Found 44 hits Enz. Inhib. hit(s) with all data for entry = 50030677 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300018
(2-(4-(Oxazol-5-yl)phenyl)-1H-benzo[d]imidazole-4-c...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1cnco1 Show InChI InChI=1S/C17H12N4O2/c18-16(22)12-2-1-3-13-15(12)21-17(20-13)11-6-4-10(5-7-11)14-8-19-9-23-14/h1-9H,(H2,18,22)(H,20,21) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 0.760 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300015
(2-(4-(Pyridin-3-yl)phenyl)-1H-benzo[d]imidazole-4-...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1cccnc1 Show InChI InChI=1S/C19H14N4O/c20-18(24)15-4-1-5-16-17(15)23-19(22-16)13-8-6-12(7-9-13)14-3-2-10-21-11-14/h1-11H,(H2,20,24)(H,22,23) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 0.950 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300008
(2-(4-(1,3,4-Oxadiazol-2-yl)phenyl)-1H-benzo[d]imid...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1nnco1 Show InChI InChI=1S/C16H11N5O2/c17-14(22)11-2-1-3-12-13(11)20-15(19-12)9-4-6-10(7-5-9)16-21-18-8-23-16/h1-8H,(H2,17,22)(H,19,20) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300019
(2-(4-(1H-Imidazol-5-yl)phenyl)-1H-benzo[d]imidazol...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1c[nH]cn1 Show InChI InChI=1S/C17H13N5O/c18-16(23)12-2-1-3-13-15(12)22-17(21-13)11-6-4-10(5-7-11)14-8-19-9-20-14/h1-9H,(H2,18,23)(H,19,20)(H,21,22) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300009
(2-(4-(5-Oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)pheny...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1n[nH]c(=O)o1 Show InChI InChI=1S/C16H11N5O3/c17-13(22)10-2-1-3-11-12(10)19-14(18-11)8-4-6-9(7-5-8)15-20-21-16(23)24-15/h1-7H,(H2,17,22)(H,18,19)(H,21,23) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300021
(2-(4-(Thiazol-4-yl)phenyl)-1H-benzo[d]imidazole-4-...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1cscn1 Show InChI InChI=1S/C17H12N4OS/c18-16(22)12-2-1-3-13-15(12)21-17(20-13)11-6-4-10(5-7-11)14-8-23-9-19-14/h1-9H,(H2,18,22)(H,20,21) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300016
(2-(4-(Pyridin-2-yl)phenyl)-1H-benzo[d]imidazole-4-...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1ccccn1 Show InChI InChI=1S/C19H14N4O/c20-18(24)14-4-3-6-16-17(14)23-19(22-16)13-9-7-12(8-10-13)15-5-1-2-11-21-15/h1-11H,(H2,20,24)(H,22,23) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 1.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300017
(2-(biphenyl-4-yl)-1H-benzo[d]imidazole-4-carboxami...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H15N3O/c21-19(24)16-7-4-8-17-18(16)23-20(22-17)15-11-9-14(10-12-15)13-5-2-1-3-6-13/h1-12H,(H2,21,24)(H,22,23) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| 2 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300020
(2-(4-(1H-Imidazol-2-yl)phenyl)-1H-benzo[d]imidazol...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1ncc[nH]1 Show InChI InChI=1S/C17H13N5O/c18-15(23)12-2-1-3-13-14(12)22-17(21-13)11-6-4-10(5-7-11)16-19-8-9-20-16/h1-9H,(H2,18,23)(H,19,20)(H,21,22) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300023
(2-(4-(2-Aminothiazol-4-yl)phenyl)-1H-benzo[d]imida...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1csc(N)n1 Show InChI InChI=1S/C17H13N5OS/c18-15(23)11-2-1-3-12-14(11)22-16(20-12)10-6-4-9(5-7-10)13-8-24-17(19)21-13/h1-8H,(H2,18,23)(H2,19,21)(H,20,22) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300022
(2-(4-(2-Methyloxazol-4-yl)phenyl)-1H-benzo[d]imida...)Show SMILES Cc1nc(co1)-c1ccc(cc1)-c1nc2c(cccc2[nH]1)C(N)=O Show InChI InChI=1S/C18H14N4O2/c1-10-20-15(9-24-10)11-5-7-12(8-6-11)18-21-14-4-2-3-13(17(19)23)16(14)22-18/h2-9H,1H3,(H2,19,23)(H,21,22) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 2.40 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300005
(2-(4-(Imidazo[1,2-a]pyridin-2-yl)phenyl)-1H-benzo[...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1cn2ccccc2n1 Show InChI InChI=1S/C21H15N5O/c22-20(27)15-4-3-5-16-19(15)25-21(24-16)14-9-7-13(8-10-14)17-12-26-11-2-1-6-18(26)23-17/h1-12H,(H2,22,27)(H,24,25) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 2.90 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300014
(2-(4-(Pyridin-4-yl)phenyl)-1H-benzimidazole-4-carb...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C19H14N4O/c20-18(24)15-2-1-3-16-17(15)23-19(22-16)14-6-4-12(5-7-14)13-8-10-21-11-9-13/h1-11H,(H2,20,24)(H,22,23) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300011
(2-(4-(5-Thioxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)ph...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1nc(=S)o[nH]1 Show InChI InChI=1S/C16H11N5O2S/c17-13(22)10-2-1-3-11-12(10)19-14(18-11)8-4-6-9(7-5-8)15-20-16(24)23-21-15/h1-7H,(H2,17,22)(H,18,19)(H,20,21,24) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 3.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300007
(2-(4-(3-Methyl-1,2,4-oxadiazol-5-yl)phenyl)-1H-ben...)Show SMILES Cc1noc(n1)-c1ccc(cc1)-c1nc2c(cccc2[nH]1)C(N)=O Show InChI InChI=1S/C17H13N5O2/c1-9-19-17(24-22-9)11-7-5-10(6-8-11)16-20-13-4-2-3-12(15(18)23)14(13)21-16/h2-8H,1H3,(H2,18,23)(H,20,21) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300013
(2-(4-(1-Methyl-1H-pyrazol-3-yl)phenyl)-1H-benzo[d]...)Show SMILES Cn1ccc(n1)-c1ccc(cc1)-c1nc2c(cccc2[nH]1)C(N)=O Show InChI InChI=1S/C18H15N5O/c1-23-10-9-14(22-23)11-5-7-12(8-6-11)18-20-15-4-2-3-13(17(19)24)16(15)21-18/h2-10H,1H3,(H2,19,24)(H,20,21) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 4.5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM27135
(2-[(2R)-2-methylpyrrolidin-2-yl]-1H-1,3-benzodiazo...)Show InChI InChI=1S/C13H16N4O/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17)/t13-/m1/s1 | PDB MMDB
UniProtKB/SwissProt
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Patents
Similars
| PDB Article PubMed
| 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300010
(2-(4-(5-Oxo-4,5-dihydro-1,2,4-thiadiazol-3-yl)phen...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1nc(=O)s[nH]1 Show InChI InChI=1S/C16H11N5O2S/c17-13(22)10-2-1-3-11-12(10)19-14(18-11)8-4-6-9(7-5-8)15-20-16(23)24-21-15/h1-7H,(H2,17,22)(H,18,19)(H,20,21,23) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 5.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300006
(2-(4-(7-(Trifluoromethyl)imidazo[1,2-a]pyridin-2-y...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1cn2ccc(cc2n1)C(F)(F)F Show InChI InChI=1S/C22H14F3N5O/c23-22(24,25)14-8-9-30-11-17(27-18(30)10-14)12-4-6-13(7-5-12)21-28-16-3-1-2-15(20(26)31)19(16)29-21/h1-11H,(H2,26,31)(H,28,29) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 6.80 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM27119
(2-(1-propylpiperidin-4-yl)-1H-1,3-benzodiazole-4-c...)Show InChI InChI=1S/C16H22N4O/c1-2-8-20-9-6-11(7-10-20)16-18-13-5-3-4-12(15(17)21)14(13)19-16/h3-5,11H,2,6-10H2,1H3,(H2,17,21)(H,18,19) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
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Similars
| PDB Article PubMed
| 8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300012
(2-(4-(Isoxazol-5-yl)phenyl)-1H-benzo[d]imidazole-4...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1ccno1 Show InChI InChI=1S/C17H12N4O2/c18-16(22)12-2-1-3-13-15(12)21-17(20-13)11-6-4-10(5-7-11)14-8-9-19-23-14/h1-9H,(H2,18,22)(H,20,21) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| 10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300025
(2-(4-(5-Oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)pheny...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1nc(=O)o[nH]1 Show InChI InChI=1S/C16H11N5O3/c17-13(22)10-2-1-3-11-12(10)19-14(18-11)8-4-6-9(7-5-8)15-20-16(23)24-21-15/h1-7H,(H2,17,22)(H,18,19)(H,20,21,23) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 16 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300024
(2-(4-(1H-Tetrazol-5-yl)phenyl)-1H-benzo[d]imidazol...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1nnn[nH]1 Show InChI InChI=1S/C15H11N7O/c16-13(23)10-2-1-3-11-12(10)18-14(17-11)8-4-6-9(7-5-8)15-19-21-22-20-15/h1-7H,(H2,16,23)(H,17,18)(H,19,20,21,22) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 by scintillation counting |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300022
(2-(4-(2-Methyloxazol-4-yl)phenyl)-1H-benzo[d]imida...)Show SMILES Cc1nc(co1)-c1ccc(cc1)-c1nc2c(cccc2[nH]1)C(N)=O Show InChI InChI=1S/C18H14N4O2/c1-10-20-15(9-24-10)11-5-7-12(8-6-11)18-21-14-4-2-3-13(17(19)23)16(14)22-18/h2-9H,1H3,(H2,19,23)(H,21,22) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 18 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300021
(2-(4-(Thiazol-4-yl)phenyl)-1H-benzo[d]imidazole-4-...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1cscn1 Show InChI InChI=1S/C17H12N4OS/c18-16(22)12-2-1-3-13-15(12)21-17(20-13)11-6-4-10(5-7-11)14-8-23-9-19-14/h1-9H,(H2,18,22)(H,20,21) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300020
(2-(4-(1H-Imidazol-2-yl)phenyl)-1H-benzo[d]imidazol...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1ncc[nH]1 Show InChI InChI=1S/C17H13N5O/c18-15(23)12-2-1-3-13-14(12)22-17(21-13)11-6-4-10(5-7-11)16-19-8-9-20-16/h1-9H,(H2,18,23)(H,19,20)(H,21,22) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 2.20 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300019
(2-(4-(1H-Imidazol-5-yl)phenyl)-1H-benzo[d]imidazol...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1c[nH]cn1 Show InChI InChI=1S/C17H13N5O/c18-16(23)12-2-1-3-13-15(12)22-17(21-13)11-6-4-10(5-7-11)14-8-19-9-20-14/h1-9H,(H2,18,23)(H,19,20)(H,21,22) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300018
(2-(4-(Oxazol-5-yl)phenyl)-1H-benzo[d]imidazole-4-c...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1cnco1 Show InChI InChI=1S/C17H12N4O2/c18-16(22)12-2-1-3-13-15(12)21-17(20-13)11-6-4-10(5-7-11)14-8-19-9-23-14/h1-9H,(H2,18,22)(H,20,21) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 0.990 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM27135
(2-[(2R)-2-methylpyrrolidin-2-yl]-1H-1,3-benzodiazo...)Show InChI InChI=1S/C13H16N4O/c1-13(6-3-7-15-13)12-16-9-5-2-4-8(11(14)18)10(9)17-12/h2,4-5,15H,3,6-7H2,1H3,(H2,14,18)(H,16,17)/t13-/m1/s1 | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MCE MMDB PC cid PC sid PDB UniChem
Patents
Similars
| PDB Article PubMed
| n/a | n/a | n/a | n/a | 2 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300017
(2-(biphenyl-4-yl)-1H-benzo[d]imidazole-4-carboxami...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C20H15N3O/c21-19(24)16-7-4-8-17-18(16)23-20(22-17)15-11-9-14(10-12-15)13-5-2-1-3-6-13/h1-12H,(H2,21,24)(H,22,23) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 71 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM27119
(2-(1-propylpiperidin-4-yl)-1H-1,3-benzodiazole-4-c...)Show InChI InChI=1S/C16H22N4O/c1-2-8-20-9-6-11(7-10-20)16-18-13-5-3-4-12(15(17)21)14(13)19-16/h3-5,11H,2,6-10H2,1H3,(H2,17,21)(H,18,19) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| Purchase
DrugBank MMDB PC cid PC sid PDB UniChem
Similars
| PDB Article PubMed
| n/a | n/a | n/a | n/a | 3 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | 3D Structure (crystal) |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300016
(2-(4-(Pyridin-2-yl)phenyl)-1H-benzo[d]imidazole-4-...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1ccccn1 Show InChI InChI=1S/C19H14N4O/c20-18(24)14-4-3-6-16-17(14)23-19(22-16)13-9-7-12(8-10-13)15-5-1-2-11-21-15/h1-11H,(H2,20,24)(H,22,23) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 7.80 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300015
(2-(4-(Pyridin-3-yl)phenyl)-1H-benzo[d]imidazole-4-...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1cccnc1 Show InChI InChI=1S/C19H14N4O/c20-18(24)15-4-1-5-16-17(15)23-19(22-16)13-8-6-12(7-9-13)14-3-2-10-21-11-14/h1-11H,(H2,20,24)(H,22,23) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 9 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300014
(2-(4-(Pyridin-4-yl)phenyl)-1H-benzimidazole-4-carb...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1ccncc1 Show InChI InChI=1S/C19H14N4O/c20-18(24)15-2-1-3-16-17(15)23-19(22-16)14-6-4-12(5-7-14)13-8-10-21-11-9-13/h1-11H,(H2,20,24)(H,22,23) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 12 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300013
(2-(4-(1-Methyl-1H-pyrazol-3-yl)phenyl)-1H-benzo[d]...)Show SMILES Cn1ccc(n1)-c1ccc(cc1)-c1nc2c(cccc2[nH]1)C(N)=O Show InChI InChI=1S/C18H15N5O/c1-23-10-9-14(22-23)11-5-7-12(8-6-11)18-20-15-4-2-3-13(17(19)24)16(15)21-18/h2-10H,1H3,(H2,19,24)(H,20,21) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300012
(2-(4-(Isoxazol-5-yl)phenyl)-1H-benzo[d]imidazole-4...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1ccno1 Show InChI InChI=1S/C17H12N4O2/c18-16(22)12-2-1-3-13-15(12)21-17(20-13)11-6-4-10(5-7-11)14-8-9-19-23-14/h1-9H,(H2,18,22)(H,20,21) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | >1.00E+3 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300011
(2-(4-(5-Thioxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)ph...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1nc(=S)o[nH]1 Show InChI InChI=1S/C16H11N5O2S/c17-13(22)10-2-1-3-11-12(10)19-14(18-11)8-4-6-9(7-5-8)15-20-16(24)23-21-15/h1-7H,(H2,17,22)(H,18,19)(H,20,21,24) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 328 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300010
(2-(4-(5-Oxo-4,5-dihydro-1,2,4-thiadiazol-3-yl)phen...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1nc(=O)s[nH]1 Show InChI InChI=1S/C16H11N5O2S/c17-13(22)10-2-1-3-11-12(10)19-14(18-11)8-4-6-9(7-5-8)15-20-16(23)24-21-15/h1-7H,(H2,17,22)(H,18,19)(H,20,21,23) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 461 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300009
(2-(4-(5-Oxo-4,5-dihydro-1,3,4-oxadiazol-2-yl)pheny...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1n[nH]c(=O)o1 Show InChI InChI=1S/C16H11N5O3/c17-13(22)10-2-1-3-11-12(10)19-14(18-11)8-4-6-9(7-5-8)15-20-21-16(23)24-15/h1-7H,(H2,17,22)(H,18,19)(H,21,23) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 64 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300008
(2-(4-(1,3,4-Oxadiazol-2-yl)phenyl)-1H-benzo[d]imid...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1nnco1 Show InChI InChI=1S/C16H11N5O2/c17-14(22)11-2-1-3-12-13(11)20-15(19-12)9-4-6-10(7-5-9)16-21-18-8-23-16/h1-8H,(H2,17,22)(H,19,20) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 3.70 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300007
(2-(4-(3-Methyl-1,2,4-oxadiazol-5-yl)phenyl)-1H-ben...)Show SMILES Cc1noc(n1)-c1ccc(cc1)-c1nc2c(cccc2[nH]1)C(N)=O Show InChI InChI=1S/C17H13N5O2/c1-9-19-17(24-22-9)11-7-5-10(6-8-11)16-20-13-4-2-3-12(15(18)23)14(13)21-16/h2-8H,1H3,(H2,18,23)(H,20,21) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | n/a | n/a | 9.10 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300023
(2-(4-(2-Aminothiazol-4-yl)phenyl)-1H-benzo[d]imida...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1csc(N)n1 Show InChI InChI=1S/C17H13N5OS/c18-15(23)11-2-1-3-12-14(11)22-16(20-12)10-6-4-9(5-7-10)13-8-24-17(19)21-13/h1-8H,(H2,18,23)(H2,19,21)(H,20,22) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 26 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300005
(2-(4-(Imidazo[1,2-a]pyridin-2-yl)phenyl)-1H-benzo[...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1cn2ccccc2n1 Show InChI InChI=1S/C21H15N5O/c22-20(27)15-4-3-5-16-19(15)25-21(24-16)14-9-7-13(8-10-14)17-12-26-11-2-1-6-18(26)23-17/h1-12H,(H2,22,27)(H,24,25) | PDB MMDB
UniProtKB/SwissProt
B.MOAD antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | n/a | n/a | 20 | n/a | n/a | n/a | n/a |
Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |
Poly [ADP-ribose] polymerase 1
(Homo sapiens (Human)) | BDBM50300006
(2-(4-(7-(Trifluoromethyl)imidazo[1,2-a]pyridin-2-y...)Show SMILES NC(=O)c1cccc2[nH]c(nc12)-c1ccc(cc1)-c1cn2ccc(cc2n1)C(F)(F)F Show InChI InChI=1S/C22H14F3N5O/c23-22(24,25)14-8-9-30-11-17(27-18(30)10-14)12-4-6-13(7-5-12)21-28-16-3-1-2-15(20(26)31)19(16)29-21/h1-11H,(H2,26,31)(H,28,29) | PDB MMDB
UniProtKB/SwissProt
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Abbott Laboratories
Curated by ChEMBL
| Assay Description Inhibition of PARP1 in human C41 cells after 30 mins by cell-based assay |
J Med Chem 52: 6803-13 (2009)
Article DOI: 10.1021/jm900697r BindingDB Entry DOI: 10.7270/Q2DN4548 |
More data for this Ligand-Target Pair | |