BindingDB PrimarySearch

Found 16 hits Enz. Inhib. hit(s) with all data for entry = 50031987
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Inhibition of human GSK3beta				Eur J Med Chem 45: 3389-93 (2010) Article DOI: 10.1016/j.ejmech.2010.04.026 BindingDB Entry DOI: 10.7270/Q2TH8MWC
Centre Universitaire Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50322830 (CHEMBL1210175 \| N,8-diphenyl-9H-purin-6-amine) Show SMILES N(c1ccccc1)c1ncnc2nc([nH]c12)-c1ccccc1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Inhibition of human GSK3beta				Eur J Med Chem 45: 3389-93 (2010) Article DOI: 10.1016/j.ejmech.2010.04.026 BindingDB Entry DOI: 10.7270/Q2TH8MWC
Centre Universitaire Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50322829 (3-(6-(phenylamino)-9H-purin-8-yl)benzonitrile \| CH...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Inhibition of human GSK3beta				Eur J Med Chem 45: 3389-93 (2010) Article DOI: 10.1016/j.ejmech.2010.04.026 BindingDB Entry DOI: 10.7270/Q2TH8MWC
Centre Universitaire Curated by ChEMBL					More data for this Ligand-Target Pair
Insulin-like growth factor 1 receptor (Homo sapiens (Human))	BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	35.0	n/a	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Inhibition of IGF1R				Eur J Med Chem 45: 3389-93 (2010) Article DOI: 10.1016/j.ejmech.2010.04.026 BindingDB Entry DOI: 10.7270/Q2TH8MWC
Centre Universitaire Curated by ChEMBL					More data for this Ligand-Target Pair
MAP kinase-activated protein kinase 2 (Homo sapiens (Human))	BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	36.3	n/a	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Inhibition of MAPKAPK2				Eur J Med Chem 45: 3389-93 (2010) Article DOI: 10.1016/j.ejmech.2010.04.026 BindingDB Entry DOI: 10.7270/Q2TH8MWC
Centre Universitaire Curated by ChEMBL					More data for this Ligand-Target Pair				3D Structure (docked)
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	49.0	n/a	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Inhibition of TYRO3/SKY				Eur J Med Chem 45: 3389-93 (2010) Article DOI: 10.1016/j.ejmech.2010.04.026 BindingDB Entry DOI: 10.7270/Q2TH8MWC
Centre Universitaire Curated by ChEMBL					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	102	n/a	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Inhibition of EGFR				Eur J Med Chem 45: 3389-93 (2010) Article DOI: 10.1016/j.ejmech.2010.04.026 BindingDB Entry DOI: 10.7270/Q2TH8MWC
Centre Universitaire Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50322826 (CHEMBL1210406 \| N-(8-(naphthalen-2-yl)-9H-purin-6-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	169	n/a	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Inhibition of human GSK3beta				Eur J Med Chem 45: 3389-93 (2010) Article DOI: 10.1016/j.ejmech.2010.04.026 BindingDB Entry DOI: 10.7270/Q2TH8MWC
Centre Universitaire Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50322828 (CHEMBL1210310 \| N-(8-(3-chlorophenyl)-9H-purin-6-y...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	365	n/a	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Inhibition of human GSK3beta				Eur J Med Chem 45: 3389-93 (2010) Article DOI: 10.1016/j.ejmech.2010.04.026 BindingDB Entry DOI: 10.7270/Q2TH8MWC
Centre Universitaire Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50322827 (CHEMBL1210405 \| N-(8-(3-cyanophenyl)-9H-purin-6-yl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	781	n/a	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Inhibition of human GSK3beta				Eur J Med Chem 45: 3389-93 (2010) Article DOI: 10.1016/j.ejmech.2010.04.026 BindingDB Entry DOI: 10.7270/Q2TH8MWC
Centre Universitaire Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50322825 (CHEMBL1210476 \| N-(8-(3-cyanophenyl)-9H-purin-6-yl...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.22E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Inhibition of human GSK3beta				Eur J Med Chem 45: 3389-93 (2010) Article DOI: 10.1016/j.ejmech.2010.04.026 BindingDB Entry DOI: 10.7270/Q2TH8MWC
Centre Universitaire Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 8 (Homo sapiens (Human))	BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.18E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Inhibition of JNK1				Eur J Med Chem 45: 3389-93 (2010) Article DOI: 10.1016/j.ejmech.2010.04.026 BindingDB Entry DOI: 10.7270/Q2TH8MWC
Centre Universitaire Curated by ChEMBL					More data for this Ligand-Target Pair
Casein kinase II subunit alpha (Homo sapiens (Human))	BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) Show SMILES Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.62E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Inhibition of CK2alpha				Eur J Med Chem 45: 3389-93 (2010) Article DOI: 10.1016/j.ejmech.2010.04.026 BindingDB Entry DOI: 10.7270/Q2TH8MWC
Centre Universitaire Curated by ChEMBL					More data for this Ligand-Target Pair
Casein kinase I isoform alpha (Homo sapiens (Human))	BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Inhibition of CK1alpha1				Eur J Med Chem 45: 3389-93 (2010) Article DOI: 10.1016/j.ejmech.2010.04.026 BindingDB Entry DOI: 10.7270/Q2TH8MWC
Centre Universitaire Curated by ChEMBL					More data for this Ligand-Target Pair
Mitogen-activated protein kinase 3 (Homo sapiens (Human))	BDBM50059889 ((staurosporine)3-methoxy-2-methyl-4-methylamino-(2...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	5.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Inhibition of ERK1				Eur J Med Chem 45: 3389-93 (2010) Article DOI: 10.1016/j.ejmech.2010.04.026 BindingDB Entry DOI: 10.7270/Q2TH8MWC
Centre Universitaire Curated by ChEMBL					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM50322824 (CHEMBL1210477 \| N-(8-(naphthalen-2-yl)-9H-purin-6-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Centre Universitaire Curated by ChEMBL					Assay Description Inhibition of human GSK3beta				Eur J Med Chem 45: 3389-93 (2010) Article DOI: 10.1016/j.ejmech.2010.04.026 BindingDB Entry DOI: 10.7270/Q2TH8MWC
Centre Universitaire Curated by ChEMBL					More data for this Ligand-Target Pair