Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
N-lysine methyltransferase KMT5A (Homo sapiens (Human)) | BDBM50201571 (CHEMBL3934996) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | 50 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Competitive inhibition of human SETD8 (186 to 352 residues) using biotin-labeled H4K20 (1 to 24 residues) as substrate after 1 hr in presence of 3H-S... | ACS Med Chem Lett 7: 1102-1106 (2016) Article DOI: 10.1021/acsmedchemlett.6b00303 BindingDB Entry DOI: 10.7270/Q2319XVP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-lysine methyltransferase KMT5A (Homo sapiens (Human)) | BDBM50051116 (CHEMBL3318284) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Competitive inhibition of SETD8 (unknown origin) using biotin-labeled H4 (1 to 24 residues) as substrate after 1 hr in presence of varying levels of ... | ACS Med Chem Lett 7: 1102-1106 (2016) Article DOI: 10.1021/acsmedchemlett.6b00303 BindingDB Entry DOI: 10.7270/Q2319XVP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-lysine methyltransferase KMT5A (Homo sapiens (Human)) | BDBM50201571 (CHEMBL3934996) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 330 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Inhibition of human SETD8 (186 to 352 residues) using biotin-labeled H4K20 (1 to 24 residues) as substrate after 1 hr in presence of 3H-SAM by scinti... | ACS Med Chem Lett 7: 1102-1106 (2016) Article DOI: 10.1021/acsmedchemlett.6b00303 BindingDB Entry DOI: 10.7270/Q2319XVP | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
N-lysine methyltransferase KMT5A (Homo sapiens (Human)) | BDBM50051116 (CHEMBL3318284) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | 6.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
AbbVie Inc. Curated by ChEMBL | Assay Description Inhibition of SETD8 (unknown origin) using biotin-labeled H4 (1 to 24 residues) as substrate after 1 hr in presence of [3H]SAM by scintillation proxi... | ACS Med Chem Lett 7: 1102-1106 (2016) Article DOI: 10.1021/acsmedchemlett.6b00303 BindingDB Entry DOI: 10.7270/Q2319XVP | |||||||||||
More data for this Ligand-Target Pair |