Compile Data Set for Download or QSAR

Found 92 hits Enz. Inhib. hit(s) with all data for entry = 50031251   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309873 (4-(6-Chlorooxazolo[4,5-b]pyridin-2-yl)-1,4-diazabi...) Show SMILES Clc1cnc2nc(oc2c1)N1CCN2CCC1CC2 |TLB:6:10:15.14:17.18,(-1.41,-19.11,;-1.97,-20.56,;-.99,-21.77,;-1.55,-23.21,;-3.08,-23.45,;-3.94,-24.73,;-5.43,-24.32,;-5.49,-22.78,;-4.05,-22.24,;-3.49,-20.8,;-6.76,-25.09,;-6.39,-26.56,;-7.4,-25.84,;-8.78,-25.91,;-8.85,-24.2,;-8.23,-23.06,;-8.17,-24.47,;-9.47,-25.17,;-9.77,-26.61,)| Show InChI InChI=1S/C13H15ClN4O/c14-9-7-11-12(15-8-9)16-13(19-11)18-6-5-17-3-1-10(18)2-4-17/h7-8,10H,1-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Mus musculus (house mouse))	BDBM50309864 (4-(5-Chlorobenzoxazol-2-yl)-1,4-diazabicyclo[3.2.2...) Show SMILES Clc1ccc2oc(nc2c1)N1CCN2CCC1CC2 |TLB:6:10:15.14:17.18,(33.87,4.67,;32.34,4.44,;31.36,5.65,;29.84,5.41,;29.28,3.97,;27.84,3.42,;27.9,1.89,;29.4,1.48,;30.25,2.76,;31.78,2.99,;26.57,1.11,;26.94,-.35,;25.94,.37,;24.56,.3,;24.48,2.01,;25.1,3.15,;25.16,1.74,;23.87,1.03,;23.57,-.41,)| Show InChI InChI=1S/C14H16ClN3O/c15-10-1-2-13-12(9-10)16-14(19-13)18-8-7-17-5-3-11(18)4-6-17/h1-2,9,11H,3-8H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309897 (2-(1,4-Diazabicyclo[3.2.2]nonan-4-yl)-5-(pyrrolidi...) Show SMILES C1CCN(C1)c1ccc2oc(nc2n1)N1CCN2CCC1CC2 |TLB:10:14:19.18:21.22,(20.91,-33.41,;20.89,-31.87,;19.42,-31.41,;18.52,-32.67,;19.45,-33.91,;16.98,-32.69,;16,-31.49,;14.48,-31.72,;13.92,-33.16,;12.48,-33.7,;12.54,-35.24,;14.04,-35.65,;14.89,-34.37,;16.41,-34.13,;11.22,-36.01,;11.58,-37.48,;10.58,-36.75,;9.2,-36.82,;9.13,-35.12,;9.75,-33.98,;9.81,-35.39,;8.51,-36.09,;8.21,-37.53,)| Show InChI InChI=1S/C17H23N5O/c1-2-8-21(7-1)15-4-3-14-16(18-15)19-17(23-14)22-12-11-20-9-5-13(22)6-10-20/h3-4,13H,1-2,5-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309864 (4-(5-Chlorobenzoxazol-2-yl)-1,4-diazabicyclo[3.2.2...) Show SMILES Clc1ccc2oc(nc2c1)N1CCN2CCC1CC2 |TLB:6:10:15.14:17.18,(33.87,4.67,;32.34,4.44,;31.36,5.65,;29.84,5.41,;29.28,3.97,;27.84,3.42,;27.9,1.89,;29.4,1.48,;30.25,2.76,;31.78,2.99,;26.57,1.11,;26.94,-.35,;25.94,.37,;24.56,.3,;24.48,2.01,;25.1,3.15,;25.16,1.74,;23.87,1.03,;23.57,-.41,)| Show InChI InChI=1S/C14H16ClN3O/c15-10-1-2-13-12(9-10)16-14(19-13)18-8-7-17-5-3-11(18)4-6-17/h1-2,9,11H,3-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309872 (4-(6-Bromooxazolo[4,5-b]pyridin-2-yl)-1,4-diazabic...) Show SMILES Brc1cnc2nc(oc2c1)N1CCN2CCC1CC2 |TLB:6:10:15.14:17.18,(31.84,-7.59,;31.28,-9.04,;32.26,-10.25,;31.7,-11.69,;30.17,-11.93,;29.32,-13.21,;27.82,-12.8,;27.76,-11.26,;29.2,-10.72,;29.76,-9.28,;26.49,-13.57,;26.86,-15.04,;25.85,-14.32,;24.48,-14.39,;24.4,-12.68,;25.02,-11.54,;25.08,-12.95,;23.79,-13.65,;23.49,-15.09,)| Show InChI InChI=1S/C13H15BrN4O/c14-9-7-11-12(15-8-9)16-13(19-11)18-6-5-17-3-1-10(18)2-4-17/h7-8,10H,1-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.08	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309865 (4-(5-Bromobenzoxazol-2-yl)-1,4-diazabicyclo[3.2.2]...) Show SMILES Brc1ccc2oc(nc2c1)N1CCN2CCC1CC2 |TLB:6:10:15.14:17.18,(.18,-3.78,;-1.35,-4.01,;-2.33,-2.8,;-3.85,-3.04,;-4.41,-4.48,;-5.85,-5.03,;-5.79,-6.56,;-4.3,-6.97,;-3.44,-5.69,;-1.92,-5.46,;-7.12,-7.33,;-6.75,-8.8,;-7.76,-8.08,;-9.13,-8.15,;-9.21,-6.44,;-8.59,-5.3,;-8.53,-6.71,;-9.82,-7.41,;-10.12,-8.86,)| Show InChI InChI=1S/C14H16BrN3O/c15-10-1-2-13-12(9-10)16-14(19-13)18-8-7-17-5-3-11(18)4-6-17/h1-2,9,11H,3-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.15	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309880 (4-(6-Phenyloxazolo[5,4-b]pyridin-2-yl)-1,4-diazabi...) Show SMILES C1CN2CCC1N(CC2)c1nc2cc(cnc2o1)-c1ccccc1 |TLB:9:6:0.1:4.3,(-10.27,-43.52,;-10.9,-44.66,;-10.81,-46.36,;-11.81,-47.07,;-11.51,-45.63,;-10.21,-44.93,;-8.8,-45.55,;-8.44,-47.01,;-9.44,-46.29,;-7.48,-44.78,;-5.99,-45.19,;-5.14,-43.91,;-3.61,-43.68,;-3.05,-42.24,;-4.03,-41.03,;-5.55,-41.27,;-6.1,-42.7,;-7.54,-43.25,;-1.71,-41.48,;-.39,-42.27,;.96,-41.51,;.97,-39.96,;-.37,-39.18,;-1.71,-39.94,)| Show InChI InChI=1S/C19H20N4O/c1-2-4-14(5-3-1)15-12-17-18(20-13-15)24-19(21-17)23-11-10-22-8-6-16(23)7-9-22/h1-5,12-13,16H,6-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	2.31	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309879 (2-(6-Chlorooxazolo[5,4-b]pyridin-2-yl)-2,5-diazabi...) Show SMILES Clc1cnc2oc(nc2c1)N1CCN2CCC1CC2 |TLB:6:10:15.14:17.18,(32.86,-26.98,;31.33,-27.22,;30.35,-26.01,;28.83,-26.25,;28.27,-27.69,;26.83,-28.23,;26.89,-29.77,;28.39,-30.18,;29.24,-28.9,;30.77,-28.66,;25.56,-30.54,;25.93,-32.01,;24.92,-31.29,;23.55,-31.36,;23.47,-29.65,;24.09,-28.51,;24.15,-29.92,;22.85,-30.62,;22.55,-32.06,)| Show InChI InChI=1S/C13H15ClN4O/c14-9-7-11-12(15-8-9)19-13(16-11)18-6-5-17-3-1-10(18)2-4-17/h7-8,10H,1-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309888 (4-(6-Chloro-5-methyloxazolo[4,5-b]pyridin-2-yl)-1,...) Show SMILES Cc1nc2nc(oc2cc1Cl)N1CCN2CCC1CC2 |TLB:5:11:16.15:18.19,(1.04,-10.22,;-.49,-10.46,;-1.05,-11.9,;-2.58,-12.13,;-3.43,-13.41,;-4.92,-13,;-4.98,-11.47,;-3.54,-10.92,;-2.99,-9.49,;-1.46,-9.25,;-.9,-7.79,;-6.25,-13.78,;-5.89,-15.24,;-6.89,-14.52,;-8.27,-14.59,;-8.34,-12.89,;-7.73,-11.74,;-7.66,-13.15,;-8.96,-13.86,;-9.26,-15.3,)| Show InChI InChI=1S/C14H17ClN4O/c1-9-11(15)8-12-13(16-9)17-14(20-12)19-7-6-18-4-2-10(19)3-5-18/h8,10H,2-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.19	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309892 (2-(5-Phenyloxazolo[4,5-b]pyridin-2-yl)-2,5-diazabi...) Show SMILES C1CN2CCC1N(CC2)c1nc2nc(ccc2o1)-c1ccccc1 |TLB:9:6:0.1:4.3,(-8.33,-22.75,;-8.95,-23.89,;-8.87,-25.59,;-9.86,-26.3,;-9.56,-24.86,;-8.27,-24.16,;-6.86,-24.78,;-6.49,-26.25,;-7.5,-25.53,;-5.53,-24.01,;-4.04,-24.42,;-3.19,-23.14,;-1.66,-22.9,;-1.1,-21.46,;-2.07,-20.26,;-3.6,-20.5,;-4.15,-21.93,;-5.59,-22.48,;.25,-20.71,;1.57,-21.5,;2.92,-20.74,;2.94,-19.2,;1.6,-18.41,;.26,-19.17,)| Show InChI InChI=1S/C19H20N4O/c1-2-4-14(5-3-1)16-6-7-17-18(20-16)21-19(24-17)23-13-12-22-10-8-15(23)9-11-22/h1-7,15H,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.22	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Mus musculus (house mouse))	BDBM50309866 (4-(5-Methylbenzoxazol-2-yl)-1,4-diazabicyclo[3.2.2...) Show SMILES Cc1ccc2oc(nc2c1)N1CCN2CCC1CC2 |TLB:6:10:15.14:17.18,(11.7,-3.08,;10.17,-3.31,;9.19,-2.1,;7.67,-2.34,;7.11,-3.78,;5.67,-4.33,;5.73,-5.86,;7.23,-6.27,;8.08,-4.99,;9.61,-4.76,;4.4,-6.63,;4.77,-8.1,;3.76,-7.38,;2.39,-7.45,;2.31,-5.74,;2.93,-4.6,;2.99,-6.01,;1.7,-6.71,;1.4,-8.15,)| Show InChI InChI=1S/C15H19N3O/c1-11-2-3-14-13(10-11)16-15(19-14)18-9-8-17-6-4-12(18)5-7-17/h2-3,10,12H,4-9H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309893 (2-(5-(2-Fluorophenyl)oxazolo[4,5-b]pyridin-2-yl)-2...) Show SMILES Fc1ccccc1-c1ccc2oc(nc2n1)N1CCN2CCC1CC2 |TLB:12:16:21.20:23.24,(13.59,-22.93,;13.62,-21.39,;14.96,-20.63,;14.98,-19.08,;13.64,-18.29,;12.3,-19.05,;12.29,-20.59,;10.94,-21.35,;9.97,-20.14,;8.45,-20.38,;7.89,-21.81,;6.45,-22.36,;6.51,-23.89,;8,-24.3,;8.86,-23.02,;10.38,-22.79,;5.18,-24.67,;5.55,-26.13,;4.55,-25.41,;3.17,-25.48,;3.1,-23.78,;3.71,-22.63,;3.77,-24.05,;2.48,-24.75,;2.18,-26.19,)| Show InChI InChI=1S/C19H19FN4O/c20-15-4-2-1-3-14(15)16-5-6-17-18(21-16)22-19(25-17)24-12-11-23-9-7-13(24)8-10-23/h1-6,13H,7-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Mus musculus (house mouse))	BDBM50309863 (4-(5-Fluorobenzoxazol-2-yl)-1,4-diazabicyclo[3.2.2...) Show SMILES Fc1ccc2oc(nc2c1)N1CCN2CCC1CC2 |TLB:6:10:15.14:17.18,(22.74,5.07,;21.21,4.83,;20.23,6.04,;18.71,5.8,;18.15,4.37,;16.71,3.82,;16.77,2.29,;18.27,1.88,;19.12,3.16,;20.65,3.39,;15.44,1.51,;15.81,.04,;14.8,.77,;13.43,.7,;13.35,2.4,;13.97,3.55,;14.03,2.13,;12.74,1.43,;12.44,-.01,)| Show InChI InChI=1S/C14H16FN3O/c15-10-1-2-13-12(9-10)16-14(19-13)18-8-7-17-5-3-11(18)4-6-17/h1-2,9,11H,3-8H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309886 (2-(6-Phenoxyoxazolo[4,5-b]pyridin-2-yl)-2,5-diazab...) Show SMILES C1CN2CCC1N(CC2)c1nc2ncc(Oc3ccccc3)cc2o1 |TLB:9:6:0.1:4.3,(12.67,-1.62,;12.06,-2.77,;12.13,-4.47,;11.15,-5.17,;11.44,-3.73,;12.74,-3.03,;14.14,-3.65,;14.51,-5.12,;13.51,-4.4,;15.47,-2.88,;16.96,-3.29,;17.81,-2.01,;19.34,-1.78,;19.9,-.34,;18.92,.87,;19.48,2.32,;20.83,3.08,;22.17,2.29,;23.52,3.05,;23.53,4.6,;22.18,5.39,;20.84,4.62,;17.4,.63,;16.85,-.81,;15.41,-1.35,)| Show InChI InChI=1S/C19H20N4O2/c1-2-4-15(5-3-1)24-16-12-17-18(20-13-16)21-19(25-17)23-11-10-22-8-6-14(23)7-9-22/h1-5,12-14H,6-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.16	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309891 (2-(5-Cyclopentyloxazolo[4,5-b]pyridin-2-yl)-2,5-di...) Show SMILES C1CCC(C1)c1ccc2oc(nc2n1)N1CCN2CCC1CC2 |TLB:10:14:19.18:21.22,(36.18,-10.06,;35.94,-8.53,;34.41,-8.28,;33.71,-9.66,;34.8,-10.75,;32.18,-9.9,;31.21,-8.69,;29.69,-8.93,;29.13,-10.36,;27.69,-10.91,;27.75,-12.44,;29.24,-12.85,;30.1,-11.57,;31.62,-11.34,;26.42,-13.21,;26.79,-14.68,;25.79,-13.96,;24.41,-14.03,;24.34,-12.33,;24.95,-11.18,;25.02,-12.59,;23.72,-13.3,;23.42,-14.73,)| Show InChI InChI=1S/C18H24N4O/c1-2-4-13(3-1)15-5-6-16-17(19-15)20-18(23-16)22-12-11-21-9-7-14(22)8-10-21/h5-6,13-14H,1-4,7-12H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309882 (4-(6-Cyanooxazolo[4,5-b]pyridin-2-yl)-1,4-diazabic...) Show SMILES N#Cc1cnc2nc(oc2c1)N1CCN2CCC1CC2 |TLB:7:11:16.15:18.19,(18.05,-37.42,;17.5,-38.87,;16.94,-40.32,;17.92,-41.53,;17.36,-42.97,;15.83,-43.2,;14.98,-44.48,;13.48,-44.07,;13.42,-42.54,;14.86,-41.99,;15.42,-40.56,;12.15,-44.85,;12.52,-46.31,;11.51,-45.59,;10.14,-45.66,;10.06,-43.96,;10.68,-42.81,;10.74,-44.22,;9.45,-44.93,;9.15,-46.37,)| Show InChI InChI=1S/C14H15N5O/c15-8-10-7-12-13(16-9-10)17-14(20-12)19-6-5-18-3-1-11(19)2-4-18/h7,9,11H,1-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309875 (4-(6-Methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabi...) Show SMILES Cc1cnc2nc(oc2c1)N1CCN2CCC1CC2 |TLB:6:10:15.14:17.18,(18.8,-18.14,;18.24,-19.59,;19.22,-20.8,;18.66,-22.24,;17.13,-22.47,;16.28,-23.76,;14.78,-23.34,;14.72,-21.81,;16.16,-21.26,;16.72,-19.83,;13.45,-24.12,;13.82,-25.59,;12.81,-24.86,;11.44,-24.93,;11.36,-23.23,;11.98,-22.08,;12.04,-23.5,;10.75,-24.2,;10.45,-25.64,)| Show InChI InChI=1S/C14H18N4O/c1-10-8-12-13(15-9-10)16-14(19-12)18-7-6-17-4-2-11(18)3-5-17/h8-9,11H,2-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.66	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309878 (4-(6-Phenyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabi...) Show SMILES C1CN2CCC1N(CC2)c1nc2ncc(cc2o1)-c1ccccc1 |TLB:9:6:0.1:4.3,(.58,-33.05,;-.04,-34.19,;.04,-35.89,;-.95,-36.59,;-.65,-35.16,;.64,-34.46,;2.04,-35.08,;2.41,-36.54,;1.4,-35.82,;3.36,-34.31,;4.85,-34.72,;5.7,-33.44,;7.22,-33.21,;7.78,-31.77,;6.8,-30.57,;5.29,-30.81,;4.74,-32.24,;3.3,-32.78,;7.56,-29.22,;9.11,-29.2,;9.86,-27.86,;9.07,-26.53,;7.52,-26.55,;6.77,-27.9,)| Show InChI InChI=1S/C19H20N4O/c1-2-4-14(5-3-1)15-12-17-18(20-13-15)21-19(24-17)23-11-10-22-8-6-16(23)7-9-22/h1-5,12-13,16H,6-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.04	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309890 (2-(5-Isopropyloxazolo[4,5-b]pyridin-2-yl)-2,5-diaz...) Show SMILES CC(C)c1ccc2oc(nc2n1)N1CCN2CCC1CC2 |TLB:8:12:17.16:19.20,(22.84,-11.83,;22.02,-10.51,;22.76,-9.15,;20.48,-10.55,;19.5,-9.35,;17.98,-9.59,;17.42,-11.02,;15.98,-11.57,;16.04,-13.1,;17.53,-13.51,;18.39,-12.23,;19.91,-12,;14.71,-13.87,;15.08,-15.34,;14.07,-14.62,;12.7,-14.69,;12.62,-12.98,;13.24,-11.84,;13.3,-13.25,;12.01,-13.96,;11.71,-15.4,)| Show InChI InChI=1S/C16H22N4O/c1-11(2)13-3-4-14-15(17-13)18-16(21-14)20-10-9-19-7-5-12(20)6-8-19/h3-4,11-12H,5-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.05	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Mus musculus (house mouse))	BDBM50309862 (4-Benzoxazo-2-yl-1,4-diazabicyclo[3.2.2]nonane | C...) Show SMILES C1CN2CCC1N(CC2)c1nc2ccccc2o1 |TLB:9:6:0.1:4.3,(3.81,3.82,;3.19,2.68,;3.27,.97,;2.28,.27,;2.58,1.71,;3.87,2.41,;5.28,1.79,;5.65,.32,;4.64,1.04,;6.61,2.56,;8.11,2.15,;8.96,3.43,;10.49,3.66,;11.05,5.11,;10.07,6.32,;8.55,6.08,;7.99,4.64,;6.55,4.09,)| Show InChI InChI=1S/C14H17N3O/c1-2-4-13-12(3-1)15-14(18-13)17-10-9-16-7-5-11(17)6-8-16/h1-4,11H,5-10H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309861 (4-(5-Methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabi...) Show SMILES Cc1ccc2oc(nc2n1)N1CCN2CCC1CC2 |TLB:6:10:15.14:17.18,(20.91,-29.51,;19.38,-29.74,;18.4,-28.53,;16.88,-28.77,;16.32,-30.21,;14.88,-30.76,;14.94,-32.29,;16.44,-32.7,;17.29,-31.42,;18.82,-31.19,;13.61,-33.07,;13.98,-34.53,;12.97,-33.81,;11.6,-33.88,;11.52,-32.18,;12.14,-31.03,;12.2,-32.44,;10.91,-33.15,;10.61,-34.59,)| Show InChI InChI=1S/C14H18N4O/c1-10-2-3-12-13(15-10)16-14(19-12)18-9-8-17-6-4-11(18)5-7-17/h2-3,11H,4-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	13.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309887 (4-(6-Fluoro-5-methyloxazolo[4,5-b]pyridin-2-yl)-1,...) Show SMILES Cc1nc2nc(oc2cc1F)N1CCN2CCC1CC2 |TLB:5:11:16.15:18.19,(31.85,-.7,;30.32,-.94,;29.76,-2.38,;28.23,-2.62,;27.38,-3.9,;25.89,-3.49,;25.83,-1.95,;27.27,-1.41,;27.82,.03,;29.35,.27,;29.91,1.72,;24.56,-4.26,;24.92,-5.73,;23.92,-5.01,;22.54,-5.08,;22.47,-3.37,;23.08,-2.23,;23.15,-3.64,;21.85,-4.34,;21.55,-5.78,)| Show InChI InChI=1S/C14H17FN4O/c1-9-11(15)8-12-13(16-9)17-14(20-12)19-7-6-18-4-2-10(19)3-5-18/h8,10H,2-7H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Homo sapiens (Human))	BDBM50309861 (4-(5-Methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabi...) Show SMILES Cc1ccc2oc(nc2n1)N1CCN2CCC1CC2 |TLB:6:10:15.14:17.18,(20.91,-29.51,;19.38,-29.74,;18.4,-28.53,;16.88,-28.77,;16.32,-30.21,;14.88,-30.76,;14.94,-32.29,;16.44,-32.7,;17.29,-31.42,;18.82,-31.19,;13.61,-33.07,;13.98,-34.53,;12.97,-33.81,;11.6,-33.88,;11.52,-32.18,;12.14,-31.03,;12.2,-32.44,;10.91,-33.15,;10.61,-34.59,)| Show InChI InChI=1S/C14H18N4O/c1-10-2-3-12-13(15-10)16-14(19-12)18-9-8-17-6-4-11(18)5-7-17/h2-3,11H,4-9H2,1H3	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	16.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from human alpha7 nicotinic acetylcholine receptor expressed in IMR32 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309874 (4-(6-Fluorooxazolo[4,5-b]pyridin-2-yl)-1,4-diazabi...) Show SMILES Fc1cnc2nc(oc2c1)N1CCN2CCC1CC2 |TLB:6:10:15.14:17.18,(8.59,-18.46,;8.03,-19.91,;9,-21.12,;8.44,-22.56,;6.91,-22.8,;6.06,-24.08,;4.57,-23.67,;4.5,-22.13,;5.95,-21.59,;6.5,-20.15,;3.23,-24.44,;3.6,-25.91,;2.6,-25.19,;1.22,-25.26,;1.14,-23.55,;1.76,-22.41,;1.82,-23.82,;.53,-24.52,;.23,-25.96,)| Show InChI InChI=1S/C13H15FN4O/c14-9-7-11-12(15-8-9)16-13(19-11)18-6-5-17-3-1-10(18)2-4-17/h7-8,10H,1-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309895 (2-(5-Phenoxyoxazolo[4,5-b]pyridin-2-yl)-2,5-diazab...) Show SMILES C1CN2CCC1N(CC2)c1nc2nc(Oc3ccccc3)ccc2o1 |TLB:9:6:0.1:4.3,(28.2,-22.15,;27.59,-23.29,;27.66,-25,;26.67,-25.7,;26.97,-24.26,;28.26,-23.56,;29.67,-24.18,;30.04,-25.65,;29.04,-24.93,;31,-23.41,;32.49,-23.82,;33.35,-22.54,;34.87,-22.31,;35.43,-20.87,;36.78,-20.11,;38.11,-20.89,;38.09,-22.44,;39.42,-23.23,;40.77,-22.47,;40.78,-20.92,;39.45,-20.13,;34.46,-19.66,;32.94,-19.9,;32.38,-21.33,;30.94,-21.88,)| Show InChI InChI=1S/C19H20N4O2/c1-2-4-15(5-3-1)24-17-7-6-16-18(20-17)21-19(25-16)23-13-12-22-10-8-14(23)9-11-22/h1-7,14H,8-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309867 (4-(6-Methylbenzoxazol-2-yl)-1,4-diazabicyclo[3.2.2...) Show SMILES Cc1ccc2nc(oc2c1)N1CCN2CCC1CC2 |TLB:6:10:15.14:17.18,(21.08,.1,;20.52,-1.35,;21.5,-2.56,;20.93,-4,;19.41,-4.23,;18.55,-5.51,;17.06,-5.1,;17,-3.57,;18.44,-3.02,;19,-1.59,;15.73,-5.88,;16.1,-7.34,;15.09,-6.62,;13.72,-6.69,;13.64,-4.99,;14.26,-3.84,;14.32,-5.25,;13.03,-5.96,;12.73,-7.4,)| Show InChI InChI=1S/C15H19N3O/c1-11-2-3-13-14(10-11)19-15(16-13)18-9-8-17-6-4-12(18)5-7-17/h2-3,10,12H,4-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	17.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309889 (2-(5-Ethyloxazolo[4,5-b]pyridin-2-yl)-2,5-diazabic...) Show SMILES CCc1ccc2oc(nc2n1)N1CCN2CCC1CC2 |TLB:7:11:16.15:18.19,(12.49,-11.15,;11.52,-9.95,;9.99,-10.18,;9.01,-8.97,;7.49,-9.21,;6.93,-10.65,;5.49,-11.2,;5.55,-12.73,;7.05,-13.14,;7.9,-11.86,;9.43,-11.63,;4.22,-13.5,;4.59,-14.97,;3.58,-14.25,;2.21,-14.32,;2.13,-12.61,;2.75,-11.47,;2.81,-12.88,;1.52,-13.58,;1.22,-15.03,)| Show InChI InChI=1S/C15H20N4O/c1-2-11-3-4-13-14(16-11)17-15(20-13)19-10-9-18-7-5-12(19)6-8-18/h3-4,12H,2,5-10H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	18.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309863 (4-(5-Fluorobenzoxazol-2-yl)-1,4-diazabicyclo[3.2.2...) Show SMILES Fc1ccc2oc(nc2c1)N1CCN2CCC1CC2 |TLB:6:10:15.14:17.18,(22.74,5.07,;21.21,4.83,;20.23,6.04,;18.71,5.8,;18.15,4.37,;16.71,3.82,;16.77,2.29,;18.27,1.88,;19.12,3.16,;20.65,3.39,;15.44,1.51,;15.81,.04,;14.8,.77,;13.43,.7,;13.35,2.4,;13.97,3.55,;14.03,2.13,;12.74,1.43,;12.44,-.01,)| Show InChI InChI=1S/C14H16FN3O/c15-10-1-2-13-12(9-10)16-14(19-13)18-8-7-17-5-3-11(18)4-6-17/h1-2,9,11H,3-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	20.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309876 (4-(6-Ethyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabic...) Show SMILES CCc1cnc2nc(oc2c1)N1CCN2CCC1CC2 |TLB:7:11:16.15:18.19,(30.33,-18.3,;28.77,-18.33,;28.02,-19.69,;28.99,-20.9,;28.43,-22.34,;26.9,-22.57,;26.05,-23.85,;24.56,-23.44,;24.5,-21.91,;25.94,-21.36,;26.49,-19.93,;23.23,-24.22,;23.59,-25.68,;22.59,-24.96,;21.21,-25.03,;21.14,-23.33,;21.76,-22.18,;21.82,-23.6,;20.52,-24.3,;20.22,-25.74,)| Show InChI InChI=1S/C15H20N4O/c1-2-11-9-13-14(16-10-11)17-15(20-13)19-8-7-18-5-3-12(19)4-6-18/h9-10,12H,2-8H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309862 (4-Benzoxazo-2-yl-1,4-diazabicyclo[3.2.2]nonane | C...) Show SMILES C1CN2CCC1N(CC2)c1nc2ccccc2o1 |TLB:9:6:0.1:4.3,(3.81,3.82,;3.19,2.68,;3.27,.97,;2.28,.27,;2.58,1.71,;3.87,2.41,;5.28,1.79,;5.65,.32,;4.64,1.04,;6.61,2.56,;8.11,2.15,;8.96,3.43,;10.49,3.66,;11.05,5.11,;10.07,6.32,;8.55,6.08,;7.99,4.64,;6.55,4.09,)| Show InChI InChI=1S/C14H17N3O/c1-2-4-13-12(3-1)15-14(18-13)17-10-9-16-7-5-11(17)6-8-16/h1-4,11H,5-10H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	22.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309883 (2-(6-(1H-Pyrazol-3-yl)oxazolo[4,5-b]pyridin-2-yl)-...) Show SMILES C1CN2CCC1N(CC2)c1nc2ncc(cc2o1)-c1cc[nH]n1 |TLB:9:6:0.1:4.3,(22.19,-41.04,;21.57,-42.18,;21.65,-43.89,;20.66,-44.59,;20.96,-43.15,;22.25,-42.45,;23.66,-43.07,;24.03,-44.54,;23.02,-43.82,;24.99,-42.3,;26.48,-42.71,;27.33,-41.43,;28.86,-41.2,;29.42,-39.76,;28.45,-38.55,;26.92,-38.79,;26.37,-40.22,;24.93,-40.77,;28.93,-37.07,;30.39,-36.6,;30.41,-35.04,;28.93,-34.55,;28.01,-35.81,)| Show InChI InChI=1S/C16H18N6O/c1-4-18-20-13(1)11-9-14-15(17-10-11)19-16(23-14)22-8-7-21-5-2-12(22)3-6-21/h1,4,9-10,12H,2-3,5-8H2,(H,18,20)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	23	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309894 (2-(5-Methoxyoxazolo[4,5-b]pyridin-2-yl)-2,5-diazab...) Show SMILES COc1ccc2oc(nc2n1)N1CCN2CCC1CC2 |TLB:7:11:16.15:18.19,(28.27,-20.16,;26.94,-19.37,;25.59,-20.13,;24.61,-18.93,;23.09,-19.17,;22.53,-20.6,;21.09,-21.15,;21.15,-22.68,;22.64,-23.09,;23.5,-21.81,;25.02,-21.58,;19.82,-23.46,;20.19,-24.92,;19.18,-24.2,;17.8,-24.27,;17.73,-22.57,;18.35,-21.42,;18.41,-22.83,;17.11,-23.54,;16.81,-24.98,)| Show InChI InChI=1S/C14H18N4O2/c1-19-12-3-2-11-13(15-12)16-14(20-11)18-9-8-17-6-4-10(18)5-7-17/h2-3,10H,4-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	24.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309868 (4-Oxazolo[4,5-b]pyridin-2-yl-1,4-diazabicyclo[3.2....) Show SMILES C1CN2CCC1N(CC2)c1nc2ncccc2o1 |TLB:9:6:0.1:4.3,(27.22,-2.94,;26.61,-4.09,;26.68,-5.8,;25.69,-6.51,;25.99,-5.06,;27.29,-4.36,;28.7,-4.98,;29.07,-6.45,;28.06,-5.73,;30.03,-4.21,;31.53,-4.62,;32.38,-3.34,;33.91,-3.1,;34.48,-1.66,;33.5,-.45,;31.97,-.69,;31.42,-2.12,;29.97,-2.67,)| Show InChI InChI=1S/C13H16N4O/c1-2-11-12(14-5-1)15-13(18-11)17-9-8-16-6-3-10(17)4-7-16/h1-2,5,10H,3-4,6-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309866 (4-(5-Methylbenzoxazol-2-yl)-1,4-diazabicyclo[3.2.2...) Show SMILES Cc1ccc2oc(nc2c1)N1CCN2CCC1CC2 |TLB:6:10:15.14:17.18,(11.7,-3.08,;10.17,-3.31,;9.19,-2.1,;7.67,-2.34,;7.11,-3.78,;5.67,-4.33,;5.73,-5.86,;7.23,-6.27,;8.08,-4.99,;9.61,-4.76,;4.4,-6.63,;4.77,-8.1,;3.76,-7.38,;2.39,-7.45,;2.31,-5.74,;2.93,-4.6,;2.99,-6.01,;1.7,-6.71,;1.4,-8.15,)| Show InChI InChI=1S/C15H19N3O/c1-11-2-3-14-13(10-11)16-15(19-14)18-9-8-17-6-4-12(18)5-7-17/h2-3,10,12H,4-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309871 (4-Oxazolo[5,4-b]pyridin-2-yl-1,4-diazabicyclo[3.2....) Show SMILES C1CN2CCC1N(CC2)c1nc2cccnc2o1 |TLB:9:6:0.1:4.3,(13.79,-11.99,;13.17,-13.13,;13.25,-14.84,;12.26,-15.55,;12.56,-14.11,;13.86,-13.4,;15.27,-14.03,;15.64,-15.5,;14.63,-14.77,;16.6,-13.25,;18.1,-13.66,;18.95,-12.38,;20.48,-12.14,;21.05,-10.7,;20.07,-9.49,;18.54,-9.73,;17.98,-11.17,;16.54,-11.71,)| Show InChI InChI=1S/C13H16N4O/c1-2-11-12(14-5-1)18-13(15-11)17-9-8-16-6-3-10(17)4-7-16/h1-2,5,10H,3-4,6-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	40.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309885 (2-(6-(Pyrimidine-5-yl)oxazolo[4,5-b]pyridin-2-yl)-...) Show SMILES C1CN2CCC1N(CC2)c1nc2ncc(cc2o1)-c1cncnc1 |TLB:9:6:0.1:4.3,(2.08,-1.36,;1.46,-2.5,;1.54,-4.2,;.55,-4.91,;.85,-3.47,;2.14,-2.77,;3.55,-3.39,;3.91,-4.86,;2.91,-4.14,;4.88,-2.62,;6.37,-3.03,;7.22,-1.75,;8.75,-1.51,;9.31,-.07,;8.33,1.13,;6.81,.89,;6.26,-.54,;4.82,-1.09,;8.81,2.61,;10.33,2.93,;10.82,4.41,;9.78,5.56,;8.25,5.24,;7.77,3.76,)| Show InChI InChI=1S/C17H18N6O/c1-3-22-4-2-14(1)23(6-5-22)17-21-16-15(24-17)7-12(10-20-16)13-8-18-11-19-9-13/h7-11,14H,1-6H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309896 (2-(5-(Piperidin-1-yl)oxazolo[4,5-b]pyridin-2-yl)-2...) Show SMILES C1CCN(CC1)c1ccc2oc(nc2n1)N1CCN2CCC1CC2 |TLB:11:15:20.19:22.23,(5.16,-33.93,;4.36,-35.26,;2.82,-35.24,;2.07,-33.89,;2.85,-32.56,;4.4,-32.58,;.53,-33.87,;-.35,-32.59,;-1.89,-32.71,;-2.56,-34.09,;-4.03,-34.52,;-4.1,-36.05,;-2.64,-36.58,;-1.69,-35.37,;-.15,-35.26,;-5.48,-36.72,;-5.23,-38.21,;-6.18,-37.41,;-7.55,-37.37,;-7.49,-35.67,;-6.79,-34.58,;-6.84,-35.99,;-8.18,-36.59,;-8.6,-38,)| Show InChI InChI=1S/C18H25N5O/c1-2-8-22(9-3-1)16-5-4-15-17(19-16)20-18(24-15)23-13-12-21-10-6-14(23)7-11-21/h4-5,14H,1-3,6-13H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	67.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309881 (2-(5-Methyloxazolo[5,4-b]pyridin-2-yl)-2,5-diazabi...) Show SMILES Cc1ccc2nc(oc2n1)N1CCN2CCC1CC2 |TLB:6:10:15.14:17.18,(8.89,-38.74,;8.34,-40.19,;9.31,-41.4,;8.75,-42.84,;7.22,-43.07,;6.37,-44.35,;4.87,-43.94,;4.81,-42.41,;6.26,-41.86,;6.81,-40.43,;3.54,-44.72,;3.91,-46.18,;2.91,-45.46,;1.53,-45.53,;1.45,-43.83,;2.07,-42.68,;2.13,-44.09,;.84,-44.8,;.54,-46.24,)| Show InChI InChI=1S/C14H18N4O/c1-10-2-3-12-13(15-10)19-14(16-12)18-9-8-17-6-4-11(18)5-7-17/h2-3,11H,4-9H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	88.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Mus musculus (house mouse))	BDBM50309871 (4-Oxazolo[5,4-b]pyridin-2-yl-1,4-diazabicyclo[3.2....) Show SMILES C1CN2CCC1N(CC2)c1nc2cccnc2o1 |TLB:9:6:0.1:4.3,(13.79,-11.99,;13.17,-13.13,;13.25,-14.84,;12.26,-15.55,;12.56,-14.11,;13.86,-13.4,;15.27,-14.03,;15.64,-15.5,;14.63,-14.77,;16.6,-13.25,;18.1,-13.66,;18.95,-12.38,;20.48,-12.14,;21.05,-10.7,;20.07,-9.49,;18.54,-9.73,;17.98,-11.17,;16.54,-11.71,)| Show InChI InChI=1S/C13H16N4O/c1-2-11-12(14-5-1)18-13(15-11)17-9-8-16-6-3-10(17)4-7-16/h1-2,5,10H,3-4,6-9H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	92	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309884 (2-(6-(Pyridin-3-yl)oxazolo[4,5-b]pyridin-2-yl)-2,5...) Show SMILES C1CN2CCC1N(CC2)c1nc2ncc(cc2o1)-c1cccnc1 |TLB:9:6:0.1:4.3,(-8.88,-.92,;-9.5,-2.06,;-9.42,-3.76,;-10.43,-4.47,;-10.12,-3.03,;-8.82,-2.33,;-7.41,-2.95,;-7.05,-4.42,;-8.05,-3.7,;-6.09,-2.18,;-4.59,-2.59,;-3.74,-1.31,;-2.22,-1.07,;-1.65,.37,;-2.63,1.57,;-4.15,1.33,;-4.71,-.1,;-6.15,-.65,;-2.15,3.05,;-3.19,4.2,;-2.71,5.67,;-1.19,6,;-.15,4.85,;-.63,3.37,)| Show InChI InChI=1S/C18H19N5O/c1-2-13(11-19-5-1)14-10-16-17(20-12-14)21-18(24-16)23-9-8-22-6-3-15(23)4-7-22/h1-2,5,10-12,15H,3-4,6-9H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	119	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Mus musculus (house mouse))	BDBM50309881 (2-(5-Methyloxazolo[5,4-b]pyridin-2-yl)-2,5-diazabi...) Show SMILES Cc1ccc2nc(oc2n1)N1CCN2CCC1CC2 |TLB:6:10:15.14:17.18,(8.89,-38.74,;8.34,-40.19,;9.31,-41.4,;8.75,-42.84,;7.22,-43.07,;6.37,-44.35,;4.87,-43.94,;4.81,-42.41,;6.26,-41.86,;6.81,-40.43,;3.54,-44.72,;3.91,-46.18,;2.91,-45.46,;1.53,-45.53,;1.45,-43.83,;2.07,-42.68,;2.13,-44.09,;.84,-44.8,;.54,-46.24,)| Show InChI InChI=1S/C14H18N4O/c1-10-2-3-12-13(15-10)19-14(16-12)18-9-8-17-6-4-11(18)5-7-17/h2-3,11H,4-9H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	126	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Mus musculus (house mouse))	BDBM50309894 (2-(5-Methoxyoxazolo[4,5-b]pyridin-2-yl)-2,5-diazab...) Show SMILES COc1ccc2oc(nc2n1)N1CCN2CCC1CC2 |TLB:7:11:16.15:18.19,(28.27,-20.16,;26.94,-19.37,;25.59,-20.13,;24.61,-18.93,;23.09,-19.17,;22.53,-20.6,;21.09,-21.15,;21.15,-22.68,;22.64,-23.09,;23.5,-21.81,;25.02,-21.58,;19.82,-23.46,;20.19,-24.92,;19.18,-24.2,;17.8,-24.27,;17.73,-22.57,;18.35,-21.42,;18.41,-22.83,;17.11,-23.54,;16.81,-24.98,)| Show InChI InChI=1S/C14H18N4O2/c1-19-12-3-2-11-13(15-12)16-14(20-11)18-9-8-17-6-4-10(18)5-7-17/h2-3,10H,4-9H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	141	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Mus musculus (house mouse))	BDBM50309870 (4-Oxazolo[5,4-c]pyridin-2-yl-1,4-diazabicyclo[3.2....) Show SMILES C1CN2CCC1N(CC2)c1nc2ccncc2o1 |TLB:9:6:0.1:4.3,(2.9,-13.33,;2.28,-14.48,;2.36,-16.19,;1.37,-16.9,;1.67,-15.45,;2.96,-14.75,;4.37,-15.37,;4.74,-16.84,;3.74,-16.12,;5.71,-14.6,;7.2,-15.01,;8.06,-13.72,;9.59,-13.49,;10.15,-12.04,;9.18,-10.83,;7.65,-11.07,;7.09,-12.51,;5.65,-13.06,)| Show InChI InChI=1S/C13H16N4O/c1-4-14-9-12-11(1)15-13(18-12)17-8-7-16-5-2-10(17)3-6-16/h1,4,9-10H,2-3,5-8H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	162	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Mus musculus (house mouse))	BDBM50309888 (4-(6-Chloro-5-methyloxazolo[4,5-b]pyridin-2-yl)-1,...) Show SMILES Cc1nc2nc(oc2cc1Cl)N1CCN2CCC1CC2 |TLB:5:11:16.15:18.19,(1.04,-10.22,;-.49,-10.46,;-1.05,-11.9,;-2.58,-12.13,;-3.43,-13.41,;-4.92,-13,;-4.98,-11.47,;-3.54,-10.92,;-2.99,-9.49,;-1.46,-9.25,;-.9,-7.79,;-6.25,-13.78,;-5.89,-15.24,;-6.89,-14.52,;-8.27,-14.59,;-8.34,-12.89,;-7.73,-11.74,;-7.66,-13.15,;-8.96,-13.86,;-9.26,-15.3,)| Show InChI InChI=1S/C14H17ClN4O/c1-9-11(15)8-12-13(16-9)17-14(20-12)19-7-6-18-4-2-10(19)3-5-18/h8,10H,2-7H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	244	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Mus musculus (house mouse))	BDBM50309861 (4-(5-Methyloxazolo[4,5-b]pyridin-2-yl)-1,4-diazabi...) Show SMILES Cc1ccc2oc(nc2n1)N1CCN2CCC1CC2 |TLB:6:10:15.14:17.18,(20.91,-29.51,;19.38,-29.74,;18.4,-28.53,;16.88,-28.77,;16.32,-30.21,;14.88,-30.76,;14.94,-32.29,;16.44,-32.7,;17.29,-31.42,;18.82,-31.19,;13.61,-33.07,;13.98,-34.53,;12.97,-33.81,;11.6,-33.88,;11.52,-32.18,;12.14,-31.03,;12.2,-32.44,;10.91,-33.15,;10.61,-34.59,)| Show InChI InChI=1S/C14H18N4O/c1-10-2-3-12-13(15-10)16-14(19-12)18-9-8-17-6-4-11(18)5-7-17/h2-3,11H,4-9H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	269	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309870 (4-Oxazolo[5,4-c]pyridin-2-yl-1,4-diazabicyclo[3.2....) Show SMILES C1CN2CCC1N(CC2)c1nc2ccncc2o1 |TLB:9:6:0.1:4.3,(2.9,-13.33,;2.28,-14.48,;2.36,-16.19,;1.37,-16.9,;1.67,-15.45,;2.96,-14.75,;4.37,-15.37,;4.74,-16.84,;3.74,-16.12,;5.71,-14.6,;7.2,-15.01,;8.06,-13.72,;9.59,-13.49,;10.15,-12.04,;9.18,-10.83,;7.65,-11.07,;7.09,-12.51,;5.65,-13.06,)| Show InChI InChI=1S/C13H16N4O/c1-4-14-9-12-11(1)15-13(18-12)17-8-7-16-5-2-10(17)3-6-16/h1,4,9-10H,2-3,5-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	309	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50309869 (4-Oxazolo[4,5-c]pyridin-2-yl-1,4-diazabicyclo[3.2....) Show SMILES C1CN2CCC1N(CC2)c1nc2cnccc2o1 |TLB:9:6:0.1:4.3,(-8.72,-14.81,;-9.34,-15.95,;-9.26,-17.66,;-10.25,-18.37,;-9.95,-16.93,;-8.65,-16.22,;-7.24,-16.85,;-6.87,-18.32,;-7.88,-17.59,;-5.91,-16.07,;-4.41,-16.48,;-3.56,-15.2,;-2.03,-14.96,;-1.46,-13.52,;-2.44,-12.31,;-3.97,-12.55,;-4.53,-13.99,;-5.97,-14.53,)| Show InChI InChI=1S/C13H16N4O/c1-4-14-9-11-12(1)18-13(15-11)17-8-7-16-5-2-10(17)3-6-16/h1,4,9-10H,2-3,5-8H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	312	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Mus musculus (house mouse))	BDBM50309887 (4-(6-Fluoro-5-methyloxazolo[4,5-b]pyridin-2-yl)-1,...) Show SMILES Cc1nc2nc(oc2cc1F)N1CCN2CCC1CC2 |TLB:5:11:16.15:18.19,(31.85,-.7,;30.32,-.94,;29.76,-2.38,;28.23,-2.62,;27.38,-3.9,;25.89,-3.49,;25.83,-1.95,;27.27,-1.41,;27.82,.03,;29.35,.27,;29.91,1.72,;24.56,-4.26,;24.92,-5.73,;23.92,-5.01,;22.54,-5.08,;22.47,-3.37,;23.08,-2.23,;23.15,-3.64,;21.85,-4.34,;21.55,-5.78,)| Show InChI InChI=1S/C14H17FN4O/c1-9-11(15)8-12-13(16-9)17-14(20-12)19-7-6-18-4-2-10(19)3-5-18/h8,10H,2-7H2,1H3	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	547	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 3A (Mus musculus (house mouse))	BDBM50309868 (4-Oxazolo[4,5-b]pyridin-2-yl-1,4-diazabicyclo[3.2....) Show SMILES C1CN2CCC1N(CC2)c1nc2ncccc2o1 |TLB:9:6:0.1:4.3,(27.22,-2.94,;26.61,-4.09,;26.68,-5.8,;25.69,-6.51,;25.99,-5.06,;27.29,-4.36,;28.7,-4.98,;29.07,-6.45,;28.06,-5.73,;30.03,-4.21,;31.53,-4.62,;32.38,-3.34,;33.91,-3.1,;34.48,-1.66,;33.5,-.45,;31.97,-.69,;31.42,-2.12,;29.97,-2.67,)| Show InChI InChI=1S/C13H16N4O/c1-2-11-12(14-5-1)15-13(18-11)17-9-8-16-6-3-10(17)4-7-16/h1-2,5,10H,3-4,6-9H2	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	579	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [3H]LY278584 from mouse 5HT3 receptor expressed in HEK293 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair
Neuronal acetylcholine receptor subunit alpha-7 (Rattus norvegicus (Rat))	BDBM50296730 (CHEMBL563848 | phenyl 1,4-diazabicyclo[3.2.2]nonan...) Show SMILES O=C(Oc1ccccc1)N1CCN2CCC1CC2 |TLB:1:9:14.13:16.17,(-5.08,4.31,;-5.08,2.76,;-3.74,1.99,;-2.4,2.77,;-1.06,2,;.28,2.77,;.27,4.32,;-1.08,5.09,;-2.41,4.31,;-6.42,1.98,;-6.05,.51,;-7.06,1.23,;-8.44,1.16,;-8.52,2.88,;-7.9,4.03,;-7.83,2.61,;-9.13,1.9,;-9.44,.45,)| Show InChI InChI=1S/C14H18N2O2/c17-14(18-13-4-2-1-3-5-13)16-11-10-15-8-6-12(16)7-9-15/h1-5,12H,6-11H2	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	739	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Displacement of [125I]BTX from rat alpha7 nicotinic acetylcholine receptor expressed in GH4C1 cells				J Med Chem 53: 1222-37 (2010) Article DOI: 10.1021/jm9015075 BindingDB Entry DOI: 10.7270/Q2QN66W3
					More data for this Ligand-Target Pair

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