BindingDB PrimarySearch

Found 8 hits Enz. Inhib. hit(s) with all data for entry = 50047761
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Steryl-sulfatase (Homo sapiens (Human))	BDBM50188235 (CHEMBL3827021) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Central University of Punjab Curated by ChEMBL					Assay Description Inhibition of placental sulphatase (unknown origin)				Eur J Med Chem 119: 141-68 (2016) Article DOI: 10.1016/j.ejmech.2016.03.087 BindingDB Entry DOI: 10.7270/Q29Z96V5
Central University of Punjab Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM9475 (4-(1H-Imidazol-1-ylmethyl)-7-phenoxy-2H-chromen-2-...) Show SMILES O=c1cc(Cn2ccnc2)c2ccc(Oc3ccccc3)cc2o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Central University of Punjab Curated by ChEMBL					Assay Description Inhibition of human placental microsomal aromatase using testosterone as substrate				Eur J Med Chem 119: 141-68 (2016) Article DOI: 10.1016/j.ejmech.2016.03.087 BindingDB Entry DOI: 10.7270/Q29Z96V5
Central University of Punjab Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM50180683 (CHEMBL3818720) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Central University of Punjab Curated by ChEMBL					Assay Description Inhibition of aromatase in human MCF7 cells using [1beta-3H]androstenedione as substrate measured after 1 hr by liquid scintillation counting method				Eur J Med Chem 119: 141-68 (2016) Article DOI: 10.1016/j.ejmech.2016.03.087 BindingDB Entry DOI: 10.7270/Q29Z96V5
Central University of Punjab Curated by ChEMBL					More data for this Ligand-Target Pair
Steryl-sulfatase (Homo sapiens (Human))	BDBM50188234 (CHEMBL269221) Show SMILES Cc1cc(=O)oc2ccc(OS(N)(=O)=O)cc12 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	380	n/a	n/a	n/a	n/a	n/a	n/a
Central University of Punjab Curated by ChEMBL					Assay Description Inhibition of sulphatase in human MCF7 cells assessed as inhibition of E1-STS activity				Eur J Med Chem 119: 141-68 (2016) Article DOI: 10.1016/j.ejmech.2016.03.087 BindingDB Entry DOI: 10.7270/Q29Z96V5
Central University of Punjab Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM23419 ((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central University of Punjab Curated by ChEMBL					Assay Description Inhibition of aromatase (unknown origin) preincubated for 10 mins in presence of NADPH generating system followed by addition of dibenzylfluorescein ...				Eur J Med Chem 119: 141-68 (2016) Article DOI: 10.1016/j.ejmech.2016.03.087 BindingDB Entry DOI: 10.7270/Q29Z96V5
Central University of Punjab Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM23419 ((2S)-5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
Central University of Punjab Curated by ChEMBL					Assay Description Inhibition of aromatase in human MCF7 cells using [1beta-3H]androstenedione as substrate measured after 1 hr by liquid scintillation counting method				Eur J Med Chem 119: 141-68 (2016) Article DOI: 10.1016/j.ejmech.2016.03.087 BindingDB Entry DOI: 10.7270/Q29Z96V5
Central University of Punjab Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM92557 (Neoflavonoid, 9) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central University of Punjab Curated by ChEMBL					Assay Description Inhibition of aromatase (unknown origin) preincubated for 10 mins in presence of NADPH generating system followed by addition of dibenzylfluorescein ...				Eur J Med Chem 119: 141-68 (2016) Article DOI: 10.1016/j.ejmech.2016.03.087 BindingDB Entry DOI: 10.7270/Q29Z96V5
Central University of Punjab Curated by ChEMBL					More data for this Ligand-Target Pair
Aromatase (Homo sapiens (Human))	BDBM92556 (Neoflavonoid, 8) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
Central University of Punjab Curated by ChEMBL					Assay Description Inhibition of aromatase (unknown origin) preincubated for 10 mins in presence of NADPH generating system followed by addition of dibenzylfluorescein ...				Eur J Med Chem 119: 141-68 (2016) Article DOI: 10.1016/j.ejmech.2016.03.087 BindingDB Entry DOI: 10.7270/Q29Z96V5
Central University of Punjab Curated by ChEMBL					More data for this Ligand-Target Pair