Compile Data Set for Download or QSAR

Found 84 hits Enz. Inhib. hit(s) with all data for entry = 50031233   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50309512 (2-(2,3-dichlorophenoxy)-3-(piperidin-4-yl)pyridine...) Show SMILES Clc1cccc(Oc2ncccc2C2CCNCC2)c1Cl Show InChI InChI=1S/C16H16Cl2N2O/c17-13-4-1-5-14(15(13)18)21-16-12(3-2-8-20-16)11-6-9-19-10-7-11/h1-5,8,11,19H,6-7,9-10H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50309515 (2-(2,4-dichlorophenoxy)-3-(piperidin-4-yl)pyridine...) Show SMILES Clc1ccc(Oc2ncccc2C2CCNCC2)c(Cl)c1 Show InChI InChI=1S/C16H16Cl2N2O/c17-12-3-4-15(14(18)10-12)21-16-13(2-1-7-20-16)11-5-8-19-9-6-11/h1-4,7,10-11,19H,5-6,8-9H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309523 (1-(2-(2-chloro-6-fluorophenoxy)pyridin-3-yl)pipera...) Show SMILES Fc1cccc(Cl)c1Oc1ncccc1N1CCNCC1 Show InChI InChI=1S/C15H15ClFN3O/c16-11-3-1-4-12(17)14(11)21-15-13(5-2-6-19-15)20-9-7-18-8-10-20/h1-6,18H,7-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309522 (1-(2-(2-chlorophenoxy)pyridin-3-yl)piperazine | CH...) Show SMILES Clc1ccccc1Oc1ncccc1N1CCNCC1 Show InChI InChI=1S/C15H16ClN3O/c16-12-4-1-2-6-14(12)20-15-13(5-3-7-18-15)19-10-8-17-9-11-19/h1-7,17H,8-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309505 (4-(2-fluoro-6-(2-fluorophenoxy)phenyl)piperidine |...) Show SMILES Fc1ccccc1Oc1cccc(F)c1C1CCNCC1 Show InChI InChI=1S/C17H17F2NO/c18-13-4-1-2-6-15(13)21-16-7-3-5-14(19)17(16)12-8-10-20-11-9-12/h1-7,12,20H,8-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309514 (2-(2-fluoro-4-methylphenoxy)-3-(piperidin-4-yl)pyr...) Show SMILES Cc1ccc(Oc2ncccc2C2CCNCC2)c(F)c1 Show InChI InChI=1S/C17H19FN2O/c1-12-4-5-16(15(18)11-12)21-17-14(3-2-8-20-17)13-6-9-19-10-7-13/h2-5,8,11,13,19H,6-7,9-10H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309520 (2-(2,6-difluorophenoxy)-3-(piperidin-4-yl)pyridine...) Show SMILES Fc1cccc(F)c1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C16H16F2N2O/c17-13-4-1-5-14(18)15(13)21-16-12(3-2-8-20-16)11-6-9-19-10-7-11/h1-5,8,11,19H,6-7,9-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309521 (2-(2-fluoro-6-methylphenoxy)-3-(piperidin-4-yl)pyr...) Show SMILES Cc1cccc(F)c1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C17H19FN2O/c1-12-4-2-6-15(18)16(12)21-17-14(5-3-9-20-17)13-7-10-19-11-8-13/h2-6,9,13,19H,7-8,10-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309519 (2-(2-chloro-6-fluorophenoxy)-3-(piperidin-4-yl)pyr...) Show SMILES Fc1cccc(Cl)c1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C16H16ClFN2O/c17-13-4-1-5-14(18)15(13)21-16-12(3-2-8-20-16)11-6-9-19-10-7-11/h1-5,8,11,19H,6-7,9-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309507 (2-(2-fluorophenoxy)-3-(piperidin-4-yl)pyridine | C...) Show SMILES Fc1ccccc1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C16H17FN2O/c17-14-5-1-2-6-15(14)20-16-13(4-3-9-19-16)12-7-10-18-11-8-12/h1-6,9,12,18H,7-8,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309508 (2-(2-chlorophenoxy)-3-(piperidin-4-yl)pyridine | C...) Show SMILES Clc1ccccc1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C16H17ClN2O/c17-14-5-1-2-6-15(14)20-16-13(4-3-9-19-16)12-7-10-18-11-8-12/h1-6,9,12,18H,7-8,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309517 (2-(2-chloro-5-fluorophenoxy)-3-(piperidin-4-yl)pyr...) Show SMILES Fc1ccc(Cl)c(Oc2ncccc2C2CCNCC2)c1 Show InChI InChI=1S/C16H16ClFN2O/c17-14-4-3-12(18)10-15(14)21-16-13(2-1-7-20-16)11-5-8-19-9-6-11/h1-4,7,10-11,19H,5-6,8-9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309518 (2-(2-fluoro-6-methoxyphenoxy)-3-(piperidin-4-yl)py...) Show SMILES COc1cccc(F)c1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C17H19FN2O2/c1-21-15-6-2-5-14(18)16(15)22-17-13(4-3-9-20-17)12-7-10-19-11-8-12/h2-6,9,12,19H,7-8,10-11H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50309512 (2-(2,3-dichlorophenoxy)-3-(piperidin-4-yl)pyridine...) Show SMILES Clc1cccc(Oc2ncccc2C2CCNCC2)c1Cl Show InChI InChI=1S/C16H16Cl2N2O/c17-13-4-1-5-14(15(13)18)21-16-12(3-2-8-20-16)11-6-9-19-10-7-11/h1-5,8,11,19H,6-7,9-10H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	25	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50309521 (2-(2-fluoro-6-methylphenoxy)-3-(piperidin-4-yl)pyr...) Show SMILES Cc1cccc(F)c1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C17H19FN2O/c1-12-4-2-6-15(18)16(12)21-17-14(5-3-9-20-17)13-7-10-19-11-8-13/h2-6,9,13,19H,7-8,10-11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	27	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309516 (2-(2,4-difluorophenoxy)-3-(piperidin-4-yl)pyridine...) Show SMILES Fc1ccc(Oc2ncccc2C2CCNCC2)c(F)c1 Show InChI InChI=1S/C16H16F2N2O/c17-12-3-4-15(14(18)10-12)21-16-13(2-1-7-20-16)11-5-8-19-9-6-11/h1-4,7,10-11,19H,5-6,8-9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	29	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50309516 (2-(2,4-difluorophenoxy)-3-(piperidin-4-yl)pyridine...) Show SMILES Fc1ccc(Oc2ncccc2C2CCNCC2)c(F)c1 Show InChI InChI=1S/C16H16F2N2O/c17-12-3-4-15(14(18)10-12)21-16-13(2-1-7-20-16)11-5-8-19-9-6-11/h1-4,7,10-11,19H,5-6,8-9H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50309505 (4-(2-fluoro-6-(2-fluorophenoxy)phenyl)piperidine |...) Show SMILES Fc1ccccc1Oc1cccc(F)c1C1CCNCC1 Show InChI InChI=1S/C17H17F2NO/c18-13-4-1-2-6-15(13)21-16-7-3-5-14(19)17(16)12-8-10-20-11-9-12/h1-7,12,20H,8-11H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	32	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50309519 (2-(2-chloro-6-fluorophenoxy)-3-(piperidin-4-yl)pyr...) Show SMILES Fc1cccc(Cl)c1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C16H16ClFN2O/c17-13-4-1-5-14(18)15(13)21-16-12(3-2-8-20-16)11-6-9-19-10-7-11/h1-5,8,11,19H,6-7,9-10H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50309514 (2-(2-fluoro-4-methylphenoxy)-3-(piperidin-4-yl)pyr...) Show SMILES Cc1ccc(Oc2ncccc2C2CCNCC2)c(F)c1 Show InChI InChI=1S/C17H19FN2O/c1-12-4-5-16(15(18)11-12)21-17-14(3-2-8-20-17)13-6-9-19-10-7-13/h2-5,8,11,13,19H,6-7,9-10H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	36	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309512 (2-(2,3-dichlorophenoxy)-3-(piperidin-4-yl)pyridine...) Show SMILES Clc1cccc(Oc2ncccc2C2CCNCC2)c1Cl Show InChI InChI=1S/C16H16Cl2N2O/c17-13-4-1-5-14(15(13)18)21-16-12(3-2-8-20-16)11-6-9-19-10-7-11/h1-5,8,11,19H,6-7,9-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309515 (2-(2,4-dichlorophenoxy)-3-(piperidin-4-yl)pyridine...) Show SMILES Clc1ccc(Oc2ncccc2C2CCNCC2)c(Cl)c1 Show InChI InChI=1S/C16H16Cl2N2O/c17-12-3-4-15(14(18)10-12)21-16-13(2-1-7-20-16)11-5-8-19-9-6-11/h1-4,7,10-11,19H,5-6,8-9H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	37	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50309508 (2-(2-chlorophenoxy)-3-(piperidin-4-yl)pyridine | C...) Show SMILES Clc1ccccc1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C16H17ClN2O/c17-14-5-1-2-6-15(14)20-16-13(4-3-9-19-16)12-7-10-18-11-8-12/h1-6,9,12,18H,7-8,10-11H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	57	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309510 (3-(piperidin-4-yl)-2-(o-tolyloxy)pyridine | CHEMBL...) Show SMILES Cc1ccccc1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C17H20N2O/c1-13-5-2-3-7-16(13)20-17-15(6-4-10-19-17)14-8-11-18-12-9-14/h2-7,10,14,18H,8-9,11-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309511 (3-(piperidin-4-yl)-2-(2-(trifluoromethyl)phenoxy)p...) Show SMILES FC(F)(F)c1ccccc1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C17H17F3N2O/c18-17(19,20)14-5-1-2-6-15(14)23-16-13(4-3-9-22-16)12-7-10-21-11-8-12/h1-6,9,12,21H,7-8,10-11H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	71	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50309508 (2-(2-chlorophenoxy)-3-(piperidin-4-yl)pyridine | C...) Show SMILES Clc1ccccc1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C16H17ClN2O/c17-14-5-1-2-6-15(14)20-16-13(4-3-9-19-16)12-7-10-18-11-8-12/h1-6,9,12,18H,7-8,10-11H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	74	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309509 (2-(2-methoxyphenoxy)-3-(piperidin-4-yl)pyridine | ...) Show SMILES COc1ccccc1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C17H20N2O2/c1-20-15-6-2-3-7-16(15)21-17-14(5-4-10-19-17)13-8-11-18-12-9-13/h2-7,10,13,18H,8-9,11-12H2,1H3	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309506 (2-phenoxy-3-(piperidin-4-yl)pyridine | CHEMBL60814...) Show SMILES C1CC(CCN1)c1cccnc1Oc1ccccc1 Show InChI InChI=1S/C16H18N2O/c1-2-5-14(6-3-1)19-16-15(7-4-10-18-16)13-8-11-17-12-9-13/h1-7,10,13,17H,8-9,11-12H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	101	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50309521 (2-(2-fluoro-6-methylphenoxy)-3-(piperidin-4-yl)pyr...) Show SMILES Cc1cccc(F)c1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C17H19FN2O/c1-12-4-2-6-15(18)16(12)21-17-14(5-3-9-20-17)13-7-10-19-11-8-13/h2-6,9,13,19H,7-8,10-11H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	102	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50309513 (2-(2,3-difluorophenoxy)-3-(piperidin-4-yl)pyridine...) Show SMILES Fc1cccc(Oc2ncccc2C2CCNCC2)c1F Show InChI InChI=1S/C16H16F2N2O/c17-13-4-1-5-14(15(13)18)21-16-12(3-2-8-20-16)11-6-9-19-10-7-11/h1-5,8,11,19H,6-7,9-10H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	109	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50309511 (3-(piperidin-4-yl)-2-(2-(trifluoromethyl)phenoxy)p...) Show SMILES FC(F)(F)c1ccccc1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C17H17F3N2O/c18-17(19,20)14-5-1-2-6-15(14)23-16-13(4-3-9-22-16)12-7-10-21-11-8-12/h1-6,9,12,21H,7-8,10-11H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50309516 (2-(2,4-difluorophenoxy)-3-(piperidin-4-yl)pyridine...) Show SMILES Fc1ccc(Oc2ncccc2C2CCNCC2)c(F)c1 Show InChI InChI=1S/C16H16F2N2O/c17-12-3-4-15(14(18)10-12)21-16-13(2-1-7-20-16)11-5-8-19-9-6-11/h1-4,7,10-11,19H,5-6,8-9H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	143	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50309513 (2-(2,3-difluorophenoxy)-3-(piperidin-4-yl)pyridine...) Show SMILES Fc1cccc(Oc2ncccc2C2CCNCC2)c1F Show InChI InChI=1S/C16H16F2N2O/c17-13-4-1-5-14(15(13)18)21-16-12(3-2-8-20-16)11-6-9-19-10-7-11/h1-5,8,11,19H,6-7,9-10H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	173	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]8-OH-DPAT from human cloned 5HT1A receptor by filtration techniques				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50309520 (2-(2,6-difluorophenoxy)-3-(piperidin-4-yl)pyridine...) Show SMILES Fc1cccc(F)c1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C16H16F2N2O/c17-13-4-1-5-14(18)15(13)21-16-12(3-2-8-20-16)11-6-9-19-10-7-11/h1-5,8,11,19H,6-7,9-10H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	181	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50309519 (2-(2-chloro-6-fluorophenoxy)-3-(piperidin-4-yl)pyr...) Show SMILES Fc1cccc(Cl)c1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C16H16ClFN2O/c17-13-4-1-5-14(18)15(13)21-16-12(3-2-8-20-16)11-6-9-19-10-7-11/h1-5,8,11,19H,6-7,9-10H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	194	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50309511 (3-(piperidin-4-yl)-2-(2-(trifluoromethyl)phenoxy)p...) Show SMILES FC(F)(F)c1ccccc1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C17H17F3N2O/c18-17(19,20)14-5-1-2-6-15(14)23-16-13(4-3-9-22-16)12-7-10-21-11-8-12/h1-6,9,12,21H,7-8,10-11H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	203	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50309517 (2-(2-chloro-5-fluorophenoxy)-3-(piperidin-4-yl)pyr...) Show SMILES Fc1ccc(Cl)c(Oc2ncccc2C2CCNCC2)c1 Show InChI InChI=1S/C16H16ClFN2O/c17-14-4-3-12(18)10-15(14)21-16-13(2-1-7-20-16)11-5-8-19-9-6-11/h1-4,7,10-11,19H,5-6,8-9H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	247	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50309517 (2-(2-chloro-5-fluorophenoxy)-3-(piperidin-4-yl)pyr...) Show SMILES Fc1ccc(Cl)c(Oc2ncccc2C2CCNCC2)c1 Show InChI InChI=1S/C16H16ClFN2O/c17-14-4-3-12(18)10-15(14)21-16-13(2-1-7-20-16)11-5-8-19-9-6-11/h1-4,7,10-11,19H,5-6,8-9H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	251	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50309518 (2-(2-fluoro-6-methoxyphenoxy)-3-(piperidin-4-yl)py...) Show SMILES COc1cccc(F)c1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C17H19FN2O2/c1-21-15-6-2-5-14(18)16(15)22-17-13(4-3-9-20-17)12-7-10-19-11-8-12/h2-6,9,12,19H,7-8,10-11H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	276	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50309505 (4-(2-fluoro-6-(2-fluorophenoxy)phenyl)piperidine |...) Show SMILES Fc1ccccc1Oc1cccc(F)c1C1CCNCC1 Show InChI InChI=1S/C17H17F2NO/c18-13-4-1-2-6-15(13)21-16-7-3-5-14(19)17(16)12-8-10-20-11-9-12/h1-7,12,20H,8-11H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	278	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]WIN35428 from human DAT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50309510 (3-(piperidin-4-yl)-2-(o-tolyloxy)pyridine | CHEMBL...) Show SMILES Cc1ccccc1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C17H20N2O/c1-13-5-2-3-7-16(13)20-17-15(6-4-10-19-17)14-8-11-18-12-9-14/h2-7,10,14,18H,8-9,11-12H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	292	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50309509 (2-(2-methoxyphenoxy)-3-(piperidin-4-yl)pyridine | ...) Show SMILES COc1ccccc1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C17H20N2O2/c1-20-15-6-2-3-7-16(15)21-17-14(5-4-10-19-17)13-8-11-18-12-9-13/h2-7,10,13,18H,8-9,11-12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	292	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent dopamine transporter (Homo sapiens (Human))	BDBM50309512 (2-(2,3-dichlorophenoxy)-3-(piperidin-4-yl)pyridine...) Show SMILES Clc1cccc(Oc2ncccc2C2CCNCC2)c1Cl Show InChI InChI=1S/C16H16Cl2N2O/c17-13-4-1-5-14(15(13)18)21-16-12(3-2-8-20-16)11-6-9-19-10-7-11/h1-5,8,11,19H,6-7,9-10H2	NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	310	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]WIN35428 from human DAT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50309510 (3-(piperidin-4-yl)-2-(o-tolyloxy)pyridine | CHEMBL...) Show SMILES Cc1ccccc1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C17H20N2O/c1-13-5-2-3-7-16(13)20-17-15(6-4-10-19-17)14-8-11-18-12-9-14/h2-7,10,14,18H,8-9,11-12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	330	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50309515 (2-(2,4-dichlorophenoxy)-3-(piperidin-4-yl)pyridine...) Show SMILES Clc1ccc(Oc2ncccc2C2CCNCC2)c(Cl)c1 Show InChI InChI=1S/C16H16Cl2N2O/c17-12-3-4-15(14(18)10-12)21-16-13(2-1-7-20-16)11-5-8-19-9-6-11/h1-4,7,10-11,19H,5-6,8-9H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	413	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50309507 (2-(2-fluorophenoxy)-3-(piperidin-4-yl)pyridine | C...) Show SMILES Fc1ccccc1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C16H17FN2O/c17-14-5-1-2-6-15(14)20-16-13(4-3-9-19-16)12-7-10-18-11-8-12/h1-6,9,12,18H,7-8,10-11H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	536	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50309509 (2-(2-methoxyphenoxy)-3-(piperidin-4-yl)pyridine | ...) Show SMILES COc1ccccc1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C17H20N2O2/c1-20-15-6-2-3-7-16(15)21-17-14(5-4-10-19-17)13-8-11-18-12-9-13/h2-7,10,13,18H,8-9,11-12H2,1H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	610	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50309523 (1-(2-(2-chloro-6-fluorophenoxy)pyridin-3-yl)pipera...) Show SMILES Fc1cccc(Cl)c1Oc1ncccc1N1CCNCC1 Show InChI InChI=1S/C15H15ClFN3O/c16-11-3-1-4-12(17)14(11)21-15-13(5-2-6-19-15)20-9-7-18-8-10-20/h1-6,18H,7-10H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	663	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50309507 (2-(2-fluorophenoxy)-3-(piperidin-4-yl)pyridine | C...) Show SMILES Fc1ccccc1Oc1ncccc1C1CCNCC1 Show InChI InChI=1S/C16H17FN2O/c17-14-5-1-2-6-15(14)20-16-13(4-3-9-19-16)12-7-10-18-11-8-12/h1-6,9,12,18H,7-8,10-11H2	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	728	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]citalopram from human SERT expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50309522 (1-(2-(2-chlorophenoxy)pyridin-3-yl)piperazine | CH...) Show SMILES Clc1ccccc1Oc1ncccc1N1CCNCC1 Show InChI InChI=1S/C15H16ClN3O/c16-12-4-1-2-6-14(12)20-15-13(5-3-7-18-15)19-10-8-17-9-11-19/h1-7,17H,8-11H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	747	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]nisoxetine from human NET expressed in HEK293 cells by scintillation proximity assay				Bioorg Med Chem Lett 20: 1114-7 (2010) Article DOI: 10.1016/j.bmcl.2009.12.023 BindingDB Entry DOI: 10.7270/Q2NS0V17
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 84 total )  |  Next  |  Last  >>

Jump to: