Compile Data Set for Download or QSAR

Found 44 hits Enz. Inhib. hit(s) with all data for entry = 50047773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Peregrin (Homo sapiens (Human))	BDBM50189403 (CHEMBL3828191) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N1CCNC[C@H]1C |r| Show InChI InChI=1S/C22H27N5O3/c1-14-13-23-9-10-27(14)17-12-19-18(25(2)22(29)26(19)3)11-16(17)24-21(28)15-7-5-6-8-20(15)30-4/h5-8,11-12,14,23H,9-10,13H2,1-4H3,(H,24,28)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of full length BRPF1 in human HUT78 cell nuclear/chromatin extract after 45 mins by chemoproteomic competition binding assay				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peregrin (Homo sapiens (Human))	BDBM50189392 (CHEMBL3828311) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N1CCC[C@H]1C |r| Show InChI InChI=1S/C22H26N4O3/c1-14-8-7-11-26(14)17-13-19-18(24(2)22(28)25(19)3)12-16(17)23-21(27)15-9-5-6-10-20(15)29-4/h5-6,9-10,12-14H,7-8,11H2,1-4H3,(H,23,27)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189403 (CHEMBL3828191) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N1CCNC[C@H]1C |r| Show InChI InChI=1S/C22H27N5O3/c1-14-13-23-9-10-27(14)17-12-19-18(25(2)22(29)26(19)3)11-16(17)24-21(28)15-7-5-6-8-20(15)30-4/h5-8,11-12,14,23H,9-10,13H2,1-4H3,(H,24,28)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peregrin (Homo sapiens (Human))	BDBM50189402 (CHEMBL3828008) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N1CCC[C@@H]1C |r| Show InChI InChI=1S/C22H26N4O3/c1-14-8-7-11-26(14)17-13-19-18(24(2)22(28)25(19)3)12-16(17)23-21(27)15-9-5-6-10-20(15)29-4/h5-6,9-10,12-14H,7-8,11H2,1-4H3,(H,23,27)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189403 (CHEMBL3828191) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N1CCNC[C@H]1C |r| Show InChI InChI=1S/C22H27N5O3/c1-14-13-23-9-10-27(14)17-12-19-18(25(2)22(29)26(19)3)11-16(17)24-21(28)15-7-5-6-8-20(15)30-4/h5-8,11-12,14,23H,9-10,13H2,1-4H3,(H,24,28)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity to NanoLuc-tagged BRPF1 isoform 1 bromodomain (625 to 735 residues) (unknown origin) expressed in HEK293 cells co-transfected with h...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peregrin (Homo sapiens (Human))	BDBM50189353 (CHEMBL3827767) Show SMILES COc1ncccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1OC(C)C Show InChI InChI=1S/C19H22N4O4/c1-11(2)27-16-10-15-14(22(3)19(25)23(15)4)9-13(16)21-17(24)12-7-6-8-20-18(12)26-5/h6-11H,1-5H3,(H,21,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189409 (CHEMBL3828684) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1OC(C)C Show InChI InChI=1S/C20H23N3O4/c1-12(2)27-18-11-16-15(22(3)20(25)23(16)4)10-14(18)21-19(24)13-8-6-7-9-17(13)26-5/h6-12H,1-5H3,(H,21,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189408 (CHEMBL3828194) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N(C)C Show InChI InChI=1S/C19H22N4O3/c1-21(2)14-11-16-15(22(3)19(25)23(16)4)10-13(14)20-18(24)12-8-6-7-9-17(12)26-5/h6-11H,1-5H3,(H,20,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50032927 (CHEMBL3356143 | N-[2,3-Dihydro-1,3-dimethyl-2-oxo-...) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N1CCCC1 Show InChI InChI=1S/C21H24N4O3/c1-23-17-12-15(22-20(26)14-8-4-5-9-19(14)28-3)16(25-10-6-7-11-25)13-18(17)24(2)21(23)27/h4-5,8-9,12-13H,6-7,10-11H2,1-3H3,(H,22,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peregrin (Homo sapiens (Human))	BDBM50189348 (CHEMBL3827114) Show SMILES CC(C)Oc1cc2n(C)c(=O)n(C)c2cc1NC(=O)c1ccccn1 Show InChI InChI=1S/C18H20N4O3/c1-11(2)25-16-10-15-14(21(3)18(24)22(15)4)9-13(16)20-17(23)12-7-5-6-8-19-12/h5-11H,1-4H3,(H,20,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189405 (CHEMBL3828354) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N1CCN[C@@H](C)C1 |r| Show InChI InChI=1S/C22H27N5O3/c1-14-13-27(10-9-23-14)17-12-19-18(25(2)22(29)26(19)3)11-16(17)24-21(28)15-7-5-6-8-20(15)30-4/h5-8,11-12,14,23H,9-10,13H2,1-4H3,(H,24,28)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189357 (CHEMBL3827560) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N1CCNCC1 Show InChI InChI=1S/C21H25N5O3/c1-24-17-12-15(23-20(27)14-6-4-5-7-19(14)29-3)16(26-10-8-22-9-11-26)13-18(17)25(2)21(24)28/h4-7,12-13,22H,8-11H2,1-3H3,(H,23,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	79	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189354 (CHEMBL3828061) Show SMILES COc1cccnc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1OC(C)C Show InChI InChI=1S/C19H22N4O4/c1-11(2)27-16-10-14-13(22(3)19(25)23(14)4)9-12(16)21-18(24)17-15(26-5)7-6-8-20-17/h6-11H,1-5H3,(H,21,24)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189339 (CHEMBL3828500) Show SMILES COCCOc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1OC(C)C Show InChI InChI=1S/C22H27N3O5/c1-14(2)30-20-13-18-17(24(3)22(27)25(18)4)12-16(20)23-21(26)15-8-6-7-9-19(15)29-11-10-28-5/h6-9,12-14H,10-11H2,1-5H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189340 (CHEMBL3828146) Show SMILES CC(C)Oc1cc2n(C)c(=O)n(C)c2cc1NC(=O)c1ccccc1OCC(=O)N(C)C Show InChI InChI=1S/C23H28N4O5/c1-14(2)32-20-12-18-17(26(5)23(30)27(18)6)11-16(20)24-22(29)15-9-7-8-10-19(15)31-13-21(28)25(3)4/h7-12,14H,13H2,1-6H3,(H,24,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189411 (CHEMBL3827996) Show SMILES CC(C)Oc1cc2n(C)c(=O)n(C)c2cc1NC(=O)c1ccccc1OCC(N)=O Show InChI InChI=1S/C21H24N4O5/c1-12(2)30-18-10-16-15(24(3)21(28)25(16)4)9-14(18)23-20(27)13-7-5-6-8-17(13)29-11-19(22)26/h5-10,12H,11H2,1-4H3,(H2,22,26)(H,23,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189406 (CHEMBL3827280) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N1CCN[C@H](C)C1 |r| Show InChI InChI=1S/C22H27N5O3/c1-14-13-27(10-9-23-14)17-12-19-18(25(2)22(29)26(19)3)11-16(17)24-21(28)15-7-5-6-8-20(15)30-4/h5-8,11-12,14,23H,9-10,13H2,1-4H3,(H,24,28)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50032928 (CHEMBL3356145) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1OC Show InChI InChI=1S/C18H19N3O4/c1-20-13-9-12(16(25-4)10-14(13)21(2)18(20)23)19-17(22)11-7-5-6-8-15(11)24-3/h5-10H,1-4H3,(H,19,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189351 (CHEMBL3827276) Show SMILES CC(C)Oc1cc2n(C)c(=O)n(C)c2cc1NC(=O)c1ccncn1 Show InChI InChI=1S/C17H19N5O3/c1-10(2)25-15-8-14-13(21(3)17(24)22(14)4)7-12(15)20-16(23)11-5-6-18-9-19-11/h5-10H,1-4H3,(H,20,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189410 (CHEMBL3828449) Show SMILES CC(C)Oc1cc2n(C)c(=O)n(C)c2cc1NC(=O)c1ccccc1OCCO Show InChI InChI=1S/C21H25N3O5/c1-13(2)29-19-12-17-16(23(3)21(27)24(17)4)11-15(19)22-20(26)14-7-5-6-8-18(14)28-10-9-25/h5-8,11-13,25H,9-10H2,1-4H3,(H,22,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189404 (CHEMBL3828026) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N1CCNC[C@@H]1C |r| Show InChI InChI=1S/C22H27N5O3/c1-14-13-23-9-10-27(14)17-12-19-18(25(2)22(29)26(19)3)11-16(17)24-21(28)15-7-5-6-8-20(15)30-4/h5-8,11-12,14,23H,9-10,13H2,1-4H3,(H,24,28)/t14-/m0/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189338 (CHEMBL3828399) Show SMILES CC(C)Oc1cc2n(C)c(=O)n(C)c2cc1NC(=O)c1ccccc1OCC#N Show InChI InChI=1S/C21H22N4O4/c1-13(2)29-19-12-17-16(24(3)21(27)25(17)4)11-15(19)23-20(26)14-7-5-6-8-18(14)28-10-9-22/h5-8,11-13H,10H2,1-4H3,(H,23,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189381 (CHEMBL3828504) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N1CCN(C)CC1 Show InChI InChI=1S/C22H27N5O3/c1-24-9-11-27(12-10-24)17-14-19-18(25(2)22(29)26(19)3)13-16(17)23-21(28)15-7-5-6-8-20(15)30-4/h5-8,13-14H,9-12H2,1-4H3,(H,23,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	200	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189341 (CHEMBL3827750) Show SMILES CC(C)Oc1cc2n(C)c(=O)n(C)c2cc1NC(=O)c1ccccc1OC1CCN(C)C1 Show InChI InChI=1S/C24H30N4O4/c1-15(2)31-22-13-20-19(27(4)24(30)28(20)5)12-18(22)25-23(29)17-8-6-7-9-21(17)32-16-10-11-26(3)14-16/h6-9,12-13,15-16H,10-11,14H2,1-5H3,(H,25,29)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189337 (CHEMBL3827554) Show SMILES CC(C)Oc1cc2n(C)c(=O)n(C)c2cc1NC(=O)c1ccccc1OCCN(C)C Show InChI InChI=1S/C23H30N4O4/c1-15(2)31-21-14-19-18(26(5)23(29)27(19)6)13-17(21)24-22(28)16-9-7-8-10-20(16)30-12-11-25(3)4/h7-10,13-15H,11-12H2,1-6H3,(H,24,28)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	316	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189347 (CHEMBL3827629) Show SMILES CC(C)Oc1cc2n(C)c(=O)n(C)c2cc1NC(=O)c1ccccc1 Show InChI InChI=1S/C19H21N3O3/c1-12(2)25-17-11-16-15(21(3)19(24)22(16)4)10-14(17)20-18(23)13-8-6-5-7-9-13/h5-12H,1-4H3,(H,20,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189345 (CHEMBL3828186) Show SMILES CC(C)Oc1cc2n(C)c(=O)n(C)c2cc1NC(=O)C1CCNC1 Show InChI InChI=1S/C17H24N4O3/c1-10(2)24-15-8-14-13(20(3)17(23)21(14)4)7-12(15)19-16(22)11-5-6-18-9-11/h7-8,10-11,18H,5-6,9H2,1-4H3,(H,19,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189350 (CHEMBL3828546) Show SMILES CC(C)Oc1cc2n(C)c(=O)n(C)c2cc1NC(=O)c1ccncc1 Show InChI InChI=1S/C18H20N4O3/c1-11(2)25-16-10-15-14(21(3)18(24)22(15)4)9-13(16)20-17(23)12-5-7-19-8-6-12/h5-11H,1-4H3,(H,20,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	794	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189407 (CHEMBL3827932) Show SMILES CCN(C(=O)c1ccccc1OC)c1cc2n(C)c(=O)n(C)c2cc1N1CCNC[C@H]1C |r| Show InChI InChI=1S/C24H31N5O3/c1-6-28(23(30)17-9-7-8-10-22(17)32-5)20-13-18-19(27(4)24(31)26(18)3)14-21(20)29-12-11-25-15-16(29)2/h7-10,13-14,16,25H,6,11-12,15H2,1-5H3/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Peregrin (Homo sapiens (Human))	BDBM50189343 (CHEMBL3828426) Show SMILES CC(C)Oc1cc2n(C)c(=O)n(C)c2cc1NC(C)=O Show InChI InChI=1S/C14H19N3O3/c1-8(2)20-13-7-12-11(6-10(13)15-9(3)18)16(4)14(19)17(12)5/h6-8H,1-5H3,(H,15,18)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189386 (CHEMBL3828357) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1C1=CCNCC1 |t:26| Show InChI InChI=1S/C22H24N4O3/c1-25-18-12-16(14-8-10-23-11-9-14)17(13-19(18)26(2)22(25)28)24-21(27)15-6-4-5-7-20(15)29-3/h4-8,12-13,23H,9-11H2,1-3H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189344 (CHEMBL3827710) Show SMILES CCCC(=O)Nc1cc2n(C)c(=O)n(C)c2cc1OC(C)C Show InChI InChI=1S/C16H23N3O3/c1-6-7-15(20)17-11-8-12-13(9-14(11)22-10(2)3)19(5)16(21)18(12)4/h8-10H,6-7H2,1-5H3,(H,17,20)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189349 (CHEMBL3827941) Show SMILES CC(C)Oc1cc2n(C)c(=O)n(C)c2cc1NC(=O)c1cccnc1 Show InChI InChI=1S/C18H20N4O3/c1-11(2)25-16-9-15-14(21(3)18(24)22(15)4)8-13(16)20-17(23)12-6-5-7-19-10-12/h5-11H,1-4H3,(H,20,23)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189356 (CHEMBL3827202) Show SMILES COc1ccccc1C(=O)Nc1cc2n(CCO)c(=O)n(C)c2cc1OC(C)C Show InChI InChI=1S/C21H25N3O5/c1-13(2)29-19-12-16-17(24(9-10-25)21(27)23(16)3)11-15(19)22-20(26)14-7-5-6-8-18(14)28-4/h5-8,11-13,25H,9-10H2,1-4H3,(H,22,26)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189346 (CHEMBL3827158) Show SMILES CC(C)Oc1cc2n(C)c(=O)n(C)c2cc1NC(=O)C1CCOCC1 Show InChI InChI=1S/C18H25N3O4/c1-11(2)25-16-10-15-14(20(3)18(23)21(15)4)9-13(16)19-17(22)12-5-7-24-8-6-12/h9-12H,5-8H2,1-4H3,(H,19,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50032925 (CHEMBL3356146) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1C Show InChI InChI=1S/C18H19N3O3/c1-11-9-14-15(21(3)18(23)20(14)2)10-13(11)19-17(22)12-7-5-6-8-16(12)24-4/h5-10H,1-4H3,(H,19,22)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189342 (CHEMBL3827927) Show SMILES CC(C)Oc1ccc2n(C)c(=O)n(C)c2c1 Show InChI InChI=1S/C12H16N2O2/c1-8(2)16-9-5-6-10-11(7-9)14(4)12(15)13(10)3/h5-8H,1-4H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.59E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189355 (CHEMBL3828299) Show SMILES COc1cccc(OC)c1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1OC(C)C Show InChI InChI=1S/C21H25N3O5/c1-12(2)29-18-11-15-14(23(3)21(26)24(15)4)10-13(18)22-20(25)19-16(27-5)8-7-9-17(19)28-6/h7-12H,1-6H3,(H,22,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189382 (CHEMBL3827434) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1C1CCNCC1 Show InChI InChI=1S/C22H26N4O3/c1-25-18-12-16(14-8-10-23-11-9-14)17(13-19(18)26(2)22(25)28)24-21(27)15-6-4-5-7-20(15)29-3/h4-7,12-14,23H,8-11H2,1-3H3,(H,24,27)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.16E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6H-Flag-TEV-BRPF1 (622 to 738 residues) (unknown origin) expressed in Esc...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189407 (CHEMBL3827932) Show SMILES CCN(C(=O)c1ccccc1OC)c1cc2n(C)c(=O)n(C)c2cc1N1CCNC[C@H]1C |r| Show InChI InChI=1S/C24H31N5O3/c1-6-28(23(30)17-9-7-8-10-22(17)32-5)20-13-18-19(27(4)24(31)26(18)3)14-21(20)29-12-11-25-15-16(29)2/h7-10,13-14,16,25H,6,11-12,15H2,1-5H3/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Binding affinity to NanoLuc-tagged BRPF1 isoform 1 bromodomain (625 to 735 residues) (unknown origin) expressed in HEK293 cells co-transfected with h...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Bromodomain-containing protein 1 (Homo sapiens (Human))	BDBM50189403 (CHEMBL3828191) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N1CCNC[C@H]1C |r| Show InChI InChI=1S/C22H27N5O3/c1-14-13-23-9-10-27(14)17-12-19-18(25(2)22(29)26(19)3)11-16(17)24-21(28)15-7-5-6-8-20(15)30-4/h5-8,11-12,14,23H,9-10,13H2,1-4H3,(H,24,28)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	7.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6HisFlag-Tev-BRPF2 (551 to 673 residues) (unknown origin) expressed in Es...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Bromodomain and PHD finger-containing protein 3 (Homo sapiens (Human))	BDBM50189403 (CHEMBL3828191) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N1CCNC[C@H]1C |r| Show InChI InChI=1S/C22H27N5O3/c1-14-13-23-9-10-27(14)17-12-19-18(25(2)22(29)26(19)3)11-16(17)24-21(28)15-7-5-6-8-20(15)30-4/h5-8,11-12,14,23H,9-10,13H2,1-4H3,(H,24,28)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6HisFlag-Tev-BRPF3 (579 to 706 residues) (unknown origin) expressed in Es...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Bromodomain-containing protein 1 (Homo sapiens (Human))	BDBM50189407 (CHEMBL3827932) Show SMILES CCN(C(=O)c1ccccc1OC)c1cc2n(C)c(=O)n(C)c2cc1N1CCNC[C@H]1C |r| Show InChI InChI=1S/C24H31N5O3/c1-6-28(23(30)17-9-7-8-10-22(17)32-5)20-13-18-19(27(4)24(31)26(18)3)14-21(20)29-12-11-25-15-16(29)2/h7-10,13-14,16,25H,6,11-12,15H2,1-5H3/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	5.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of synthetic fluorescent ligand binding to recombinant truncated 6HisFlag-Tev-BRPF2 (551 to 673 residues) (unknown origin) expressed in Es...				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair
Peregrin (Homo sapiens (Human))	BDBM50189403 (CHEMBL3828191) Show SMILES COc1ccccc1C(=O)Nc1cc2n(C)c(=O)n(C)c2cc1N1CCNC[C@H]1C |r| Show InChI InChI=1S/C22H27N5O3/c1-14-13-23-9-10-27(14)17-12-19-18(25(2)22(29)26(19)3)11-16(17)24-21(28)15-7-5-6-8-20(15)30-4/h5-8,11-12,14,23H,9-10,13H2,1-4H3,(H,24,28)/t14-/m1/s1	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	0.316	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Curated by ChEMBL					Assay Description Inhibition of human BRPF1 by BROMOscan assay				ACS Med Chem Lett 7: 552-7 (2016) Article DOI: 10.1021/acsmedchemlett.6b00092 BindingDB Entry DOI: 10.7270/Q2S184G2
					More data for this Ligand-Target Pair				3D Structure (crystal)