Compile Data Set for Download or QSAR

Found 93 hits Enz. Inhib. hit(s) with all data for entry = 50030742   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50268555 (6-(3-(furan-3-yl)benzylamino)-9-(3-hydroxypropyl)-...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccoc3)nc(nc12)C#N Show InChI InChI=1S/C20H18N6O2/c21-10-17-24-19(18-20(25-17)26(13-23-18)6-2-7-27)22-11-14-3-1-4-15(9-14)16-5-8-28-12-16/h1,3-5,8-9,12-13,27H,2,6-7,11H2,(H,22,24,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50300772 (6-(3-(1H-indol-5-yl)benzylamino)-9-(3-hydroxypropy...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccc4[nH]ccc4c3)nc(nc12)C#N Show InChI InChI=1S/C24H21N7O/c25-13-21-29-23(22-24(30-21)31(15-28-22)9-2-10-32)27-14-16-3-1-4-17(11-16)18-5-6-20-19(12-18)7-8-26-20/h1,3-8,11-12,15,26,32H,2,9-10,14H2,(H,27,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	190	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50268557 (9-(3-hydroxypropyl)-6-(3-(thiophen-3-yl)benzylamin...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccsc3)nc(nc12)C#N Show InChI InChI=1S/C20H18N6OS/c21-10-17-24-19(18-20(25-17)26(13-23-18)6-2-7-27)22-11-14-3-1-4-15(9-14)16-5-8-28-12-16/h1,3-5,8-9,12-13,27H,2,6-7,11H2,(H,22,24,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	240	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50268616 (9-(3-hydroxypropyl)-6-(3-(pyridin-3-yl)benzylamino...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3cccnc3)nc(nc12)C#N Show InChI InChI=1S/C21H19N7O/c22-11-18-26-20(19-21(27-18)28(14-25-19)8-3-9-29)24-12-15-4-1-5-16(10-15)17-6-2-7-23-13-17/h1-2,4-7,10,13-14,29H,3,8-9,12H2,(H,24,26,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50300773 (6-(3-(1H-indol-6-yl)benzylamino)-9-(3-hydroxypropy...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccc4cc[nH]c4c3)nc(nc12)C#N Show InChI InChI=1S/C24H21N7O/c25-13-21-29-23(22-24(30-21)31(15-28-22)9-2-10-32)27-14-16-3-1-4-18(11-16)19-6-5-17-7-8-26-20(17)12-19/h1,3-8,11-12,15,26,32H,2,9-10,14H2,(H,27,29,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50268554 (6-(3-(furan-2-yl)benzylamino)-9-(3-hydroxypropyl)-...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccco3)nc(nc12)C#N Show InChI InChI=1S/C20H18N6O2/c21-11-17-24-19(18-20(25-17)26(13-23-18)7-3-8-27)22-12-14-4-1-5-15(10-14)16-6-2-9-28-16/h1-2,4-6,9-10,13,27H,3,7-8,12H2,(H,22,24,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50300774 (CHEMBL570364 | N-(3'-((2-cyano-9-(3-hydroxypropyl)...) Show SMILES CC(=O)Nc1cccc(c1)-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1 Show InChI InChI=1S/C24H23N7O2/c1-16(33)28-20-8-3-7-19(12-20)18-6-2-5-17(11-18)14-26-23-22-24(30-21(13-25)29-23)31(15-27-22)9-4-10-32/h2-3,5-8,11-12,15,32H,4,9-10,14H2,1H3,(H,28,33)(H,26,29,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50300774 (CHEMBL570364 | N-(3'-((2-cyano-9-(3-hydroxypropyl)...) Show SMILES CC(=O)Nc1cccc(c1)-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1 Show InChI InChI=1S/C24H23N7O2/c1-16(33)28-20-8-3-7-19(12-20)18-6-2-5-17(11-18)14-26-23-22-24(30-21(13-25)29-23)31(15-27-22)9-4-10-32/h2-3,5-8,11-12,15,32H,4,9-10,14H2,1H3,(H,28,33)(H,26,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50300773 (6-(3-(1H-indol-6-yl)benzylamino)-9-(3-hydroxypropy...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccc4cc[nH]c4c3)nc(nc12)C#N Show InChI InChI=1S/C24H21N7O/c25-13-21-29-23(22-24(30-21)31(15-28-22)9-2-10-32)27-14-16-3-1-4-18(11-16)19-6-5-17-7-8-26-20(17)12-19/h1,3-8,11-12,15,26,32H,2,9-10,14H2,(H,27,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	460	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50268557 (9-(3-hydroxypropyl)-6-(3-(thiophen-3-yl)benzylamin...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccsc3)nc(nc12)C#N Show InChI InChI=1S/C20H18N6OS/c21-10-17-24-19(18-20(25-17)26(13-23-18)6-2-7-27)22-11-14-3-1-4-15(9-14)16-5-8-28-12-16/h1,3-5,8-9,12-13,27H,2,6-7,11H2,(H,22,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	480	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50268446 (CHEMBL496404 | methyl 3'-((2-cyano-9-(3-hydroxypro...) Show SMILES COC(=O)c1cccc(c1)-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1 Show InChI InChI=1S/C24H22N6O3/c1-33-24(32)19-8-3-7-18(12-19)17-6-2-5-16(11-17)14-26-22-21-23(29-20(13-25)28-22)30(15-27-21)9-4-10-31/h2-3,5-8,11-12,15,31H,4,9-10,14H2,1H3,(H,26,28,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50300772 (6-(3-(1H-indol-5-yl)benzylamino)-9-(3-hydroxypropy...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccc4[nH]ccc4c3)nc(nc12)C#N Show InChI InChI=1S/C24H21N7O/c25-13-21-29-23(22-24(30-21)31(15-28-22)9-2-10-32)27-14-16-3-1-4-17(11-16)18-5-6-20-19(12-18)7-8-26-20/h1,3-8,11-12,15,26,32H,2,9-10,14H2,(H,27,29,30)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	500	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50268555 (6-(3-(furan-3-yl)benzylamino)-9-(3-hydroxypropyl)-...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccoc3)nc(nc12)C#N Show InChI InChI=1S/C20H18N6O2/c21-10-17-24-19(18-20(25-17)26(13-23-18)6-2-7-27)22-11-14-3-1-4-15(9-14)16-5-8-28-12-16/h1,3-5,8-9,12-13,27H,2,6-7,11H2,(H,22,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50268553 (9-(3-hydroxypropyl)-6-(3-(naphthalen-2-yl)benzylam...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccc4ccccc4c3)nc(nc12)C#N Show InChI InChI=1S/C26H22N6O/c27-15-23-30-25(24-26(31-23)32(17-29-24)11-4-12-33)28-16-18-5-3-8-20(13-18)22-10-9-19-6-1-2-7-21(19)14-22/h1-3,5-10,13-14,17,33H,4,11-12,16H2,(H,28,30,31)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50300781 (6-((3'-chlorobiphenyl-3-yl)methylamino)-9-(3-hydro...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3cccc(Cl)c3)nc(nc12)C#N Show InChI InChI=1S/C22H19ClN6O/c23-18-7-2-6-17(11-18)16-5-1-4-15(10-16)13-25-21-20-22(28-19(12-24)27-21)29(14-26-20)8-3-9-30/h1-2,4-7,10-11,14,30H,3,8-9,13H2,(H,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50268668 (6-(biphenyl-3-ylmethylamino)-9-(3-hydroxypropyl)-9...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccccc3)nc(nc12)C#N Show InChI InChI=1S/C22H20N6O/c23-13-19-26-21(20-22(27-19)28(15-25-20)10-5-11-29)24-14-16-6-4-9-18(12-16)17-7-2-1-3-8-17/h1-4,6-9,12,15,29H,5,10-11,14H2,(H,24,26,27)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50268553 (9-(3-hydroxypropyl)-6-(3-(naphthalen-2-yl)benzylam...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccc4ccccc4c3)nc(nc12)C#N Show InChI InChI=1S/C26H22N6O/c27-15-23-30-25(24-26(31-23)32(17-29-24)11-4-12-33)28-16-18-5-3-8-20(13-18)22-10-9-19-6-1-2-7-21(19)14-22/h1-3,5-10,13-14,17,33H,4,11-12,16H2,(H,28,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50268500 (1-butyl-4-(2-(4'-ethylbiphenyl-3-yl)ethyl)-6-ethyn...) Show SMILES COc1ccc(cc1)-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1 Show InChI InChI=1S/C23H22N6O2/c1-31-19-8-6-17(7-9-19)18-5-2-4-16(12-18)14-25-22-21-23(28-20(13-24)27-22)29(15-26-21)10-3-11-30/h2,4-9,12,15,30H,3,10-11,14H2,1H3,(H,25,27,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50268446 (CHEMBL496404 | methyl 3'-((2-cyano-9-(3-hydroxypro...) Show SMILES COC(=O)c1cccc(c1)-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1 Show InChI InChI=1S/C24H22N6O3/c1-33-24(32)19-8-3-7-18(12-19)17-6-2-5-16(11-17)14-26-22-21-23(29-20(13-25)28-22)30(15-27-21)9-4-10-31/h2-3,5-8,11-12,15,31H,4,9-10,14H2,1H3,(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50268556 (9-(3-hydroxypropyl)-6-(3-(thiophen-2-yl)benzylamin...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3cccs3)nc(nc12)C#N Show InChI InChI=1S/C20H18N6OS/c21-11-17-24-19(18-20(25-17)26(13-23-18)7-3-8-27)22-12-14-4-1-5-15(10-14)16-6-2-9-28-16/h1-2,4-6,9-10,13,27H,3,7-8,12H2,(H,22,24,25)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50268668 (6-(biphenyl-3-ylmethylamino)-9-(3-hydroxypropyl)-9...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccccc3)nc(nc12)C#N Show InChI InChI=1S/C22H20N6O/c23-13-19-26-21(20-22(27-19)28(15-25-20)10-5-11-29)24-14-16-6-4-9-18(12-16)17-7-2-1-3-8-17/h1-4,6-9,12,15,29H,5,10-11,14H2,(H,24,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	800	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50268554 (6-(3-(furan-2-yl)benzylamino)-9-(3-hydroxypropyl)-...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccco3)nc(nc12)C#N Show InChI InChI=1S/C20H18N6O2/c21-11-17-24-19(18-20(25-17)26(13-23-18)7-3-8-27)22-12-14-4-1-5-15(10-14)16-6-2-9-28-16/h1-2,4-6,9-10,13,27H,3,7-8,12H2,(H,22,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	840	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50258405 (6-((3',4'-dichlorobiphenyl-3-yl)methylamino)-9-(3-...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccc(Cl)c(Cl)c3)nc(nc12)C#N Show InChI InChI=1S/C22H18Cl2N6O/c23-17-6-5-16(10-18(17)24)15-4-1-3-14(9-15)12-26-21-20-22(29-19(11-25)28-21)30(13-27-20)7-2-8-31/h1,3-6,9-10,13,31H,2,7-8,12H2,(H,26,28,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50268444 (6-((3'-(dimethylamino)biphenyl-3-yl)methylamino)-9...) Show SMILES CN(C)c1cccc(c1)-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1 Show InChI InChI=1S/C24H25N7O/c1-30(2)20-9-4-8-19(13-20)18-7-3-6-17(12-18)15-26-23-22-24(29-21(14-25)28-23)31(16-27-22)10-5-11-32/h3-4,6-9,12-13,16,32H,5,10-11,15H2,1-2H3,(H,26,28,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50258404 (6-((3',5'-dichlorobiphenyl-3-yl)methylamino)-9-(3-...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3cc(Cl)cc(Cl)c3)nc(nc12)C#N Show InChI InChI=1S/C22H18Cl2N6O/c23-17-8-16(9-18(24)10-17)15-4-1-3-14(7-15)12-26-21-20-22(29-19(11-25)28-21)30(13-27-20)5-2-6-31/h1,3-4,7-10,13,31H,2,5-6,12H2,(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50268556 (9-(3-hydroxypropyl)-6-(3-(thiophen-2-yl)benzylamin...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3cccs3)nc(nc12)C#N Show InChI InChI=1S/C20H18N6OS/c21-11-17-24-19(18-20(25-17)26(13-23-18)7-3-8-27)22-12-14-4-1-5-15(10-14)16-6-2-9-28-16/h1-2,4-6,9-10,13,27H,3,7-8,12H2,(H,22,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50300779 (9-(3-hydroxypropyl)-6-((2'-isopropylbiphenyl-3-yl)...) Show SMILES CC(C)c1ccccc1-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1 Show InChI InChI=1S/C25H26N6O/c1-17(2)20-9-3-4-10-21(20)19-8-5-7-18(13-19)15-27-24-23-25(30-22(14-26)29-24)31(16-28-23)11-6-12-32/h3-5,7-10,13,16-17,32H,6,11-12,15H2,1-2H3,(H,27,29,30)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	900	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50300784 (9-(3-hydroxypropyl)-6-(3-(1-(phenylsulfonyl)-1H-in...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3cn(c4ccccc34)S(=O)(=O)c3ccccc3)nc(nc12)C#N Show InChI InChI=1S/C30H25N7O3S/c31-17-27-34-29(28-30(35-27)36(20-33-28)14-7-15-38)32-18-21-8-6-9-22(16-21)25-19-37(26-13-5-4-12-24(25)26)41(39,40)23-10-2-1-3-11-23/h1-6,8-13,16,19-20,38H,7,14-15,18H2,(H,32,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50300778 (6-((2',6'-dimethylbiphenyl-3-yl)methylamino)-9-(3-...) Show SMILES Cc1cccc(C)c1-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1 Show InChI InChI=1S/C24H24N6O/c1-16-6-3-7-17(2)21(16)19-9-4-8-18(12-19)14-26-23-22-24(29-20(13-25)28-23)30(15-27-22)10-5-11-31/h3-4,6-9,12,15,31H,5,10-11,14H2,1-2H3,(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50268502 (9-(3-hydroxypropyl)-6-((4'-vinylbiphenyl-3-yl)meth...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccc(C=C)cc3)nc(nc12)C#N Show InChI InChI=1S/C24H22N6O/c1-2-17-7-9-19(10-8-17)20-6-3-5-18(13-20)15-26-23-22-24(29-21(14-25)28-23)30(16-27-22)11-4-12-31/h2-3,5-10,13,16,31H,1,4,11-12,15H2,(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50268500 (1-butyl-4-(2-(4'-ethylbiphenyl-3-yl)ethyl)-6-ethyn...) Show SMILES COc1ccc(cc1)-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1 Show InChI InChI=1S/C23H22N6O2/c1-31-19-8-6-17(7-9-19)18-5-2-4-16(12-18)14-25-22-21-23(28-20(13-24)27-22)29(15-26-21)10-3-11-30/h2,4-9,12,15,30H,3,10-11,14H2,1H3,(H,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50268670 (9-(3-hydroxypropyl)-6-((2'-methylbiphenyl-3-yl)met...) Show SMILES Cc1ccccc1-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1 Show InChI InChI=1S/C23H22N6O/c1-16-6-2-3-9-19(16)18-8-4-7-17(12-18)14-25-22-21-23(28-20(13-24)27-22)29(15-26-21)10-5-11-30/h2-4,6-9,12,15,30H,5,10-11,14H2,1H3,(H,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50258404 (6-((3',5'-dichlorobiphenyl-3-yl)methylamino)-9-(3-...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3cc(Cl)cc(Cl)c3)nc(nc12)C#N Show InChI InChI=1S/C22H18Cl2N6O/c23-17-8-16(9-18(24)10-17)15-4-1-3-14(7-15)12-26-21-20-22(29-19(11-25)28-21)30(13-27-20)5-2-6-31/h1,3-4,7-10,13,31H,2,5-6,12H2,(H,26,28,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50300781 (6-((3'-chlorobiphenyl-3-yl)methylamino)-9-(3-hydro...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3cccc(Cl)c3)nc(nc12)C#N Show InChI InChI=1S/C22H19ClN6O/c23-18-7-2-6-17(11-18)16-5-1-4-15(10-16)13-25-21-20-22(28-19(12-24)27-21)29(14-26-20)8-3-9-30/h1-2,4-7,10-11,14,30H,3,8-9,13H2,(H,25,27,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50300782 (CHEMBL571938 | methyl 3'-((2-cyano-9-(3-hydroxypro...) Show SMILES COC(=O)c1ccc(cc1)-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1 Show InChI InChI=1S/C24H22N6O3/c1-33-24(32)18-8-6-17(7-9-18)19-5-2-4-16(12-19)14-26-22-21-23(29-20(13-25)28-22)30(15-27-21)10-3-11-31/h2,4-9,12,15,31H,3,10-11,14H2,1H3,(H,26,28,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50268620 (6-((3'-bromo-2'-isopropoxybiphenyl-3-yl)methylamin...) Show SMILES CC(C)Oc1c(Br)cccc1-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1 Show InChI InChI=1S/C25H25BrN6O2/c1-16(2)34-23-19(8-4-9-20(23)26)18-7-3-6-17(12-18)14-28-24-22-25(31-21(13-27)30-24)32(15-29-22)10-5-11-33/h3-4,6-9,12,15-16,33H,5,10-11,14H2,1-2H3,(H,28,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50268445 (6-((4'-chlorobiphenyl-3-yl)methylamino)-9-(3-hydro...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccc(Cl)cc3)nc(nc12)C#N Show InChI InChI=1S/C22H19ClN6O/c23-18-7-5-16(6-8-18)17-4-1-3-15(11-17)13-25-21-20-22(28-19(12-24)27-21)29(14-26-20)9-2-10-30/h1,3-8,11,14,30H,2,9-10,13H2,(H,25,27,28)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50268444 (6-((3'-(dimethylamino)biphenyl-3-yl)methylamino)-9...) Show SMILES CN(C)c1cccc(c1)-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1 Show InChI InChI=1S/C24H25N7O/c1-30(2)20-9-4-8-19(13-20)18-7-3-6-17(12-18)15-26-23-22-24(29-21(14-25)28-23)31(16-27-22)10-5-11-32/h3-4,6-9,12-13,16,32H,5,10-11,15H2,1-2H3,(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50300780 (CHEMBL571276 | methyl 3'-((2-cyano-9-(3-hydroxypro...) Show SMILES COC(=O)c1ccccc1-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1 Show InChI InChI=1S/C24H22N6O3/c1-33-24(32)19-9-3-2-8-18(19)17-7-4-6-16(12-17)14-26-22-21-23(29-20(13-25)28-22)30(15-27-21)10-5-11-31/h2-4,6-9,12,15,31H,5,10-11,14H2,1H3,(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50268501 (9-(3-hydroxypropyl)-6-((3'-vinylbiphenyl-3-yl)meth...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3cccc(C=C)c3)nc(nc12)C#N Show InChI InChI=1S/C24H22N6O/c1-2-17-6-3-8-19(12-17)20-9-4-7-18(13-20)15-26-23-22-24(29-21(14-25)28-23)30(16-27-22)10-5-11-31/h2-4,6-9,12-13,16,31H,1,5,10-11,15H2,(H,26,28,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50300785 (9-(3-hydroxypropyl)-6-((2'-(trifluoromethyl)biphen...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccccc3C(F)(F)F)nc(nc12)C#N Show InChI InChI=1S/C23H19F3N6O/c24-23(25,26)18-8-2-1-7-17(18)16-6-3-5-15(11-16)13-28-21-20-22(31-19(12-27)30-21)32(14-29-20)9-4-10-33/h1-3,5-8,11,14,33H,4,9-10,13H2,(H,28,30,31)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50268501 (9-(3-hydroxypropyl)-6-((3'-vinylbiphenyl-3-yl)meth...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3cccc(C=C)c3)nc(nc12)C#N Show InChI InChI=1S/C24H22N6O/c1-2-17-6-3-8-19(12-17)20-9-4-7-18(13-20)15-26-23-22-24(29-21(14-25)28-23)30(16-27-22)10-5-11-31/h2-4,6-9,12-13,16,31H,1,5,10-11,15H2,(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50268620 (6-((3'-bromo-2'-isopropoxybiphenyl-3-yl)methylamin...) Show SMILES CC(C)Oc1c(Br)cccc1-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1 Show InChI InChI=1S/C25H25BrN6O2/c1-16(2)34-23-19(8-4-9-20(23)26)18-7-3-6-17(12-18)14-28-24-22-25(31-21(13-27)30-24)32(15-29-22)10-5-11-33/h3-4,6-9,12,15-16,33H,5,10-11,14H2,1-2H3,(H,28,30,31)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50268616 (9-(3-hydroxypropyl)-6-(3-(pyridin-3-yl)benzylamino...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3cccnc3)nc(nc12)C#N Show InChI InChI=1S/C21H19N7O/c22-11-18-26-20(19-21(27-18)28(14-25-19)8-3-9-29)24-12-15-4-1-5-16(10-15)17-6-2-7-23-13-17/h1-2,4-7,10,13-14,29H,3,8-9,12H2,(H,24,26,27)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50258405 (6-((3',4'-dichlorobiphenyl-3-yl)methylamino)-9-(3-...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccc(Cl)c(Cl)c3)nc(nc12)C#N Show InChI InChI=1S/C22H18Cl2N6O/c23-17-6-5-16(10-18(17)24)15-4-1-3-14(9-15)12-26-21-20-22(29-19(11-25)28-21)30(13-27-20)7-2-8-31/h1,3-6,9-10,13,31H,2,7-8,12H2,(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50300782 (CHEMBL571938 | methyl 3'-((2-cyano-9-(3-hydroxypro...) Show SMILES COC(=O)c1ccc(cc1)-c1cccc(CNc2nc(nc3n(CCCO)cnc23)C#N)c1 Show InChI InChI=1S/C24H22N6O3/c1-33-24(32)18-8-6-17(7-9-18)19-5-2-4-16(12-19)14-26-22-21-23(29-20(13-25)28-22)30(15-27-21)10-3-11-31/h2,4-9,12,15,31H,3,10-11,14H2,1H3,(H,26,28,29)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50268502 (9-(3-hydroxypropyl)-6-((4'-vinylbiphenyl-3-yl)meth...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccc(C=C)cc3)nc(nc12)C#N Show InChI InChI=1S/C24H22N6O/c1-2-17-7-9-19(10-8-17)20-6-3-5-18(13-20)15-26-23-22-24(29-21(14-25)28-23)30(16-27-22)11-4-12-31/h2-3,5-10,13,16,31H,1,4,11-12,15H2,(H,26,28,29)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50300783 (9-(3-hydroxypropyl)-6-(3-(1-(phenylsulfonyl)-1H-in...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3cc4ccccc4n3S(=O)(=O)c3ccccc3)nc(nc12)C#N Show InChI InChI=1S/C30H25N7O3S/c31-18-27-34-29(28-30(35-27)36(20-33-28)14-7-15-38)32-19-21-8-6-10-22(16-21)26-17-23-9-4-5-13-25(23)37(26)41(39,40)24-11-2-1-3-12-24/h1-6,8-13,16-17,20,38H,7,14-15,19H2,(H,32,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Procathepsin L (Homo sapiens (Human))	BDBM50268445 (6-((4'-chlorobiphenyl-3-yl)methylamino)-9-(3-hydro...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3ccc(Cl)cc3)nc(nc12)C#N Show InChI InChI=1S/C22H19ClN6O/c23-18-7-5-16(6-8-18)17-4-1-3-15(11-17)13-25-21-20-22(28-19(12-24)27-21)29(14-26-20)9-2-10-30/h1,3-8,11,14,30H,2,9-10,13H2,(H,25,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human liver cathepsin L				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair
Cysteine protease (Trypanosoma brucei rhodesiense)	BDBM50300784 (9-(3-hydroxypropyl)-6-(3-(1-(phenylsulfonyl)-1H-in...) Show SMILES OCCCn1cnc2c(NCc3cccc(c3)-c3cn(c4ccccc34)S(=O)(=O)c3ccccc3)nc(nc12)C#N Show InChI InChI=1S/C30H25N7O3S/c31-17-27-34-29(28-30(35-27)36(20-33-28)14-7-15-38)32-18-21-8-6-9-22(16-21)25-19-37(26-13-5-4-12-24(25)26)41(39,40)23-10-2-1-3-11-23/h1-6,8-13,16,19-20,38H,7,14-15,18H2,(H,32,34,35)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of Trypanosoma brucei rhodesiense rhodesain				J Med Chem 52: 6489-93 (2009) Article DOI: 10.1021/jm900908p BindingDB Entry DOI: 10.7270/Q2K074BP
					More data for this Ligand-Target Pair

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