Chlorophenyl)piperazin-1-yl]pentyl]pyra...) Show SMILES Clc1ccc(cc1)N1CCN(CCCCCc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C22H27ClN4/c23-19-8-10-21(11-9-19)26-16-14-25(15-17-26)12-4-1-2-6-20-18-22-7-3-5-13-27(22)24-20/h3,5,7-11,13,18H,1-2,4,6,12,14-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	160	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50294118 (2-[5-[4-(4-Chlorophenyl)piperazin-1-yl]pentyl]pyra...) Show SMILES Clc1ccc(cc1)N1CCN(CCCCCc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C22H27ClN4/c23-19-8-10-21(11-9-19)26-16-14-25(15-17-26)12-4-1-2-6-20-18-22-7-3-5-13-27(22)24-20/h3,5,7-11,13,18H,1-2,4,6,12,14-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D2L receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50294118 (2-[5-[4-(4-Chlorophenyl)piperazin-1-yl]pentyl]pyra...) Show SMILES Clc1ccc(cc1)N1CCN(CCCCCc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C22H27ClN4/c23-19-8-10-21(11-9-19)26-16-14-25(15-17-26)12-4-1-2-6-20-18-22-7-3-5-13-27(22)24-20/h3,5,7-11,13,18H,1-2,4,6,12,14-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D3 receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50294117 (2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)H-pyr...) Show SMILES COc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C19H22N4O/c1-24-19-8-3-2-7-18(19)22-12-10-21(11-13-22)15-16-14-17-6-4-5-9-23(17)20-16/h2-9,14H,10-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50119391 (CHEMBL142020 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccn3n2)CC1 Show InChI InChI=1S/C23H29N5O2/c1-30-22-10-3-2-9-21(22)27-16-14-26(15-17-27)12-7-5-11-24-23(29)20-18-19-8-4-6-13-28(19)25-20/h2-4,6,8-10,13,18H,5,7,11-12,14-17H2,1H3,(H,24,29)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50119391 (CHEMBL142020 | N-(4-(4-(2-methoxyphenyl)piperazin-...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2cc3ccccn3n2)CC1 Show InChI InChI=1S/C23H29N5O2/c1-30-22-10-3-2-9-21(22)27-16-14-26(15-17-27)12-7-5-11-24-23(29)20-18-19-8-4-6-13-28(19)25-20/h2-4,6,8-10,13,18H,5,7,11-12,14-17H2,1H3,(H,24,29)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	340	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D3 receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50294117 (2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)H-pyr...) Show SMILES COc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C19H22N4O/c1-24-19-8-3-2-7-18(19)22-12-10-21(11-13-22)15-16-14-17-6-4-5-9-23(17)20-16/h2-9,14H,10-13,15H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	350	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D2L receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50294118 (2-[5-[4-(4-Chlorophenyl)piperazin-1-yl]pentyl]pyra...) Show SMILES Clc1ccc(cc1)N1CCN(CCCCCc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C22H27ClN4/c23-19-8-10-21(11-9-19)26-16-14-25(15-17-26)12-4-1-2-6-20-18-22-7-3-5-13-27(22)24-20/h3,5,7-11,13,18H,1-2,4,6,12,14-17H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	370	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50294117 (2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)H-pyr...) Show SMILES COc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C19H22N4O/c1-24-19-8-3-2-7-18(19)22-12-10-21(11-13-22)15-16-14-17-6-4-5-9-23(17)20-16/h2-9,14H,10-13,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	770	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D3 receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50294117 (2-((4-(2-methoxyphenyl)piperazin-1-yl)methyl)H-pyr...) Show SMILES COc1ccccc1N1CCN(Cc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C19H22N4O/c1-24-19-8-3-2-7-18(19)22-12-10-21(11-13-22)15-16-14-17-6-4-5-9-23(17)20-16/h2-9,14H,10-13,15H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50102712 (2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D2L receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50102712 (2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	3.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D2L receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50102712 (2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from human cloned dopamine D3 receptor expressed in CHO cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50102712 (2-((4-(4-chlorophenyl)piperazin-1-yl)methyl)-pyraz...) Show SMILES Clc1ccc(cc1)N1CCN(Cc2cc3ccccn3n2)CC1 Show InChI InChI=1S/C18H19ClN4/c19-15-4-6-17(7-5-15)22-11-9-21(10-12-22)14-16-13-18-3-1-2-8-23(18)20-16/h1-8,13H,9-12,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem	Article PubMed	8.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Friedrich Alexander University Curated by ChEMBL					Assay Description Displacement of [3H]spiperone from wild type human cloned dopamine D3 receptor expressed in HEK293 cells				J Med Chem 52: 4923-35 (2009) Article DOI: 10.1021/jm900690y BindingDB Entry DOI: 10.7270/Q2PK0G5Q
					More data for this Ligand-Target Pair