Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Glutamate carboxypeptidase 2 (Homo sapiens (Human)) | BDBM50187704 (CHEMBL3828024) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea University Curated by ChEMBL | Assay Description Inhibition of PSMA (unknown origin) assessed as reduction in glutamate formation using NAAG as substrate preincubated for 30 mins followed by substra... | Eur J Med Chem 118: 208-218 (2016) Article DOI: 10.1016/j.ejmech.2016.04.033 BindingDB Entry DOI: 10.7270/Q2TX3HB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Glutamate carboxypeptidase 2 (Homo sapiens (Human)) | BDBM50187705 (CHEMBL3828668) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 28 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea University Curated by ChEMBL | Assay Description Inhibition of PSMA (unknown origin) assessed as reduction in glutamate formation using NAAG as substrate preincubated for 30 mins followed by substra... | Eur J Med Chem 118: 208-218 (2016) Article DOI: 10.1016/j.ejmech.2016.04.033 BindingDB Entry DOI: 10.7270/Q2TX3HB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease hepsin (Homo sapiens (Human)) | BDBM50106240 (6-Chloro-2-(2-hydroxy-biphenyl-3-yl)-1H-indole-5-c...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 2.60E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea University Curated by ChEMBL | Assay Description Inhibition of recombinant human hepsin using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Eur J Med Chem 118: 208-218 (2016) Article DOI: 10.1016/j.ejmech.2016.04.033 BindingDB Entry DOI: 10.7270/Q2TX3HB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease hepsin (Homo sapiens (Human)) | BDBM50187705 (CHEMBL3828668) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea University Curated by ChEMBL | Assay Description Inhibition of recombinant human hepsin using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Eur J Med Chem 118: 208-218 (2016) Article DOI: 10.1016/j.ejmech.2016.04.033 BindingDB Entry DOI: 10.7270/Q2TX3HB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease hepsin (Homo sapiens (Human)) | BDBM50187711 (CHEMBL3827463) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea University Curated by ChEMBL | Assay Description Inhibition of recombinant human hepsin using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Eur J Med Chem 118: 208-218 (2016) Article DOI: 10.1016/j.ejmech.2016.04.033 BindingDB Entry DOI: 10.7270/Q2TX3HB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease hepsin (Homo sapiens (Human)) | BDBM50187707 (CHEMBL3827292) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea University Curated by ChEMBL | Assay Description Inhibition of recombinant human hepsin using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Eur J Med Chem 118: 208-218 (2016) Article DOI: 10.1016/j.ejmech.2016.04.033 BindingDB Entry DOI: 10.7270/Q2TX3HB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease hepsin (Homo sapiens (Human)) | BDBM50187708 (CHEMBL3827374) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 8.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea University Curated by ChEMBL | Assay Description Inhibition of recombinant human hepsin using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Eur J Med Chem 118: 208-218 (2016) Article DOI: 10.1016/j.ejmech.2016.04.033 BindingDB Entry DOI: 10.7270/Q2TX3HB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease hepsin (Homo sapiens (Human)) | BDBM50187709 (CHEMBL3827645) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea University Curated by ChEMBL | Assay Description Inhibition of recombinant human hepsin using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Eur J Med Chem 118: 208-218 (2016) Article DOI: 10.1016/j.ejmech.2016.04.033 BindingDB Entry DOI: 10.7270/Q2TX3HB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease hepsin (Homo sapiens (Human)) | BDBM50187710 (CHEMBL3827788) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.10E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea University Curated by ChEMBL | Assay Description Inhibition of recombinant human hepsin using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Eur J Med Chem 118: 208-218 (2016) Article DOI: 10.1016/j.ejmech.2016.04.033 BindingDB Entry DOI: 10.7270/Q2TX3HB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease hepsin (Homo sapiens (Human)) | BDBM50187706 (CHEMBL3828589) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea University Curated by ChEMBL | Assay Description Inhibition of recombinant human hepsin using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Eur J Med Chem 118: 208-218 (2016) Article DOI: 10.1016/j.ejmech.2016.04.033 BindingDB Entry DOI: 10.7270/Q2TX3HB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease hepsin (Homo sapiens (Human)) | BDBM50187713 (CHEMBL3828730) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea University Curated by ChEMBL | Assay Description Inhibition of recombinant human hepsin using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Eur J Med Chem 118: 208-218 (2016) Article DOI: 10.1016/j.ejmech.2016.04.033 BindingDB Entry DOI: 10.7270/Q2TX3HB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease hepsin (Homo sapiens (Human)) | BDBM50102768 (2-(2-Hydroxy-phenyl)-1H-indole-5-carboxamidine | C...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 4.40E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea University Curated by ChEMBL | Assay Description Inhibition of recombinant human hepsin using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Eur J Med Chem 118: 208-218 (2016) Article DOI: 10.1016/j.ejmech.2016.04.033 BindingDB Entry DOI: 10.7270/Q2TX3HB6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine protease hepsin (Homo sapiens (Human)) | BDBM50187712 (CHEMBL3828185) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 7.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea University Curated by ChEMBL | Assay Description Inhibition of recombinant human hepsin using Boc-QAR-AMC as substrate preincubated for 30 mins followed by substrate addition by fluorescence assay | Eur J Med Chem 118: 208-218 (2016) Article DOI: 10.1016/j.ejmech.2016.04.033 BindingDB Entry DOI: 10.7270/Q2TX3HB6 | |||||||||||
More data for this Ligand-Target Pair |