Compile Data Set for Download or QSAR

Found 100 hits Enz. Inhib. hit(s) with all data for entry = 50048286   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50211599 (CHEMBL3986308) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccccc1[N+]([O-])=O Show InChI InChI=1S/C16H13N5O6S/c17-15-13(14(20-27-15)11-3-1-2-4-12(11)21(23)24)16(22)19-9-5-7-10(8-6-9)28(18,25)26/h1-8H,17H2,(H,19,22)(H2,18,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50211601 (CHEMBL3889623) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H13ClN4O4S/c17-10-3-1-9(2-4-10)14-13(15(18)25-21-14)16(22)20-11-5-7-12(8-6-11)26(19,23)24/h1-8H,18H2,(H,20,22)(H2,19,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50211600 (CHEMBL3907577) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C16H13N5O6S/c17-15-13(14(20-27-15)9-1-5-11(6-2-9)21(23)24)16(22)19-10-3-7-12(8-4-10)28(18,25)26/h1-8H,17H2,(H,19,22)(H2,18,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	0.800	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	2.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50211599 (CHEMBL3986308) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccccc1[N+]([O-])=O Show InChI InChI=1S/C16H13N5O6S/c17-15-13(14(20-27-15)11-3-1-2-4-12(11)21(23)24)16(22)19-9-5-7-10(8-6-9)28(18,25)26/h1-8H,17H2,(H,19,22)(H2,18,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50211603 (CHEMBL3916544) Show SMILES COc1cc(Cl)c(cc1OC)-c1noc(N)c1C(=O)Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H17ClN4O6S/c1-27-13-7-11(12(19)8-14(13)28-2)16-15(17(20)29-23-16)18(24)22-9-3-5-10(6-4-9)30(21,25)26/h3-8H,20H2,1-2H3,(H,22,24)(H2,21,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50211596 (CHEMBL3978103) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C16H14N4O4S/c17-15-13(14(20-24-15)10-4-2-1-3-5-10)16(21)19-11-6-8-12(9-7-11)25(18,22)23/h1-9H,17H2,(H,19,21)(H2,18,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50211593 (CHEMBL3925554) Show SMILES Nc1onc(-c2ccc(Cl)s2)c1C(=O)Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C14H11ClN4O4S2/c15-10-6-5-9(24-10)12-11(13(16)23-19-12)14(20)18-7-1-3-8(4-2-7)25(17,21)22/h1-6H,16H2,(H,18,20)(H2,17,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50211593 (CHEMBL3925554) Show SMILES Nc1onc(-c2ccc(Cl)s2)c1C(=O)Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C14H11ClN4O4S2/c15-10-6-5-9(24-10)12-11(13(16)23-19-12)14(20)18-7-1-3-8(4-2-7)25(17,21)22/h1-6H,16H2,(H,18,20)(H2,17,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50211644 (CHEMBL3917491) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C16H12Cl2N4O4S/c17-8-1-6-11(12(18)7-8)14-13(15(19)26-22-14)16(23)21-9-2-4-10(5-3-9)27(20,24)25/h1-7H,19H2,(H,21,23)(H2,20,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	6.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50211511 (CHEMBL3969743) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccc(F)cc1 Show InChI InChI=1S/C16H13FN4O4S/c17-10-3-1-9(2-4-10)14-13(15(18)25-21-14)16(22)20-11-5-7-12(8-6-11)26(19,23)24/h1-8H,18H2,(H,20,22)(H2,19,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50211596 (CHEMBL3978103) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccccc1 Show InChI InChI=1S/C16H14N4O4S/c17-15-13(14(20-24-15)10-4-2-1-3-5-10)16(21)19-11-6-8-12(9-7-11)25(18,22)23/h1-9H,17H2,(H,19,21)(H2,18,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50211601 (CHEMBL3889623) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H13ClN4O4S/c17-10-3-1-9(2-4-10)14-13(15(18)25-21-14)16(22)20-11-5-7-12(8-6-11)26(19,23)24/h1-8H,18H2,(H,20,22)(H2,19,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50211589 (CHEMBL3898548) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccc(Br)cc1 Show InChI InChI=1S/C16H13BrN4O4S/c17-10-3-1-9(2-4-10)14-13(15(18)25-21-14)16(22)20-11-5-7-12(8-6-11)26(19,23)24/h1-8H,18H2,(H,20,22)(H2,19,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50211603 (CHEMBL3916544) Show SMILES COc1cc(Cl)c(cc1OC)-c1noc(N)c1C(=O)Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H17ClN4O6S/c1-27-13-7-11(12(19)8-14(13)28-2)16-15(17(20)29-23-16)18(24)22-9-3-5-10(6-4-9)30(21,25)26/h3-8H,20H2,1-2H3,(H,22,24)(H2,21,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50211590 (CHEMBL3897472) Show SMILES Nc1onc(-c2ccc(Cl)o2)c1C(=O)Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C14H11ClN4O5S/c15-10-6-5-9(23-10)12-11(13(16)24-19-12)14(20)18-7-1-3-8(4-2-7)25(17,21)22/h1-6H,16H2,(H,18,20)(H2,17,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50211588 (CHEMBL3894919) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1c(Cl)cccc1Cl |(13.16,-14.5,;14.63,-14.96,;15.1,-16.42,;16.64,-16.42,;17.11,-14.95,;15.86,-14.06,;15.86,-12.52,;17.19,-11.75,;14.53,-11.76,;14.52,-10.22,;15.85,-9.45,;15.85,-7.91,;14.52,-7.14,;13.19,-7.91,;13.19,-9.45,;14.51,-5.6,;15.86,-4.83,;12.96,-5.6,;13.73,-4.26,;18.65,-14.95,;19.42,-13.62,;18.63,-12.28,;20.96,-13.61,;21.74,-14.95,;20.97,-16.29,;19.43,-16.29,;18.65,-17.63,)| Show InChI InChI=1S/C16H12Cl2N4O4S/c17-10-2-1-3-11(18)12(10)14-13(15(19)26-22-14)16(23)21-8-4-6-9(7-5-8)27(20,24)25/h1-7H,19H2,(H,21,23)(H2,20,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	8.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50211589 (CHEMBL3898548) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccc(Br)cc1 Show InChI InChI=1S/C16H13BrN4O4S/c17-10-3-1-9(2-4-10)14-13(15(18)25-21-14)16(22)20-11-5-7-12(8-6-11)26(19,23)24/h1-8H,18H2,(H,20,22)(H2,19,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50211600 (CHEMBL3907577) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C16H13N5O6S/c17-15-13(14(20-27-15)9-1-5-11(6-2-9)21(23)24)16(22)19-10-3-7-12(8-4-10)28(18,25)26/h1-8H,17H2,(H,19,22)(H2,18,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	9.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank MMDB PDB Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50211511 (CHEMBL3969743) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccc(F)cc1 Show InChI InChI=1S/C16H13FN4O4S/c17-10-3-1-9(2-4-10)14-13(15(18)25-21-14)16(22)20-11-5-7-12(8-6-11)26(19,23)24/h1-8H,18H2,(H,20,22)(H2,19,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50211595 (CHEMBL3918390) Show SMILES NS(=O)(=O)c1ccc(NC(=O)c2c(NC(=O)c3ccc(Br)cc3)onc2-c2c(Cl)cccc2Cl)cc1 |(15.83,-5.06,;14.49,-5.83,;12.94,-5.83,;13.71,-4.49,;14.49,-7.37,;15.82,-8.13,;15.83,-9.66,;14.5,-10.44,;14.5,-11.97,;15.83,-12.74,;17.16,-11.97,;15.84,-14.27,;14.6,-15.17,;13.14,-14.71,;11.99,-15.75,;12.32,-17.26,;10.52,-15.28,;10.19,-13.77,;8.72,-13.3,;7.57,-14.35,;6.1,-13.88,;7.91,-15.87,;9.39,-16.33,;15.08,-16.63,;16.62,-16.63,;17.08,-15.16,;18.62,-15.16,;19.38,-13.83,;18.6,-12.49,;20.92,-13.82,;21.7,-15.16,;20.94,-16.49,;19.39,-16.5,;18.62,-17.84,;13.17,-9.67,;13.17,-8.14,)| Show InChI InChI=1S/C23H15BrCl2N4O5S/c24-13-6-4-12(5-7-13)21(31)29-23-19(20(30-35-23)18-16(25)2-1-3-17(18)26)22(32)28-14-8-10-15(11-9-14)36(27,33)34/h1-11H,(H,28,32)(H,29,31)(H2,27,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50211644 (CHEMBL3917491) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C16H12Cl2N4O4S/c17-8-1-6-11(12(18)7-8)14-13(15(19)26-22-14)16(23)21-9-2-4-10(5-3-9)27(20,24)25/h1-7H,19H2,(H,21,23)(H2,20,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM50211601 (CHEMBL3889623) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1 Show InChI InChI=1S/C16H13ClN4O4S/c17-10-3-1-9(2-4-10)14-13(15(18)25-21-14)16(22)20-11-5-7-12(8-6-11)26(19,23)24/h1-8H,18H2,(H,20,22)(H2,19,23,24)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 4 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM50211603 (CHEMBL3916544) Show SMILES COc1cc(Cl)c(cc1OC)-c1noc(N)c1C(=O)Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C18H17ClN4O6S/c1-27-13-7-11(12(19)8-14(13)28-2)16-15(17(20)29-23-16)18(24)22-9-3-5-10(6-4-9)30(21,25)26/h3-8H,20H2,1-2H3,(H,22,24)(H2,21,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	47	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 4 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50211590 (CHEMBL3897472) Show SMILES Nc1onc(-c2ccc(Cl)o2)c1C(=O)Nc1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C14H11ClN4O5S/c15-10-6-5-9(23-10)12-11(13(16)24-19-12)14(20)18-7-1-3-8(4-2-7)25(17,21)22/h1-6H,16H2,(H,18,20)(H2,17,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM50211588 (CHEMBL3894919) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1c(Cl)cccc1Cl |(13.16,-14.5,;14.63,-14.96,;15.1,-16.42,;16.64,-16.42,;17.11,-14.95,;15.86,-14.06,;15.86,-12.52,;17.19,-11.75,;14.53,-11.76,;14.52,-10.22,;15.85,-9.45,;15.85,-7.91,;14.52,-7.14,;13.19,-7.91,;13.19,-9.45,;14.51,-5.6,;15.86,-4.83,;12.96,-5.6,;13.73,-4.26,;18.65,-14.95,;19.42,-13.62,;18.63,-12.28,;20.96,-13.61,;21.74,-14.95,;20.97,-16.29,;19.43,-16.29,;18.65,-17.63,)| Show InChI InChI=1S/C16H12Cl2N4O4S/c17-10-2-1-3-11(18)12(10)14-13(15(19)26-22-14)16(23)21-8-4-6-9(7-5-8)27(20,24)25/h1-7H,19H2,(H,21,23)(H2,20,24,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	50	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 1 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50211588 (CHEMBL3894919) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1c(Cl)cccc1Cl |(13.16,-14.5,;14.63,-14.96,;15.1,-16.42,;16.64,-16.42,;17.11,-14.95,;15.86,-14.06,;15.86,-12.52,;17.19,-11.75,;14.53,-11.76,;14.52,-10.22,;15.85,-9.45,;15.85,-7.91,;14.52,-7.14,;13.19,-7.91,;13.19,-9.45,;14.51,-5.6,;15.86,-4.83,;12.96,-5.6,;13.73,-4.26,;18.65,-14.95,;19.42,-13.62,;18.63,-12.28,;20.96,-13.61,;21.74,-14.95,;20.97,-16.29,;19.43,-16.29,;18.65,-17.63,)| Show InChI InChI=1S/C16H12Cl2N4O4S/c17-10-2-1-3-11(18)12(10)14-13(15(19)26-22-14)16(23)21-8-4-6-9(7-5-8)27(20,24)25/h1-7H,19H2,(H,21,23)(H2,20,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	52	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50211510 (CHEMBL3946274) Show SMILES NS(=O)(=O)c1ccc(NC(=O)c2c(NC(=O)c3ccc(Cl)cc3)onc2-c2ccc(Cl)cc2Cl)cc1 Show InChI InChI=1S/C23H15Cl3N4O5S/c24-13-3-1-12(2-4-13)21(31)29-23-19(20(30-35-23)17-10-5-14(25)11-18(17)26)22(32)28-15-6-8-16(9-7-15)36(27,33)34/h1-11H,(H,28,32)(H,29,31)(H2,27,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	55	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50211594 (CHEMBL3927339) Show SMILES NS(=O)(=O)c1ccc(NC(=O)c2c(NC(=O)c3ccc(Cl)cc3)onc2-c2c(Cl)cccc2Cl)cc1 |(15.83,-4.94,;14.49,-5.71,;12.94,-5.71,;13.71,-4.37,;14.49,-7.25,;15.82,-8.01,;15.83,-9.55,;14.5,-10.32,;14.5,-11.86,;15.83,-12.62,;17.16,-11.85,;15.84,-14.15,;14.6,-15.06,;13.14,-14.59,;11.99,-15.63,;12.32,-17.15,;10.52,-15.17,;10.19,-13.65,;8.72,-13.19,;7.57,-14.23,;6.1,-13.76,;7.91,-15.75,;9.39,-16.21,;15.08,-16.51,;16.62,-16.51,;17.08,-15.04,;18.62,-15.04,;19.38,-13.71,;18.6,-12.37,;20.92,-13.7,;21.7,-15.04,;20.94,-16.38,;19.39,-16.38,;18.62,-17.72,;13.17,-9.55,;13.17,-8.02,)| Show InChI InChI=1S/C23H15Cl3N4O5S/c24-13-6-4-12(5-7-13)21(31)29-23-19(20(30-35-23)18-16(25)2-1-3-17(18)26)22(32)28-14-8-10-15(11-9-14)36(27,33)34/h1-11H,(H,28,32)(H,29,31)(H2,27,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	58	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50211594 (CHEMBL3927339) Show SMILES NS(=O)(=O)c1ccc(NC(=O)c2c(NC(=O)c3ccc(Cl)cc3)onc2-c2c(Cl)cccc2Cl)cc1 |(15.83,-4.94,;14.49,-5.71,;12.94,-5.71,;13.71,-4.37,;14.49,-7.25,;15.82,-8.01,;15.83,-9.55,;14.5,-10.32,;14.5,-11.86,;15.83,-12.62,;17.16,-11.85,;15.84,-14.15,;14.6,-15.06,;13.14,-14.59,;11.99,-15.63,;12.32,-17.15,;10.52,-15.17,;10.19,-13.65,;8.72,-13.19,;7.57,-14.23,;6.1,-13.76,;7.91,-15.75,;9.39,-16.21,;15.08,-16.51,;16.62,-16.51,;17.08,-15.04,;18.62,-15.04,;19.38,-13.71,;18.6,-12.37,;20.92,-13.7,;21.7,-15.04,;20.94,-16.38,;19.39,-16.38,;18.62,-17.72,;13.17,-9.55,;13.17,-8.02,)| Show InChI InChI=1S/C23H15Cl3N4O5S/c24-13-6-4-12(5-7-13)21(31)29-23-19(20(30-35-23)18-16(25)2-1-3-17(18)26)22(32)28-14-8-10-15(11-9-14)36(27,33)34/h1-11H,(H,28,32)(H,29,31)(H2,27,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	62	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50211591 (CHEMBL3890026) Show SMILES NS(=O)(=O)c1ccc(NC(=O)c2c(NC(=O)c3ccc(Br)cc3)onc2-c2ccc(Cl)cc2Cl)cc1 Show InChI InChI=1S/C23H15BrCl2N4O5S/c24-13-3-1-12(2-4-13)21(31)29-23-19(20(30-35-23)17-10-5-14(25)11-18(17)26)22(32)28-15-6-8-16(9-7-15)36(27,33)34/h1-11H,(H,28,32)(H,29,31)(H2,27,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50211602 (CHEMBL3918052) Show SMILES COc1ccc(cc1)C(=O)Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1c(Cl)cccc1Cl |(4.95,-14.93,;6.1,-13.89,;7.57,-14.35,;8.72,-13.3,;10.19,-13.77,;10.52,-15.28,;9.39,-16.33,;7.91,-15.87,;11.99,-15.75,;12.32,-17.26,;13.14,-14.71,;14.6,-15.17,;15.08,-16.63,;16.62,-16.63,;17.08,-15.16,;15.84,-14.27,;15.83,-12.74,;17.16,-11.97,;14.5,-11.97,;14.5,-10.44,;15.83,-9.66,;15.82,-8.13,;14.49,-7.37,;13.17,-8.14,;13.17,-9.67,;14.49,-5.83,;15.83,-5.06,;12.94,-5.83,;13.71,-4.49,;18.62,-15.16,;19.38,-13.83,;18.6,-12.49,;20.92,-13.82,;21.7,-15.16,;20.94,-16.49,;19.39,-16.5,;18.62,-17.84,)| Show InChI InChI=1S/C24H18Cl2N4O6S/c1-35-15-9-5-13(6-10-15)22(31)29-24-20(21(30-36-24)19-17(25)3-2-4-18(19)26)23(32)28-14-7-11-16(12-8-14)37(27,33)34/h2-12H,1H3,(H,28,32)(H,29,31)(H2,27,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	67	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50211602 (CHEMBL3918052) Show SMILES COc1ccc(cc1)C(=O)Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1c(Cl)cccc1Cl |(4.95,-14.93,;6.1,-13.89,;7.57,-14.35,;8.72,-13.3,;10.19,-13.77,;10.52,-15.28,;9.39,-16.33,;7.91,-15.87,;11.99,-15.75,;12.32,-17.26,;13.14,-14.71,;14.6,-15.17,;15.08,-16.63,;16.62,-16.63,;17.08,-15.16,;15.84,-14.27,;15.83,-12.74,;17.16,-11.97,;14.5,-11.97,;14.5,-10.44,;15.83,-9.66,;15.82,-8.13,;14.49,-7.37,;13.17,-8.14,;13.17,-9.67,;14.49,-5.83,;15.83,-5.06,;12.94,-5.83,;13.71,-4.49,;18.62,-15.16,;19.38,-13.83,;18.6,-12.49,;20.92,-13.82,;21.7,-15.16,;20.94,-16.49,;19.39,-16.5,;18.62,-17.84,)| Show InChI InChI=1S/C24H18Cl2N4O6S/c1-35-15-9-5-13(6-10-15)22(31)29-24-20(21(30-36-24)19-17(25)3-2-4-18(19)26)23(32)28-14-7-11-16(12-8-14)37(27,33)34/h2-12H,1H3,(H,28,32)(H,29,31)(H2,27,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM50211602 (CHEMBL3918052) Show SMILES COc1ccc(cc1)C(=O)Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1c(Cl)cccc1Cl |(4.95,-14.93,;6.1,-13.89,;7.57,-14.35,;8.72,-13.3,;10.19,-13.77,;10.52,-15.28,;9.39,-16.33,;7.91,-15.87,;11.99,-15.75,;12.32,-17.26,;13.14,-14.71,;14.6,-15.17,;15.08,-16.63,;16.62,-16.63,;17.08,-15.16,;15.84,-14.27,;15.83,-12.74,;17.16,-11.97,;14.5,-11.97,;14.5,-10.44,;15.83,-9.66,;15.82,-8.13,;14.49,-7.37,;13.17,-8.14,;13.17,-9.67,;14.49,-5.83,;15.83,-5.06,;12.94,-5.83,;13.71,-4.49,;18.62,-15.16,;19.38,-13.83,;18.6,-12.49,;20.92,-13.82,;21.7,-15.16,;20.94,-16.49,;19.39,-16.5,;18.62,-17.84,)| Show InChI InChI=1S/C24H18Cl2N4O6S/c1-35-15-9-5-13(6-10-15)22(31)29-24-20(21(30-36-24)19-17(25)3-2-4-18(19)26)23(32)28-14-7-11-16(12-8-14)37(27,33)34/h2-12H,1H3,(H,28,32)(H,29,31)(H2,27,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 4 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 4 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair				3D Structure (crystal)
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50211509 (CHEMBL3979377) Show SMILES COc1ccc(cc1)C(=O)Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H18Cl2N4O6S/c1-35-16-7-2-13(3-8-16)22(31)29-24-20(21(30-36-24)18-11-4-14(25)12-19(18)26)23(32)28-15-5-9-17(10-6-15)37(27,33)34/h2-12H,1H3,(H,28,32)(H,29,31)(H2,27,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	77	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM50211510 (CHEMBL3946274) Show SMILES NS(=O)(=O)c1ccc(NC(=O)c2c(NC(=O)c3ccc(Cl)cc3)onc2-c2ccc(Cl)cc2Cl)cc1 Show InChI InChI=1S/C23H15Cl3N4O5S/c24-13-3-1-12(2-4-13)21(31)29-23-19(20(30-35-23)17-10-5-14(25)11-18(17)26)22(32)28-15-6-8-16(9-7-15)36(27,33)34/h1-11H,(H,28,32)(H,29,31)(H2,27,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 4 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50211509 (CHEMBL3979377) Show SMILES COc1ccc(cc1)C(=O)Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C24H18Cl2N4O6S/c1-35-16-7-2-13(3-8-16)22(31)29-24-20(21(30-36-24)18-11-4-14(25)12-19(18)26)23(32)28-15-5-9-17(10-6-15)37(27,33)34/h2-12H,1H3,(H,28,32)(H,29,31)(H2,27,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	86	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 7 (Homo sapiens (Human))	BDBM50211512 (CHEMBL3982616) Show SMILES NS(=O)(=O)c1ccc(NC(=O)c2c(NC(=O)c3ccc(cc3)[N+]([O-])=O)onc2-c2c(Cl)cccc2Cl)cc1 |(15.83,-4.82,;14.49,-5.59,;12.94,-5.59,;13.71,-4.25,;14.49,-7.13,;15.82,-7.9,;15.83,-9.43,;14.5,-10.21,;14.5,-11.74,;15.83,-12.5,;17.16,-11.73,;15.84,-14.04,;14.6,-14.94,;13.14,-14.47,;11.99,-15.52,;12.32,-17.03,;10.52,-15.05,;10.19,-13.54,;8.72,-13.07,;7.57,-14.11,;7.91,-15.63,;9.39,-16.09,;6.09,-13.65,;5.76,-12.13,;4.95,-14.69,;15.08,-16.4,;16.62,-16.39,;17.08,-14.93,;18.62,-14.92,;19.38,-13.59,;18.6,-12.26,;20.92,-13.58,;21.7,-14.92,;20.94,-16.26,;19.39,-16.26,;18.62,-17.6,;13.17,-9.43,;13.17,-7.9,)| Show InChI InChI=1S/C23H15Cl2N5O7S/c24-16-2-1-3-17(25)18(16)20-19(22(32)27-13-6-10-15(11-7-13)38(26,35)36)23(37-29-20)28-21(31)12-4-8-14(9-5-12)30(33)34/h1-11H,(H,27,32)(H,28,31)(H2,26,35,36)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	89	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 7 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM50211595 (CHEMBL3918390) Show SMILES NS(=O)(=O)c1ccc(NC(=O)c2c(NC(=O)c3ccc(Br)cc3)onc2-c2c(Cl)cccc2Cl)cc1 |(15.83,-5.06,;14.49,-5.83,;12.94,-5.83,;13.71,-4.49,;14.49,-7.37,;15.82,-8.13,;15.83,-9.66,;14.5,-10.44,;14.5,-11.97,;15.83,-12.74,;17.16,-11.97,;15.84,-14.27,;14.6,-15.17,;13.14,-14.71,;11.99,-15.75,;12.32,-17.26,;10.52,-15.28,;10.19,-13.77,;8.72,-13.3,;7.57,-14.35,;6.1,-13.88,;7.91,-15.87,;9.39,-16.33,;15.08,-16.63,;16.62,-16.63,;17.08,-15.16,;18.62,-15.16,;19.38,-13.83,;18.6,-12.49,;20.92,-13.82,;21.7,-15.16,;20.94,-16.49,;19.39,-16.5,;18.62,-17.84,;13.17,-9.67,;13.17,-8.14,)| Show InChI InChI=1S/C23H15BrCl2N4O5S/c24-13-6-4-12(5-7-13)21(31)29-23-19(20(30-35-23)18-16(25)2-1-3-17(18)26)22(32)28-14-8-10-15(11-9-14)36(27,33)34/h1-11H,(H,28,32)(H,29,31)(H2,27,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	108	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 4 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM50211644 (CHEMBL3917491) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C16H12Cl2N4O4S/c17-8-1-6-11(12(18)7-8)14-13(15(19)26-22-14)16(23)21-9-2-4-10(5-3-9)27(20,24)25/h1-7H,19H2,(H,21,23)(H2,20,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	Article PubMed	113	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 4 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM50211588 (CHEMBL3894919) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1c(Cl)cccc1Cl |(13.16,-14.5,;14.63,-14.96,;15.1,-16.42,;16.64,-16.42,;17.11,-14.95,;15.86,-14.06,;15.86,-12.52,;17.19,-11.75,;14.53,-11.76,;14.52,-10.22,;15.85,-9.45,;15.85,-7.91,;14.52,-7.14,;13.19,-7.91,;13.19,-9.45,;14.51,-5.6,;15.86,-4.83,;12.96,-5.6,;13.73,-4.26,;18.65,-14.95,;19.42,-13.62,;18.63,-12.28,;20.96,-13.61,;21.74,-14.95,;20.97,-16.29,;19.43,-16.29,;18.65,-17.63,)| Show InChI InChI=1S/C16H12Cl2N4O4S/c17-10-2-1-3-11(18)12(10)14-13(15(19)26-22-14)16(23)21-8-4-6-9(7-5-8)27(20,24)25/h1-7H,19H2,(H,21,23)(H2,20,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	146	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 4 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50211513 (CHEMBL3936291) Show SMILES NS(=O)(=O)c1ccc(NC(=O)c2c(NC(=O)c3ccccc3)onc2-c2c(Cl)cccc2Cl)cc1 |(15.83,-4.94,;14.49,-5.71,;12.94,-5.71,;13.71,-4.37,;14.49,-7.25,;15.82,-8.01,;15.83,-9.55,;14.5,-10.32,;14.5,-11.86,;15.83,-12.62,;17.16,-11.85,;15.84,-14.15,;14.6,-15.06,;13.14,-14.59,;11.99,-15.63,;12.32,-17.15,;10.52,-15.17,;10.19,-13.65,;8.72,-13.19,;7.57,-14.23,;7.91,-15.75,;9.39,-16.21,;15.08,-16.51,;16.62,-16.51,;17.08,-15.04,;18.62,-15.04,;19.39,-16.38,;18.62,-17.72,;20.94,-16.38,;21.7,-15.04,;20.92,-13.7,;19.38,-13.71,;18.6,-12.37,;13.17,-9.55,;13.17,-8.02,)| Show InChI InChI=1S/C23H16Cl2N4O5S/c24-16-7-4-8-17(25)18(16)20-19(22(31)27-14-9-11-15(12-10-14)35(26,32)33)23(34-29-20)28-21(30)13-5-2-1-3-6-13/h1-12H,(H,27,31)(H,28,30)(H2,26,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	151	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50211643 (CHEMBL3974625) Show SMILES NS(=O)(=O)c1ccc(NC(=O)c2c(NC(=O)c3ccc(cc3)[N+]([O-])=O)onc2-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C23H16FN5O7S/c24-15-5-1-13(2-6-15)20-19(22(31)26-16-7-11-18(12-8-16)37(25,34)35)23(36-28-20)27-21(30)14-3-9-17(10-4-14)29(32)33/h1-12H,(H,26,31)(H,27,30)(H2,25,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	168	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50211591 (CHEMBL3890026) Show SMILES NS(=O)(=O)c1ccc(NC(=O)c2c(NC(=O)c3ccc(Br)cc3)onc2-c2ccc(Cl)cc2Cl)cc1 Show InChI InChI=1S/C23H15BrCl2N4O5S/c24-13-3-1-12(2-4-13)21(31)29-23-19(20(30-35-23)17-10-5-14(25)11-18(17)26)22(32)28-15-6-8-16(9-7-15)36(27,33)34/h1-11H,(H,28,32)(H,29,31)(H2,27,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	188	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM50211594 (CHEMBL3927339) Show SMILES NS(=O)(=O)c1ccc(NC(=O)c2c(NC(=O)c3ccc(Cl)cc3)onc2-c2c(Cl)cccc2Cl)cc1 |(15.83,-4.94,;14.49,-5.71,;12.94,-5.71,;13.71,-4.37,;14.49,-7.25,;15.82,-8.01,;15.83,-9.55,;14.5,-10.32,;14.5,-11.86,;15.83,-12.62,;17.16,-11.85,;15.84,-14.15,;14.6,-15.06,;13.14,-14.59,;11.99,-15.63,;12.32,-17.15,;10.52,-15.17,;10.19,-13.65,;8.72,-13.19,;7.57,-14.23,;6.1,-13.76,;7.91,-15.75,;9.39,-16.21,;15.08,-16.51,;16.62,-16.51,;17.08,-15.04,;18.62,-15.04,;19.38,-13.71,;18.6,-12.37,;20.92,-13.7,;21.7,-15.04,;20.94,-16.38,;19.39,-16.38,;18.62,-17.72,;13.17,-9.55,;13.17,-8.02,)| Show InChI InChI=1S/C23H15Cl3N4O5S/c24-13-6-4-12(5-7-13)21(31)29-23-19(20(30-35-23)18-16(25)2-1-3-17(18)26)22(32)28-14-8-10-15(11-9-14)36(27,33)34/h1-11H,(H,28,32)(H,29,31)(H2,27,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	198	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 4 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 4 (Homo sapiens (Human))	BDBM50211599 (CHEMBL3986308) Show SMILES Nc1onc(c1C(=O)Nc1ccc(cc1)S(N)(=O)=O)-c1ccccc1[N+]([O-])=O Show InChI InChI=1S/C16H13N5O6S/c17-15-13(14(20-27-15)11-3-1-2-4-12(11)21(23)24)16(22)19-9-5-7-10(8-6-9)28(18,25)26/h1-8H,17H2,(H,19,22)(H2,18,25,26)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	246	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 4 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM50211508 (CHEMBL3954963) Show SMILES NS(=O)(=O)c1ccc(NC(=O)c2c(NC(=O)c3ccccc3)onc2-c2ccc(Cl)cc2Cl)cc1 Show InChI InChI=1S/C23H16Cl2N4O5S/c24-14-6-11-17(18(25)12-14)20-19(22(31)27-15-7-9-16(10-8-15)35(26,32)33)23(34-29-20)28-21(30)13-4-2-1-3-5-13/h1-12H,(H,27,31)(H,28,30)(H2,26,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	246	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 2 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair
Carbonic anhydrase 1 (Homo sapiens (Human))	BDBM10880 (AZA | AZA2 | AZM acetazolamide | Acerazolamide, AA...) Show SMILES CC(=O)Nc1nnc(s1)S(N)(=O)=O Show InChI InChI=1S/C4H6N4O3S2/c1-2(9)6-3-7-8-4(12-3)13(5,10)11/h1H3,(H2,5,10,11)(H,6,7,9)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	250	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abant Izzet Baysal University Curated by ChEMBL					Assay Description Inhibition of recombinant human carbonic anhydrase 1 assessed as reduction in CO2 hydration preincubated for 15 mins by stopped flow assay				Bioorg Med Chem 25: 1456-1464 (2017) Article DOI: 10.1016/j.bmc.2017.01.008 BindingDB Entry DOI: 10.7270/Q2MS3VXQ
					More data for this Ligand-Target Pair				3D Structure (crystal)

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