Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
17-beta-hydroxysteroid dehydrogenase 14 (Homo sapiens (Human)) | BDBM50189884 (CHEMBL3827618) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 7 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Philipps University Marburg Curated by ChEMBL | Assay Description Inhibition of human 17-beta-HSD14 using estradiol as substrate after 15 mins by fluorimetric assay | J Med Chem 59: 6961-7 (2016) Article DOI: 10.1021/acs.jmedchem.6b00293 BindingDB Entry DOI: 10.7270/Q2R213B7 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |