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Compile Data Set for Download or QSAR

Found 123 hits Enz. Inhib. hit(s) with all data for entry = 50048487   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217990
PNG
(CHEMBL54560)
Show SMILES CSc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4C)nc3)c2cc1C(F)(F)F
Show InChI InChI=1S/C22H19F3N4O2S/c1-13-18(4-3-8-26-13)31-20-6-5-15(12-27-20)28-21(30)29-9-7-14-10-19(32-2)16(11-17(14)29)22(23,24)25/h3-6,8,10-12H,7,9H2,1-2H3,(H,28,30)
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 0.398n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217974
PNG
(CHEMBL55207)
Show SMILES Cc1cc2CCN(C(=O)Nc3ccc(Oc4cnccc4Cl)nc3)c2cc1Cl
Show InChI InChI=1S/C20H16Cl2N4O2/c1-12-8-13-5-7-26(17(13)9-16(12)22)20(27)25-14-2-3-19(24-10-14)28-18-11-23-6-4-15(18)21/h2-4,6,8-11H,5,7H2,1H3,(H,25,27)
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 0.501n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217991
PNG
(CHEMBL301012)
Show SMILES Cc1cc2CCN(C(=O)Nc3cnc(Oc4cccnc4C)c(Cl)c3)c2cc1Cl
Show InChI InChI=1S/C21H18Cl2N4O2/c1-12-8-14-5-7-27(18(14)10-16(12)22)21(28)26-15-9-17(23)20(25-11-15)29-19-4-3-6-24-13(19)2/h3-4,6,8-11H,5,7H2,1-2H3,(H,26,28)
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 0.631n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50086071
PNG
(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)
Show SMILES COc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4C)nc3)c2cc1C(F)(F)F
Show InChI InChI=1S/C22H19F3N4O3/c1-13-18(4-3-8-26-13)32-20-6-5-15(12-27-20)28-21(30)29-9-7-14-10-19(31-2)16(11-17(14)29)22(23,24)25/h3-6,8,10-12H,7,9H2,1-2H3,(H,28,30)
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 0.631n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217980
PNG
(CHEMBL59584)
Show SMILES Cc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4C)nc3)c2cc1Br
Show InChI InChI=1S/C21H19BrN4O2/c1-13-10-15-7-9-26(18(15)11-17(13)22)21(27)25-16-5-6-20(24-12-16)28-19-4-3-8-23-14(19)2/h3-6,8,10-12H,7,9H2,1-2H3,(H,25,27)
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 0.794n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50086065
PNG
(5-Methyl-6-trifluoromethyl-2,3-dihydro-indole-1-ca...)
Show SMILES Cc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4C)nc3)c2cc1C(F)(F)F
Show InChI InChI=1S/C22H19F3N4O2/c1-13-10-15-7-9-29(18(15)11-17(13)22(23,24)25)21(30)28-16-5-6-20(27-12-16)31-19-4-3-8-26-14(19)2/h3-6,8,10-12H,7,9H2,1-2H3,(H,28,30)
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 1n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM85097
PNG
(CAS_181632-25-7 | CHEMBL14563 | SB 242084)
Show SMILES Cc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4C)nc3)c2cc1Cl
Show InChI InChI=1S/C21H19ClN4O2/c1-13-10-15-7-9-26(18(15)11-17(13)22)21(27)25-16-5-6-20(24-12-16)28-19-4-3-8-23-14(19)2/h3-6,8,10-12H,7,9H2,1-2H3,(H,25,27)
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 1n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217977
PNG
(CHEMBL55331)
Show SMILES Cc1ccncc1Oc1ccc(NC(=O)N2CCc3cc(C)c(Cl)cc23)cn1
Show InChI InChI=1S/C21H19ClN4O2/c1-13-5-7-23-12-19(13)28-20-4-3-16(11-24-20)25-21(27)26-8-6-15-9-14(2)17(22)10-18(15)26/h3-5,7,9-12H,6,8H2,1-2H3,(H,25,27)
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 1n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217972
PNG
(CHEMBL55079)
Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3c2cc(Cl)c(C)c3Cl)cn1
Show InChI InChI=1S/C21H18Cl2N4O2/c1-12-16(22)10-17-15(20(12)23)7-9-27(17)21(28)26-14-5-6-19(25-11-14)29-18-4-3-8-24-13(18)2/h3-6,8,10-11H,7,9H2,1-2H3,(H,26,28)
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 1n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217993
PNG
(CHEMBL55292)
Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3c4CCOc4c(cc23)C(F)(F)F)cn1
Show InChI InChI=1S/C23H19F3N4O3/c1-13-19(3-2-8-27-13)33-20-5-4-14(12-28-20)29-22(31)30-9-6-15-16-7-10-32-21(16)17(11-18(15)30)23(24,25)26/h2-5,8,11-12H,6-7,9-10H2,1H3,(H,29,31)
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 1.30n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217986
PNG
(CHEMBL294030)
Show SMILES Cc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4Cl)nc3)c2cc1Cl
Show InChI InChI=1S/C20H16Cl2N4O2/c1-12-9-13-6-8-26(16(13)10-15(12)21)20(27)25-14-4-5-18(24-11-14)28-17-3-2-7-23-19(17)22/h2-5,7,9-11H,6,8H2,1H3,(H,25,27)
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 1.30n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217970
PNG
(CHEMBL292228)
Show SMILES Cc1cc2N(CCc2cc1Cl)C(=O)Nc1ccc(Oc2cccnc2C)nc1
Show InChI InChI=1S/C21H19ClN4O2/c1-13-10-18-15(11-17(13)22)7-9-26(18)21(27)25-16-5-6-20(24-12-16)28-19-4-3-8-23-14(19)2/h3-6,8,10-12H,7,9H2,1-2H3,(H,25,27)
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 1.30n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217978
PNG
(CHEMBL53152)
Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3cc(Br)c(cc23)C(F)(F)F)cn1
Show InChI InChI=1S/C21H16BrF3N4O2/c1-12-18(3-2-7-26-12)31-19-5-4-14(11-27-19)28-20(30)29-8-6-13-9-16(22)15(10-17(13)29)21(23,24)25/h2-5,7,9-11H,6,8H2,1H3,(H,28,30)
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 1.30n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217966
PNG
(CHEMBL54775)
Show SMILES Cc1ccc2N(CCc2c1Br)C(=O)Nc1ccc(Oc2cccnc2C)nc1
Show InChI InChI=1S/C21H19BrN4O2/c1-13-5-7-17-16(20(13)22)9-11-26(17)21(27)25-15-6-8-19(24-12-15)28-18-4-3-10-23-14(18)2/h3-8,10,12H,9,11H2,1-2H3,(H,25,27)
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 1.60n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217981
PNG
(CHEMBL55964)
Show SMILES Cc1cc2CCN(C(=O)Nc3cnc(Oc4cccnc4C)c(C)c3)c2cc1Cl
Show InChI InChI=1S/C22H21ClN4O2/c1-13-9-16-6-8-27(19(16)11-18(13)23)22(28)26-17-10-14(2)21(25-12-17)29-20-5-4-7-24-15(20)3/h4-5,7,9-12H,6,8H2,1-3H3,(H,26,28)
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 1.60n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217989
PNG
(CHEMBL56508)
Show SMILES Cc1cc2CCN(C(=O)Nc3cnc(Oc4cccnc4C)c(Cl)c3)c2cc1C(F)(F)F
Show InChI InChI=1S/C22H18ClF3N4O2/c1-12-8-14-5-7-30(18(14)10-16(12)22(24,25)26)21(31)29-15-9-17(23)20(28-11-15)32-19-4-3-6-27-13(19)2/h3-4,6,8-11H,5,7H2,1-2H3,(H,29,31)
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 1.60n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217982
PNG
(CHEMBL56336)
Show SMILES Cc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4C)nc3)c2cc1F
Show InChI InChI=1S/C21H19FN4O2/c1-13-10-15-7-9-26(18(15)11-17(13)22)21(27)25-16-5-6-20(24-12-16)28-19-4-3-8-23-14(19)2/h3-6,8,10-12H,7,9H2,1-2H3,(H,25,27)
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 1.60n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217968
PNG
(CHEMBL55472)
Show SMILES CCCc1ncccc1Oc1ccc(NC(=O)N2CCc3cc(C)c(Cl)cc23)cn1
Show InChI InChI=1S/C23H23ClN4O2/c1-3-5-19-21(6-4-10-25-19)30-22-8-7-17(14-26-22)27-23(29)28-11-9-16-12-15(2)18(24)13-20(16)28/h4,6-8,10,12-14H,3,5,9,11H2,1-2H3,(H,27,29)
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 1.60n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217985
PNG
(CHEMBL52308)
Show SMILES Cc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4C)nn3)c2cc1Cl
Show InChI InChI=1S/C20H18ClN5O2/c1-12-10-14-7-9-26(16(14)11-15(12)21)20(27)23-18-5-6-19(25-24-18)28-17-4-3-8-22-13(17)2/h3-6,8,10-11H,7,9H2,1-2H3,(H,23,24,27)
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 2n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217984
PNG
(CHEMBL53308)
Show SMILES Cc1cc2CCN(C(=O)Nc3cnc(Oc4cccnc4C)cn3)c2cc1C(F)(F)F
Show InChI InChI=1S/C21H18F3N5O2/c1-12-8-14-5-7-29(16(14)9-15(12)21(22,23)24)20(30)28-18-10-27-19(11-26-18)31-17-4-3-6-25-13(17)2/h3-4,6,8-11H,5,7H2,1-2H3,(H,26,28,30)
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 2n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50321890
PNG
(5,6-Dichloro-2,3-dihydro-indole-1-carboxylic acid ...)
Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3cc(Cl)c(Cl)cc23)cn1
Show InChI InChI=1S/C20H16Cl2N4O2/c1-12-18(3-2-7-23-12)28-19-5-4-14(11-24-19)25-20(27)26-8-6-13-9-15(21)16(22)10-17(13)26/h2-5,7,9-11H,6,8H2,1H3,(H,25,27)
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 2n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217988
PNG
(CHEMBL55792)
Show SMILES CCc1ncccc1Oc1ccc(NC(=O)N2CCc3cc(C)c(Cl)cc23)cn1
Show InChI InChI=1S/C22H21ClN4O2/c1-3-18-20(5-4-9-24-18)29-21-7-6-16(13-25-21)26-22(28)27-10-8-15-11-14(2)17(23)12-19(15)27/h4-7,9,11-13H,3,8,10H2,1-2H3,(H,26,28)
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 2n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217975
PNG
(CHEMBL299938)
Show SMILES Cc1cc2CCN(C(=O)Nc3ccc(Oc4cncnc4C)nc3)c2cc1C(F)(F)F
Show InChI InChI=1S/C21H18F3N5O2/c1-12-7-14-5-6-29(17(14)8-16(12)21(22,23)24)20(30)28-15-3-4-19(26-9-15)31-18-10-25-11-27-13(18)2/h3-4,7-11H,5-6H2,1-2H3,(H,28,30)
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 2n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217973
PNG
(CHEMBL52919)
Show SMILES CCc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4C)nc3)c2cc1C(F)(F)F
Show InChI InChI=1S/C23H21F3N4O2/c1-3-15-11-16-8-10-30(19(16)12-18(15)23(24,25)26)22(31)29-17-6-7-21(28-13-17)32-20-5-4-9-27-14(20)2/h4-7,9,11-13H,3,8,10H2,1-2H3,(H,29,31)
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 2.5n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50321861
PNG
(5-Iodo-2,3-dihydro-indole-1-carboxylic acid [6-(2-...)
Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3cc(I)ccc23)cn1
Show InChI InChI=1S/C20H17IN4O2/c1-13-18(3-2-9-22-13)27-19-7-5-16(12-23-19)24-20(26)25-10-8-14-11-15(21)4-6-17(14)25/h2-7,9,11-12H,8,10H2,1H3,(H,24,26)
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 3.20n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50321862
PNG
(5-Bromo-2,3-dihydro-indole-1-carboxylic acid [6-(2...)
Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3cc(Br)ccc23)cn1
Show InChI InChI=1S/C20H17BrN4O2/c1-13-18(3-2-9-22-13)27-19-7-5-16(12-23-19)24-20(26)25-10-8-14-11-15(21)4-6-17(14)25/h2-7,9,11-12H,8,10H2,1H3,(H,24,26)
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 3.20n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217994
PNG
(CHEMBL58765)
Show SMILES Cc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4C)nn3)c2cc1C(F)(F)F
Show InChI InChI=1S/C21H18F3N5O2/c1-12-10-14-7-9-29(16(14)11-15(12)21(22,23)24)20(30)26-18-5-6-19(28-27-18)31-17-4-3-8-25-13(17)2/h3-6,8,10-11H,7,9H2,1-2H3,(H,26,27,30)
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 3.20n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217992
PNG
(CHEMBL56050)
Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3c2ccc(Cl)c3Cl)cn1
Show InChI InChI=1S/C20H16Cl2N4O2/c1-12-17(3-2-9-23-12)28-18-7-4-13(11-24-18)25-20(27)26-10-8-14-16(26)6-5-15(21)19(14)22/h2-7,9,11H,8,10H2,1H3,(H,25,27)
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 3.20n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217983
PNG
(CHEMBL53113)
Show SMILES Cc1cc2CCN(C(=O)Nc3cnc(Oc4cccnc4C)nc3)c2cc1Cl
Show InChI InChI=1S/C20H18ClN5O2/c1-12-8-14-5-7-26(17(14)9-16(12)21)20(27)25-15-10-23-19(24-11-15)28-18-4-3-6-22-13(18)2/h3-4,6,8-11H,5,7H2,1-2H3,(H,25,27)
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 3.20n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217967
PNG
(CHEMBL54610)
Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3cc(ccc23)C(F)(F)F)cn1
Show InChI InChI=1S/C21H17F3N4O2/c1-13-18(3-2-9-25-13)30-19-7-5-16(12-26-19)27-20(29)28-10-8-14-11-15(21(22,23)24)4-6-17(14)28/h2-7,9,11-12H,8,10H2,1H3,(H,27,29)
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 4n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50321891
PNG
(6-Chloro-2,3-dihydro-indole-1-carboxylic acid [6-(...)
Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3ccc(Cl)cc23)cn1
Show InChI InChI=1S/C20H17ClN4O2/c1-13-18(3-2-9-22-13)27-19-7-6-16(12-23-19)24-20(26)25-10-8-14-4-5-15(21)11-17(14)25/h2-7,9,11-12H,8,10H2,1H3,(H,24,26)
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 4n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217976
PNG
(CHEMBL291510)
Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3ccc(cc23)C(F)(F)F)cn1
Show InChI InChI=1S/C21H17F3N4O2/c1-13-18(3-2-9-25-13)30-19-7-6-16(12-26-19)27-20(29)28-10-8-14-4-5-15(11-17(14)28)21(22,23)24/h2-7,9,11-12H,8,10H2,1H3,(H,27,29)
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 5n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50321889
PNG
(6-Chloro-5-fluoro-2,3-dihydro-indole-1-carboxylic ...)
Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3cc(F)c(Cl)cc23)cn1
Show InChI InChI=1S/C20H16ClFN4O2/c1-12-18(3-2-7-23-12)28-19-5-4-14(11-24-19)25-20(27)26-8-6-13-9-16(22)15(21)10-17(13)26/h2-5,7,9-11H,6,8H2,1H3,(H,25,27)
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 6.30n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50321863
PNG
(5-Chloro-2,3-dihydro-indole-1-carboxylic acid [6-(...)
Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3cc(Cl)ccc23)cn1
Show InChI InChI=1S/C20H17ClN4O2/c1-13-18(3-2-9-22-13)27-19-7-5-16(12-23-19)24-20(26)25-10-8-14-11-15(21)4-6-17(14)25/h2-7,9,11-12H,8,10H2,1H3,(H,24,26)
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 6.30n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50217977
PNG
(CHEMBL55331)
Show SMILES Cc1ccncc1Oc1ccc(NC(=O)N2CCc3cc(C)c(Cl)cc23)cn1
Show InChI InChI=1S/C21H19ClN4O2/c1-13-5-7-23-12-19(13)28-20-4-3-16(11-24-20)25-21(27)26-8-6-15-9-14(2)17(22)10-18(15)26/h3-5,7,9-12H,6,8H2,1-2H3,(H,25,27)
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 7.90n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2A receptor of HEK293 cells by displacement of [3H]ketanserin

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50217975
PNG
(CHEMBL299938)
Show SMILES Cc1cc2CCN(C(=O)Nc3ccc(Oc4cncnc4C)nc3)c2cc1C(F)(F)F
Show InChI InChI=1S/C21H18F3N5O2/c1-12-7-14-5-6-29(17(14)8-16(12)21(22,23)24)20(30)28-15-3-4-19(26-9-15)31-18-10-25-11-27-13(18)2/h3-4,7-11H,5-6H2,1-2H3,(H,28,30)
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 13n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-HT2B receptor of HEK293 cells by displacement of [3H]5-HT

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50217974
PNG
(CHEMBL55207)
Show SMILES Cc1cc2CCN(C(=O)Nc3ccc(Oc4cnccc4Cl)nc3)c2cc1Cl
Show InChI InChI=1S/C20H16Cl2N4O2/c1-12-8-13-5-7-26(17(13)9-16(12)22)20(27)25-14-2-3-19(24-10-14)28-18-11-23-6-4-15(18)21/h2-4,6,8-11H,5,7H2,1H3,(H,25,27)
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 13n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-HT2B receptor of HEK293 cells by displacement of [3H]5-HT

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217969
PNG
(CHEMBL298696)
Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3c2cccc3Cl)cn1
Show InChI InChI=1S/C20H17ClN4O2/c1-13-18(6-3-10-22-13)27-19-8-7-14(12-23-19)24-20(26)25-11-9-15-16(21)4-2-5-17(15)25/h2-8,10,12H,9,11H2,1H3,(H,24,26)
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 16n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2A


(Homo sapiens (Human))		BDBM50217974
PNG
(CHEMBL55207)
Show SMILES Cc1cc2CCN(C(=O)Nc3ccc(Oc4cnccc4Cl)nc3)c2cc1Cl
Show InChI InChI=1S/C20H16Cl2N4O2/c1-12-8-13-5-7-26(17(13)9-16(12)22)20(27)25-14-2-3-19(24-10-14)28-18-11-23-6-4-15(18)21/h2-4,6,8-11H,5,7H2,1H3,(H,25,27)
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 16n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2A receptor of HEK293 cells by displacement of [3H]ketanserin

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50217971
PNG
(CHEMBL53053)
Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3c2cccc3Br)cn1
Show InChI InChI=1S/C20H17BrN4O2/c1-13-18(6-3-10-22-13)27-19-8-7-14(12-23-19)24-20(26)25-11-9-15-16(21)4-2-5-17(15)25/h2-8,10,12H,9,11H2,1H3,(H,24,26)
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 16n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50217991
PNG
(CHEMBL301012)
Show SMILES Cc1cc2CCN(C(=O)Nc3cnc(Oc4cccnc4C)c(Cl)c3)c2cc1Cl
Show InChI InChI=1S/C21H18Cl2N4O2/c1-12-8-14-5-7-27(18(14)10-16(12)22)21(28)26-15-9-17(23)20(25-11-15)29-19-4-3-6-24-13(19)2/h3-4,6,8-11H,5,7H2,1-2H3,(H,26,28)
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 20n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-HT2B receptor of HEK293 cells by displacement of [3H]5-HT

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50217977
PNG
(CHEMBL55331)
Show SMILES Cc1ccncc1Oc1ccc(NC(=O)N2CCc3cc(C)c(Cl)cc23)cn1
Show InChI InChI=1S/C21H19ClN4O2/c1-13-5-7-23-12-19(13)28-20-4-3-16(11-24-20)25-21(27)26-8-6-15-9-14(2)17(22)10-18(15)26/h3-5,7,9-12H,6,8H2,1-2H3,(H,25,27)
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 32n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-HT2B receptor of HEK293 cells by displacement of [3H]5-HT

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50217981
PNG
(CHEMBL55964)
Show SMILES Cc1cc2CCN(C(=O)Nc3cnc(Oc4cccnc4C)c(C)c3)c2cc1Cl
Show InChI InChI=1S/C22H21ClN4O2/c1-13-9-16-6-8-27(19(16)11-18(13)23)22(28)26-17-10-14(2)21(25-12-17)29-20-5-4-7-24-15(20)3/h4-5,7,9-12H,6,8H2,1-3H3,(H,26,28)
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 32n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-HT2B receptor of HEK293 cells by displacement of [3H]5-HT

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50217972
PNG
(CHEMBL55079)
Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3c2cc(Cl)c(C)c3Cl)cn1
Show InChI InChI=1S/C21H18Cl2N4O2/c1-12-16(22)10-17-15(20(12)23)7-9-27(17)21(28)26-14-5-6-19(25-11-14)29-18-4-3-8-24-13(18)2/h3-6,8,10-11H,7,9H2,1-2H3,(H,26,28)
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 40n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-HT2B receptor of HEK293 cells by displacement of [3H]5-HT

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2C


(Homo sapiens (Human))		BDBM50321864
PNG
(5-Fluoro-2,3-dihydro-indole-1-carboxylic acid [6-(...)
Show SMILES Cc1ncccc1Oc1ccc(NC(=O)N2CCc3cc(F)ccc23)cn1
Show InChI InChI=1S/C20H17FN4O2/c1-13-18(3-2-9-22-13)27-19-7-5-16(12-23-19)24-20(26)25-10-8-14-11-15(21)4-6-17(14)25/h2-7,9,11-12H,8,10H2,1H3,(H,24,26)
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 40n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-hydroxytryptamine 2C receptor of HEK293 cells by displacement of [3H]mesulergine

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50217989
PNG
(CHEMBL56508)
Show SMILES Cc1cc2CCN(C(=O)Nc3cnc(Oc4cccnc4C)c(Cl)c3)c2cc1C(F)(F)F
Show InChI InChI=1S/C22H18ClF3N4O2/c1-12-8-14-5-7-30(18(14)10-16(12)22(24,25)26)21(31)29-15-9-17(23)20(28-11-15)32-19-4-3-6-27-13(19)2/h3-4,6,8-11H,5,7H2,1-2H3,(H,29,31)
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 40n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-HT2B receptor of HEK293 cells by displacement of [3H]5-HT

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50217990
PNG
(CHEMBL54560)
Show SMILES CSc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4C)nc3)c2cc1C(F)(F)F
Show InChI InChI=1S/C22H19F3N4O2S/c1-13-18(4-3-8-26-13)31-20-6-5-15(12-27-20)28-21(30)29-9-7-14-10-19(32-2)16(11-17(14)29)22(23,24)25/h3-6,8,10-12H,7,9H2,1-2H3,(H,28,30)
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 40n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-HT2B receptor of HEK293 cells by displacement of [3H]5-HT

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50217986
PNG
(CHEMBL294030)
Show SMILES Cc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4Cl)nc3)c2cc1Cl
Show InChI InChI=1S/C20H16Cl2N4O2/c1-12-9-13-6-8-26(16(13)10-15(12)21)20(27)25-14-4-5-18(24-11-14)28-17-3-2-7-23-19(17)22/h2-5,7,9-11H,6,8H2,1H3,(H,25,27)
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 50n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-HT2B receptor of HEK293 cells by displacement of [3H]5-HT

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50086071
PNG
(5-Methoxy-6-trifluoromethyl-2,3-dihydro-indole-1-c...)
Show SMILES COc1cc2CCN(C(=O)Nc3ccc(Oc4cccnc4C)nc3)c2cc1C(F)(F)F
Show InChI InChI=1S/C22H19F3N4O3/c1-13-18(4-3-8-26-13)32-20-6-5-15(12-27-20)28-21(30)29-9-7-14-10-19(31-2)16(11-17(14)29)22(23,24)25/h3-6,8,10-12H,7,9H2,1-2H3,(H,28,30)
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 50n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-HT2B receptor of HEK293 cells by displacement of [3H]5-HT

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
5-hydroxytryptamine receptor 2B


(Homo sapiens (Human))		BDBM50217988
PNG
(CHEMBL55792)
Show SMILES CCc1ncccc1Oc1ccc(NC(=O)N2CCc3cc(C)c(Cl)cc23)cn1
Show InChI InChI=1S/C22H21ClN4O2/c1-3-18-20(5-4-9-24-18)29-21-7-6-16(13-25-21)26-22(28)27-10-8-15-11-14(2)17(23)12-19(15)27/h4-7,9,11-13H,3,8,10H2,1-2H3,(H,26,28)
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 50n/an/an/an/an/an/an/an/a



SmithKline Beecham Pharmaceuticals

Curated by ChEMBL


Assay Description
Binding affinity towards human cloned 5-HT2B receptor of HEK293 cells by displacement of [3H]5-HT

Bioorg Med Chem Lett 10: 1863-6 (2000)


BindingDB Entry DOI: 10.7270/Q2X63Q4P
More data for this
Ligand-Target Pair
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