BindingDB PrimarySearch

Found 19 hits Enz. Inhib. hit(s) with all data for entry = 50031647
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Arginase-1 (Homo sapiens (Human))	BDBM50316603 (2-(S)-amino-5-(2-aminoimidazol-1-yl)pentanoic acid...) Show SMILES N[C@@H](CCCn1ccnc1N)C(O)=O \|r\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assay				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50316607 (2-amino-L-histidine \| CHEMBL1099167 \| L-2-aminohis...) Show SMILES N[C@@H](Cc1cnc(N)[nH]1)C(O)=O \|r\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	MMDB PDB Article PubMed	3.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assay				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Arginase-1 (Homo sapiens (Human))	BDBM50316604 ((S)-2-amino-5-(imidazol-2-ylamino)pentanoic acid \|...) Show SMILES N[C@@H](CCCNc1ncc[nH]1)C(O)=O \|r\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	5.00E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assay				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50316606 ((2S)-2-amino-4-(2-amino-1H-imidazol-5-yl)butanoic ...) Show SMILES N[C@@H](CCc1cnc(N)[nH]1)C(O)=O \|r\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	MMDB PDB Article PubMed	3.00E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assay				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (crystal)
Arginase-1 (Homo sapiens (Human))	BDBM50316608 (1H-Imidazol-2-yl-ammonium \| 1H-Imidazol-2-ylamine ...) Show SMILES Nc1ncc[nH]1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	MMDB Article PubMed	3.60E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assay				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50316605 (2-amino-5-(2-aminoimidazol-4-yl)pentanoic acid \| C...) Show SMILES NC(CCCc1cnc(N)[nH]1)C(O)=O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	>8.00E+7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by fixed point assay				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM50316607 (2-amino-L-histidine \| CHEMBL1099167 \| L-2-aminohis...) Show SMILES N[C@@H](Cc1cnc(N)[nH]1)C(O)=O \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition rat recombinant nNOS				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50316604 ((S)-2-amino-5-(imidazol-2-ylamino)pentanoic acid \|...) Show SMILES N[C@@H](CCCNc1ncc[nH]1)C(O)=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of mouse recombinant iNOS				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM50316604 ((S)-2-amino-5-(imidazol-2-ylamino)pentanoic acid \|...) Show SMILES N[C@@H](CCCNc1ncc[nH]1)C(O)=O \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition rat recombinant nNOS				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM50316608 (1H-Imidazol-2-yl-ammonium \| 1H-Imidazol-2-ylamine ...) Show SMILES Nc1ncc[nH]1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition rat recombinant nNOS				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50316608 (1H-Imidazol-2-yl-ammonium \| 1H-Imidazol-2-ylamine ...) Show SMILES Nc1ncc[nH]1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid PDB UniChem Patents	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of mouse recombinant iNOS				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50316607 (2-amino-L-histidine \| CHEMBL1099167 \| L-2-aminohis...) Show SMILES N[C@@H](Cc1cnc(N)[nH]1)C(O)=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of mouse recombinant iNOS				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM50316606 ((2S)-2-amino-4-(2-amino-1H-imidazol-5-yl)butanoic ...) Show SMILES N[C@@H](CCc1cnc(N)[nH]1)C(O)=O \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition rat recombinant nNOS				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50316606 ((2S)-2-amino-4-(2-amino-1H-imidazol-5-yl)butanoic ...) Show SMILES N[C@@H](CCc1cnc(N)[nH]1)C(O)=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of mouse recombinant iNOS				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM50316605 (2-amino-5-(2-aminoimidazol-4-yl)pentanoic acid \| C...) Show SMILES NC(CCCc1cnc(N)[nH]1)C(O)=O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition rat recombinant nNOS				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50316605 (2-amino-5-(2-aminoimidazol-4-yl)pentanoic acid \| C...) Show SMILES NC(CCCc1cnc(N)[nH]1)C(O)=O Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of mouse recombinant iNOS				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, brain (Rattus norvegicus (rat))	BDBM50316603 (2-(S)-amino-5-(2-aminoimidazol-1-yl)pentanoic acid...) Show SMILES N[C@@H](CCCn1ccnc1N)C(O)=O \|r\| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition rat recombinant nNOS				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Nitric oxide synthase, inducible (Mus musculus (mouse))	BDBM50316603 (2-(S)-amino-5-(2-aminoimidazol-1-yl)pentanoic acid...) Show SMILES N[C@@H](CCCn1ccnc1N)C(O)=O \|r\| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.35E+5	n/a	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of mouse recombinant iNOS				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair
Arginase-1 (Homo sapiens (Human))	BDBM50316603 (2-(S)-amino-5-(2-aminoimidazol-1-yl)pentanoic acid...) Show SMILES N[C@@H](CCCn1ccnc1N)C(O)=O \|r\| Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a
University of Pennsylvania Curated by ChEMBL					Assay Description Inhibition of human recombinant full length arginase 1 expressed in Escherichia coli BL21(DE3) by surface plasmon resonance assay				J Med Chem 53: 4266-76 (2010) Article DOI: 10.1021/jm100306a BindingDB Entry DOI: 10.7270/Q2SQ90JK
University of Pennsylvania Curated by ChEMBL					More data for this Ligand-Target Pair