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Compile Data Set for Download or QSAR

Found 117 hits Enz. Inhib. hit(s) with all data for entry = 50031259   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310000
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES Cc1cc(Br)ccc1CNC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccccc1Cl
Show InChI InChI=1S/C27H21Br2ClN6O/c1-17-12-21(29)11-8-19(17)13-32-27(37)25-22(14-35-16-31-15-33-35)26(18-6-9-20(28)10-7-18)36(34-25)24-5-3-2-4-23(24)30/h2-12,15-16H,13-14H2,1H3,(H,32,37)
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n/an/a 1.10n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309995
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES Cc1cc(Br)ccc1CNC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C27H20Br2Cl2N6O/c1-16-10-20(29)7-4-18(16)12-33-27(38)25-22(13-36-15-32-14-34-36)26(17-2-5-19(28)6-3-17)37(35-25)24-9-8-21(30)11-23(24)31/h2-11,14-15H,12-13H2,1H3,(H,33,38)
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n/an/a 1.40n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310005
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES Clc1ccccc1-n1nc(C(=O)NC2CCCCC2)c(Cn2cncn2)c1-c1ccc(Br)cc1
Show InChI InChI=1S/C25H24BrClN6O/c26-18-12-10-17(11-13-18)24-20(14-32-16-28-15-29-32)23(25(34)30-19-6-2-1-3-7-19)31-33(24)22-9-5-4-8-21(22)27/h4-5,8-13,15-16,19H,1-3,6-7,14H2,(H,30,34)
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n/an/a 1.60n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310003
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES Clc1ccc(cc1)C1(CC1)NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccccc1Cl
Show InChI InChI=1S/C28H21BrCl2N6O/c29-20-9-5-18(6-10-20)26-22(15-36-17-32-16-33-36)25(35-37(26)24-4-2-1-3-23(24)31)27(38)34-28(13-14-28)19-7-11-21(30)12-8-19/h1-12,16-17H,13-15H2,(H,34,38)
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n/an/a 1.70n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309988
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-N-(1-(4-bromophe...)
Show SMILES Cc1cc(Br)ccc1CNC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccccc1Cl
Show InChI InChI=1S/C27H21BrCl2N6O/c1-17-12-20(28)9-6-19(17)13-32-27(37)25-22(14-35-16-31-15-33-35)26(18-7-10-21(29)11-8-18)36(34-25)24-5-3-2-4-23(24)30/h2-12,15-16H,13-14H2,1H3,(H,32,37)
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n/an/a 1.80n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310002
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES Clc1ccccc1-n1nc(C(=O)NC2CC2c2ccccc2)c(Cn2cncn2)c1-c1ccc(Br)cc1
Show InChI InChI=1S/C28H22BrClN6O/c29-20-12-10-19(11-13-20)27-22(15-35-17-31-16-32-35)26(34-36(27)25-9-5-4-8-23(25)30)28(37)33-24-14-21(24)18-6-2-1-3-7-18/h1-13,16-17,21,24H,14-15H2,(H,33,37)
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n/an/a 1.98n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309989
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-1-(2-chloropheny...)
Show SMILES Cc1cc(Cl)cc(Cl)c1CNC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccccc1Cl
Show InChI InChI=1S/C27H20Cl4N6O/c1-16-10-19(29)11-23(31)20(16)12-33-27(38)25-21(13-36-15-32-14-34-36)26(17-6-8-18(28)9-7-17)37(35-25)24-5-3-2-4-22(24)30/h2-11,14-15H,12-13H2,1H3,(H,33,38)
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n/an/a 2n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310008
PNG
((4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromopheny...)
Show SMILES Cc1cccc(N2CCN(CC2)C(=O)c2nn(c(c2Cn2cncn2)-c2ccc(Br)cc2)-c2ccccc2Cl)c1C
Show InChI InChI=1S/C31H29BrClN7O/c1-21-6-5-9-27(22(21)2)37-14-16-38(17-15-37)31(41)29-25(18-39-20-34-19-35-39)30(23-10-12-24(32)13-11-23)40(36-29)28-8-4-3-7-26(28)33/h3-13,19-20H,14-18H2,1-2H3
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n/an/a 2.07n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309996
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES Cc1cc(Cl)cc(Cl)c1CNC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C27H19BrCl4N6O/c1-15-8-19(30)10-22(31)20(15)11-34-27(39)25-21(12-37-14-33-13-35-37)26(16-2-4-17(28)5-3-16)38(36-25)24-7-6-18(29)9-23(24)32/h2-10,13-14H,11-12H2,1H3,(H,34,39)
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n/an/a 2.20n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310001
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES Cc1cc(Cl)cc(Cl)c1CNC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccccc1Cl
Show InChI InChI=1S/C27H20BrCl3N6O/c1-16-10-19(29)11-23(31)20(16)12-33-27(38)25-21(13-36-15-32-14-34-36)26(17-6-8-18(28)9-7-17)37(35-25)24-5-3-2-4-22(24)30/h2-11,14-15H,12-13H2,1H3,(H,33,38)
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n/an/a 2.20n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310007
PNG
((4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromopheny...)
Show SMILES Clc1cccc(N2CCN(CC2)C(=O)c2nn(c(c2Cn2cncn2)-c2ccc(Br)cc2)-c2ccccc2Cl)c1Cl
Show InChI InChI=1S/C29H23BrCl3N7O/c30-20-10-8-19(9-11-20)28-21(16-39-18-34-17-35-39)27(36-40(28)24-6-2-1-4-22(24)31)29(41)38-14-12-37(13-15-38)25-7-3-5-23(32)26(25)33/h1-11,17-18H,12-16H2
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n/an/a 2.22n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310006
PNG
((4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromopheny...)
Show SMILES Clc1cccc(c1)N1CCN(CC1)C(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccccc1Cl
Show InChI InChI=1S/C29H24BrCl2N7O/c30-21-10-8-20(9-11-21)28-24(17-38-19-33-18-34-38)27(35-39(28)26-7-2-1-6-25(26)32)29(40)37-14-12-36(13-15-37)23-5-3-4-22(31)16-23/h1-11,16,18-19H,12-15,17H2
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n/an/a 2.28n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Homo sapiens (Human))
BDBM50310000
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES Cc1cc(Br)ccc1CNC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccccc1Cl
Show InChI InChI=1S/C27H21Br2ClN6O/c1-17-12-21(29)11-8-19(17)13-32-27(37)25-22(14-35-16-31-15-33-35)26(18-6-9-20(28)10-7-18)36(34-25)24-5-3-2-4-23(24)30/h2-12,15-16H,13-14H2,1H3,(H,32,37)
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n/an/a 2.51n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Inverse agonist activity at human recombinant CB1 receptor expressed in CHO cells by luciferase reporter gene assay


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309980
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chloropheny...)
Show SMILES Cc1cc(Cl)cc(Cl)c1CNC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C27H19Cl5N6O/c1-15-8-19(30)10-22(31)20(15)11-34-27(39)25-21(12-37-14-33-13-35-37)26(16-2-4-17(28)5-3-16)38(36-25)24-7-6-18(29)9-23(24)32/h2-10,13-14H,11-12H2,1H3,(H,34,39)
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n/an/a 2.60n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309979
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-N-(1-(4-bromophe...)
Show SMILES Cc1cc(Br)ccc1CNC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C27H20BrCl3N6O/c1-16-10-19(28)5-2-18(16)12-33-27(38)25-22(13-36-15-32-14-34-36)26(17-3-6-20(29)7-4-17)37(35-25)24-9-8-21(30)11-23(24)31/h2-11,14-15H,12-13H2,1H3,(H,33,38)
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n/an/a 2.60n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310036
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES Clc1ccccc1-n1nc(C(=O)NC2CCCCCC2)c(Cn2cncn2)c1-c1ccc(Br)cc1
Show InChI InChI=1S/C26H26BrClN6O/c27-19-13-11-18(12-14-19)25-21(15-33-17-29-16-30-33)24(26(35)31-20-7-3-1-2-4-8-20)32-34(25)23-10-6-5-9-22(23)28/h5-6,9-14,16-17,20H,1-4,7-8,15H2,(H,31,35)
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n/an/a 2.70n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309998
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES Clc1ccc(cc1)C1(CC1)NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C28H20BrCl3N6O/c29-19-5-1-17(2-6-19)26-22(14-37-16-33-15-34-37)25(36-38(26)24-10-9-21(31)13-23(24)32)27(39)35-28(11-12-28)18-3-7-20(30)8-4-18/h1-10,13,15-16H,11-12,14H2,(H,35,39)
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n/an/a 2.80n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310040
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES CC(C)(C)NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C23H21BrCl2N6O/c1-23(2,3)29-22(33)20-17(11-31-13-27-12-28-31)21(14-4-6-15(24)7-5-14)32(30-20)19-9-8-16(25)10-18(19)26/h4-10,12-13H,11H2,1-3H3,(H,29,33)
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n/an/a 2.90n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309994
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES Cc1cc(Cl)cc(C)c1CNC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C28H22BrCl3N6O/c1-16-9-21(31)10-17(2)22(16)12-34-28(39)26-23(13-37-15-33-14-35-37)27(18-3-5-19(29)6-4-18)38(36-26)25-8-7-20(30)11-24(25)32/h3-11,14-15H,12-13H2,1-2H3,(H,34,39)
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n/an/a 2.99n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310070
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chloropheny...)
Show SMILES CCC(C)(C)NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C24H23Cl3N6O/c1-4-24(2,3)30-23(34)21-18(12-32-14-28-13-29-32)22(15-5-7-16(25)8-6-15)33(31-21)20-10-9-17(26)11-19(20)27/h5-11,13-14H,4,12H2,1-3H3,(H,30,34)
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n/an/a 3.01n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310049
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES FC(F)(F)C1(CC1)NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C23H16BrCl2F3N6O/c24-14-3-1-13(2-4-14)20-16(10-34-12-30-11-31-34)19(21(36)32-22(7-8-22)23(27,28)29)33-35(20)18-6-5-15(25)9-17(18)26/h1-6,9,11-12H,7-8,10H2,(H,32,36)
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n/an/a 3.31n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309978
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chloropheny...)
Show SMILES Cc1cc(Cl)cc(C)c1CNC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C28H22Cl4N6O/c1-16-9-21(31)10-17(2)22(16)12-34-28(39)26-23(13-37-15-33-14-35-37)27(18-3-5-19(29)6-4-18)38(36-26)25-8-7-20(30)11-24(25)32/h3-11,14-15H,12-13H2,1-2H3,(H,34,39)
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n/an/a 3.33n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310039
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES CCC(C)(C)NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C24H23BrCl2N6O/c1-4-24(2,3)30-23(34)21-18(12-32-14-28-13-29-32)22(15-5-7-16(25)8-6-15)33(31-21)20-10-9-17(26)11-19(20)27/h5-11,13-14H,4,12H2,1-3H3,(H,30,34)
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n/an/a 3.67n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309975
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chloropheny...)
Show SMILES Clc1ccc(cc1)-c1c(Cn2cncn2)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NC1CCCCC1
Show InChI InChI=1S/C25H23Cl3N6O/c26-17-8-6-16(7-9-17)24-20(13-33-15-29-14-30-33)23(25(35)31-19-4-2-1-3-5-19)32-34(24)22-11-10-18(27)12-21(22)28/h6-12,14-15,19H,1-5,13H2,(H,31,35)
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n/an/a 3.77n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310013
PNG
((4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromopheny...)
Show SMILES Cc1cccc(N2CCN(CC2)C(=O)c2nn(c(c2Cn2cncn2)-c2ccc(Br)cc2)-c2ccc(Cl)cc2Cl)c1C
Show InChI InChI=1S/C31H28BrCl2N7O/c1-20-4-3-5-27(21(20)2)38-12-14-39(15-13-38)31(42)29-25(17-40-19-35-18-36-40)30(22-6-8-23(32)9-7-22)41(37-29)28-11-10-24(33)16-26(28)34/h3-11,16,18-19H,12-15,17H2,1-2H3
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n/an/a 3.80n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309977
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chloropheny...)
Show SMILES Clc1ccc(cc1)-c1c(Cn2cncn2)c(nn1-c1ccc(Cl)cc1Cl)C(=O)N1CCCCC1
Show InChI InChI=1S/C24H21Cl3N6O/c25-17-6-4-16(5-7-17)23-19(13-32-15-28-14-29-32)22(24(34)31-10-2-1-3-11-31)30-33(23)21-9-8-18(26)12-20(21)27/h4-9,12,14-15H,1-3,10-11,13H2
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n/an/a 3.83n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310048
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES FC(F)(F)C1(CCC1)NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C24H18BrCl2F3N6O/c25-15-4-2-14(3-5-15)21-17(11-35-13-31-12-32-35)20(22(37)33-23(8-1-9-23)24(28,29)30)34-36(21)19-7-6-16(26)10-18(19)27/h2-7,10,12-13H,1,8-9,11H2,(H,33,37)
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n/an/a 3.87n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310020
PNG
((4-((1H-1,2,4-Triazol-1-yl)methyl)-1-(2-chlorophen...)
Show SMILES Clc1ccc(cc1)-c1c(Cn2cncn2)c(nn1-c1ccccc1Cl)C(=O)N1CCN(CC1)c1cccc(Cl)c1
Show InChI InChI=1S/C29H24Cl3N7O/c30-21-10-8-20(9-11-21)28-24(17-38-19-33-18-34-38)27(35-39(28)26-7-2-1-6-25(26)32)29(40)37-14-12-36(13-15-37)23-5-3-4-22(31)16-23/h1-11,16,18-19H,12-15,17H2
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n/an/a 4.08n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310038
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES CC(NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccc(Cl)cc1Cl)C(C)(C)C
Show InChI InChI=1S/C25H25BrCl2N6O/c1-15(25(2,3)4)31-24(35)22-19(12-33-14-29-13-30-33)23(16-5-7-17(26)8-6-16)34(32-22)21-10-9-18(27)11-20(21)28/h5-11,13-15H,12H2,1-4H3,(H,31,35)
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n/an/a 4.10n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310052
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)NC2CCCCC2)c(Cn2cncn2)c1-c1ccc(Br)cc1
Show InChI InChI=1S/C25H23BrCl2N6O/c26-17-8-6-16(7-9-17)24-20(13-33-15-29-14-30-33)23(25(35)31-19-4-2-1-3-5-19)32-34(24)22-11-10-18(27)12-21(22)28/h6-12,14-15,19H,1-5,13H2,(H,31,35)
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n/an/a 4.38n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310067
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chloropheny...)
Show SMILES FC(F)(F)C1(CC1)NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C23H16Cl3F3N6O/c24-14-3-1-13(2-4-14)20-16(10-34-12-30-11-31-34)19(21(36)32-22(7-8-22)23(27,28)29)33-35(20)18-6-5-15(25)9-17(18)26/h1-6,9,11-12H,7-8,10H2,(H,32,36)
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n/an/a 4.5n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM21278
PNG
(5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl...)
Show SMILES Cc1c(nn(c1-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl)C(=O)NN1CCCCC1
Show InChI InChI=1S/C22H21Cl3N4O/c1-14-20(22(30)27-28-11-3-2-4-12-28)26-29(19-10-9-17(24)13-18(19)25)21(14)15-5-7-16(23)8-6-15/h5-10,13H,2-4,11-12H2,1H3,(H,27,30)
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n/an/a 4.53n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310066
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chloropheny...)
Show SMILES FC(F)(F)C1(CCC1)NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C24H18Cl3F3N6O/c25-15-4-2-14(3-5-15)21-17(11-35-13-31-12-32-35)20(22(37)33-23(8-1-9-23)24(28,29)30)34-36(21)19-7-6-16(26)10-18(19)27/h2-7,10,12-13H,1,8-9,11H2,(H,33,37)
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n/an/a 4.67n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310058
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-1-(2-chloropheny...)
Show SMILES FC(F)(F)C1(CC1)NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccccc1Cl
Show InChI InChI=1S/C23H17Cl2F3N6O/c24-15-7-5-14(6-8-15)20-16(11-33-13-29-12-30-33)19(21(35)31-22(9-10-22)23(26,27)28)32-34(20)18-4-2-1-3-17(18)25/h1-8,12-13H,9-11H2,(H,31,35)
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n/an/a 4.75n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309993
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-N-tert-butyl-5-(...)
Show SMILES CC(C)(C)NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccc(Cl)cc1Cl
Show InChI InChI=1S/C23H21Cl3N6O/c1-23(2,3)29-22(33)20-17(11-31-13-27-12-28-31)21(14-4-6-15(24)7-5-14)32(30-20)19-9-8-16(25)10-18(19)26/h4-10,12-13H,11H2,1-3H3,(H,29,33)
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n/an/a 4.90n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309982
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chloropheny...)
Show SMILES Clc1ccc(cc1)-c1c(Cn2cncn2)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NC1(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C28H20Cl4N6O/c29-19-5-1-17(2-6-19)26-22(14-37-16-33-15-34-37)25(36-38(26)24-10-9-21(31)13-23(24)32)27(39)35-28(11-12-28)18-3-7-20(30)8-4-18/h1-10,13,15-16H,11-12,14H2,(H,35,39)
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n/an/a 5.09n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309981
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chloropheny...)
Show SMILES Clc1ccc(cc1)-c1c(Cn2cncn2)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NC1(CC1)c1ccccc1
Show InChI InChI=1S/C28H21Cl3N6O/c29-20-8-6-18(7-9-20)26-22(15-36-17-32-16-33-36)25(35-37(26)24-11-10-21(30)14-23(24)31)27(38)34-28(12-13-28)19-4-2-1-3-5-19/h1-11,14,16-17H,12-13,15H2,(H,34,38)
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n/an/a 5.10n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310054
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)N2CCCCC2)c(Cn2cncn2)c1-c1ccc(Br)cc1
Show InChI InChI=1S/C24H21BrCl2N6O/c25-17-6-4-16(5-7-17)23-19(13-32-15-28-14-29-32)22(24(34)31-10-2-1-3-11-31)30-33(23)21-9-8-18(26)12-20(21)27/h4-9,12,14-15H,1-3,10-11,13H2
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n/an/a 5.11n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310057
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-1-(2-chloropheny...)
Show SMILES FC(F)(F)C1(CCC1)NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccccc1Cl
Show InChI InChI=1S/C24H19Cl2F3N6O/c25-16-8-6-15(7-9-16)21-17(12-34-14-30-13-31-34)20(33-35(21)19-5-2-1-4-18(19)26)22(36)32-23(10-3-11-23)24(27,28)29/h1-2,4-9,13-14H,3,10-12H2,(H,32,36)
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n/an/a 5.14n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310037
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES Clc1ccccc1-n1nc(C(=O)N2CCCCC2)c(Cn2cncn2)c1-c1ccc(Br)cc1
Show InChI InChI=1S/C24H22BrClN6O/c25-18-10-8-17(9-11-18)23-19(14-31-16-27-15-28-31)22(24(33)30-12-4-1-5-13-30)29-32(23)21-7-3-2-6-20(21)26/h2-3,6-11,15-16H,1,4-5,12-14H2
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n/an/a 5.23n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310026
PNG
((4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-chlorophen...)
Show SMILES Clc1ccc(cc1)-c1c(Cn2cncn2)c(nn1-c1ccc(Cl)cc1Cl)C(=O)N1CCN(CC1)c1cccc(Cl)c1Cl
Show InChI InChI=1S/C29H22Cl5N7O/c30-19-6-4-18(5-7-19)28-21(15-40-17-35-16-36-40)27(37-41(28)24-9-8-20(31)14-23(24)33)29(42)39-12-10-38(11-13-39)25-3-1-2-22(32)26(25)34/h1-9,14,16-17H,10-13,15H2
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n/an/a 5.5n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310014
PNG
((4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromopheny...)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)N2CCN(CC2)c2cccc(Cl)c2Cl)c(Cn2cncn2)c1-c1ccc(Br)cc1
Show InChI InChI=1S/C29H22BrCl4N7O/c30-19-6-4-18(5-7-19)28-21(15-40-17-35-16-36-40)27(37-41(28)24-9-8-20(31)14-23(24)33)29(42)39-12-10-38(11-13-39)25-3-1-2-22(32)26(25)34/h1-9,14,16-17H,10-13,15H2
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n/an/a 5.74n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309990
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-1-(2-chloropheny...)
Show SMILES Clc1ccc(cc1)-c1c(Cn2cncn2)c(nn1-c1ccccc1Cl)C(=O)NC1(CC1)c1ccccc1
Show InChI InChI=1S/C28H22Cl2N6O/c29-21-12-10-19(11-13-21)26-22(16-35-18-31-17-32-35)25(34-36(26)24-9-5-4-8-23(24)30)27(37)33-28(14-15-28)20-6-2-1-3-7-20/h1-13,17-18H,14-16H2,(H,33,37)
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n/an/a 5.81n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310031
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES CC(NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccccc1Cl)C(C)(C)C
Show InChI InChI=1S/C25H26BrClN6O/c1-16(25(2,3)4)30-24(34)22-19(13-32-15-28-14-29-32)23(17-9-11-18(26)12-10-17)33(31-22)21-8-6-5-7-20(21)27/h5-12,14-16H,13H2,1-4H3,(H,30,34)
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n/an/a 6n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310019
PNG
((4-((1H-1,2,4-Triazol-1-yl)methyl)-1-(2-chlorophen...)
Show SMILES Cc1cccc(N2CCN(CC2)C(=O)c2nn(c(c2Cn2cncn2)-c2ccc(Cl)cc2)-c2ccccc2Cl)c1C
Show InChI InChI=1S/C31H29Cl2N7O/c1-21-6-5-9-27(22(21)2)37-14-16-38(17-15-37)31(41)29-25(18-39-20-34-19-35-39)30(23-10-12-24(32)13-11-23)40(36-29)28-8-4-3-7-26(28)33/h3-13,19-20H,14-18H2,1-2H3
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n/an/a 6.09n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309999
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromophenyl...)
Show SMILES Cc1cccc(C)c1CNC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Br)cc1)-c1ccccc1Cl
Show InChI InChI=1S/C28H24BrClN6O/c1-18-6-5-7-19(2)22(18)14-32-28(37)26-23(15-35-17-31-16-33-35)27(20-10-12-21(29)13-11-20)36(34-26)25-9-4-3-8-24(25)30/h3-13,16-17H,14-15H2,1-2H3,(H,32,37)
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n/an/a 6.10n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310055
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-1-(2-chloropheny...)
Show SMILES CC(NC(=O)c1nn(c(c1Cn1cncn1)-c1ccc(Cl)cc1)-c1ccccc1Cl)C(C)(C)C
Show InChI InChI=1S/C25H26Cl2N6O/c1-16(25(2,3)4)30-24(34)22-19(13-32-15-28-14-29-32)23(17-9-11-18(26)12-10-17)33(31-22)21-8-6-5-7-20(21)27/h5-12,14-16H,13H2,1-4H3,(H,30,34)
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n/an/a 6.22n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310061
PNG
(4-((1H-1,2,4-Triazol-1-yl)methyl)-1-(2-chloropheny...)
Show SMILES Clc1ccc(cc1)-c1c(Cn2cncn2)c(nn1-c1ccccc1Cl)C(=O)NC1CCCCC1
Show InChI InChI=1S/C25H24Cl2N6O/c26-18-12-10-17(11-13-18)24-20(14-32-16-28-15-29-32)23(25(34)30-19-6-2-1-3-7-19)31-33(24)22-9-5-4-8-21(22)27/h4-5,8-13,15-16,19H,1-3,6-7,14H2,(H,30,34)
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n/an/a 6.60n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50309976
PNG
(4-((1H-1,2,4-triazol-1-yl)methyl)-5-(4-chloropheny...)
Show SMILES Clc1ccc(cc1)-c1c(Cn2cncn2)c(nn1-c1ccc(Cl)cc1Cl)C(=O)NC1CCCC1
Show InChI InChI=1S/C24H21Cl3N6O/c25-16-7-5-15(6-8-16)23-19(12-32-14-28-13-29-32)22(24(34)30-18-3-1-2-4-18)31-33(23)21-10-9-17(26)11-20(21)27/h5-11,13-14,18H,1-4,12H2,(H,30,34)
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n/an/a 6.90n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
Cannabinoid receptor 1


(Rattus norvegicus (rat))
BDBM50310015
PNG
((4-((1H-1,2,4-Triazol-1-yl)methyl)-5-(4-bromopheny...)
Show SMILES Clc1ccc(c(Cl)c1)-n1nc(C(=O)N2CCN(CC2)c2cccc(Cl)c2)c(Cn2cncn2)c1-c1ccc(Br)cc1
Show InChI InChI=1S/C29H23BrCl3N7O/c30-20-6-4-19(5-7-20)28-24(16-39-18-34-17-35-39)27(36-40(28)26-9-8-22(32)15-25(26)33)29(41)38-12-10-37(11-13-38)23-3-1-2-21(31)14-23/h1-9,14-15,17-18H,10-13,16H2
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n/an/a 7.22n/an/an/an/an/an/a



Green Cross Corporation

Curated by ChEMBL


Assay Description
Displacement of [3H]CP55,940 from CB1 receptor in Sprague-Dawley rat cerebellar membrane


Bioorg Med Chem 18: 1149-62 (2010)


Article DOI: 10.1016/j.bmc.2009.12.040
BindingDB Entry DOI: 10.7270/Q2TD9XG2
More data for this
Ligand-Target Pair
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