Compile Data Set for Download or QSAR

Found 143 hits Enz. Inhib. hit(s) with all data for entry = 50031570   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315482 (CHEMBL1093897 | N-(3-chlorophenylsulfonyl)-3-(3,3-...) Show SMILES FC1(F)C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C28H19ClF2N2O4S/c29-22-8-4-9-23(16-22)38(36,37)32-25(34)14-13-20-7-3-10-24-26(20)33(27(35)28(24,30)31)17-18-11-12-19-5-1-2-6-21(19)15-18/h1-16H,17H2,(H,32,34)/b14-13+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.100	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315471 (3-(1-(2,4-dichlorobenzyl)-3,3-difluoro-2-oxoindoli...) Show SMILES Fc1cc(F)c(cc1F)S(=O)(=O)NC(=O)\C=C\c1cccc2c1N(Cc1ccc(Cl)cc1Cl)C(=O)C2(F)F Show InChI InChI=1S/C24H13Cl2F5N2O4S/c25-14-6-4-13(16(26)8-14)11-33-22-12(2-1-3-15(22)24(30,31)23(33)35)5-7-21(34)32-38(36,37)20-10-18(28)17(27)9-19(20)29/h1-10H,11H2,(H,32,34)/b7-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315493 (3-(1-(2,4-dichlorobenzyl)-2-oxoindolin-7-yl)-N-(2,...) Show SMILES Fc1cc(F)c(cc1F)S(=O)(=O)NC(=O)\C=C\c1cccc2CC(=O)N(Cc3ccc(Cl)cc3Cl)c12 Show InChI InChI=1S/C24H15Cl2F3N2O4S/c25-16-6-4-15(17(26)9-16)12-31-23(33)8-14-3-1-2-13(24(14)31)5-7-22(32)30-36(34,35)21-11-19(28)18(27)10-20(21)29/h1-7,9-11H,8,12H2,(H,30,32)/b7-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315474 (CHEMBL1089095 | N-(3-chlorophenylsulfonyl)-3-(1-(2...) Show SMILES FC1(F)C(=O)N(Cc2ccc(Cl)cc2Cl)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C24H15Cl3F2N2O4S/c25-16-4-2-5-18(11-16)36(34,35)30-21(32)10-8-14-3-1-6-19-22(14)31(23(33)24(19,28)29)13-15-7-9-17(26)12-20(15)27/h1-12H,13H2,(H,30,32)/b10-8+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315472 (3-(1-(2,4-dichlorobenzyl)-3,3-difluoro-2-oxoindoli...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)\C=C\c1cccc2c1N(Cc1ccc(Cl)cc1Cl)C(=O)C2(F)F Show InChI InChI=1S/C24H14Cl2F4N2O4S/c25-15-6-4-14(18(26)10-15)12-32-22-13(2-1-3-17(22)24(29,30)23(32)34)5-9-21(33)31-37(35,36)16-7-8-19(27)20(28)11-16/h1-11H,12H2,(H,31,33)/b9-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315476 (3-(1-(2,4-dichlorobenzyl)-3,3-difluoro-2-oxoindoli...) Show SMILES Fc1ccc(cc1)S(=O)(=O)NC(=O)\C=C\c1cccc2c1N(Cc1ccc(Cl)cc1Cl)C(=O)C2(F)F Show InChI InChI=1S/C24H15Cl2F3N2O4S/c25-16-6-4-15(20(26)12-16)13-31-22-14(2-1-3-19(22)24(28,29)23(31)33)5-11-21(32)30-36(34,35)18-9-7-17(27)8-10-18/h1-12H,13H2,(H,30,32)/b11-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315473 (3-(1-(2,4-dichlorobenzyl)-3,3-difluoro-2-oxoindoli...) Show SMILES FC1(F)C(=O)N(Cc2ccc(Cl)cc2Cl)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C24H14Cl4F2N2O4S/c25-15-6-4-14(19(27)10-15)12-32-22-13(2-1-3-17(22)24(29,30)23(32)34)5-9-21(33)31-37(35,36)16-7-8-18(26)20(28)11-16/h1-11H,12H2,(H,31,33)/b9-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315480 (3-(3,3-difluoro-1-(naphthalen-2-ylmethyl)-2-oxoind...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)\C=C\c1cccc2c1N(Cc1ccc3ccccc3c1)C(=O)C2(F)F Show InChI InChI=1S/C28H18F4N2O4S/c29-23-12-11-21(15-24(23)30)39(37,38)33-25(35)13-10-19-6-3-7-22-26(19)34(27(36)28(22,31)32)16-17-8-9-18-4-1-2-5-20(18)14-17/h1-15H,16H2,(H,33,35)/b13-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.200	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315479 (3-(3,3-difluoro-1-(naphthalen-2-ylmethyl)-2-oxoind...) Show SMILES Fc1cc(F)c(cc1F)S(=O)(=O)NC(=O)\C=C\c1cccc2c1N(Cc1ccc3ccccc3c1)C(=O)C2(F)F Show InChI InChI=1S/C28H17F5N2O4S/c29-21-13-23(31)24(14-22(21)30)40(38,39)34-25(36)11-10-18-6-3-7-20-26(18)35(27(37)28(20,32)33)15-16-8-9-17-4-1-2-5-19(17)12-16/h1-14H,15H2,(H,34,36)/b11-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315528 (3-(3-methyl-1-(naphthalen-2-ylmethyl)-2-oxoindolin...) Show SMILES CC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cc(F)c(F)cc1F Show InChI InChI=1S/C29H21F3N2O4S/c1-17-22-8-4-7-20(11-12-27(35)33-39(37,38)26-15-24(31)23(30)14-25(26)32)28(22)34(29(17)36)16-18-9-10-19-5-2-3-6-21(19)13-18/h2-15,17H,16H2,1H3,(H,33,35)/b12-11+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315498 (3-(1-(naphthalen-2-ylmethyl)-2-oxoindolin-7-yl)-N-...) Show SMILES Fc1cc(F)c(cc1F)S(=O)(=O)NC(=O)\C=C\c1cccc2CC(=O)N(Cc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C28H19F3N2O4S/c29-22-14-24(31)25(15-23(22)30)38(36,37)32-26(34)11-10-19-6-3-7-21-13-27(35)33(28(19)21)16-17-8-9-18-4-1-2-5-20(18)12-17/h1-12,14-15H,13,16H2,(H,32,34)/b11-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315481 (CHEMBL1090222 | N-(3,4-dichlorophenylsulfonyl)-3-(...) Show SMILES FC1(F)C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C28H18Cl2F2N2O4S/c29-23-12-11-21(15-24(23)30)39(37,38)33-25(35)13-10-19-6-3-7-22-26(19)34(27(36)28(22,31)32)16-17-8-9-18-4-1-2-5-20(18)14-17/h1-15H,16H2,(H,33,35)/b13-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315503 (CHEMBL1092871 | N-(3,4-dichlorophenylsulfonyl)-3-(...) Show SMILES Fc1ccc(CN2C(=O)Cc3cccc(\C=C\C(=O)NS(=O)(=O)c4ccc(Cl)c(Cl)c4)c23)cc1F Show InChI InChI=1S/C24H16Cl2F2N2O4S/c25-18-7-6-17(12-19(18)26)35(33,34)29-22(31)9-5-15-2-1-3-16-11-23(32)30(24(15)16)13-14-4-8-20(27)21(28)10-14/h1-10,12H,11,13H2,(H,29,31)/b9-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.300	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315521 (3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-...) Show SMILES CC1C(=O)N(Cc2ccc(Cl)cc2Cl)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(F)c(F)c1 Show InChI InChI=1S/C25H18Cl2F2N2O4S/c1-14-19-4-2-3-15(24(19)31(25(14)33)13-16-5-7-17(26)11-20(16)27)6-10-23(32)30-36(34,35)18-8-9-21(28)22(29)12-18/h2-12,14H,13H2,1H3,(H,30,32)/b10-6+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315529 (CHEMBL1089454 | N-(3-chlorophenylsulfonyl)-3-(3-me...) Show SMILES CC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C29H23ClN2O4S/c1-19-26-11-4-8-22(14-15-27(33)31-37(35,36)25-10-5-9-24(30)17-25)28(26)32(29(19)34)18-20-12-13-21-6-2-3-7-23(21)16-20/h2-17,19H,18H2,1H3,(H,31,33)/b15-14+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315499 (CHEMBL1088822 | N-(3,4-difluorophenylsulfonyl)-3-(...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)\C=C\c1cccc2CC(=O)N(Cc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C28H20F2N2O4S/c29-24-12-11-23(16-25(24)30)37(35,36)31-26(33)13-10-20-6-3-7-22-15-27(34)32(28(20)22)17-18-8-9-19-4-1-2-5-21(19)14-18/h1-14,16H,15,17H2,(H,31,33)/b13-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315504 (CHEMBL1088848 | N-(3-chlorophenylsulfonyl)-3-(1-(3...) Show SMILES Fc1ccc(CN2C(=O)Cc3cccc(\C=C\C(=O)NS(=O)(=O)c4cccc(Cl)c4)c23)cc1F Show InChI InChI=1S/C24H17ClF2N2O4S/c25-18-5-2-6-19(13-18)34(32,33)28-22(30)10-8-16-3-1-4-17-12-23(31)29(24(16)17)14-15-7-9-20(26)21(27)11-15/h1-11,13H,12,14H2,(H,28,30)/b10-8+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315506 (CHEMBL1091146 | N-(4,5-dichlorothiophen-2-ylsulfon...) Show SMILES Fc1ccc(CN2C(=O)Cc3cccc(\C=C\C(=O)NS(=O)(=O)c4cc(Cl)c(Cl)s4)c23)cc1F Show InChI InChI=1S/C22H14Cl2F2N2O4S2/c23-15-10-20(33-22(15)24)34(31,32)27-18(29)7-5-13-2-1-3-14-9-19(30)28(21(13)14)11-12-4-6-16(25)17(26)8-12/h1-8,10H,9,11H2,(H,27,29)/b7-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315492 (CHEMBL1092230 | N-(3-chlorophenylsulfonyl)-3-(1-(2...) Show SMILES Clc1ccc(CN2C(=O)Cc3cccc(\C=C\C(=O)NS(=O)(=O)c4cccc(Cl)c4)c23)c(Cl)c1 Show InChI InChI=1S/C24H17Cl3N2O4S/c25-18-5-2-6-20(12-18)34(32,33)28-22(30)10-8-15-3-1-4-16-11-23(31)29(24(15)16)14-17-7-9-19(26)13-21(17)27/h1-10,12-13H,11,14H2,(H,28,30)/b10-8+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315500 (CHEMBL1088823 | N-(3,4-dichlorophenylsulfonyl)-3-(...) Show SMILES Clc1ccc(cc1Cl)S(=O)(=O)NC(=O)\C=C\c1cccc2CC(=O)N(Cc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C28H20Cl2N2O4S/c29-24-12-11-23(16-25(24)30)37(35,36)31-26(33)13-10-20-6-3-7-22-15-27(34)32(28(20)22)17-18-8-9-19-4-1-2-5-21(19)14-18/h1-14,16H,15,17H2,(H,31,33)/b13-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315523 (CHEMBL1089161 | N-(3-chlorophenylsulfonyl)-3-(1-(2...) Show SMILES CC1C(=O)N(Cc2ccc(Cl)cc2Cl)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C25H19Cl3N2O4S/c1-15-21-7-2-4-16(9-11-23(31)29-35(33,34)20-6-3-5-18(26)12-20)24(21)30(25(15)32)14-17-8-10-19(27)13-22(17)28/h2-13,15H,14H2,1H3,(H,29,31)/b11-9+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315524 (3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-...) Show SMILES CC1C(=O)N(Cc2ccc(Cl)cc2Cl)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cc(F)c(F)cc1F Show InChI InChI=1S/C25H17Cl2F3N2O4S/c1-13-17-4-2-3-14(24(17)32(25(13)34)12-15-5-7-16(26)9-18(15)27)6-8-23(33)31-37(35,36)22-11-20(29)19(28)10-21(22)30/h2-11,13H,12H2,1H3,(H,31,33)/b8-6+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315530 (CHEMBL1089455 | N-(3,4-dichlorophenylsulfonyl)-3-(...) Show SMILES CC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C29H22Cl2N2O4S/c1-18-24-8-4-7-21(11-14-27(34)32-38(36,37)23-12-13-25(30)26(31)16-23)28(24)33(29(18)35)17-19-9-10-20-5-2-3-6-22(20)15-19/h2-16,18H,17H2,1H3,(H,32,34)/b14-11+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315527 (CHEMBL1090459 | N-(3,4-difluorophenylsulfonyl)-3-(...) Show SMILES CC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(F)c(F)c1 Show InChI InChI=1S/C29H22F2N2O4S/c1-18-24-8-4-7-21(11-14-27(34)32-38(36,37)23-12-13-25(30)26(31)16-23)28(24)33(29(18)35)17-19-9-10-20-5-2-3-6-22(20)15-19/h2-16,18H,17H2,1H3,(H,32,34)/b14-11+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315469 (3-(3-hydroxy-1-(naphthalen-2-ylmethyl)-2-oxoindoli...) Show SMILES OC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cc(F)c(F)cc1F Show InChI InChI=1S/C28H19F3N2O5S/c29-21-13-23(31)24(14-22(21)30)39(37,38)32-25(34)11-10-18-6-3-7-20-26(18)33(28(36)27(20)35)15-16-8-9-17-4-1-2-5-19(17)12-16/h1-14,27,35H,15H2,(H,32,34)/b11-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315518 (3-(1-(naphthalen-2-ylmethyl)-2,3-dioxoindolin-7-yl...) Show SMILES Fc1cc(F)c(cc1F)S(=O)(=O)NC(=O)\C=C\c1cccc2C(=O)C(=O)N(Cc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C28H17F3N2O5S/c29-21-13-23(31)24(14-22(21)30)39(37,38)32-25(34)11-10-18-6-3-7-20-26(18)33(28(36)27(20)35)15-16-8-9-17-4-1-2-5-19(17)12-16/h1-14H,15H2,(H,32,34)/b11-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315501 (CHEMBL1088846 | N-(3-chlorophenylsulfonyl)-3-(1-(n...) Show SMILES Clc1cccc(c1)S(=O)(=O)NC(=O)\C=C\c1cccc2CC(=O)N(Cc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C28H21ClN2O4S/c29-24-9-4-10-25(17-24)36(34,35)30-26(32)14-13-21-7-3-8-23-16-27(33)31(28(21)23)18-19-11-12-20-5-1-2-6-22(20)15-19/h1-15,17H,16,18H2,(H,30,32)/b14-13+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315494 (3-(1-(2,4-dichlorobenzyl)-2-oxoindolin-7-yl)-N-(3,...) Show SMILES Fc1ccc(cc1F)S(=O)(=O)NC(=O)\C=C\c1cccc2CC(=O)N(Cc3ccc(Cl)cc3Cl)c12 Show InChI InChI=1S/C24H16Cl2F2N2O4S/c25-17-6-4-16(19(26)11-17)13-30-23(32)10-15-3-1-2-14(24(15)30)5-9-22(31)29-35(33,34)18-7-8-20(27)21(28)12-18/h1-9,11-12H,10,13H2,(H,29,31)/b9-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315505 (3-(1-(3,4-difluorobenzyl)-2-oxoindolin-7-yl)-N-(2,...) Show SMILES Fc1ccc(CN2C(=O)Cc3cccc(\C=C\C(=O)NS(=O)(=O)c4cc(F)c(F)cc4F)c23)cc1F Show InChI InChI=1S/C24H15F5N2O4S/c25-16-6-4-13(8-17(16)26)12-31-23(33)9-15-3-1-2-14(24(15)31)5-7-22(32)30-36(34,35)21-11-19(28)18(27)10-20(21)29/h1-8,10-11H,9,12H2,(H,30,32)/b7-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.700	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315531 (CHEMBL1093124 | N-(3,4-dichlorophenylsulfonyl)-3-(...) Show SMILES CC1C(=O)N(Cc2ccc(F)c(F)c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C25H18Cl2F2N2O4S/c1-14-18-4-2-3-16(24(18)31(25(14)33)13-15-5-9-21(28)22(29)11-15)6-10-23(32)30-36(34,35)17-7-8-19(26)20(27)12-17/h2-12,14H,13H2,1H3,(H,30,32)/b10-6+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315502 (3-(1-(3,4-difluorobenzyl)-2-oxoindolin-7-yl)-N-(3,...) Show SMILES Fc1ccc(CN2C(=O)Cc3cccc(\C=C\C(=O)NS(=O)(=O)c4ccc(F)c(F)c4)c23)cc1F Show InChI InChI=1S/C24H16F4N2O4S/c25-18-7-4-14(10-20(18)27)13-30-23(32)11-16-3-1-2-15(24(16)30)5-9-22(31)29-35(33,34)17-6-8-19(26)21(28)12-17/h1-10,12H,11,13H2,(H,29,31)/b9-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315522 (3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-...) Show SMILES CC1C(=O)N(Cc2ccc(Cl)cc2Cl)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(Cl)c(Cl)c1 Show InChI InChI=1S/C25H18Cl4N2O4S/c1-14-19-4-2-3-15(24(19)31(25(14)33)13-16-5-7-17(26)11-21(16)28)6-10-23(32)30-36(34,35)18-8-9-20(27)22(29)12-18/h2-12,14H,13H2,1H3,(H,30,32)/b10-6+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315467 (CHEMBL1093791 | N-(4-fluorophenylsulfonyl)-3-(3-hy...) Show SMILES OC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(F)cc1 Show InChI InChI=1S/C28H21FN2O5S/c29-22-11-13-23(14-12-22)37(35,36)30-25(32)15-10-20-6-3-7-24-26(20)31(28(34)27(24)33)17-18-8-9-19-4-1-2-5-21(19)16-18/h1-16,27,33H,17H2,(H,30,32)/b15-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315517 (CHEMBL1093133 | N-(3,4-dichlorophenylsulfonyl)-3-(...) Show SMILES Clc1ccc(cc1Cl)S(=O)(=O)NC(=O)\C=C\c1cccc2C(=O)C(=O)N(Cc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C28H18Cl2N2O5S/c29-23-12-11-21(15-24(23)30)38(36,37)31-25(33)13-10-19-6-3-7-22-26(19)32(28(35)27(22)34)16-17-8-9-18-4-1-2-5-20(18)14-17/h1-15H,16H2,(H,31,33)/b13-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315475 (CHEMBL1091606 | N-(4-chlorophenylsulfonyl)-3-(1-(2...) Show SMILES FC1(F)C(=O)N(Cc2ccc(Cl)cc2Cl)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(Cl)cc1 Show InChI InChI=1S/C24H15Cl3F2N2O4S/c25-16-7-9-18(10-8-16)36(34,35)30-21(32)11-5-14-2-1-3-19-22(14)31(23(33)24(19,28)29)13-15-4-6-17(26)12-20(15)27/h1-12H,13H2,(H,30,32)/b11-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315495 (3-(1-(2,4-dichlorobenzyl)-2-oxoindolin-7-yl)-N-(3,...) Show SMILES Clc1ccc(CN2C(=O)Cc3cccc(\C=C\C(=O)NS(=O)(=O)c4ccc(Cl)c(Cl)c4)c23)c(Cl)c1 Show InChI InChI=1S/C24H16Cl4N2O4S/c25-17-6-4-16(20(27)11-17)13-30-23(32)10-15-3-1-2-14(24(15)30)5-9-22(31)29-35(33,34)18-7-8-19(26)21(28)12-18/h1-9,11-12H,10,13H2,(H,29,31)/b9-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315488 (CHEMBL1091622 | N-(3,4-dichlorophenylsulfonyl)-3-(...) Show SMILES Fc1ccc(CN2C(=O)C(F)(F)c3cccc(\C=C\C(=O)NS(=O)(=O)c4ccc(Cl)c(Cl)c4)c23)cc1F Show InChI InChI=1S/C24H14Cl2F4N2O4S/c25-17-7-6-15(11-18(17)26)37(35,36)31-21(33)9-5-14-2-1-3-16-22(14)32(23(34)24(16,29)30)12-13-4-8-19(27)20(28)10-13/h1-11H,12H2,(H,31,33)/b9-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315487 (3-(1-(3,4-difluorobenzyl)-3,3-difluoro-2-oxoindoli...) Show SMILES Fc1ccc(CN2C(=O)C(F)(F)c3cccc(\C=C\C(=O)NS(=O)(=O)c4ccc(F)c(F)c4)c23)cc1F Show InChI InChI=1S/C24H14F6N2O4S/c25-17-7-4-13(10-19(17)27)12-32-22-14(2-1-3-16(22)24(29,30)23(32)34)5-9-21(33)31-37(35,36)15-6-8-18(26)20(28)11-15/h1-11H,12H2,(H,31,33)/b9-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315496 (CHEMBL1088785 | N-(4,5-dichlorothiophen-2-ylsulfon...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)\C=C\c1cccc2CC(=O)N(Cc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C26H18Cl2N2O4S2/c27-21-14-24(35-26(21)28)36(33,34)29-22(31)11-10-18-6-3-7-20-13-23(32)30(25(18)20)15-16-8-9-17-4-1-2-5-19(17)12-16/h1-12,14H,13,15H2,(H,29,31)/b11-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315532 (3-(1-(3,4-difluorobenzyl)-3-methyl-2-oxoindolin-7-...) Show SMILES CC1C(=O)N(Cc2ccc(F)c(F)c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cc(F)c(F)cc1F Show InChI InChI=1S/C25H17F5N2O4S/c1-13-16-4-2-3-15(24(16)32(25(13)34)12-14-5-7-17(26)18(27)9-14)6-8-23(33)31-37(35,36)22-11-20(29)19(28)10-21(22)30/h2-11,13H,12H2,1H3,(H,31,33)/b8-6+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315516 (CHEMBL1090455 | N-(4-fluorophenylsulfonyl)-3-(1-(n...) Show SMILES Fc1ccc(cc1)S(=O)(=O)NC(=O)\C=C\c1cccc2C(=O)C(=O)N(Cc3ccc4ccccc4c3)c12 Show InChI InChI=1S/C28H19FN2O5S/c29-22-11-13-23(14-12-22)37(35,36)30-25(32)15-10-20-6-3-7-24-26(20)31(28(34)27(24)33)17-18-8-9-19-4-1-2-5-21(19)16-18/h1-16H,17H2,(H,30,32)/b15-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315468 (CHEMBL1093792 | N-(3,4-difluorophenylsulfonyl)-3-(...) Show SMILES OC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(F)c(F)c1 Show InChI InChI=1S/C28H20F2N2O5S/c29-23-12-11-21(15-24(23)30)38(36,37)31-25(33)13-10-19-6-3-7-22-26(19)32(28(35)27(22)34)16-17-8-9-18-4-1-2-5-20(18)14-17/h1-15,27,34H,16H2,(H,31,33)/b13-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315482 (CHEMBL1093897 | N-(3-chlorophenylsulfonyl)-3-(3,3-...) Show SMILES FC1(F)C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C28H19ClF2N2O4S/c29-22-8-4-9-23(16-22)38(36,37)32-25(34)14-13-20-7-3-10-24-26(20)33(27(35)28(24,30)31)17-18-11-12-19-5-1-2-6-21(19)15-18/h1-16H,17H2,(H,32,34)/b14-13+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315507 (3-(3,3-bis(hydroxymethyl)-1-(naphthalen-2-ylmethyl...) Show SMILES OCC1(CO)C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cc(Cl)c(Cl)s1 Show InChI InChI=1S/C28H22Cl2N2O6S2/c29-22-13-24(39-26(22)30)40(37,38)31-23(35)11-10-19-6-3-7-21-25(19)32(27(36)28(21,15-33)16-34)14-17-8-9-18-4-1-2-5-20(18)12-17/h1-13,33-34H,14-16H2,(H,31,35)/b11-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315519 (3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-...) Show SMILES CC1C(=O)N(Cc2ccc(Cl)cc2Cl)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cccs1 Show InChI InChI=1S/C23H18Cl2N2O4S2/c1-14-18-5-2-4-15(8-10-20(28)26-33(30,31)21-6-3-11-32-21)22(18)27(23(14)29)13-16-7-9-17(24)12-19(16)25/h2-12,14H,13H2,1H3,(H,26,28)/b10-8+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315483 (3-(3,3-difluoro-1-(naphthalen-2-ylmethyl)-2-oxoind...) Show SMILES Fc1ccc(cc1)S(=O)(=O)NC(=O)\C=C\c1cccc2c1N(Cc1ccc3ccccc3c1)C(=O)C2(F)F Show InChI InChI=1S/C28H19F3N2O4S/c29-22-11-13-23(14-12-22)38(36,37)32-25(34)15-10-20-6-3-7-24-26(20)33(27(35)28(24,30)31)17-18-8-9-19-4-1-2-5-21(19)16-18/h1-16H,17H2,(H,32,34)/b15-10+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315529 (CHEMBL1089454 | N-(3-chlorophenylsulfonyl)-3-(3-me...) Show SMILES CC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cccc(Cl)c1 Show InChI InChI=1S/C29H23ClN2O4S/c1-19-26-11-4-8-22(14-15-27(33)31-37(35,36)25-10-5-9-24(30)17-25)28(26)32(29(19)34)18-20-12-13-21-6-2-3-7-23(21)16-20/h2-17,19H,18H2,1H3,(H,31,33)/b15-14+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315490 (3-(1-(2,4-dichlorobenzyl)-2-oxoindolin-7-yl)-N-(4,...) Show SMILES Clc1cc(sc1Cl)S(=O)(=O)NC(=O)\C=C\c1cccc2CC(=O)N(Cc3ccc(Cl)cc3Cl)c12 Show InChI InChI=1S/C22H14Cl4N2O4S2/c23-15-6-4-14(16(24)9-15)11-28-19(30)8-13-3-1-2-12(21(13)28)5-7-18(29)27-34(31,32)20-10-17(25)22(26)33-20/h1-7,9-10H,8,11H2,(H,27,29)/b7-5+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in buffer				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315526 (CHEMBL1090458 | N-(4,5-dichlorothiophen-2-ylsulfon...) Show SMILES CC1C(=O)N(Cc2ccc3ccccc3c2)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1cc(Cl)c(Cl)s1 Show InChI InChI=1S/C27H20Cl2N2O4S2/c1-16-21-8-4-7-19(11-12-23(32)30-37(34,35)24-14-22(28)26(29)36-24)25(21)31(27(16)33)15-17-9-10-18-5-2-3-6-20(18)13-17/h2-14,16H,15H2,1H3,(H,30,32)/b12-11+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair
Prostaglandin E2 receptor EP3 subtype (Homo sapiens (Human))	BDBM50315521 (3-(1-(2,4-dichlorobenzyl)-3-methyl-2-oxoindolin-7-...) Show SMILES CC1C(=O)N(Cc2ccc(Cl)cc2Cl)c2c1cccc2\C=C\C(=O)NS(=O)(=O)c1ccc(F)c(F)c1 Show InChI InChI=1S/C25H18Cl2F2N2O4S/c1-14-19-4-2-3-15(24(19)31(25(14)33)13-16-5-7-17(26)11-20(16)27)6-10-23(32)30-36(34,35)18-8-9-21(28)22(29)12-18/h2-12,14H,13H2,1H3,(H,30,32)/b10-6+	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
deCODE Chemistry Curated by ChEMBL					Assay Description Displacement of [3H]PGE2 from human EP3 receptor in presence of 10% human serum				Bioorg Med Chem Lett 20: 2658-64 (2010) Article DOI: 10.1016/j.bmcl.2010.02.028 BindingDB Entry DOI: 10.7270/Q2668DCG
					More data for this Ligand-Target Pair

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